DK0555036T3 - Antitumorpræparat og fremgangsmåde til behandling - Google Patents

Antitumorpræparat og fremgangsmåde til behandling

Info

Publication number
DK0555036T3
DK0555036T3 DK93300710T DK93300710T DK0555036T3 DK 0555036 T3 DK0555036 T3 DK 0555036T3 DK 93300710 T DK93300710 T DK 93300710T DK 93300710 T DK93300710 T DK 93300710T DK 0555036 T3 DK0555036 T3 DK 0555036T3
Authority
DK
Denmark
Prior art keywords
treatment
tumor preparation
provides
dihydrobenzofuran
dichlorophenyl
Prior art date
Application number
DK93300710T
Other languages
Danish (da)
English (en)
Inventor
Gerald Burr Grindey
William Joseph Ehlhardt
John Eldon Toth
George Bernard Boder
John Frederick Worzalla
John Lyle Zimmerman
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0555036T3 publication Critical patent/DK0555036T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Undergarments, Swaddling Clothes, Handkerchiefs Or Underwear Materials (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Furan Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK93300710T 1992-02-05 1993-02-01 Antitumorpræparat og fremgangsmåde til behandling DK0555036T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/831,604 US5254582A (en) 1992-02-05 1992-02-05 Antitumor compositions and methods

Publications (1)

Publication Number Publication Date
DK0555036T3 true DK0555036T3 (da) 1999-06-07

Family

ID=25259448

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93300710T DK0555036T3 (da) 1992-02-05 1993-02-01 Antitumorpræparat og fremgangsmåde til behandling

Country Status (25)

Country Link
US (1) US5254582A (fr)
EP (1) EP0555036B1 (fr)
JP (1) JP3210117B2 (fr)
KR (1) KR100246148B1 (fr)
CN (1) CN1044239C (fr)
AT (1) ATE170853T1 (fr)
AU (1) AU658043B2 (fr)
BR (1) BR9300469A (fr)
CA (1) CA2088719A1 (fr)
CY (1) CY2101B1 (fr)
CZ (1) CZ282753B6 (fr)
DE (1) DE69320844T2 (fr)
DK (1) DK0555036T3 (fr)
ES (1) ES2121940T3 (fr)
FI (1) FI930453A (fr)
HU (2) HU213231B (fr)
IL (1) IL104574A (fr)
MX (1) MX9300558A (fr)
MY (1) MY109640A (fr)
NO (1) NO302472B1 (fr)
NZ (1) NZ245818A (fr)
RU (1) RU2072996C1 (fr)
SG (1) SG79181A1 (fr)
YU (1) YU48915B (fr)
ZA (1) ZA93689B (fr)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5116874A (en) * 1985-09-23 1992-05-26 Eli Lilly And Company Anti-tumor method and compounds
US5529999A (en) * 1994-03-04 1996-06-25 Eli Lilly And Company Antitumor compositions and methods of treatment
AU709107B2 (en) * 1996-08-22 1999-08-19 Dong Wha Pharmaceutical Industrial Co., Ltd. Arylsulfonylimidazolone derivatives as an antitumor agent
CA2267998A1 (fr) * 1996-10-04 1998-04-09 Eli Lilly And Company Compositions antitumorales et methodes therapeutiques
US6281240B1 (en) * 1997-04-10 2001-08-28 Eli Lilly And Company Diarylsulfonylureas for use in treating secretory diarrhea
US5932407A (en) * 1997-04-30 1999-08-03 Eastman Kodak Company Color photographic element containing oxidized developer-scavenging naphtholic coupler forming wash-out dye
ES2297490T3 (es) 2003-07-23 2008-05-01 Bayer Pharmaceuticals Corporation Omega-carboxiarildifenilurea fluoro sustituida para el tratamiento y prevencion de enfermadades y afecciones.
US8772269B2 (en) 2004-09-13 2014-07-08 Eisai R&D Management Co., Ltd. Use of sulfonamide-including compounds in combination with angiogenesis inhibitors
JP5134247B2 (ja) * 2004-09-13 2013-01-30 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホンアミド含有化合物の血管新生阻害物質との併用
EP2364699A1 (fr) 2004-09-13 2011-09-14 Eisai R&D Management Co., Ltd. Utilisation conjointe d'un composé à base de sulfonamide avec un inhibiteur de l'angiogénèse
JPWO2007123274A1 (ja) 2006-04-20 2009-09-10 エーザイ・アール・アンド・ディー・マネジメント株式会社 スルホンアミド化合物の新規感受性マーカー
CN104941647B (zh) * 2015-06-18 2017-07-04 四川之江高新材料股份有限公司 合成n‑甲基吗啉的方法及所用的负载型催化剂

Family Cites Families (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3083207A (en) * 1963-03-26 Indolinesulfonylureas
US1208561A (en) * 1914-09-14 1916-12-12 Stephen E Huff Sound-box attachment for phonographs.
US3097242A (en) * 1960-06-29 1963-07-09 Olin Mathieson Hydrindene sulfonylureas
US3102121A (en) * 1961-06-29 1963-08-27 Olin Mathieson Novel cumaransulfonylureas and 2,3-dihydrothionaphthenesulfonylureas
NL295122A (fr) * 1962-04-11
US3849110A (en) * 1963-01-07 1974-11-19 Lilly Co Eli Herbicidal method employing aryl-sulfonylureas or salts thereof
US3736122A (en) * 1969-04-10 1973-05-29 C Tung Method of controlling plant growth
AU1862083A (en) * 1982-09-02 1984-03-08 Duphar International Research B.V. Tumor growth inhibitors
CA1208561A (fr) * 1984-01-19 1986-07-29 Marius S. Brouwer Compose pharmaceutique contenant de la benzoyluree
US4845128A (en) * 1984-06-27 1989-07-04 Eli Lilly And Company N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides
JPS6163671A (ja) * 1984-09-05 1986-04-01 Shionogi & Co Ltd ２，３−ジヒドロベンゾフラン−５−スルホンアミド誘導体および降圧利尿剤
GR862353B (en) * 1985-09-23 1987-01-19 Lilly Co Eli Anti-tumor method and compounds
US5116874A (en) * 1985-09-23 1992-05-26 Eli Lilly And Company Anti-tumor method and compounds
CA1331464C (fr) * 1987-05-12 1994-08-16 Eli Lilly And Company Methode et composes antitumoraux
ZA915371B (en) * 1990-07-17 1993-03-31 Lilly Co Eli Antitumor compositions and methods of treatment
US5169860A (en) * 1992-03-13 1992-12-08 Eli Lilly And Company Antitumor compositions and methods of treatment

Also Published As

Publication number Publication date
US5254582A (en) 1993-10-19
YU5893A (sh) 1996-07-24
HU213231B (en) 1997-03-28
NZ245818A (en) 1995-03-28
FI930453A (fi) 1993-08-06
IL104574A0 (en) 1993-06-10
KR930017885A (ko) 1993-09-20
JP3210117B2 (ja) 2001-09-17
MY109640A (en) 1997-03-31
JPH05306277A (ja) 1993-11-19
YU48915B (sh) 2002-11-15
MX9300558A (es) 1993-08-01
BR9300469A (pt) 1993-08-10
EP0555036A2 (fr) 1993-08-11
ATE170853T1 (de) 1998-09-15
KR100246148B1 (ko) 2000-04-01
CN1075961A (zh) 1993-09-08
CZ282753B6 (cs) 1997-09-17
EP0555036A3 (en) 1993-11-24
CZ12093A3 (en) 1993-12-15
CA2088719A1 (fr) 1993-08-06
CY2101B1 (en) 2002-04-05
IL104574A (en) 1997-02-18
RU2072996C1 (ru) 1997-02-10
CN1044239C (zh) 1999-07-21
DE69320844D1 (de) 1998-10-15
HU211561A9 (en) 1995-12-28
NO302472B1 (no) 1998-03-09
HUT63842A (en) 1993-10-28
ZA93689B (en) 1994-08-01
NO930380L (no) 1993-08-06
HU9300288D0 (en) 1993-04-28
AU3218393A (en) 1993-08-12
DE69320844T2 (de) 1999-03-04
EP0555036B1 (fr) 1998-09-09
ES2121940T3 (es) 1998-12-16
SG79181A1 (en) 2001-03-20
AU658043B2 (en) 1995-03-30
FI930453A0 (fi) 1993-02-02
NO930380D0 (no) 1993-02-03

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