DK0561882T3 - Hydroxamsyrederivater, som inhiberer lipoxygenase - Google Patents

Hydroxamsyrederivater, som inhiberer lipoxygenase

Info

Publication number
DK0561882T3
DK0561882T3 DK92900468.7T DK92900468T DK0561882T3 DK 0561882 T3 DK0561882 T3 DK 0561882T3 DK 92900468 T DK92900468 T DK 92900468T DK 0561882 T3 DK0561882 T3 DK 0561882T3
Authority
DK
Denmark
Prior art keywords
acid derivatives
hydroxamic acid
inhibit lipoxygenase
inhibit
conditions
Prior art date
Application number
DK92900468.7T
Other languages
Danish (da)
English (en)
Inventor
Kazuo Ando
Takafumi Ikeda
Masami Nakane
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0561882T3 publication Critical patent/DK0561882T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C259/00—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups
    • C07C259/04—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids
    • C07C259/06—Compounds containing carboxyl groups, an oxygen atom of a carboxyl group being replaced by a nitrogen atom, this nitrogen atom being further bound to an oxygen atom and not being part of nitro or nitroso groups without replacement of the other oxygen atom of the carboxyl group, e.g. hydroxamic acids having carbon atoms of hydroxamic groups bound to hydrogen atoms or to acyclic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C275/00—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups
    • C07C275/64—Derivatives of urea, i.e. compounds containing any of the groups, the nitrogen atoms not being part of nitro or nitroso groups having nitrogen atoms of urea groups singly-bound to oxygen atoms

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
DK92900468.7T 1990-12-11 1991-10-08 Hydroxamsyrederivater, som inhiberer lipoxygenase DK0561882T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP2415745A JPH06256285A (ja) 1990-12-11 1990-12-11 ヒドロキサム酸誘導体およびその用途

Publications (1)

Publication Number Publication Date
DK0561882T3 true DK0561882T3 (da) 1994-10-03

Family

ID=18524043

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92900468.7T DK0561882T3 (da) 1990-12-11 1991-10-08 Hydroxamsyrederivater, som inhiberer lipoxygenase

Country Status (11)

Country Link
EP (1) EP0561882B1 (de)
JP (1) JPH06256285A (de)
AT (1) ATE110714T1 (de)
CA (1) CA2094247A1 (de)
DE (1) DE69103773T2 (de)
DK (1) DK0561882T3 (de)
ES (1) ES2059204T3 (de)
FI (1) FI932654A0 (de)
IE (1) IE63704B1 (de)
PT (1) PT99729A (de)
WO (1) WO1992010469A1 (de)

Families Citing this family (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5476873A (en) * 1990-07-25 1995-12-19 Abbott Laboratories Acetylene derivatives having lipoxygenase inhibitory activity
DK0540673T3 (da) * 1990-07-25 1997-03-24 Abbott Lab Acetylen-derivater med lipoxygenaseinhiberende virkning
GB9215921D0 (en) * 1992-07-27 1992-09-09 Wellcome Found Anti-inflammatory compounds
US5288751A (en) * 1992-11-06 1994-02-22 Abbott Laboratories [(Substituted) phenyalkyl]furylalkynyl-and [substituted) phenyalkyl] thienylalkynyl-N-hydroxyurea inhibitors or leukotriene biosynthesis
US5342980A (en) * 1992-12-30 1994-08-30 American Cyanamid Company Fungicidal agents
GB9308652D0 (en) * 1993-04-27 1993-06-09 Wellcome Found Anti-inflammatory compounds
TW448144B (en) * 1993-08-19 2001-08-01 Pfizer Phenoxyphenyl cyclopentenyl hydroxyureas
JP2732504B2 (ja) * 1995-03-08 1998-03-30 農林水産省中国農業試験場長 アラキドン酸代謝活性阻害剤とその製造法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0351214A1 (de) * 1988-07-14 1990-01-17 The Wellcome Foundation Limited Entzündungshemmende Arylderivate
EP0384594B1 (de) * 1989-02-03 1993-10-27 The Wellcome Foundation Limited Entzündungshemmende Arylderivate
CA2050597A1 (en) * 1989-03-30 1990-10-01 Dee W. Brooks Urea based lipoxygenase inhibiting compounds

Also Published As

Publication number Publication date
PT99729A (pt) 1992-11-30
IE63704B1 (en) 1995-05-31
JPH06256285A (ja) 1994-09-13
EP0561882B1 (de) 1994-08-31
CA2094247A1 (en) 1992-06-13
ES2059204T3 (es) 1994-11-01
FI932654A (fi) 1993-06-10
FI932654A0 (fi) 1993-06-10
WO1992010469A1 (en) 1992-06-25
IE914284A1 (en) 1992-06-17
DE69103773D1 (de) 1994-10-06
DE69103773T2 (de) 1994-12-15
EP0561882A1 (de) 1993-09-29
ATE110714T1 (de) 1994-09-15

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