DK0552137T3 - Estere af acylcarnitiner med langkædede alifatiske alkoholer og farmaceutiske præparater indeholdende sådanne med antibakteriel aktivitet - Google Patents

Estere af acylcarnitiner med langkædede alifatiske alkoholer og farmaceutiske præparater indeholdende sådanne med antibakteriel aktivitet

Info

Publication number
DK0552137T3
DK0552137T3 DK93830009.2T DK93830009T DK0552137T3 DK 0552137 T3 DK0552137 T3 DK 0552137T3 DK 93830009 T DK93830009 T DK 93830009T DK 0552137 T3 DK0552137 T3 DK 0552137T3
Authority
DK
Denmark
Prior art keywords
esters
antibacterial activity
acylcarnitines
long chain
aliphatic alcohols
Prior art date
Application number
DK93830009.2T
Other languages
English (en)
Inventor
Domenico Misiti
Maria Ornella Tinti
Mose Santaniello
Piero Foresta
Original Assignee
Sigma Tau Ind Farmaceuti
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sigma Tau Ind Farmaceuti filed Critical Sigma Tau Ind Farmaceuti
Application granted granted Critical
Publication of DK0552137T3 publication Critical patent/DK0552137T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C225/00—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones
    • C07C225/02—Compounds containing amino groups and doubly—bound oxygen atoms bound to the same carbon skeleton, at least one of the doubly—bound oxygen atoms not being part of a —CHO group, e.g. amino ketones having amino groups bound to acyclic carbon atoms of the carbon skeleton
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C229/00—Compounds containing amino and carboxyl groups bound to the same carbon skeleton
    • C07C229/02—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton
    • C07C229/04—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C229/22—Compounds containing amino and carboxyl groups bound to the same carbon skeleton having amino and carboxyl groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being acyclic and saturated the carbon skeleton being further substituted by oxygen atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Communicable Diseases (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK93830009.2T 1992-01-16 1993-01-15 Estere af acylcarnitiner med langkædede alifatiske alkoholer og farmaceutiske præparater indeholdende sådanne med antibakteriel aktivitet DK0552137T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
ITRM920027A IT1254135B (it) 1992-01-16 1992-01-16 Esteri di acil carnitine con alcooli alifatici a lunga catena e composizioni farmaceutiche che li contengono, ad attivita' antibatterica.

Publications (1)

Publication Number Publication Date
DK0552137T3 true DK0552137T3 (da) 1996-11-18

Family

ID=11400572

Family Applications (1)

Application Number Title Priority Date Filing Date
DK93830009.2T DK0552137T3 (da) 1992-01-16 1993-01-15 Estere af acylcarnitiner med langkædede alifatiske alkoholer og farmaceutiske præparater indeholdende sådanne med antibakteriel aktivitet

Country Status (13)

Country Link
US (2) US5498632A (da)
EP (1) EP0552137B1 (da)
JP (1) JP3294653B2 (da)
KR (1) KR100251888B1 (da)
AT (1) ATE144492T1 (da)
CA (1) CA2087085C (da)
DE (1) DE69305540T2 (da)
DK (1) DK0552137T3 (da)
ES (1) ES2093395T3 (da)
GR (1) GR3021479T3 (da)
HK (1) HK1005724A1 (da)
IT (1) IT1254135B (da)
ZA (1) ZA93162B (da)

Families Citing this family (17)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1261828B (it) 1993-07-14 1996-06-03 Sigma Tau Ind Farmaceuti Esteri di acil l-carnitine e composizioni farmaceutiche che li contengono per il trattamento dello shock endotossico.
US5741816A (en) * 1994-06-20 1998-04-21 Tanabe Seiyaku Co., Ltd. Hair-growth agent
IT1274157B (it) * 1994-09-08 1997-07-15 Avantgarde Spa "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee"
IT1274156B (it) * 1994-09-08 1997-07-15 Avantgarde Spa "sale della l-carnitina e composizioni farmaceutiche che lo contengonoper il trattamento di affezioni cutanee"
JPH08133971A (ja) * 1994-09-16 1996-05-28 Toyama Chem Co Ltd 抗ヘリコバクター剤
IT1283955B1 (it) * 1996-03-20 1998-05-07 Sigma Tau Ind Farmaceuti Bis alcanoil esteri della carnitina ad attivita' antibatterica, antimicotica ed antiprotozoaria.
KR100513996B1 (ko) * 1996-11-21 2005-12-07 아지노모토 가부시키가이샤 연속발효에의한l-글루탐산의제조방법
US6403124B1 (en) * 1997-04-16 2002-06-11 Sigma-Tau Industrie Farmaceutiche Riunite S.P.A. Storage and maintenance of blood products including red blood cells and platelets
DK2286794T3 (da) 2003-10-15 2016-07-25 Syncore Biotechnology Co Ltd Anvendelse af kationiske liposomer, som omfatter paclitaxel
CA2584188C (en) * 2003-10-16 2014-03-18 Techcom Group, Llc Reduced digestible carbohydrate food having reduced blood glucose response
US20050232911A1 (en) * 2004-04-19 2005-10-20 Schreiber Brian D Prevention and treatment of metabolic abnormalities associated with excess intramyocellular lipid
CA2601067A1 (en) 2005-05-04 2006-11-09 Medigene Ag Method of administering a cationic liposomal preparation comprising paclitaxel
ES2609388T3 (es) 2006-03-22 2017-04-20 Syncore Biotechnology Co., Ltd Tratamiento del cáncer de mama triple negativo a receptores
EP2394640A1 (en) 2010-05-21 2011-12-14 MediGene AG Improved liposomal formulations of lipophilic compounds
EP2575896A2 (en) 2010-05-26 2013-04-10 Erik Reimhult Magnetically responsive membrane structures
DK2825157T3 (da) 2012-03-16 2019-01-02 Merck Patent Gmbh Aminosyrelipider
KR20200036033A (ko) 2012-03-16 2020-04-06 메르크 파텐트 게엠베하 표적화 아미노산 지질

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH596147A5 (da) * 1974-09-25 1978-02-28 Lonza Ag
CH588443A5 (da) * 1974-09-25 1977-06-15 Lonza Ag
IT1116037B (it) * 1979-04-23 1986-02-10 Sigma Tau Ind Farmaceuti Esteri e ammidi di acil carnitine loro procedimenti di preparazione e loro uso terapeutico
IT1147079B (it) * 1980-05-30 1986-11-19 Sigma Tau Ind Farmacuetiche Ri Esteri di alcossi-acil derivati della carnitina procedimento per la loro preparatione e composizioni farmaceutiche che li contengono
IT1170861B (it) * 1981-03-31 1987-06-03 Sigma Tau Ind Farmaceuti Ester di mercaptoacil-carnitine procedimento per la loro preparazione e loro uso terapeutico
IT1191945B (it) * 1986-06-04 1988-03-31 Avantgarde Spa N-alchilammidi della d(+)-carnitina dotate di attivita' antibatterica,procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono
IT1235494B (it) * 1987-12-02 1992-09-04 Avantgarde Spa N-alchilammidi della dl e l(-)carnitina dotate di attivita' antibatterica, procedimento per la loro preparazione e composizioni farmaceutiche e cosmetiche che le contengono
IT1231751B (it) * 1989-04-12 1991-12-21 Sigma Tau Ind Farmaceuti Procedimento per la produzione di r(+) amminocarnitina e s(-) amminocarnitina
IT1231944B (it) * 1989-05-05 1992-01-16 Sigma Tau Ind Farmaceuti Composizione farmaceutica per il trattamento di protozoosi, particolarmente della tripasonomiasi comprendente d-carnitina o un alcanoilderivato della d-carnitina
IT1240775B (it) * 1990-02-23 1993-12-17 Sigma Tau Ind Farmaceuti Esteri della l-carnitina e di acil-l-carnitine con l'acido beta-idrossibutirrico e composizioni farmaceutiche che li contengono per la inibizione della degenerazione neuronale, della proteolisi epatica e nel trattamento del coma.

Also Published As

Publication number Publication date
ZA93162B (en) 1993-09-30
EP0552137B1 (en) 1996-10-23
KR930016391A (ko) 1993-08-26
DE69305540T2 (de) 1997-03-06
CA2087085A1 (en) 1993-07-17
ATE144492T1 (de) 1996-11-15
JPH05339218A (ja) 1993-12-21
JP3294653B2 (ja) 2002-06-24
CA2087085C (en) 2003-12-16
DE69305540D1 (de) 1996-11-28
KR100251888B1 (ko) 2000-05-01
HK1005724A1 (en) 1999-01-22
ES2093395T3 (es) 1996-12-16
US5498632A (en) 1996-03-12
ITRM920027A1 (it) 1993-07-16
IT1254135B (it) 1995-09-08
GR3021479T3 (en) 1997-01-31
EP0552137A2 (en) 1993-07-21
ITRM920027A0 (it) 1992-01-16
EP0552137A3 (en) 1993-10-20
US5498633A (en) 1996-03-12

Similar Documents

Publication Publication Date Title
DK0552137T3 (da) Estere af acylcarnitiner med langkædede alifatiske alkoholer og farmaceutiske præparater indeholdende sådanne med antibakteriel aktivitet
GR3032311T3 (en) Stilbene derivatives and pharmaceutical compositions containing them
PT90251A (pt) Processo de preparacao de esteres de tetralina de fenois ou de acidos benzoicos e de composicoes farmaceuticas que os contem
OA09039A (fr) Acides 3-alcenyl-1-azabicyclo(3.2.0)hep-2-ene-2carboxyliques
CA2126327A1 (en) Amidino derivatives and their use as nitric oxide synthase inhibitors
FI921522A (fi) Pyrazolopyridinfoerening och foerfarande foer dess framstaellning
ZA911728B (en) Benzisothiazolinone-1-dioxide derivatives as elastase inhibitors
DE3888415D1 (de) Salpetersäureester-Derivate.
DE69313325T2 (de) Ester von L-Carnitin und Acyl-L-Carnitin, mit entspannender Wirkung, selektiv auf den Gastrointestinaltrakt und sie enthaltende pharmazeutische Zusammensetzungen
DK0514357T3 (da) Anvendelse af estere af acyl-L-carnitiner med gamma-hydroxysmørsyre til fremstilling af farmaceutiske præparater til behandling af hepatopatier
NZ334119A (en) Use of pentynoic acid derivatives as neurotrophic and antiproliferative agents
NZ214640A (en) Trienamide derivatives and pharmaceutical compositions having anti-inflammatory and analgesic activity
NO940006L (no) Aminosyrederivater