DK0557451T3 - Karakterisering af blodpladesygdomme - Google Patents

Karakterisering af blodpladesygdomme

Info

Publication number
DK0557451T3
DK0557451T3 DK92901259T DK92901259T DK0557451T3 DK 0557451 T3 DK0557451 T3 DK 0557451T3 DK 92901259 T DK92901259 T DK 92901259T DK 92901259 T DK92901259 T DK 92901259T DK 0557451 T3 DK0557451 T3 DK 0557451T3
Authority
DK
Denmark
Prior art keywords
defects
characterization
activation
ligand binding
characterizing
Prior art date
Application number
DK92901259T
Other languages
Danish (da)
English (en)
Inventor
Mark H Ginsberg
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Application granted granted Critical
Publication of DK0557451T3 publication Critical patent/DK0557451T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Pathology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Virology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Materials For Medical Uses (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Laminated Bodies (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK92901259T 1990-11-15 1991-11-15 Karakterisering af blodpladesygdomme DK0557451T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/614,723 US5196309A (en) 1990-11-15 1990-11-15 Characterization of platelet aggregation disorders
PCT/US1991/008579 WO1992008982A1 (en) 1990-11-15 1991-11-15 Characterization of platelet aggregation disorders

Publications (1)

Publication Number Publication Date
DK0557451T3 true DK0557451T3 (da) 1998-09-23

Family

ID=24462455

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92901259T DK0557451T3 (da) 1990-11-15 1991-11-15 Karakterisering af blodpladesygdomme

Country Status (13)

Country Link
US (2) US5196309A (ja)
EP (1) EP0557451B1 (ja)
JP (1) JP3186765B2 (ja)
AT (1) ATE163481T1 (ja)
AU (1) AU650312B2 (ja)
CA (1) CA2096230C (ja)
DE (1) DE69128966T2 (ja)
DK (1) DK0557451T3 (ja)
ES (1) ES2112310T3 (ja)
GR (1) GR3026510T3 (ja)
IE (1) IE62627B1 (ja)
PT (1) PT99532B (ja)
WO (1) WO1992008982A1 (ja)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5427913A (en) * 1992-12-03 1995-06-27 Alberta Cancer Board Methods for determining platelet function
US5763199A (en) * 1994-09-29 1998-06-09 Mount Sinai School Of Medicine Of The City University Of New York Platelet blockade assay
US5561047A (en) * 1994-12-13 1996-10-01 The Trustees Of The University Of Pennsylvania Method of identifying effectors of integrin activation
US6521211B1 (en) * 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US6139819A (en) 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
GB9519667D0 (en) * 1995-09-27 1995-11-29 Univ Manchester Pharmaceutical composition
EP0983509B1 (en) * 1997-05-14 2005-08-17 Biosite Diagnostics Inc. Rapid evaluation of the ratio of biological molecules
WO1998053320A1 (en) * 1997-05-20 1998-11-26 The Johns Hopkins University A novel thrombopoietin signaling defect in polycythemia vera platelets
FR2764388B1 (fr) * 1997-06-06 1999-08-27 Biocytex Nouvelle methode d'analyse des recepteurs plaquettaires gpiib/iiia
US6210904B1 (en) 1997-10-14 2001-04-03 Merck & Co., Inc. Anticoagulant test
US6040182A (en) * 1997-11-12 2000-03-21 Becton Dickinson And Company Method and materials for efficiency protein immobilization on tissue culture treated assay plates
US6063584A (en) * 1997-11-21 2000-05-16 Merck & Co., Inc. Anticoagulant test
US20030003515A1 (en) * 2000-12-05 2003-01-02 Farrell David H. Monocloral antibody-based diagnostic assay for gamma fibrinogen
US20040131500A1 (en) * 2002-01-18 2004-07-08 Chow Herbert S. Device and method for evaluating platelets
WO2005007868A2 (en) 2003-07-08 2005-01-27 Accumetrics, Inc. Controlled platelet activation to monitor therapy of adp antagonists
US20070243632A1 (en) 2003-07-08 2007-10-18 Coller Barry S Methods for measuring platelet reactivity of patients that have received drug eluting stents
JP2010261790A (ja) * 2009-05-01 2010-11-18 Takemichi Kanazawa 血管障害の素因の検査方法、及び治療法の選択方法
WO2015138916A1 (en) * 2014-03-14 2015-09-17 Yves Claude Nicolau Myo-inositol trispyrophoshate as an anti-diabetic agent
PT3259402T (pt) * 2015-01-14 2020-04-06 Sorin Dinu Dispositivo robusto para nivelar a areia em dimensões prescritas e para colocar dutos em um canal de esgoto
WO2019047042A1 (zh) * 2017-09-05 2019-03-14 深圳迈瑞生物医疗电子股份有限公司 血小板聚集样本的报警方法、血细胞分析仪及存储介质

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783330A (en) * 1984-11-15 1988-11-08 New England Medical Center Hospitals, Inc. Monoclonal antibodies to activated platelets
US4820505A (en) * 1985-04-04 1989-04-11 Scripps Clinic And Research Foundation Detection of activated platelets with antibodies to thrombospondin
US5114842A (en) * 1987-07-08 1992-05-19 The Scripps Research Institute Peptides and antibodies that inhibit platelet adhesion

Also Published As

Publication number Publication date
US5196309A (en) 1993-03-23
PT99532A (pt) 1992-09-30
DE69128966D1 (de) 1998-04-02
JP3186765B2 (ja) 2001-07-11
GR3026510T3 (en) 1998-07-31
PT99532B (pt) 1999-04-30
ES2112310T3 (es) 1998-04-01
CA2096230C (en) 2003-05-27
US5656442A (en) 1997-08-12
WO1992008982A1 (en) 1992-05-29
AU650312B2 (en) 1994-06-16
IE913975A1 (en) 1992-05-20
ATE163481T1 (de) 1998-03-15
CA2096230A1 (en) 1992-05-16
DE69128966T2 (de) 1998-06-18
EP0557451A1 (en) 1993-09-01
AU9082491A (en) 1992-06-11
IE62627B1 (en) 1995-02-22
EP0557451A4 (en) 1994-06-01
EP0557451B1 (en) 1998-02-25
JPH06504842A (ja) 1994-06-02

Similar Documents

Publication Publication Date Title
DK0557451T3 (da) Karakterisering af blodpladesygdomme
Papadimitriou et al. The complexity of immunohistochemical staining pattern of hodgkin and sternberg‐reed cells—demonstration of immunoglobulin, albumin, α1‐antichymotrypsin and lysozyme
ATE128183T1 (de) Peptide und antikörper, die die bindung von blutplättchen verhindern.
DE69129896D1 (de) Gegen cd3 gerichtete antikörper
ATE153701T1 (de) Immunchromatographischer assay und verfahren zur nutzung desselben
ATE504601T1 (de) Anti-cd3-antikörper zur verwendung zur induzierung von immunsuppression
ATE76301T1 (de) Nachweis aktivierter blutplaettchen mittels antikoerper gegen zelloberflaechenantigene.
DE69534996D1 (de) Monoklonaler antikörper gegen flt4-rezeptor-tyrosinkinase und dessen verwendung zur diagnose und therapie
ATE429449T1 (de) Anti-fas-ligand antikörper und testmethode unter verwendung derselben
ES2070488T5 (es) Procedimiento para la diagnosis de enfermedades tumorales.
DE69032112D1 (de) Verfahren zur Isolierung von fetalen Zytotrophoblastzellen
ATE121788T1 (de) Blutgerinnungsfaktor beta xiia monoklonale antikörper und immunanalyse.
Shinjo et al. Erythropoietin receptor expression on human bone marrow erythroid precursor cells by a newly‐devised quantitative flow‐cytometric assay
ES8501630A1 (es) Un metodo para detectar o vigilar el estado de una condicion patologica humana que implica proteina de tejido conjuntivo.
ATE151882T1 (de) Karzinomverwandtes haptoglobin (hpr)
CA2308604A1 (en) Antibodies against phosphorylated vasp (vasodilator-stimulated phosphoprotein), hybridoma cells for their preparation, and their use
IL123247A0 (en) Assay for the diagnosis of dementia
DE69229284D1 (de) Unterscheidung von htlv-i und htlv-ii unter verwendung von synthetischen peptiden
DE3785175D1 (de) A-assoziierte h-antigene, spezifische monoklonale antikoerper und methoden zu deren verwendung zur blutgruppenbestimmung.
Loyson et al. Immunohistochemical analysis of decalcified paraffin‐embedded human bone marrow biopsies with emphasis on MHC class I and CD34 expression
DE69111429D1 (de) Monoklonale antikörper, die einen unterschied zwischen nativproteinen und proteinen mit einer modifizierten sequenz machen.
Michalska et al. Flow cytometry crossmatch in living donor renal transplantation
TH131300B (th) ตัวแปรอิมมูโนกลูบูลินและการใช้สิ่งนั้น