ES2094346T3 - Procedimiento para la separacion de enantiomeros sobre fases de separacion quirales con ayuda de un procedimiento cromatografico a contra-corriente en continuo. - Google Patents
Procedimiento para la separacion de enantiomeros sobre fases de separacion quirales con ayuda de un procedimiento cromatografico a contra-corriente en continuo.Info
- Publication number
- ES2094346T3 ES2094346T3 ES92905421T ES92905421T ES2094346T3 ES 2094346 T3 ES2094346 T3 ES 2094346T3 ES 92905421 T ES92905421 T ES 92905421T ES 92905421 T ES92905421 T ES 92905421T ES 2094346 T3 ES2094346 T3 ES 2094346T3
- Authority
- ES
- Spain
- Prior art keywords
- separation
- procedure
- continuous
- chasal
- contro
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
- C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
- C07D263/08—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member
- C07D263/16—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having one double bond between ring members or between a ring member and a non-ring member with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D263/18—Oxygen atoms
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/10—Selective adsorption, e.g. chromatography characterised by constructional or operational features
- B01D15/18—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns
- B01D15/1814—Selective adsorption, e.g. chromatography characterised by constructional or operational features relating to flow patterns recycling of the fraction to be distributed
- B01D15/1821—Simulated moving beds
- B01D15/185—Simulated moving beds characterized by the components to be separated
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C231/00—Preparation of carboxylic acid amides
- C07C231/16—Preparation of optical isomers
- C07C231/20—Preparation of optical isomers by separation of optical isomers
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D15/00—Separating processes involving the treatment of liquids with solid sorbents; Apparatus therefor
- B01D15/08—Selective adsorption, e.g. chromatography
- B01D15/26—Selective adsorption, e.g. chromatography characterised by the separation mechanism
- B01D15/38—Selective adsorption, e.g. chromatography characterised by the separation mechanism involving specific interaction not covered by one or more of groups B01D15/265 - B01D15/36
- B01D15/3833—Chiral chromatography
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2215/00—Separating processes involving the treatment of liquids with adsorbents
- B01D2215/02—Separating processes involving the treatment of liquids with adsorbents with moving adsorbents
- B01D2215/023—Simulated moving beds
-
- B—PERFORMING OPERATIONS; TRANSPORTING
- B01—PHYSICAL OR CHEMICAL PROCESSES OR APPARATUS IN GENERAL
- B01D—SEPARATION
- B01D2215/00—Separating processes involving the treatment of liquids with adsorbents
- B01D2215/02—Separating processes involving the treatment of liquids with adsorbents with moving adsorbents
- B01D2215/023—Simulated moving beds
- B01D2215/024—Provisions to deal with recirculated volumes, e.g. in order to regulate flow
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Analytical Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Sustainable Development (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Treatment Of Liquids With Adsorbents In General (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Solid-Sorbent Or Filter-Aiding Compositions (AREA)
Abstract
EN UN PROCEDIMIENTO DE CROMATOGRAFIA EN CONTRACORRIENTE FUNCIONAMIENTO EN CONTINUO SE PRODUCE UN MOVIMIENTO RELATIVO ENTRE EL ABSORBENTE CONSISTENTE EN UNA FASE SOLIDA Y UNA FASE LIQUIDA MOVIL EN COLUMNAS DE CROMATOGRAFIA CONECTADAS UNA TRAS OTRA A TRAVES DE APERTURAS SECUENCIALES DE POSICIONES DE TOMA Y DE ADICION DE LIQUIDOS A LO LARGO DE LAS COLUMNAS DE CROMATOGRAFIA. COMO ABSORBENTE SE EMPLEA UN POLIMERO O MATERIAL QUIRAL SOBRE UN SOPORTE INORGANICO. DE ESTE MODO TIENE EXITO LA SEPARACION DE UNA MEZCLA DE ENANTIOMEROS CON AYUDA DE LA CROMATOGRAFIA EN CONTRACORRIENTE CONTINUA. PARTICULARMENTE DAN BUEN RESULTADO LOS ABSORBENTES DE POLIMERIZADOS RETICULADOS QUE SE OBTIENEN DE ACRILAMIDAS, METACRILAMIDAS Y FLUROACRILAMIDAS OPTICAMENTE ACTIVAS.
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4108188 | 1991-03-14 | ||
DE4108188 | 1991-03-14 |
Publications (2)
Publication Number | Publication Date |
---|---|
ES2094346T3 true ES2094346T3 (es) | 1997-01-16 |
ES2094346T5 ES2094346T5 (es) | 2005-09-16 |
Family
ID=6427227
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES92905421T Expired - Lifetime ES2094346T5 (es) | 1991-03-14 | 1992-02-28 | Procedimiento para la separacion de enantiomeros sobre fases de separacion quirales con ayuda de un procedimiento cromatografico a contra-corriente en continuo. |
Country Status (7)
Country | Link |
---|---|
EP (1) | EP0586385B2 (es) |
AT (1) | ATE144909T1 (es) |
DE (1) | DE59207503D1 (es) |
DK (1) | DK0586385T4 (es) |
ES (1) | ES2094346T5 (es) |
GR (1) | GR3021891T3 (es) |
WO (1) | WO1992016274A1 (es) |
Families Citing this family (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
EP0577079B1 (en) * | 1992-06-30 | 1999-12-01 | Daicel Chemical Industries, Ltd. | Simulated moving bed separation system |
FR2699917B1 (fr) * | 1992-12-30 | 1995-01-27 | Inst Francais Du Petrole | Méthode et dispositif de régulation d'un procédé de séparation d'isomères d'hydrocarbures aromatiques à 8 à 10 atomes de carbone. |
US5470464A (en) * | 1994-04-06 | 1995-11-28 | Uop | Small scale simulated moving bed separation apparatus and process |
JPH07285889A (ja) * | 1994-04-20 | 1995-10-31 | Daicel Chem Ind Ltd | 光学異性体の分離方法 |
JPH09206502A (ja) | 1995-12-01 | 1997-08-12 | Daicel Chem Ind Ltd | 擬似移動床式分離装置 |
US5635072A (en) * | 1995-01-31 | 1997-06-03 | Uop | Simulated moving bed adsorptive separation process |
FR2743002B1 (fr) * | 1995-12-27 | 1998-01-30 | Inst Francais Du Petrole | Procede de regulation d'au moins un debit de fluide circulant dans une boucle de separation chromatographique en lit mobile simule |
EP0880984A1 (en) * | 1997-05-28 | 1998-12-02 | Uop | Apparatus and process for simulated moving bed adsorptive separation |
FR2766385B1 (fr) * | 1997-07-24 | 1999-09-03 | Novasep | Procede pour le controle de la pression dans un systeme de separation a lit mobile simule |
DE10226923A1 (de) | 2002-06-17 | 2003-12-24 | Bayer Ag | Verfahren zur Enantiomerenanreicherung von cis-8-Benzyl-7,9-dioxo-2,8-diazabicyclo[4.3.0]nonan |
DE102004025000A1 (de) | 2004-05-21 | 2005-12-08 | Bayer Technology Services Gmbh | Verfahren zur Herstellung von chemischen und pharmazeutischen Produkten mit integrierter Mehrsäulen-Chromatographie |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3268605A (en) * | 1961-11-06 | 1966-08-23 | Universal Oil Prod Co | Supervisory control system for a simulated moving bed separation process |
DE2500523C2 (de) * | 1975-01-08 | 1985-03-14 | Merck Patent Gmbh, 6100 Darmstadt | Vernetzte Polymerisate, Verfahren zu ihrer Herstellung und ihre Verwendung |
GB1581727A (en) * | 1976-12-21 | 1980-12-17 | Shell Int Research | Coated marine structure |
JPS6041507A (ja) * | 1983-08-12 | 1985-03-05 | Mitsubishi Kasei Techno Engineers Kk | クロマト分離装置の制御方法 |
DE3619303A1 (de) * | 1986-06-07 | 1987-12-10 | Merck Patent Gmbh | Optisch aktive adsorbentien |
-
1992
- 1992-02-28 AT AT92905421T patent/ATE144909T1/de not_active IP Right Cessation
- 1992-02-28 DE DE59207503T patent/DE59207503D1/de not_active Expired - Fee Related
- 1992-02-28 EP EP92905421A patent/EP0586385B2/de not_active Expired - Lifetime
- 1992-02-28 WO PCT/EP1992/000439 patent/WO1992016274A1/de active IP Right Grant
- 1992-02-28 DK DK92905421T patent/DK0586385T4/da active
- 1992-02-28 ES ES92905421T patent/ES2094346T5/es not_active Expired - Lifetime
-
1996
- 1996-12-04 GR GR960403312T patent/GR3021891T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
DE59207503D1 (de) | 1996-12-12 |
ATE144909T1 (de) | 1996-11-15 |
ES2094346T5 (es) | 2005-09-16 |
WO1992016274A1 (de) | 1992-10-01 |
EP0586385B2 (de) | 2005-03-30 |
DK0586385T3 (da) | 1997-04-01 |
EP0586385A1 (de) | 1994-03-16 |
DK0586385T4 (da) | 2005-04-18 |
EP0586385B1 (de) | 1996-11-06 |
GR3021891T3 (en) | 1997-03-31 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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