DK0543659T3 - Malatoninderivater og kombinationer med antiøstrogene forbindelser til behandling af brystcarcinom hos pattedyr - Google Patents

Malatoninderivater og kombinationer med antiøstrogene forbindelser til behandling af brystcarcinom hos pattedyr

Info

Publication number
DK0543659T3
DK0543659T3 DK92310615.7T DK92310615T DK0543659T3 DK 0543659 T3 DK0543659 T3 DK 0543659T3 DK 92310615 T DK92310615 T DK 92310615T DK 0543659 T3 DK0543659 T3 DK 0543659T3
Authority
DK
Denmark
Prior art keywords
derivatives
breast carcinoma
malatonin
combinations
treatment
Prior art date
Application number
DK92310615.7T
Other languages
Danish (da)
English (en)
Inventor
Michael Edward Flaugh
James Allen Clemens
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Application granted granted Critical
Publication of DK0543659T3 publication Critical patent/DK0543659T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
    • A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Epidemiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Indole Compounds (AREA)
DK92310615.7T 1991-11-21 1992-11-20 Malatoninderivater og kombinationer med antiøstrogene forbindelser til behandling af brystcarcinom hos pattedyr DK0543659T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/796,108 US5196435A (en) 1991-11-21 1991-11-21 Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma

Publications (1)

Publication Number Publication Date
DK0543659T3 true DK0543659T3 (da) 1995-07-17

Family

ID=25167321

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92310615.7T DK0543659T3 (da) 1991-11-21 1992-11-20 Malatoninderivater og kombinationer med antiøstrogene forbindelser til behandling af brystcarcinom hos pattedyr

Country Status (8)

Country Link
US (1) US5196435A (ja)
EP (1) EP0543659B1 (ja)
JP (1) JPH05221861A (ja)
AT (1) ATE122232T1 (ja)
CA (1) CA2083359A1 (ja)
DE (1) DE69202441T2 (ja)
DK (1) DK0543659T3 (ja)
ES (1) ES2072102T3 (ja)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
ATE141051T1 (de) * 1992-04-07 1996-08-15 Neurim Pharma 1991 Verwendung von melatonin zur herstellung eines arzneimittels zur behandlung der gutartigen prostatahyperplasie
US5441563A (en) * 1993-07-06 1995-08-15 Armstrong World Industries, Inc. Highly insoluble azole embossing inhibitor and the use thereof
US5654325A (en) * 1993-11-18 1997-08-05 Eli Lilly And Company Melatonin derivatives for use in treating sleep disorders
US6180657B1 (en) 1993-11-18 2001-01-30 Eli Lilly And Company Melatonin derivatives for use in treating desynchronization disorders
US5763471A (en) * 1994-04-07 1998-06-09 Cemaf Melatoninergic agonist spiro indolepyrrolidine! derivatives, process for their preparation and their use as medicinal products
US5589482A (en) * 1994-12-14 1996-12-31 Pfizer Inc. Benzo-thiophene estrogen agonists to treat prostatic hyperplasia
EP0748627A3 (en) * 1995-06-14 1997-05-21 Lilly Co Eli Melatonin agonists for the treatment of benign forms of hyperplasia of the prostate
US5792785A (en) * 1995-11-24 1998-08-11 Equitech Laboratories, Inc. Method for enhancing pregnancy success in an animal
US6403631B1 (en) 1995-11-24 2002-06-11 Equitech Laboratories, Inc. Method and compositions for enhancing pregnancy success in an animal
FR2787447B1 (fr) * 1998-12-18 2001-03-23 Centre Nat Rech Scient Nouveaux derives de melatonine et medicament comprenant de tels derives
ATE301129T1 (de) 1999-05-04 2005-08-15 Strakan Int Ltd Androgen glykoside und die androgenische aktivität davon
TW593256B (en) 1999-11-16 2004-06-21 Hormos Medical Oy Ltd Triphenylalkene derivatives and their use as selective estrogen receptor modulators
US6552064B2 (en) * 2000-09-19 2003-04-22 University Of Iowa Research Foundation Use of melatonin for induction of general anesthesia
US6638966B2 (en) * 2000-09-19 2003-10-28 University Of Iowa Research Foundation Use of melatonin analogues for induction of general anesthesia
US7062312B2 (en) * 2001-01-17 2006-06-13 Pediamed Pharmaceuticals, Inc. Combination and method including a visual marker for determining compliance with a medication regimen
US20040248989A1 (en) 2003-06-05 2004-12-09 Risto Santti Method for the treatment or prevention of lower urinary tract symptoms
WO2005062992A2 (en) * 2003-12-23 2005-07-14 Abraxis Bioscience, Inc Substituted melatonin derivatives, process for their preparation, and methods of use
CN101448490A (zh) * 2006-05-22 2009-06-03 霍尔莫斯医疗有限公司 治疗慢性非细菌性前列腺炎的选择性雌激素受体调节剂或者芳香酶抑制剂
EP2121553B1 (en) * 2007-02-14 2012-06-27 Hormos Medical Ltd. Method for the preparation of therapeutically valuable triphenylbutene derivatives
US7504530B2 (en) * 2007-02-14 2009-03-17 Hormos Medical Ltd. Methods for the preparation of fispemifene from ospemifene
JP6174156B2 (ja) 2012-10-19 2017-08-02 フェルミオン オサケ ユキチュア オスペミフェンの製造方法
KR101861081B1 (ko) 2015-08-05 2018-05-28 인제대학교 산학협력단 멜라토닌 유도체를 포함하는 염증성 질환, 알러지 질환 또는 암 질환 예방 또는 치료용 조성물
CN114680114B (zh) * 2022-04-27 2022-11-15 华中农业大学 褪黑素衍生物在防治植物真菌病害中的用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4133814A (en) * 1975-10-28 1979-01-09 Eli Lilly And Company 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents
US4230862A (en) * 1975-10-28 1980-10-28 Eli Lilly And Company Antifertility compounds
US4087444A (en) * 1976-09-08 1978-05-02 Eli Lilly And Company Amides as ovulation inhibitors
DE2860900D1 (en) * 1977-08-22 1981-11-05 Ici Plc Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them
US4418068A (en) * 1981-04-03 1983-11-29 Eli Lilly And Company Antiestrogenic and antiandrugenic benzothiophenes
US4543360A (en) * 1981-09-10 1985-09-24 Degussa Aktiengesellschaft 2-(Hydroxy-phenyl)-indoles and process for their production
US4614807A (en) * 1984-10-04 1986-09-30 Eli Lilly And Company 6,7-dihalomelatonins
ZA88498B (en) * 1987-02-02 1989-10-25 Lilly Co Eli Alkylmelatonins
US4997845A (en) * 1987-02-02 1991-03-05 Eli Lilly And Company β-alkylmelatonins as ovulation inhibitors
US4855305A (en) * 1987-03-23 1989-08-08 Applied Medical Research Compositions and methods of effecting contraception utilizing melatonin
DE3821148A1 (de) * 1988-06-23 1989-12-28 Erwin Von Dr Angerer Aminoalkylindole, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate

Also Published As

Publication number Publication date
DE69202441T2 (de) 1995-10-26
JPH05221861A (ja) 1993-08-31
DE69202441D1 (de) 1995-06-14
CA2083359A1 (en) 1993-05-22
EP0543659B1 (en) 1995-05-10
ATE122232T1 (de) 1995-05-15
ES2072102T3 (es) 1995-07-01
US5196435A (en) 1993-03-23
EP0543659A1 (en) 1993-05-26

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