DK0530447T3 - Fremgangsmåde til rensning af IgG-monoklonale antistoffer - Google Patents

Fremgangsmåde til rensning af IgG-monoklonale antistoffer

Info

Publication number
DK0530447T3
DK0530447T3 DK92108912.4T DK92108912T DK0530447T3 DK 0530447 T3 DK0530447 T3 DK 0530447T3 DK 92108912 T DK92108912 T DK 92108912T DK 0530447 T3 DK0530447 T3 DK 0530447T3
Authority
DK
Denmark
Prior art keywords
monoclonal antibodies
igg monoclonal
purifying igg
purifying
immunotherapy
Prior art date
Application number
DK92108912.4T
Other languages
Danish (da)
English (en)
Inventor
Norbert Dr Kothe
Dieter Dr Rudnick
Ulf Dr Bethke
Michael Dr Kloft
Detlef Dr Rohm
Original Assignee
Biotest Pharma Gmbh
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Biotest Pharma Gmbh filed Critical Biotest Pharma Gmbh
Application granted granted Critical
Publication of DK0530447T3 publication Critical patent/DK0530447T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/06—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies from serum
    • C07K16/065—Purification, fragmentation

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
DK92108912.4T 1991-06-08 1992-05-27 Fremgangsmåde til rensning af IgG-monoklonale antistoffer DK0530447T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4118912A DE4118912C1 (fr) 1991-06-08 1991-06-08

Publications (1)

Publication Number Publication Date
DK0530447T3 true DK0530447T3 (da) 1998-01-12

Family

ID=6433511

Family Applications (1)

Application Number Title Priority Date Filing Date
DK92108912.4T DK0530447T3 (da) 1991-06-08 1992-05-27 Fremgangsmåde til rensning af IgG-monoklonale antistoffer

Country Status (7)

Country Link
EP (1) EP0530447B1 (fr)
JP (1) JP2644946B2 (fr)
AT (1) ATE159532T1 (fr)
DE (2) DE4118912C1 (fr)
DK (1) DK0530447T3 (fr)
ES (1) ES2108059T3 (fr)
GR (1) GR3025603T3 (fr)

Families Citing this family (23)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2706466B1 (fr) * 1993-06-14 1995-08-25 Aetsrn Concentré d'immunoglobulines G à usage thérapeutique et procédé de production dudit concentré.
IL121900A (en) * 1997-10-07 2001-12-23 Omrix Biopharmaceuticals Ltd A method for the purification of immunoglobulins
ES2527915T3 (es) 1998-06-09 2015-02-02 Csl Behring Ag Producto de inmunoglobulina G (IgG) líquido
IL140155A (en) 1998-06-09 2005-12-18 Statens Seruminstitut Process for producing immunoglobulins for intravenous administration and other immunoglobulin products
SE0001128D0 (sv) * 2000-03-30 2000-03-30 Amersham Pharm Biotech Ab A method of producing IgG
WO2004087761A1 (fr) * 2003-03-31 2004-10-14 Kirin Beer Kabushiki Kaisha Purification d'un anticorps monoclonal humain et d'un anticorps polyclonal humain
EP1532983A1 (fr) 2003-11-18 2005-05-25 ZLB Bioplasma AG Preparation d'immunoglobulines à stabilité élevée
TWI320788B (en) 2005-05-25 2010-02-21 Hoffmann La Roche Method for the purification of antibodies
BRPI0812288A2 (pt) 2007-06-01 2014-11-25 Hoffmann La Roche Purificação de imunoglobulina.
CL2008002054A1 (es) 2007-07-17 2009-05-29 Hoffmann La Roche Metodo para la regeneracion de una columna de cromatografia de intercambio cationico despues de la elusion de eritropoyetina monopeguilada y metodo para obtener una eritropoyetina monopeguilada, incorporando el metodo de regeneracion de la columna de intercambio cationico.
AR067537A1 (es) 2007-07-17 2009-10-14 Hoffmann La Roche Purificacion de polipeptidos pegilados
WO2009058769A1 (fr) * 2007-10-30 2009-05-07 Schering Corporation Purification d'anticorps contenant des variants hydrophobes
US9631008B2 (en) 2008-12-22 2017-04-25 Hoffmann-La Roche Inc. Immunoglobulin purification
PL2531218T3 (pl) 2010-02-04 2019-05-31 Csl Behring Ag Preparat immunoglobuliny
US20130131318A1 (en) * 2010-02-12 2013-05-23 Diderik Reinder Kremer Single unit antibody purification
EP2361636A1 (fr) 2010-02-26 2011-08-31 CSL Behring AG Préparation d'immunoglobuline et système de stockage pour préparation d'immunoglobuline
DK2616101T3 (da) 2010-09-14 2014-08-04 Hoffmann La Roche Fremgangsmåde til oprensning af pegyleret erythropoietin
EA201300524A1 (ru) * 2010-11-01 2013-08-30 ДСМ АйПи АССЕТС Б.В. Очистка антител ионообменной хроматографией в едином блоке
JP6116565B2 (ja) 2011-08-25 2017-04-19 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ 陽イオンおよび陰イオン交換クロマトグラフィー法
ES2546064T3 (es) 2011-11-22 2015-09-18 Heraeus Medical Gmbh Esterilización de monómeros polimerizables
WO2015137530A1 (fr) * 2014-03-11 2015-09-17 주식회사 녹십자홀딩스 Procédé de purification d'immunoglobuline
PL3226895T3 (pl) 2014-12-03 2020-12-28 Csl Behring Ag Produkt farmaceutyczny o zwiększonej stabilności zawierający immunoglobuliny
KR20220158870A (ko) 2016-07-15 2022-12-01 에프. 호프만-라 로슈 아게 Ｐｅｇ화 에리트로포이에틴을 정제하기 위한 방법

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4469630A (en) * 1983-11-25 1984-09-04 J. T. Baker Chemical Co. Purification of monoclonal antibodies
US4743680A (en) * 1985-02-01 1988-05-10 New York University Method for purifying antihemophilic factor
DE3640513A1 (de) * 1986-11-27 1988-06-09 Biotest Pharma Gmbh Verfahren zur herstellung eines virussicheren, lagerstabilen und intravenoes vertraeglichen immunglobulin-g-praeparates
DE3641115A1 (de) * 1986-12-02 1988-06-16 Lentia Gmbh Verfahren zur herstellung eines intravenoes anwendbaren und in fluessiger form stabilen immunglobulins
CA1323567C (fr) * 1987-10-05 1993-10-26 Gene R. Nathans Methode de purification des anticorps
US5118796A (en) * 1987-12-09 1992-06-02 Centocor, Incorporated Efficient large-scale purification of immunoglobulins and derivatives
CA2005600A1 (fr) * 1988-12-20 1990-06-20 Cal-Henrik Heldin Facteur de croissance des cellules endotheliales

Also Published As

Publication number Publication date
DE59208982D1 (de) 1997-11-27
EP0530447B1 (fr) 1997-10-22
ATE159532T1 (de) 1997-11-15
GR3025603T3 (en) 1998-03-31
EP0530447A2 (fr) 1993-03-10
ES2108059T3 (es) 1997-12-16
JP2644946B2 (ja) 1997-08-25
DE4118912C1 (fr) 1992-07-02
EP0530447A3 (en) 1993-08-18
JPH07267997A (ja) 1995-10-17

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