DK0585419T3 - Fremgangsmåde og apparat til dyrkning af biomassepartikler - Google Patents

Fremgangsmåde og apparat til dyrkning af biomassepartikler

Info

Publication number
DK0585419T3
DK0585419T3 DK93903440T DK93903440T DK0585419T3 DK 0585419 T3 DK0585419 T3 DK 0585419T3 DK 93903440 T DK93903440 T DK 93903440T DK 93903440 T DK93903440 T DK 93903440T DK 0585419 T3 DK0585419 T3 DK 0585419T3
Authority
DK
Denmark
Prior art keywords
culture medium
settling chamber
vessel
particle
agitated
Prior art date
Application number
DK93903440T
Other languages
English (en)
Inventor
Kwan-Min Jem
Pierre-Francois Cevey
Original Assignee
Applied Research Systems
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Applied Research Systems filed Critical Applied Research Systems
Application granted granted Critical
Publication of DK0585419T3 publication Critical patent/DK0585419T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M27/00Means for mixing, agitating or circulating fluids in the vessel
    • C12M27/02Stirrer or mobile mixing elements
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12MAPPARATUS FOR ENZYMOLOGY OR MICROBIOLOGY; APPARATUS FOR CULTURING MICROORGANISMS FOR PRODUCING BIOMASS, FOR GROWING CELLS OR FOR OBTAINING FERMENTATION OR METABOLIC PRODUCTS, i.e. BIOREACTORS OR FERMENTERS
    • C12M33/00Means for introduction, transport, positioning, extraction, harvesting, peeling or sampling of biological material in or from the apparatus
    • C12M33/22Settling tanks; Sedimentation by gravity

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical & Material Sciences (AREA)
  • Zoology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Sustainable Development (AREA)
  • Microbiology (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Molecular Biology (AREA)
  • Apparatus Associated With Microorganisms And Enzymes (AREA)
  • Physical Or Chemical Processes And Apparatus (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DK93903440T 1992-01-17 1993-01-15 Fremgangsmåde og apparat til dyrkning af biomassepartikler DK0585419T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US82230192A 1992-01-17 1992-01-17
PCT/US1993/000272 WO1993014192A1 (en) 1992-01-17 1993-01-15 Method and apparatus for growing biomass particles

Publications (1)

Publication Number Publication Date
DK0585419T3 true DK0585419T3 (da) 2001-03-19

Family

ID=25235685

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93903440T DK0585419T3 (da) 1992-01-17 1993-01-15 Fremgangsmåde og apparat til dyrkning af biomassepartikler

Country Status (15)

Country Link
US (1) US5654197A (da)
EP (1) EP0585419B1 (da)
JP (1) JP3244701B2 (da)
AT (1) ATE197813T1 (da)
AU (1) AU664596B2 (da)
CA (1) CA2106064C (da)
DE (1) DE69329706T2 (da)
DK (1) DK0585419T3 (da)
ES (1) ES2151901T3 (da)
GR (1) GR3035408T3 (da)
HK (1) HK1012674A1 (da)
IL (1) IL104385A (da)
PT (1) PT585419E (da)
WO (1) WO1993014192A1 (da)
ZA (1) ZA93310B (da)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5998184A (en) * 1997-10-08 1999-12-07 Unisyn Technologies, Inc. Basket-type bioreactor
US6335191B1 (en) 1998-02-27 2002-01-01 Nch Corporation Automated system and method for growing bacteria
DE19918409A1 (de) * 1999-04-22 2000-10-26 Forschungszentrum Juelich Gmbh Bioreaktor umfassend einen Medienablauf und einen Rührer sowie Rührer und Medienablauf
US20040185534A1 (en) * 2000-10-02 2004-09-23 Knudsen Ida Molgaard Industrial-scale serum-free production of recombinant proteins in mammalian cells
IL154879A0 (en) * 2000-10-02 2003-10-31 Novo Nordisk As Factor vii glycoforms
US20040185535A1 (en) * 2003-03-21 2004-09-23 Giles Wilson Industrial-scale serum-free production of recombinant FVII in mammalian cells
US20020179544A1 (en) * 2001-04-27 2002-12-05 Nexell Therapeutics, Inc. Cell processing and fluid transfer apparatus and method of use
HUP0402158A2 (hu) * 2001-10-02 2005-01-28 Novo Nordisk Health Care Ag Rekombináns fehérjék előállítási eljárása eukarióta sejtekben
US7160719B2 (en) 2002-06-07 2007-01-09 Mayo Foundation For Medical Education And Research Bioartificial liver system
CN1300297C (zh) * 2002-09-20 2007-02-14 华东理工大学 一种用于动物细胞扩大接种的消化反应器
US7081361B2 (en) * 2003-08-07 2006-07-25 Nch Corporation Biomass generator
US20080020049A1 (en) * 2005-02-25 2008-01-24 Andrew Darling Super-sparger microcarrier beads and precision extrusion deposited poly-epsilon-caprolactone structures for biological applications
WO2010105204A2 (en) 2009-03-13 2010-09-16 Mayo Foundation For Medical Education And Research Bioartificial liver
US8961893B2 (en) * 2009-07-07 2015-02-24 Nch Corporation Automated chemical diluter system having disposable components
US8551762B2 (en) 2009-07-07 2013-10-08 Nch Corporation System and apparatus for feeding, solubilizing, growing and discharging a biological material
DE102009026366A1 (de) 2009-08-12 2011-02-17 Technische Universität München Fermentationsbehälter sowie Verfahren und Vorrichtung zur Fermentation
JP5415330B2 (ja) * 2010-03-12 2014-02-12 株式会社日立製作所 生体細胞の培養装置及び培養方法
EP4036207A1 (en) * 2011-01-17 2022-08-03 F. Hoffmann-La Roche AG Use of a separation apparatus in a seed train
US20170096628A1 (en) * 2014-04-14 2017-04-06 Enevor Inc. Conical Impeller and Applications Thereof
US20170218330A1 (en) * 2016-02-01 2017-08-03 Fenwal, Inc. Systems and methods for the separation of cells from microcarriers using a spinning membrane
JP6744161B2 (ja) * 2016-07-19 2020-08-19 株式会社日立プラントサービス 分離装置、培養装置および分離方法
CN114058505A (zh) 2020-07-30 2022-02-18 环球生命科技咨询美国有限责任公司 新型灌流培养用高密度微载体截留装置和使用方法
JP2023003462A (ja) * 2021-06-24 2023-01-17 横河電機株式会社 細胞培養プロセスに使用するための溶液処理デバイス

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR821326A (fr) * 1936-05-04 1937-12-02 Procédé et appareil pour la fermentation continue de solutions, en vue de l'obtention de produits de fermentation ou de micro-organismes qui se multiplient
US2451156A (en) * 1944-06-19 1948-10-12 Mattos Annibal Ramos De Process and apparatus for producing alcohol by fermentation
JPS575690A (en) * 1980-06-13 1982-01-12 Toray Ind Inc Circulation device for culture medium in cultivation tank
US4335215A (en) * 1980-08-27 1982-06-15 Monsanto Company Method of growing anchorage-dependent cells
CS231837B1 (en) * 1982-07-30 1984-12-14 Svatopluk Mackrle Device for a biological water purification
JPS63123379A (ja) * 1986-11-12 1988-05-27 Teijin Ltd 動物細胞の培養方法
US4814278A (en) * 1985-02-05 1989-03-21 Teijin Limited Culture apparatus and method
GB8515636D0 (en) * 1985-06-20 1985-07-24 Celltech Ltd Fermenter
JPH0195769A (ja) * 1987-10-08 1989-04-13 Ebara Res Co Ltd 高濃度培養装置
JPH0380077A (ja) * 1989-08-23 1991-04-04 Meiji Milk Prod Co Ltd マイクロキャリア分離方法及び装置
EP0498858A1 (en) * 1989-11-03 1992-08-19 Massachusetts Institute Of Technology Nested-cone separator
JP3385741B2 (ja) * 1994-08-22 2003-03-10 日本ゼオン株式会社 医用材料組成物、その調製方法及び医用成形物

Also Published As

Publication number Publication date
ES2151901T3 (es) 2001-01-16
ZA93310B (en) 1993-09-08
US5654197A (en) 1997-08-05
IL104385A0 (en) 1993-05-13
EP0585419A1 (en) 1994-03-09
AU664596B2 (en) 1995-11-23
PT585419E (pt) 2001-04-30
WO1993014192A1 (en) 1993-07-22
JP3244701B2 (ja) 2002-01-07
CA2106064C (en) 2005-09-20
EP0585419A4 (en) 1995-04-05
GR3035408T3 (en) 2001-05-31
CA2106064A1 (en) 1993-07-18
EP0585419B1 (en) 2000-11-29
ATE197813T1 (de) 2000-12-15
HK1012674A1 (en) 1999-08-06
DE69329706T2 (de) 2001-03-29
DE69329706D1 (de) 2001-01-04
IL104385A (en) 1995-12-31
AU3470393A (en) 1993-08-03
JPH06510205A (ja) 1994-11-17

Similar Documents

Publication Publication Date Title
DK0585419T3 (da) Fremgangsmåde og apparat til dyrkning af biomassepartikler
Kacena et al. Bacterial growth in space flight: logistic growth curve parameters for Escherichia coli and Bacillus subtilis
JP3583785B2 (ja) 微生物生育工程の制御方法
EP0699101B1 (en) Particle settler for use in mammalian cell culture
DE3661273D1 (en) Method and apparatus for carrying out cell culture
EP0052252A3 (en) Method and apparatus for the submerged culture of cell cultures
CA1322541C (en) Method for releasing cell cultures from the microcarriers
DE3165197D1 (en) Method and apparatus for stirring particles in suspension such as microcarriers for anchorage-dependent living cells in a liquid culture medium
ATE3057T1 (de) Verfahren und anlagen, die hefe verwenden.
JPS5564795A (en) Method and apparatus for culturing living tissue or cell
GB964477A (en) Method and apparatus for settling solid-containing liquids
Cherry et al. Studies and observations on the growth of mammalian cells in agitated fluid medium
JPH0416153B2 (da)
GB2054397B (en) Method and apparatus for stirring particles in suspension such as microcarriers for anchorage-dependent living cells in a liquid culture medium
JPS645486A (en) Cell culture method and apparatus therefor
YU45458B (en) Process for obtaining liquid ethanole extract of propolis
GB2195624B (en) Sewage treatment plant
EP0276154A3 (en) Method and apparatus for cell culture
Mooers Studies on immobilization and product recovery for the magnetically stabilized fluidized bed plant cell bioreactor
CN117757729A (zh) 一种诱导脐带间充质干细胞分化的方法
Badger et al. A Method for the Selection of a Synchronized Population of Cloning HeLa Cells
Johnson [61] Measurement of interferon modulation of the in vitro antibody response
JPS6147184A (ja) 体細胞集積浮遊培養法及びそれに使用する培養器
HUT53935A (en) Process for producing plasminogene activator from cells cultured in lectin containing culture medium
JPH03198727A (ja) 宇宙用藻類培養装置