DK0543659T3 - Malatoninderivater og kombinationer med antiøstrogene forbindelser til behandling af brystcarcinom hos pattedyr - Google Patents
Malatoninderivater og kombinationer med antiøstrogene forbindelser til behandling af brystcarcinom hos pattedyrInfo
- Publication number
- DK0543659T3 DK0543659T3 DK92310615.7T DK92310615T DK0543659T3 DK 0543659 T3 DK0543659 T3 DK 0543659T3 DK 92310615 T DK92310615 T DK 92310615T DK 0543659 T3 DK0543659 T3 DK 0543659T3
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- breast carcinoma
- malatonin
- combinations
- treatment
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/40—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with one nitrogen as the only ring hetero atom, e.g. sulpiride, succinimide, tolmetin, buflomedil
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US07/796,108 US5196435A (en) | 1991-11-21 | 1991-11-21 | Melatonin derivatives and combinations with antiestrogen compounds for treating mammalian breast carcinoma |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0543659T3 true DK0543659T3 (da) | 1995-07-17 |
Family
ID=25167321
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK92310615.7T DK0543659T3 (da) | 1991-11-21 | 1992-11-20 | Malatoninderivater og kombinationer med antiøstrogene forbindelser til behandling af brystcarcinom hos pattedyr |
Country Status (8)
Country | Link |
---|---|
US (1) | US5196435A (da) |
EP (1) | EP0543659B1 (da) |
JP (1) | JPH05221861A (da) |
AT (1) | ATE122232T1 (da) |
CA (1) | CA2083359A1 (da) |
DE (1) | DE69202441T2 (da) |
DK (1) | DK0543659T3 (da) |
ES (1) | ES2072102T3 (da) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
ATE141051T1 (de) * | 1992-04-07 | 1996-08-15 | Neurim Pharma 1991 | Verwendung von melatonin zur herstellung eines arzneimittels zur behandlung der gutartigen prostatahyperplasie |
US5441563A (en) * | 1993-07-06 | 1995-08-15 | Armstrong World Industries, Inc. | Highly insoluble azole embossing inhibitor and the use thereof |
US6180657B1 (en) | 1993-11-18 | 2001-01-30 | Eli Lilly And Company | Melatonin derivatives for use in treating desynchronization disorders |
US5654325A (en) * | 1993-11-18 | 1997-08-05 | Eli Lilly And Company | Melatonin derivatives for use in treating sleep disorders |
AU2310895A (en) * | 1994-04-07 | 1995-10-30 | Cemaf | Novel spiro{indole-pyrrolidine} derivatives as melatoninergic agonists, method for preparing same and use thereofas a drug |
US5589482A (en) * | 1994-12-14 | 1996-12-31 | Pfizer Inc. | Benzo-thiophene estrogen agonists to treat prostatic hyperplasia |
EP0748627A3 (en) * | 1995-06-14 | 1997-05-21 | Lilly Co Eli | Melatonin agonists for the treatment of benign forms of hyperplasia of the prostate |
US5792785A (en) * | 1995-11-24 | 1998-08-11 | Equitech Laboratories, Inc. | Method for enhancing pregnancy success in an animal |
US6403631B1 (en) | 1995-11-24 | 2002-06-11 | Equitech Laboratories, Inc. | Method and compositions for enhancing pregnancy success in an animal |
FR2787447B1 (fr) * | 1998-12-18 | 2001-03-23 | Centre Nat Rech Scient | Nouveaux derives de melatonine et medicament comprenant de tels derives |
PT1175433E (pt) | 1999-05-04 | 2005-11-30 | Strakan Int Ltd | Glicosidos androgenos e sua actividade androgenica |
TW593256B (en) | 1999-11-16 | 2004-06-21 | Hormos Medical Oy Ltd | Triphenylalkene derivatives and their use as selective estrogen receptor modulators |
US6638966B2 (en) * | 2000-09-19 | 2003-10-28 | University Of Iowa Research Foundation | Use of melatonin analogues for induction of general anesthesia |
US6552064B2 (en) * | 2000-09-19 | 2003-04-22 | University Of Iowa Research Foundation | Use of melatonin for induction of general anesthesia |
US7062312B2 (en) * | 2001-01-17 | 2006-06-13 | Pediamed Pharmaceuticals, Inc. | Combination and method including a visual marker for determining compliance with a medication regimen |
US20040248989A1 (en) | 2003-06-05 | 2004-12-09 | Risto Santti | Method for the treatment or prevention of lower urinary tract symptoms |
WO2005062992A2 (en) * | 2003-12-23 | 2005-07-14 | Abraxis Bioscience, Inc | Substituted melatonin derivatives, process for their preparation, and methods of use |
KR101505884B1 (ko) * | 2006-05-22 | 2015-03-25 | 호르모스 메디칼 리미티드 | 만성 비세균성 전립선염 치료용 선택적 에스트로겐 수용체 조절제 또는 아로마타아제 저해제 |
WO2008099060A2 (en) * | 2007-02-14 | 2008-08-21 | Hormos Medical Ltd | Methods for the preparation of fispemifene from ospemifene |
CN101636372B (zh) * | 2007-02-14 | 2013-03-27 | 霍尔莫斯医疗有限公司 | 有治疗价值的三苯基丁烯衍生物的制备方法 |
WO2014060639A1 (en) | 2012-10-19 | 2014-04-24 | Fermion Oy | A process for the preparation of ospemifene |
KR101861081B1 (ko) * | 2015-08-05 | 2018-05-28 | 인제대학교 산학협력단 | 멜라토닌 유도체를 포함하는 염증성 질환, 알러지 질환 또는 암 질환 예방 또는 치료용 조성물 |
CN114680114B (zh) * | 2022-04-27 | 2022-11-15 | 华中农业大学 | 褪黑素衍生物在防治植物真菌病害中的用途 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4133814A (en) * | 1975-10-28 | 1979-01-09 | Eli Lilly And Company | 2-Phenyl-3-aroylbenzothiophenes useful as antifertility agents |
US4230862A (en) * | 1975-10-28 | 1980-10-28 | Eli Lilly And Company | Antifertility compounds |
US4087444A (en) * | 1976-09-08 | 1978-05-02 | Eli Lilly And Company | Amides as ovulation inhibitors |
EP0002097B1 (en) * | 1977-08-22 | 1981-08-05 | Imperial Chemical Industries Plc | Triphenylalkene derivatives, process for their preparation and pharmaceutical compositions containing them |
US4418068A (en) * | 1981-04-03 | 1983-11-29 | Eli Lilly And Company | Antiestrogenic and antiandrugenic benzothiophenes |
US4543360A (en) * | 1981-09-10 | 1985-09-24 | Degussa Aktiengesellschaft | 2-(Hydroxy-phenyl)-indoles and process for their production |
US4614807A (en) * | 1984-10-04 | 1986-09-30 | Eli Lilly And Company | 6,7-dihalomelatonins |
US4997845A (en) * | 1987-02-02 | 1991-03-05 | Eli Lilly And Company | β-alkylmelatonins as ovulation inhibitors |
CA1299174C (en) * | 1987-02-02 | 1992-04-21 | Michael Edward Flaugh | Alkylmelatonins |
US4855305A (en) * | 1987-03-23 | 1989-08-08 | Applied Medical Research | Compositions and methods of effecting contraception utilizing melatonin |
DE3821148A1 (de) * | 1988-06-23 | 1989-12-28 | Erwin Von Dr Angerer | Aminoalkylindole, verfahren zu deren herstellung und diese enthaltende pharmazeutische praeparate |
-
1991
- 1991-11-21 US US07/796,108 patent/US5196435A/en not_active Expired - Fee Related
-
1992
- 1992-11-19 CA CA002083359A patent/CA2083359A1/en not_active Abandoned
- 1992-11-20 DE DE69202441T patent/DE69202441T2/de not_active Expired - Fee Related
- 1992-11-20 DK DK92310615.7T patent/DK0543659T3/da active
- 1992-11-20 AT AT92310615T patent/ATE122232T1/de not_active IP Right Cessation
- 1992-11-20 ES ES92310615T patent/ES2072102T3/es not_active Expired - Lifetime
- 1992-11-20 EP EP92310615A patent/EP0543659B1/en not_active Expired - Lifetime
- 1992-11-20 JP JP4311815A patent/JPH05221861A/ja active Pending
Also Published As
Publication number | Publication date |
---|---|
ATE122232T1 (de) | 1995-05-15 |
DE69202441T2 (de) | 1995-10-26 |
DE69202441D1 (de) | 1995-06-14 |
CA2083359A1 (en) | 1993-05-22 |
ES2072102T3 (es) | 1995-07-01 |
JPH05221861A (ja) | 1993-08-31 |
US5196435A (en) | 1993-03-23 |
EP0543659B1 (en) | 1995-05-10 |
EP0543659A1 (en) | 1993-05-26 |
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