DK0594702T3 - Substituerede indoler som midler mod AIDS - Google Patents
Substituerede indoler som midler mod AIDSInfo
- Publication number
- DK0594702T3 DK0594702T3 DK92915109.0T DK92915109T DK0594702T3 DK 0594702 T3 DK0594702 T3 DK 0594702T3 DK 92915109 T DK92915109 T DK 92915109T DK 0594702 T3 DK0594702 T3 DK 0594702T3
- Authority
- DK
- Denmark
- Prior art keywords
- aids
- agents
- substituted indoles
- indoles
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/14—Antivirals for RNA viruses
- A61P31/18—Antivirals for RNA viruses for HIV
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/04—Immunostimulants
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/14—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing three or more hetero rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Immunology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Virology (AREA)
- Pharmacology & Pharmacy (AREA)
- Oncology (AREA)
- Communicable Diseases (AREA)
- Tropical Medicine & Parasitology (AREA)
- Molecular Biology (AREA)
- AIDS & HIV (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US72505391A | 1991-07-03 | 1991-07-03 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0594702T3 true DK0594702T3 (da) | 1997-07-21 |
Family
ID=24912968
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK92915109.0T DK0594702T3 (da) | 1991-07-03 | 1992-06-23 | Substituerede indoler som midler mod AIDS |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0594702B1 (ko) |
| JP (1) | JP3119485B2 (ko) |
| KR (1) | KR100236808B1 (ko) |
| AT (1) | ATE148464T1 (ko) |
| AU (1) | AU653855B2 (ko) |
| CA (1) | CA2109934C (ko) |
| DE (1) | DE69217224T2 (ko) |
| DK (1) | DK0594702T3 (ko) |
| ES (1) | ES2097341T3 (ko) |
| GR (1) | GR3023040T3 (ko) |
| WO (1) | WO1993001181A1 (ko) |
Families Citing this family (33)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| ATE162523T1 (de) * | 1993-03-26 | 1998-02-15 | Upjohn Co | Wasserchathrate von piperazinylpyridin |
| TW406075B (en) * | 1994-12-13 | 2000-09-21 | Upjohn Co | Alkyl substituted piperidinyl and piperazinyl anti-AIDS compounds |
| UA56992C2 (uk) * | 1995-05-08 | 2003-06-16 | Фармація Енд Апджон Компані | <font face="Symbol">a</font>-ПІРИМІДИНТІОАЛКІЛЗАМІЩЕНІ ТА <font face="Symbol">a</font>-ПІРИМІДИНОКСОАЛКІЛЗАМІЩЕНІ СПОЛУКИ |
| JP2002536291A (ja) * | 1997-08-15 | 2002-10-29 | ファイザー・プロダクツ・インク | ２−（４−アリール又はヘテロアリール−ピペラジン−１−イルメチル）−１ｈ−インドール誘導体 |
| WO1999021834A1 (en) * | 1997-10-27 | 1999-05-06 | Neurosearch A/S | Heteroaryl diazacycloalkanes as cholinergic ligands at nicotinic acetylcholine receptors |
| US6469006B1 (en) * | 1999-06-15 | 2002-10-22 | Bristol-Myers Squibb Company | Antiviral indoleoxoacetyl piperazine derivatives |
| US6476034B2 (en) | 2000-02-22 | 2002-11-05 | Bristol-Myers Squibb Company | Antiviral azaindole derivatives |
| US6573262B2 (en) | 2000-07-10 | 2003-06-03 | Bristol-Myers Sqibb Company | Composition and antiviral activity of substituted indoleoxoacetic piperazine derivatives |
| US20030207910A1 (en) | 2001-02-02 | 2003-11-06 | Tao Wang | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives |
| US20040110785A1 (en) | 2001-02-02 | 2004-06-10 | Tao Wang | Composition and antiviral activity of substituted azaindoleoxoacetic piperazine derivatives |
| US6825201B2 (en) | 2001-04-25 | 2004-11-30 | Bristol-Myers Squibb Company | Indole, azaindole and related heterocyclic amidopiperazine derivatives |
| US20030236277A1 (en) | 2002-02-14 | 2003-12-25 | Kadow John F. | Indole, azaindole and related heterocyclic pyrrolidine derivatives |
| US7037913B2 (en) | 2002-05-01 | 2006-05-02 | Bristol-Myers Squibb Company | Bicyclo 4.4.0 antiviral derivatives |
| US7348337B2 (en) | 2002-05-28 | 2008-03-25 | Bristol-Myers Squibb Company | Indole, azaindole and related heterocyclic 4-alkenyl piperidine amides |
| US6900206B2 (en) | 2002-06-20 | 2005-05-31 | Bristol-Myers Squibb Company | Indole, azaindole and related heterocyclic sulfonylureido piperazine derivatives |
| AU2004234158B2 (en) | 2003-04-29 | 2010-01-28 | Pfizer Inc. | 5,7-diaminopyrazolo[4,3-D]pyrimidines useful in the treatment of hypertension |
| US20050075364A1 (en) | 2003-07-01 | 2005-04-07 | Kap-Sun Yeung | Indole, azaindole and related heterocyclic N-substituted piperazine derivatives |
| US7572799B2 (en) | 2003-11-24 | 2009-08-11 | Pfizer Inc | Pyrazolo[4,3-d]pyrimidines as Phosphodiesterase Inhibitors |
| JP2007532526A (ja) | 2004-04-07 | 2007-11-15 | ファイザー・インク | ピラゾロ［４，３−ｄ］ピリミジン類 |
| WO2006034279A1 (en) | 2004-09-20 | 2006-03-30 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as therapeutic agents |
| AU2005329423A1 (en) | 2004-09-20 | 2006-09-28 | Xenon Pharmaceuticals Inc. | Heterocyclic derivatives and their use as stearoyl-CoA desaturase inhibitors |
| TW200626155A (en) | 2004-09-20 | 2006-08-01 | Xenon Pharmaceuticals Inc | Heterocyclic derivatives and their use as therapeutic agents |
| BRPI0515478A (pt) | 2004-09-20 | 2008-07-22 | Xenon Pharmaceuticals Inc | derivados heterocìclicos e seu uso como mediadores de estearoil-coa-desaturase |
| CN101084207A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 杂环衍生物及其作为硬脂酰CoA去饱和酶抑制剂的用途 |
| TW200626154A (en) | 2004-09-20 | 2006-08-01 | Xenon Pharmaceuticals Inc | Heterocyclic derivatives and their use as therapeutic agents |
| CN101083982A (zh) | 2004-09-20 | 2007-12-05 | 泽农医药公司 | 用于治疗硬脂酰CoA去饱和酶介导的疾病的杂环衍生物 |
| US20060100432A1 (en) | 2004-11-09 | 2006-05-11 | Matiskella John D | Crystalline materials of 1-(4-benzoyl-piperazin-1-yl)-2-[4-methoxy-7-(3-methyl-[1,2,4]triazol-1-yl)-1H-pyrrolo[2,3-c]pyridin-3-yl]-ethane-1,2-dione |
| BRPI0611187A2 (pt) | 2005-06-03 | 2010-08-24 | Xenon Pharmaceuticals Inc | derivados aminotiazàis como inibidores da estearoil-coa desaturase humana |
| DE102005033103A1 (de) * | 2005-07-15 | 2007-01-25 | Bayer Healthcare Ag | Heterocyclylamid-substituierte Thiazole, Pyrrole und Thiophene |
| US7851476B2 (en) | 2005-12-14 | 2010-12-14 | Bristol-Myers Squibb Company | Crystalline forms of 1-benzoyl-4-[2-[4-methoxy-7-(3-methyl-1H-1,2,4-triazol-1-YL)-1-[(phosphonooxy)methyl]-1H-pyrrolo[2,3-C]pyridin-3-YL]-1,2-dioxoethyl]-piperazine |
| CN100463907C (zh) * | 2006-02-10 | 2009-02-25 | 上海医药工业研究院 | 一种1-(5-硝基-1h-吲哚-2-羰基)-4-{3-[(1-甲基乙基)氨基]-2-吡啶}哌嗪的制备方法 |
| US7807671B2 (en) | 2006-04-25 | 2010-10-05 | Bristol-Myers Squibb Company | Diketo-piperazine and piperidine derivatives as antiviral agents |
| CN109776403B (zh) * | 2019-02-22 | 2022-06-14 | 吉林大学 | 一种制备1-叔丁氧羰基-4-[3-(烷基胺基)-2-吡啶基]哌嗪的方法 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4302589A (en) * | 1980-05-08 | 1981-11-24 | American Cyanamid Company | Cis-mono and disubstituted-2-methyl-3-[(piperazinyl) and (piperidino)ethyl]indolines, intermediates for their preparation and methods of preparation |
| AU654808B2 (en) * | 1989-12-28 | 1994-11-24 | Pharmacia & Upjohn Company | Diaromatic substituted anti-aids compounds |
-
1992
- 1992-06-23 DE DE69217224T patent/DE69217224T2/de not_active Expired - Fee Related
- 1992-06-23 AU AU22934/92A patent/AU653855B2/en not_active Ceased
- 1992-06-23 JP JP05502222A patent/JP3119485B2/ja not_active Expired - Fee Related
- 1992-06-23 DK DK92915109.0T patent/DK0594702T3/da active
- 1992-06-23 WO PCT/US1992/005067 patent/WO1993001181A1/en active IP Right Grant
- 1992-06-23 AT AT92915109T patent/ATE148464T1/de not_active IP Right Cessation
- 1992-06-23 CA CA002109934A patent/CA2109934C/en not_active Expired - Fee Related
- 1992-06-23 KR KR1019930704113A patent/KR100236808B1/ko not_active IP Right Cessation
- 1992-06-23 EP EP92915109A patent/EP0594702B1/en not_active Expired - Lifetime
- 1992-06-23 ES ES92915109T patent/ES2097341T3/es not_active Expired - Lifetime
-
1997
- 1997-04-03 GR GR970400707T patent/GR3023040T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| KR100236808B1 (ko) | 2000-02-01 |
| EP0594702B1 (en) | 1997-01-29 |
| AU2293492A (en) | 1993-02-11 |
| JP3119485B2 (ja) | 2000-12-18 |
| AU653855B2 (en) | 1994-10-13 |
| CA2109934C (en) | 2002-12-10 |
| WO1993001181A1 (en) | 1993-01-21 |
| EP0594702A1 (en) | 1994-05-04 |
| GR3023040T3 (en) | 1997-07-30 |
| CA2109934A1 (en) | 1993-01-21 |
| DE69217224T2 (de) | 1997-06-05 |
| ATE148464T1 (de) | 1997-02-15 |
| ES2097341T3 (es) | 1997-04-01 |
| DE69217224D1 (de) | 1997-03-13 |
| JPH06509098A (ja) | 1994-10-13 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DK0594702T3 (da) | Substituerede indoler som midler mod AIDS | |
| FI960399A0 (fi) | Perhydroisoindolijohdannaisia P-aineen antagonisteina | |
| ES2079719T3 (es) | Derivados de amidinofenilalanina, procedimiento para su preparacion, su utilizacion y agentes que los contienen en calidad de anticoagulantes. | |
| ES2135347B1 (es) | Hidroxifeniltriazinas. | |
| YU25497A (sh) | Postupak za dobijanje sildenafila | |
| FI932103A0 (fi) | Nya 4-arylpiperaziner och 4-arylpiperidiner | |
| ECSP045104A (es) | Ligandos de los receptores de los cannabinoides | |
| EA199900373A2 (ru) | Фармацевтические композиции | |
| ES2088537T3 (es) | Derivados de piranil cianoguanidina. | |
| ATE195737T1 (de) | Antagonisten des fibrinogenrezeptors | |
| BR9106518A (pt) | Preparacao de piperidinas substituidas | |
| MX9204342A (es) | Indoles. | |
| IS4367A (is) | CCK eða gastrín temprandi 5-heterósýklísk-1,5-bensódíazepín | |
| DK0660822T3 (da) | Cykliske benzylamino-, benzylamido- og benzylimidoderivater som antipsykotiske midler | |
| DK0745081T3 (da) | Indan-2-mercaptoacetylamiddisulfidderivater, der er anvendelige som enkephalinase-inhibitorer | |
| FI970449A0 (fi) | N-substituoituja atsabisykloheptaanijohdannaisia, jotka ovat käyttökelpoisia neuroleptisinä aineina | |
| ES2123739T3 (es) | Nuevos analogos del eburnano, su procedimiento de preparacion y composiciones farmaceuticas que los contienen. | |
| ES2092112T3 (es) | Agentes hipoglicemicos de tiazolidindiona. | |
| FI960929A (fi) | Välituotteena käyttökelpoiset indolonijohdannaiset | |
| CY1110529T1 (el) | Παρασκευη ν-υποκατεστημενων 2,7-διαλκυλο-4-υδροξυ-5-αμινο-8-αρυλοοκτανοϋλαμιδιων |