GR3026510T3 - Characterization of platelet aggregation disorders - Google Patents

Characterization of platelet aggregation disorders

Info

Publication number
GR3026510T3
GR3026510T3 GR980400694T GR980400694T GR3026510T3 GR 3026510 T3 GR3026510 T3 GR 3026510T3 GR 980400694 T GR980400694 T GR 980400694T GR 980400694 T GR980400694 T GR 980400694T GR 3026510 T3 GR3026510 T3 GR 3026510T3
Authority
GR
Greece
Prior art keywords
defects
platelet aggregation
characterization
activation
ligand binding
Prior art date
Application number
GR980400694T
Other languages
English (en)
Inventor
Mark H Ginsberg
Original Assignee
Scripps Research Inst
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scripps Research Inst filed Critical Scripps Research Inst
Publication of GR3026510T3 publication Critical patent/GR3026510T3/el

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • C07K16/2848—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily against integrin beta3-subunit-containing molecules, e.g. CD41, CD51, CD61
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/28—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants
    • C07K16/2839—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against receptors, cell surface antigens or cell surface determinants against the integrin superfamily
    • G—PHYSICS
    • G01—MEASURING; TESTING
    • G01N—INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIR CHEMICAL OR PHYSICAL PROPERTIES
    • G01N33/00—Investigating or analysing materials by specific methods not covered by groups G01N1/00 - G01N31/00
    • G01N33/48—Biological material, e.g. blood, urine; Haemocytometers
    • G01N33/50—Chemical analysis of biological material, e.g. blood, urine; Testing involving biospecific ligand binding methods; Immunological testing
    • G01N33/53—Immunoassay; Biospecific binding assay; Materials therefor
    • G01N33/569—Immunoassay; Biospecific binding assay; Materials therefor for microorganisms, e.g. protozoa, bacteria, viruses
    • G01N33/56966—Animal cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/30—Immunoglobulins specific features characterized by aspects of specificity or valency
    • C07K2317/34—Identification of a linear epitope shorter than 20 amino acid residues or of a conformational epitope defined by amino acid residues
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00—Chemistry: molecular biology and microbiology
    • Y10S435/975—Kit

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Immunology (AREA)
  • Molecular Biology (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Genetics & Genomics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Cell Biology (AREA)
  • Urology & Nephrology (AREA)
  • Hematology (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Microbiology (AREA)
  • Zoology (AREA)
  • Food Science & Technology (AREA)
  • Physics & Mathematics (AREA)
  • Analytical Chemistry (AREA)
  • General Physics & Mathematics (AREA)
  • Pathology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Materials For Medical Uses (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Investigating, Analyzing Materials By Fluorescence Or Luminescence (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Sampling And Sample Adjustment (AREA)
  • Laminated Bodies (AREA)
GR980400694T 1990-11-15 1998-04-03 Characterization of platelet aggregation disorders GR3026510T3 (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US07/614,723 US5196309A (en) 1990-11-15 1990-11-15 Characterization of platelet aggregation disorders
PCT/US1991/008579 WO1992008982A1 (en) 1990-11-15 1991-11-15 Characterization of platelet aggregation disorders

Publications (1)

Publication Number Publication Date
GR3026510T3 true GR3026510T3 (en) 1998-07-31

Family

ID=24462455

Family Applications (1)

Application Number Title Priority Date Filing Date
GR980400694T GR3026510T3 (en) 1990-11-15 1998-04-03 Characterization of platelet aggregation disorders

Country Status (13)

Country Link
US (2) US5196309A (el)
EP (1) EP0557451B1 (el)
JP (1) JP3186765B2 (el)
AT (1) ATE163481T1 (el)
AU (1) AU650312B2 (el)
CA (1) CA2096230C (el)
DE (1) DE69128966T2 (el)
DK (1) DK0557451T3 (el)
ES (1) ES2112310T3 (el)
GR (1) GR3026510T3 (el)
IE (1) IE62627B1 (el)
PT (1) PT99532B (el)
WO (1) WO1992008982A1 (el)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5427913A (en) * 1992-12-03 1995-06-27 Alberta Cancer Board Methods for determining platelet function
US5763199A (en) * 1994-09-29 1998-06-09 Mount Sinai School Of Medicine Of The City University Of New York Platelet blockade assay
US5561047A (en) * 1994-12-13 1996-10-01 The Trustees Of The University Of Pennsylvania Method of identifying effectors of integrin activation
US6521211B1 (en) 1995-06-07 2003-02-18 Bristol-Myers Squibb Medical Imaging, Inc. Methods of imaging and treatment with targeted compositions
US6139819A (en) 1995-06-07 2000-10-31 Imarx Pharmaceutical Corp. Targeted contrast agents for diagnostic and therapeutic use
GB9519667D0 (en) * 1995-09-27 1995-11-29 Univ Manchester Pharmaceutical composition
CA2290582C (en) * 1997-05-14 2005-08-02 Kenneth F. Buechler Rapid evaluation of the ratio of biological molecules
US6150120A (en) * 1997-05-20 2000-11-21 The Johns Hopkins University Methods to assay a thrombopoietin signaling defect in polycythemia vera platelets
FR2764388B1 (fr) * 1997-06-06 1999-08-27 Biocytex Nouvelle methode d'analyse des recepteurs plaquettaires gpiib/iiia
US6210904B1 (en) * 1997-10-14 2001-04-03 Merck & Co., Inc. Anticoagulant test
US6040182A (en) * 1997-11-12 2000-03-21 Becton Dickinson And Company Method and materials for efficiency protein immobilization on tissue culture treated assay plates
US6063584A (en) * 1997-11-21 2000-05-16 Merck & Co., Inc. Anticoagulant test
US20030003515A1 (en) * 2000-12-05 2003-01-02 Farrell David H. Monocloral antibody-based diagnostic assay for gamma fibrinogen
US20040131500A1 (en) * 2002-01-18 2004-07-08 Chow Herbert S. Device and method for evaluating platelets
US20070243632A1 (en) 2003-07-08 2007-10-18 Coller Barry S Methods for measuring platelet reactivity of patients that have received drug eluting stents
US7790362B2 (en) 2003-07-08 2010-09-07 Accumetrics, Inc. Controlled platelet activation to monitor therapy of ADP antagonists
JP2010261790A (ja) * 2009-05-01 2010-11-18 Takemichi Kanazawa 血管障害の素因の検査方法、及び治療法の選択方法
WO2015138916A1 (en) * 2014-03-14 2015-09-17 Yves Claude Nicolau Myo-inositol trispyrophoshate as an anti-diabetic agent
WO2016114679A1 (en) * 2015-01-14 2016-07-21 Sorin Dinu Robust device for spreading sand at predetermined dimensions and for placing ducts in a sewerage channel
WO2019047042A1 (zh) * 2017-09-05 2019-03-14 深圳迈瑞生物医疗电子股份有限公司 血小板聚集样本的报警方法、血细胞分析仪及存储介质

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4783330A (en) * 1984-11-15 1988-11-08 New England Medical Center Hospitals, Inc. Monoclonal antibodies to activated platelets
US4820505A (en) * 1985-04-04 1989-04-11 Scripps Clinic And Research Foundation Detection of activated platelets with antibodies to thrombospondin
US5114842A (en) * 1987-07-08 1992-05-19 The Scripps Research Institute Peptides and antibodies that inhibit platelet adhesion

Also Published As

Publication number Publication date
EP0557451B1 (en) 1998-02-25
AU9082491A (en) 1992-06-11
DE69128966D1 (de) 1998-04-02
WO1992008982A1 (en) 1992-05-29
US5656442A (en) 1997-08-12
CA2096230C (en) 2003-05-27
ES2112310T3 (es) 1998-04-01
CA2096230A1 (en) 1992-05-16
PT99532A (pt) 1992-09-30
JPH06504842A (ja) 1994-06-02
EP0557451A4 (en) 1994-06-01
EP0557451A1 (en) 1993-09-01
DK0557451T3 (da) 1998-09-23
JP3186765B2 (ja) 2001-07-11
AU650312B2 (en) 1994-06-16
IE62627B1 (en) 1995-02-22
IE913975A1 (en) 1992-05-20
PT99532B (pt) 1999-04-30
US5196309A (en) 1993-03-23
ATE163481T1 (de) 1998-03-15
DE69128966T2 (de) 1998-06-18

Similar Documents

Publication Publication Date Title
GR3026510T3 (en) Characterization of platelet aggregation disorders
EP0326595A4 (en) Peptides and antibodies that inhibit platelet adhesion
ATE153701T1 (de) Immunchromatographischer assay und verfahren zur nutzung desselben
MY109045A (en) Mammalian receptors for interleukin 10 (il-10)
ES470723A1 (es) Un aparato para la recogida continua de fracciones sangui- neas
GB2249310B (en) Antibody preparation
DE69126142D1 (de) Verbessertes bestimmungsverfahren für liganden
Shinjo et al. Erythropoietin receptor expression on human bone marrow erythroid precursor cells by a newly‐devised quantitative flow‐cytometric assay
DE69032112T2 (de) Verfahren zur Isolierung von fetalen Zytotrophoblastzellen
GB8901859D0 (en) Diagnostic test
EP0109434A4 (en) IN VITRO DIAGNOSTICS METHODS USING MONOCLONAL ANTIBODIES AGAINST PROTEINS OF CONNECTIVE TISSUES.
IL115465A0 (en) Assay for the diagnosis of dementia
DE69229284T2 (de) Unterscheidung von htlv-i und htlv-ii unter verwendung von synthetischen peptiden
IE862325L (en) Monoclonal antibodies
DE3785175T2 (de) A-assoziierte h-antigene, spezifische monoklonale antikoerper und methoden zu deren verwendung zur blutgruppenbestimmung.
AU7407096A (en) In vitro methods for determining in vivo thrombotic events
Michalska et al. Flow cytometry crossmatch in living donor renal transplantation
Zocchi et al. Dual‐parameter flow cytometric analysis of an early lymphocyte activation antigen (CK226) and DNA content