DK0564093T3 - Hydroxylerede metabolitter og derivater af doxazosin som antiatherosklerosemidler - Google Patents

Hydroxylerede metabolitter og derivater af doxazosin som antiatherosklerosemidler

Info

Publication number
DK0564093T3
DK0564093T3 DK93301505T DK93301505T DK0564093T3 DK 0564093 T3 DK0564093 T3 DK 0564093T3 DK 93301505 T DK93301505 T DK 93301505T DK 93301505 T DK93301505 T DK 93301505T DK 0564093 T3 DK0564093 T3 DK 0564093T3
Authority
DK
Denmark
Prior art keywords
doxazosin
derivatives
hydroxylated metabolites
retarding
development
Prior art date
Application number
DK93301505T
Other languages
Danish (da)
English (en)
Inventor
Samuel Siu-Ming Wong
Archie Calhoun Swindell
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0564093T3 publication Critical patent/DK0564093T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A61K31/498—Pyrazines or piperazines ortho- and peri-condensed with carbocyclic ring systems, e.g. quinoxaline, phenazine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0019—Injectable compositions; Intramuscular, intravenous, arterial, subcutaneous administration; Compositions to be administered through the skin in an invasive manner
    • A61K9/0021—Intradermal administration, e.g. through microneedle arrays, needleless injectors
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/06—Ointments; Bases therefor; Other semi-solid forms, e.g. creams, sticks, gels
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • H—ELECTRICITY
    • H01—ELECTRIC ELEMENTS
    • H01L—SEMICONDUCTOR DEVICES NOT COVERED BY CLASS H10
    • H01L2924/00—Indexing scheme for arrangements or methods for connecting or disconnecting semiconductor or solid-state bodies as covered by H01L24/00
    • H01L2924/15—Details of package parts other than the semiconductor or other solid state devices to be connected
    • H01L2924/181—Encapsulation

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Epidemiology (AREA)
  • Dermatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Urology & Nephrology (AREA)
  • Cardiology (AREA)
  • Vascular Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nutrition Science (AREA)
  • Physiology (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Medicinal Preparation (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Plural Heterocyclic Compounds (AREA)
DK93301505T 1992-04-01 1993-02-26 Hydroxylerede metabolitter og derivater af doxazosin som antiatherosklerosemidler DK0564093T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US86171492A 1992-04-01 1992-04-01

Publications (1)

Publication Number Publication Date
DK0564093T3 true DK0564093T3 (da) 2000-03-27

Family

ID=25336560

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93301505T DK0564093T3 (da) 1992-04-01 1993-02-26 Hydroxylerede metabolitter og derivater af doxazosin som antiatherosklerosemidler

Country Status (17)

Country Link
US (1) US5543411A (ja)
EP (1) EP0564093B1 (ja)
JP (1) JPH0624989A (ja)
KR (1) KR0137927B1 (ja)
AT (1) ATE187069T1 (ja)
AU (1) AU660359B2 (ja)
CA (1) CA2092983C (ja)
DE (1) DE69327128T2 (ja)
DK (1) DK0564093T3 (ja)
ES (1) ES2139624T3 (ja)
GR (1) GR3032373T3 (ja)
HU (1) HU225113B1 (ja)
IL (1) IL105141A (ja)
MX (1) MX9301824A (ja)
NZ (1) NZ247307A (ja)
PT (1) PT564093E (ja)
ZA (1) ZA932307B (ja)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IL120303A0 (en) * 1996-03-27 1997-06-10 Pfizer Use of alpha1-adrenoreceptor antagonists in the prevention and treatment of cancer
IL120302A0 (en) * 1996-03-27 1997-06-10 Pfizer Use of alpha1-adrenoreceptor antagonists in the prevention and treatment of benign prostatic hyperplasia
US6177430B1 (en) 1997-03-27 2001-01-23 Pfizer Inc Use of α1-adrenoreceptor antagonists in the prevention and treatment of benign prostatic hyperplasia
NZ525519A (en) * 2000-09-25 2005-01-28 Cohesion Tech Inc Resorbable anastomosis stents for insertion into an opening in a lumen of a vessel or tissue of a patient
US20050165428A1 (en) * 2000-09-25 2005-07-28 Franco Kenneth L. Absorable surgical structure
CN1826207B (zh) 2003-07-18 2010-06-16 浜松光子学株式会社 激光加工方法、激光加工装置以及加工产品

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB271997A (en) * 1926-04-16 1927-06-09 Morris Engines Coventry Ltd Improvements relating to the driving of cam or other auxiliary shafts in internal combustion engines
US4188390A (en) * 1977-11-05 1980-02-12 Pfizer Inc. Antihypertensive 4-amino-2-[4-(1,4-benzodioxan-2-carbonyl) piperazin-1-yl or homopiperazin-1-yl]quinazolines
GB8506174D0 (en) * 1985-03-09 1985-04-11 Pfizer Ltd 4-amino-6 7-dimethoxy-2-piperazin-1-ylquinazoline derivatives
US4758569A (en) * 1987-08-26 1988-07-19 Pfizer Inc. Doxazosin as an anti-atherosclerosis agent

Also Published As

Publication number Publication date
CA2092983C (en) 1996-12-31
AU3562993A (en) 1993-10-07
IL105141A0 (en) 1993-07-08
JPH0624989A (ja) 1994-02-01
EP0564093B1 (en) 1999-12-01
US5543411A (en) 1996-08-06
CA2092983A1 (en) 1993-10-02
PT564093E (pt) 2000-04-28
ES2139624T3 (es) 2000-02-16
NZ247307A (en) 1997-06-24
EP0564093A1 (en) 1993-10-06
HUT65849A (en) 1994-07-28
DE69327128D1 (de) 2000-01-05
GR3032373T3 (en) 2000-04-27
IL105141A (en) 1998-10-30
KR0137927B1 (ko) 1998-05-15
ATE187069T1 (de) 1999-12-15
DE69327128T2 (de) 2000-04-20
HU9300947D0 (en) 1993-06-28
KR930021203A (ko) 1993-11-22
AU660359B2 (en) 1995-06-22
HU225113B1 (en) 2006-06-28
MX9301824A (es) 1994-02-28
ZA932307B (en) 1994-09-30

Similar Documents

Publication Publication Date Title
UY24625A1 (es) Derivados de la 4-hidroxi-piperidina
DK0641325T3 (da) Inhibitorer af retroviral protease
DK0562956T3 (da) Hidtil ukendte naphthylalkylaminer, fremgangsmåde til fremstilling heraf og farmaceutiske midler, som indeholder dem
FI961739A (fi) Amiinisuoloja klavulaanihapon valmistamiseksi
SE8404019L (sv) Oftalmiska antiinflammatoriska medel
ATE77552T1 (de) Doxazosin als antiatherosklerotikum.
AR003451A1 (es) Derivados de piperazina, una composicion farmaceutica que los comprende, el uso de los mismos y un metodo para su preparacion.
DK0564093T3 (da) Hydroxylerede metabolitter og derivater af doxazosin som antiatherosklerosemidler
DK0696194T3 (da) Anvendelse af indolderivater som 5HT1-antagonister
ES2182090T3 (es) Nuevos derivados de pirrol.
ES2077473T3 (es) Nuevos compuestos tiocromanicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
DK0470431T3 (da) Anvendelse af farmaceutisk acceptable fosfomycinsalte som topisk cicatriceringsmiddel
ES2164168T3 (es) Antagonistas de receptores de fibrinogeno que tienen residuos de beta-aminoacido sustituidos y composiciones farmaceuticas que comprenden los mismos.
FI922777A0 (fi) Laitteisto telaston telavälysten säätämiseksi
DK0775692T3 (da) Guanidinomethylcyclohexancarboxylsyreesterderivater
ES2105780T3 (es) Procedimiento para la preparacion de rufloxacina y sus sales.
DK30284A (da) Pyrrolidiner
ES2159098T3 (es) Nuevos derivados de elipticina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2123038T3 (es) Nuevos derivados pirrolo-tieno-pirazinicos, su procedimiento de preparacion y composiciones farmaceuticas que los contienen.
ES2089439T3 (es) Nuevos derivados amidicos de 1-amino-octahidro-pirido-(2,1-c)-(1,4)-oxazina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
ES2157542T3 (es) Nuevos derivados de elipticina, su procedimiento de preparacion y las composiciones farmaceuticas que los contienen.
MX20102A (es) Procedimiento para la preparacion de derivados de benzopirano.
BR7000839U (pt) Disposicao construtiva aplicada a equipamento destinado a reproducao imagens
IT1273204B (it) Apparecchiatura per l'allineamento di un fascio laser di potenza con il relativo fascio laser di puntamento