DK0565377T3 - Terapeutiske midler til behandling af Parkinsons sygdom - Google Patents
Terapeutiske midler til behandling af Parkinsons sygdomInfo
- Publication number
- DK0565377T3 DK0565377T3 DK93302780.7T DK93302780T DK0565377T3 DK 0565377 T3 DK0565377 T3 DK 0565377T3 DK 93302780 T DK93302780 T DK 93302780T DK 0565377 T3 DK0565377 T3 DK 0565377T3
- Authority
- DK
- Denmark
- Prior art keywords
- group
- parkinson
- disease
- treatment
- therapeutic agents
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/12—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1, 3, and 7, e.g. caffeine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/505—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim
- A61K31/519—Pyrimidines; Hydrogenated pyrimidines, e.g. trimethoprim ortho- or peri-condensed with heterocyclic rings
- A61K31/52—Purines, e.g. adenine
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
- C07D473/08—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3 with methyl radicals in positions 1 and 3, e.g. theophylline
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Neurosurgery (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicinal Preparation (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP8711592 | 1992-04-08 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0565377T3 true DK0565377T3 (da) | 1998-03-16 |
Family
ID=13905960
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK93302780.7T DK0565377T3 (da) | 1992-04-08 | 1993-04-08 | Terapeutiske midler til behandling af Parkinsons sygdom |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0565377B1 (ja) |
JP (1) | JP2613352B2 (ja) |
AT (1) | ATE161723T1 (ja) |
BR (1) | BR1100636A (ja) |
CA (1) | CA2093403C (ja) |
DE (1) | DE69316067T2 (ja) |
DK (1) | DK0565377T3 (ja) |
ES (1) | ES2112386T3 (ja) |
GR (1) | GR3026233T3 (ja) |
HK (1) | HK1001835A1 (ja) |
NO (1) | NO303265B1 (ja) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CZ211593A3 (en) * | 1992-02-19 | 1994-03-16 | Yukio Ishida | Rice with high absorption of water, method of its preparation and use |
CA2116967C (en) * | 1992-07-08 | 2003-08-19 | Fumio Suzuki | Antidepressants |
JP2613355B2 (ja) * | 1992-09-28 | 1997-05-28 | 協和醗酵工業株式会社 | パーキンソン氏病治療剤 |
AU6781194A (en) * | 1993-05-03 | 1994-11-21 | United States Of America, Represented By The Secretary, Department Of Health And Human Services, The | 8-substituted 1,3,7-trialkyl-xanthine derivatives as a2-selective adenosine receptor antagonists |
EP0711282B1 (en) * | 1993-07-28 | 2002-06-05 | Aventis Pharma Limited | Compounds as pde iv and tnf inhibitors |
US5703085A (en) * | 1994-02-23 | 1997-12-30 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivatives |
ES2232877T3 (es) * | 1996-08-07 | 2005-06-01 | Kyowa Hakko Kogyo Co., Ltd. | Emulsion grasa que contiene un derivado de xantina. |
ATE325610T1 (de) | 1997-09-05 | 2006-06-15 | Kyowa Hakko Kogyo Kk | Xanthinderivative zur behandlung von hirnischämie |
JP4397691B2 (ja) | 2001-10-30 | 2010-01-13 | コンフォーマ・セラピューティクス・コーポレイション | Hsp90阻害活性を有するプリン類似体 |
US7579331B2 (en) | 2003-04-25 | 2009-08-25 | Novacardia, Inc. | Method of improved diuresis in individuals with impaired renal function |
US7138401B2 (en) | 2003-09-18 | 2006-11-21 | Conforma Therapeutics Corporation | 2-aminopurine analogs having HSP90-inhibiting activity |
US7763625B2 (en) | 2004-01-28 | 2010-07-27 | Kyowa Hakko Kirin Co., Ltd. | Agents for treating migraine |
JP2008534609A (ja) * | 2005-03-30 | 2008-08-28 | コンフォーマ・セラピューティクス・コーポレイション | Hsp90阻害剤としてのアルキニルピロロピリミジンおよび関連類似体 |
KR20080002997A (ko) * | 2005-04-22 | 2008-01-04 | 노바카르디아, 인코포레이션 | 수불용성 약제학적 조성물의 정맥내 주사용 에멀젼의 제조 |
JP2010513353A (ja) * | 2006-12-22 | 2010-04-30 | シュバルツ ファルマ アクチェンゲゼルシャフト | 選択的a2a受容体アンタゴニストとしての8−エチニルキサンチン誘導体 |
US7994357B2 (en) * | 2009-04-03 | 2011-08-09 | Naturewise Biotech & Medicals Corporation | Cinamic compounds and derivatives therefrom for the inhibition of histone deacetylase |
WO2020125779A1 (en) * | 2018-12-21 | 2020-06-25 | Sunshine Lake Pharma Co., Ltd. | 8-substituted styryl xanthine derivatives and uses thereof |
US20220202822A1 (en) * | 2019-04-24 | 2022-06-30 | Sunshine Lake Pharma Co., Ltd. | 8-substituted aryl vinyl xanthine derivatives and uses thereof |
CN110041331B (zh) * | 2019-05-17 | 2020-08-07 | 广东东阳光药业有限公司 | 苯乙烯基黄嘌呤衍生物及其用途 |
CN112409360B (zh) * | 2019-08-22 | 2022-12-23 | 广东东阳光药业有限公司 | 杂芳基乙烯基黄嘌呤衍生物及其用途 |
WO2021093701A1 (en) * | 2019-11-11 | 2021-05-20 | Sunshine Lake Pharma Co., Ltd. | 8-substituted styryl xanthine derivatives and uses thereof |
CN111072663B (zh) * | 2019-12-12 | 2021-10-01 | 广东东阳光药业有限公司 | 8-取代的苯乙烯基黄嘌呤衍生物及其用途 |
CN111018856B (zh) * | 2019-12-12 | 2021-10-01 | 广东东阳光药业有限公司 | 8-取代的苯乙烯基黄嘌呤衍生物及其用途 |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH512487A (fr) * | 1969-07-30 | 1971-09-15 | Parke Davis & Co | Procédé de préparation de xanthines |
DE8817122U1 (de) * | 1988-12-22 | 1993-02-04 | Boehringer Ingelheim Kg, 55218 Ingelheim | Neue Xanthinderivate mit Adenosinantogenistischer Wirkung |
GB8906792D0 (en) * | 1989-03-23 | 1989-05-10 | Beecham Wuelfing Gmbh & Co Kg | Treatment and compounds |
DE4019892A1 (de) * | 1990-06-22 | 1992-01-02 | Boehringer Ingelheim Kg | Neue xanthinderivate |
FR2665636B1 (fr) * | 1990-08-10 | 1994-10-07 | Adir | Utilisation d'un derive de la trimethyl-1,3,7 xanthine pour le traitement des troubles de la memoire, des troubles intellectuels de la senescence et de la maladie d'alzheimer. |
EP0559893B1 (en) * | 1990-10-18 | 1999-02-03 | Kyowa Hakko Kogyo Co., Ltd. | Xanthine derivative |
-
1993
- 1993-04-05 CA CA002093403A patent/CA2093403C/en not_active Expired - Lifetime
- 1993-04-06 NO NO931317A patent/NO303265B1/no not_active IP Right Cessation
- 1993-04-08 EP EP93302780A patent/EP0565377B1/en not_active Expired - Lifetime
- 1993-04-08 DE DE69316067T patent/DE69316067T2/de not_active Expired - Lifetime
- 1993-04-08 JP JP5081953A patent/JP2613352B2/ja not_active Expired - Fee Related
- 1993-04-08 ES ES93302780T patent/ES2112386T3/es not_active Expired - Lifetime
- 1993-04-08 DK DK93302780.7T patent/DK0565377T3/da active
- 1993-04-08 AT AT93302780T patent/ATE161723T1/de not_active IP Right Cessation
-
1997
- 1997-05-13 BR BR1100636-6A patent/BR1100636A/pt active IP Right Grant
-
1998
- 1998-02-04 HK HK98100812A patent/HK1001835A1/xx not_active IP Right Cessation
- 1998-02-25 GR GR980400413T patent/GR3026233T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
JPH0616559A (ja) | 1994-01-25 |
CA2093403A1 (en) | 1993-10-09 |
JP2613352B2 (ja) | 1997-05-28 |
NO931317L (no) | 1993-10-11 |
DE69316067D1 (de) | 1998-02-12 |
CA2093403C (en) | 1999-08-10 |
ES2112386T3 (es) | 1998-04-01 |
HK1001835A1 (en) | 1998-07-10 |
GR3026233T3 (en) | 1998-05-29 |
BR1100636A (pt) | 2000-04-18 |
ATE161723T1 (de) | 1998-01-15 |
EP0565377B1 (en) | 1998-01-07 |
NO931317D0 (no) | 1993-04-06 |
DE69316067T2 (de) | 1998-07-02 |
EP0565377A1 (en) | 1993-10-13 |
NO303265B1 (no) | 1998-06-22 |
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