DK0570575T3 - Bicykloazamakrocyklophosphonsyre, komplekser, konjugater, kontrastmidler og fremstilling heraf - Google Patents
Bicykloazamakrocyklophosphonsyre, komplekser, konjugater, kontrastmidler og fremstilling herafInfo
- Publication number
- DK0570575T3 DK0570575T3 DK93901000T DK93901000T DK0570575T3 DK 0570575 T3 DK0570575 T3 DK 0570575T3 DK 93901000 T DK93901000 T DK 93901000T DK 93901000 T DK93901000 T DK 93901000T DK 0570575 T3 DK0570575 T3 DK 0570575T3
- Authority
- DK
- Denmark
- Prior art keywords
- complexes
- conjugates
- preparation
- contrast agents
- bicycloazamacrocyclophosphonic
- Prior art date
Links
- 239000002253 acid Substances 0.000 title abstract 2
- 239000002872 contrast media Substances 0.000 title abstract 2
- -1 complexes Substances 0.000 title 1
- 102000008394 Immunoglobulin Fragments Human genes 0.000 abstract 1
- 108010021625 Immunoglobulin Fragments Proteins 0.000 abstract 1
- 150000001875 compounds Chemical class 0.000 abstract 1
- 238000001727 in vivo Methods 0.000 abstract 1
- 150000002500 ions Chemical class 0.000 abstract 1
- 239000003446 ligand Substances 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6524—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having four or more nitrogen atoms as the only ring hetero atoms
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Epidemiology (AREA)
- Veterinary Medicine (AREA)
- Molecular Biology (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Optics & Photonics (AREA)
- Medicinal Chemistry (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Radiology & Medical Imaging (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
Applications Claiming Priority (2)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US80555191A | 1991-12-10 | 1991-12-10 | |
| PCT/US1992/010668 WO1993011802A1 (fr) | 1991-12-10 | 1992-12-10 | Acides bicycloazamacrocyclophosphoniques, conjugues, agents de contraste et leur preparation |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0570575T3 true DK0570575T3 (da) | 1998-08-24 |
Family
ID=25191891
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK93901000T DK0570575T3 (da) | 1991-12-10 | 1992-12-10 | Bicykloazamakrocyklophosphonsyre, komplekser, konjugater, kontrastmidler og fremstilling heraf |
Country Status (18)
| Country | Link |
|---|---|
| EP (2) | EP0735040A3 (fr) |
| JP (1) | JPH07502043A (fr) |
| CN (1) | CN1038328C (fr) |
| AT (1) | ATE160943T1 (fr) |
| AU (1) | AU3246893A (fr) |
| CA (1) | CA2103556C (fr) |
| DE (1) | DE69223504T2 (fr) |
| DK (1) | DK0570575T3 (fr) |
| ES (1) | ES2110593T3 (fr) |
| GR (1) | GR3026121T3 (fr) |
| HK (1) | HK1006654A1 (fr) |
| HU (1) | HUT66220A (fr) |
| IL (1) | IL104060A (fr) |
| MX (1) | MX9207166A (fr) |
| RU (1) | RU2114115C1 (fr) |
| SG (1) | SG46598A1 (fr) |
| WO (1) | WO1993011802A1 (fr) |
| ZA (1) | ZA929576B (fr) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5385893A (en) * | 1993-05-06 | 1995-01-31 | The Dow Chemical Company | Tricyclopolyazamacrocyclophosphonic acids, complexes and derivatives thereof, for use as contrast agents |
| JPH08509976A (ja) * | 1993-05-06 | 1996-10-22 | ザ・ダウ・ケミカル・カンパニー | コントラスト剤として使用するためのビシクロポリアザマクロシクロホスホン酸、それらの錯体および複合体ならびにそれらの製造方法 |
| US6207826B1 (en) | 1995-03-27 | 2001-03-27 | Isis Pharmaceuticals, Inc. | Macrocyclic compounds having nitrogen-containing linkages |
| US6107482A (en) * | 1995-03-27 | 2000-08-22 | Isis Pharmaceuticals, Inc. | Nitrogenous macrocyclic compounds |
| US5834456A (en) * | 1996-02-23 | 1998-11-10 | The Dow Chemical Company | Polyazamacrocyclofluoromonoalkylphosphonic acids, and their complexes, for use as contrast agents |
| EP0898574B1 (fr) * | 1996-04-19 | 2003-11-12 | Dow Global Technologies Inc. | Chelates fluorescents utilises en tant qu'agents visuels destines a l'imagerie et specifiques de certains tissus |
| US5888476A (en) * | 1996-11-13 | 1999-03-30 | Mallinckrodt Medical, Inc. | Magnetic resonance blood pool agents |
| US6440389B1 (en) | 2000-07-19 | 2002-08-27 | The General Hospital Corporation | Fluorescent agents for real-time measurement of organ function |
| BRPI0922779A8 (pt) * | 2008-12-05 | 2018-06-19 | Molecular Insight Pharm Inc | complexos de tecnécio e rênio-bis(heteroarila) e métodos de uso dos mesmos para inibir psma |
| NO331773B1 (no) * | 2009-12-18 | 2012-03-26 | Ge Healthcare As | Mangankelater, sammensetninger omfattende slike og anvendelse av disse som kontrastmidler for magnettomografi (MR) |
| GB201610738D0 (en) | 2016-06-20 | 2016-08-03 | Ge Healthcare As | Chelate compounds |
| RU2769699C2 (ru) * | 2016-12-21 | 2022-04-05 | ДжиИ Хелткер АС | Хелатные соединения марганца на основе тетраазабицикло-макроцикла, подходящие в качестве визуализирующих агентов для MRI |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE4001655A1 (de) * | 1990-01-18 | 1991-07-25 | Schering Ag | 6-ring enthaltende makrocyclische tetraaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
| DE3825040A1 (de) * | 1988-07-20 | 1990-01-25 | Schering Ag | 5- oder 6-ring- enthaltende makrocyclische polyaza-verbindungen, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
| FR2644785B1 (fr) * | 1989-03-24 | 1991-07-05 | Guerbet Sa | Nouveaux ligands macrocycliques azotes, procede de preparation, complexes metalliques formes par ces ligands et composition de diagnostic les contenant |
| DE3938992A1 (de) * | 1989-11-21 | 1991-05-23 | Schering Ag | Kaskadenpolymer-gebundene komplexbildner, deren komplexe und konjugate, verfahren zu ihrer herstellung und diese enthaltende pharmazeutische mittel |
| GB9001245D0 (en) * | 1990-01-19 | 1990-03-21 | Salutar Inc | Compounds |
| WO1991010669A1 (fr) * | 1990-01-19 | 1991-07-25 | Cockbain, Julian, Roderick, Michaelson | Composes de chelation |
-
1992
- 1992-12-10 RU RU93053767A patent/RU2114115C1/ru active
- 1992-12-10 HU HU9302312A patent/HUT66220A/hu unknown
- 1992-12-10 IL IL10406092A patent/IL104060A/en not_active IP Right Cessation
- 1992-12-10 SG SG1996006488A patent/SG46598A1/en unknown
- 1992-12-10 ES ES93901000T patent/ES2110593T3/es not_active Expired - Lifetime
- 1992-12-10 DE DE69223504T patent/DE69223504T2/de not_active Expired - Fee Related
- 1992-12-10 EP EP96107948A patent/EP0735040A3/fr not_active Withdrawn
- 1992-12-10 AT AT93901000T patent/ATE160943T1/de not_active IP Right Cessation
- 1992-12-10 JP JP5511072A patent/JPH07502043A/ja active Pending
- 1992-12-10 CN CN92115368A patent/CN1038328C/zh not_active Expired - Fee Related
- 1992-12-10 DK DK93901000T patent/DK0570575T3/da active
- 1992-12-10 WO PCT/US1992/010668 patent/WO1993011802A1/fr active IP Right Grant
- 1992-12-10 MX MX9207166A patent/MX9207166A/es not_active IP Right Cessation
- 1992-12-10 ZA ZA929576A patent/ZA929576B/xx unknown
- 1992-12-10 EP EP93901000A patent/EP0570575B1/fr not_active Expired - Lifetime
- 1992-12-10 CA CA002103556A patent/CA2103556C/fr not_active Expired - Fee Related
- 1992-12-10 AU AU32468/93A patent/AU3246893A/en not_active Abandoned
-
1998
- 1998-02-12 GR GR980400293T patent/GR3026121T3/el unknown
- 1998-06-23 HK HK98106042A patent/HK1006654A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| CA2103556C (fr) | 2002-04-16 |
| ES2110593T3 (es) | 1998-02-16 |
| EP0570575A1 (fr) | 1993-11-24 |
| ZA929576B (en) | 1994-06-10 |
| EP0735040A3 (fr) | 1997-02-26 |
| IL104060A (en) | 1998-12-06 |
| DE69223504D1 (de) | 1998-01-22 |
| GR3026121T3 (en) | 1998-05-29 |
| ATE160943T1 (de) | 1997-12-15 |
| HU9302312D0 (en) | 1993-12-28 |
| CA2103556A1 (fr) | 1993-06-11 |
| HUT66220A (en) | 1994-10-28 |
| WO1993011802A1 (fr) | 1993-06-24 |
| HK1006654A1 (en) | 1999-03-12 |
| AU3246893A (en) | 1993-07-19 |
| JPH07502043A (ja) | 1995-03-02 |
| SG46598A1 (en) | 1998-02-20 |
| EP0735040A2 (fr) | 1996-10-02 |
| DE69223504T2 (de) | 1998-04-02 |
| RU2114115C1 (ru) | 1998-06-27 |
| CN1074447A (zh) | 1993-07-21 |
| CN1038328C (zh) | 1998-05-13 |
| IL104060A0 (en) | 1993-05-13 |
| MX9207166A (es) | 1993-07-01 |
| EP0570575B1 (fr) | 1997-12-10 |
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