MY141501A - Bicyclopolyazamacrocyclophosphonic acids, their complexes and conjugates, for use as contrast agents and processes for their preparation - Google Patents

Bicyclopolyazamacrocyclophosphonic acids, their complexes and conjugates, for use as contrast agents and processes for their preparation

Info

Publication number
MY141501A
MY141501A MYPI92002317A MYPI9202317A MY141501A MY 141501 A MY141501 A MY 141501A MY PI92002317 A MYPI92002317 A MY PI92002317A MY PI9202317 A MYPI9202317 A MY PI9202317A MY 141501 A MY141501 A MY 141501A
Authority
MY
Malaysia
Prior art keywords
complexes
conjugates
processes
preparation
contrast agents
Prior art date
Application number
MYPI92002317A
Inventor
Garry E Kiefer
Jaime Simon
Joseph R Garlich
Original Assignee
Dow Chemical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Dow Chemical Co filed Critical Dow Chemical Co
Priority to MYPI92002317A priority Critical patent/MY141501A/en
Publication of MY141501A publication Critical patent/MY141501A/en

Links

Classifications

    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)

Abstract

BICYCLOPOLYAZAMACROCYCLOPHOSPHONIC ACID COMPOUNDS ARE DISCLOSED WHICH MAY FORM INERT COMPLEXES WITH GD, MN OR FE IONS. THE OVERALL CHARGE OF THE COMPLEX CAN BE VARIED TO ALTER THE IN VIVO BIOLOCALIZATION. SUCH COMPLEXES CAN BE COVALENTLY ATTACHED TO AN ANTIBODY, ANTIBODY FRAGMENT OR OTHER BIOLOGICALLY ACTIVE MOLECULE TO FORM CONJUGATES. THE COMPLEXES AND CONJUGATES ARE USEFUL AS CONTRAST AGENTS FOR DIAGNOSTIC PURPOSES. PROCESSES FOR THE PREPARATION OF THE LIGAND, COMPLEX AND CONJUGATE ARE ALSO DISCLOSED.
MYPI92002317A 1992-12-16 1992-12-16 Bicyclopolyazamacrocyclophosphonic acids, their complexes and conjugates, for use as contrast agents and processes for their preparation MY141501A (en)

Priority Applications (1)

Application Number Priority Date Filing Date Title
MYPI92002317A MY141501A (en) 1992-12-16 1992-12-16 Bicyclopolyazamacrocyclophosphonic acids, their complexes and conjugates, for use as contrast agents and processes for their preparation

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
MYPI92002317A MY141501A (en) 1992-12-16 1992-12-16 Bicyclopolyazamacrocyclophosphonic acids, their complexes and conjugates, for use as contrast agents and processes for their preparation

Publications (1)

Publication Number Publication Date
MY141501A true MY141501A (en) 2010-05-14

Family

ID=47320762

Family Applications (1)

Application Number Title Priority Date Filing Date
MYPI92002317A MY141501A (en) 1992-12-16 1992-12-16 Bicyclopolyazamacrocyclophosphonic acids, their complexes and conjugates, for use as contrast agents and processes for their preparation

Country Status (1)

Country Link
MY (1) MY141501A (en)

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