DK0586385T3 - Fremgangsmåde til spaltning af enantiomere på chirale spaltningsfaser ved hjælp af en kontinuerlig modstrøms-chromatografifremgangsmåde - Google Patents

Fremgangsmåde til spaltning af enantiomere på chirale spaltningsfaser ved hjælp af en kontinuerlig modstrøms-chromatografifremgangsmåde

Info

Publication number
DK0586385T3
DK0586385T3 DK92905421.1T DK92905421T DK0586385T3 DK 0586385 T3 DK0586385 T3 DK 0586385T3 DK 92905421 T DK92905421 T DK 92905421T DK 0586385 T3 DK0586385 T3 DK 0586385T3
Authority
DK
Denmark
Prior art keywords
cleavage
chiral
enantiomers
phases
chromatography method
Prior art date
Application number
DK92905421.1T
Other languages
English (en)
Other versions
DK0586385T4 (da
Inventor
Dieter Arlt
Walter Lange
Bruno Boemer
Rolf Grosser
Hanns-Ingolf Paul
Guenter Schnabel
Original Assignee
Bayer Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
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Application filed by Bayer Ag filed Critical Bayer Ag
Publication of DK0586385T3 publication Critical patent/DK0586385T3/da
Application granted granted Critical
Publication of DK0586385T4 publication Critical patent/DK0586385T4/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D263/00Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/08Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
    • C07D263/16Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D263/18Oxygen atoms
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/10Selective adsorption, e.g. chromatography characterised by constructional or operational features
    • B01D15/18Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
    • B01D15/1814Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns recycling of the fraction to be distributed
    • B01D15/1821Simulated moving beds
    • B01D15/185Simulated moving beds characterized by the components to be separated
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07BGENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
    • C07B57/00Separation of optically-active compounds
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C231/00Preparation of carboxylic acid amides
    • C07C231/16Preparation of optical isomers
    • C07C231/20Preparation of optical isomers by separation of optical isomers
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D15/00Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
    • B01D15/08Selective adsorption, e.g. chromatography
    • B01D15/26Selective adsorption, e.g. chromatography characterised by the separation mechanism
    • B01D15/38Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
    • B01D15/3833Chiral chromatography
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2215/00Separating processes involving the treatment of liquids with adsorbents
    • B01D2215/02Separating processes involving the treatment of liquids with adsorbents with moving adsorbents
    • B01D2215/023Simulated moving beds
    • BPERFORMING OPERATIONS; TRANSPORTING
    • B01PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
    • B01DSEPARATION
    • B01D2215/00Separating processes involving the treatment of liquids with adsorbents
    • B01D2215/02Separating processes involving the treatment of liquids with adsorbents with moving adsorbents
    • B01D2215/023Simulated moving beds
    • B01D2215/024Provisions to deal with recirculated volumes, e.g. in order to regulate flow

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Analytical Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Sustainable Development (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Treatment Of Liquids With Adsorbents In General (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Solid-Sorbent Or Filter-Aiding Compositions (AREA)
DK92905421T 1991-03-14 1992-02-28 Fremgangsmåde til spaltning af enantiomere på chirale spaltningsfaser ved hjælp af en kontinuerlig modströms-chromatografifremgangsmåde DK0586385T4 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4108188 1991-03-14

Publications (2)

Publication Number Publication Date
DK0586385T3 true DK0586385T3 (da) 1997-04-01
DK0586385T4 DK0586385T4 (da) 2005-04-18

Family

ID=6427227

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92905421T DK0586385T4 (da) 1991-03-14 1992-02-28 Fremgangsmåde til spaltning af enantiomere på chirale spaltningsfaser ved hjælp af en kontinuerlig modströms-chromatografifremgangsmåde

Country Status (7)

Country Link
EP (1) EP0586385B2 (da)
AT (1) ATE144909T1 (da)
DE (1) DE59207503D1 (da)
DK (1) DK0586385T4 (da)
ES (1) ES2094346T5 (da)
GR (1) GR3021891T3 (da)
WO (1) WO1992016274A1 (da)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0577079B1 (en) * 1992-06-30 1999-12-01 Daicel Chemical Industries, Ltd. Simulated moving bed separation system
FR2699917B1 (fr) * 1992-12-30 1995-01-27 Inst Francais Du Petrole Méthode et dispositif de régulation d'un procédé de séparation d'isomères d'hydrocarbures aromatiques à 8 à 10 atomes de carbone.
US5470464A (en) * 1994-04-06 1995-11-28 Uop Small scale simulated moving bed separation apparatus and process
JPH07285889A (ja) * 1994-04-20 1995-10-31 Daicel Chem Ind Ltd 光学異性体の分離方法
JPH09206502A (ja) 1995-12-01 1997-08-12 Daicel Chem Ind Ltd 擬似移動床式分離装置
US5635072A (en) * 1995-01-31 1997-06-03 Uop Simulated moving bed adsorptive separation process
FR2743002B1 (fr) * 1995-12-27 1998-01-30 Inst Francais Du Petrole Procede de regulation d'au moins un debit de fluide circulant dans une boucle de separation chromatographique en lit mobile simule
EP0880984A1 (en) * 1997-05-28 1998-12-02 Uop Apparatus and process for simulated moving bed adsorptive separation
FR2766385B1 (fr) * 1997-07-24 1999-09-03 Novasep Procede pour le controle de la pression dans un systeme de separation a lit mobile simule
DE10226923A1 (de) 2002-06-17 2003-12-24 Bayer Ag Verfahren zur Enantiomerenanreicherung von cis-8-Benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonan
DE102004025000A1 (de) 2004-05-21 2005-12-08 Bayer Technology Services Gmbh Verfahren zur Herstellung von chemischen und pharmazeutischen Produkten mit integrierter Mehrsäulen-Chromatographie

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3268605A (en) * 1961-11-06 1966-08-23 Universal Oil Prod Co Supervisory control system for a simulated moving bed separation process
DE2500523C2 (de) * 1975-01-08 1985-03-14 Merck Patent Gmbh, 6100 Darmstadt Vernetzte Polymerisate, Verfahren zu ihrer Herstellung und ihre Verwendung
GB1581727A (en) * 1976-12-21 1980-12-17 Shell Int Research Coated marine structure
JPS6041507A (ja) * 1983-08-12 1985-03-05 Mitsubishi Kasei Techno Engineers Kk クロマト分離装置の制御方法
DE3619303A1 (de) * 1986-06-07 1987-12-10 Merck Patent Gmbh Optisch aktive adsorbentien

Also Published As

Publication number Publication date
DE59207503D1 (de) 1996-12-12
ATE144909T1 (de) 1996-11-15
ES2094346T5 (es) 2005-09-16
WO1992016274A1 (de) 1992-10-01
EP0586385B2 (de) 2005-03-30
EP0586385A1 (de) 1994-03-16
DK0586385T4 (da) 2005-04-18
EP0586385B1 (de) 1996-11-06
GR3021891T3 (en) 1997-03-31
ES2094346T3 (es) 1997-01-16

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