DK0508307T3 - Optisk aktive sekundære aminforbindelser, fremgangsmåde til fremstilling af en optisk aktiv sekundær aminforbindelse og fremgangsmåde til fremstilling af en optisk aktiv carboxylsyre ved anvendelse af denne forbindelse - Google Patents
Optisk aktive sekundære aminforbindelser, fremgangsmåde til fremstilling af en optisk aktiv sekundær aminforbindelse og fremgangsmåde til fremstilling af en optisk aktiv carboxylsyre ved anvendelse af denne forbindelseInfo
- Publication number
- DK0508307T3 DK0508307T3 DK92105682.6T DK92105682T DK0508307T3 DK 0508307 T3 DK0508307 T3 DK 0508307T3 DK 92105682 T DK92105682 T DK 92105682T DK 0508307 T3 DK0508307 T3 DK 0508307T3
- Authority
- DK
- Denmark
- Prior art keywords
- optically active
- secondary amine
- compound
- active secondary
- preparing
- Prior art date
Links
- -1 secondary amine compounds Chemical class 0.000 title 2
- 150000001732 carboxylic acid derivatives Chemical class 0.000 title 1
- 150000001875 compounds Chemical class 0.000 title 1
- 238000004519 manufacturing process Methods 0.000 title 1
- 238000000034 method Methods 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C217/00—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton
- C07C217/54—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C217/56—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms
- C07C217/58—Compounds containing amino and etherified hydroxy groups bound to the same carbon skeleton having etherified hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by singly-bound oxygen atoms with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/02—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton
- C07C215/04—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated
- C07C215/06—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic
- C07C215/16—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups and amino groups bound to acyclic carbon atoms of the same carbon skeleton the carbon skeleton being saturated and acyclic the nitrogen atom of the amino group being further bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07B—GENERAL METHODS OF ORGANIC CHEMISTRY; APPARATUS THEREFOR
- C07B57/00—Separation of optically-active compounds
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C215/00—Compounds containing amino and hydroxy groups bound to the same carbon skeleton
- C07C215/46—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton
- C07C215/48—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups
- C07C215/50—Compounds containing amino and hydroxy groups bound to the same carbon skeleton having hydroxy groups bound to carbon atoms of at least one six-membered aromatic ring and amino groups bound to acyclic carbon atoms or to carbon atoms of rings other than six-membered aromatic rings of the same carbon skeleton with amino groups linked to the six-membered aromatic ring, or to the condensed ring system containing that ring, by carbon chains not further substituted by hydroxy groups with amino groups and the six-membered aromatic ring, or the condensed ring system containing that ring, bound to the same carbon atom of the carbon chain
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C251/00—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton
- C07C251/02—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups
- C07C251/24—Compounds containing nitrogen atoms doubly-bound to a carbon skeleton containing imino groups having carbon atoms of imino groups bound to carbon atoms of six-membered aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C2601/00—Systems containing only non-condensed rings
- C07C2601/12—Systems containing only non-condensed rings with a six-membered ring
- C07C2601/14—The ring being saturated
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP7509691 | 1991-04-08 | ||
JP31249091 | 1991-11-27 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0508307T3 true DK0508307T3 (da) | 1995-12-27 |
Family
ID=26416239
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK92105682.6T DK0508307T3 (da) | 1991-04-08 | 1992-04-02 | Optisk aktive sekundære aminforbindelser, fremgangsmåde til fremstilling af en optisk aktiv sekundær aminforbindelse og fremgangsmåde til fremstilling af en optisk aktiv carboxylsyre ved anvendelse af denne forbindelse |
Country Status (8)
Country | Link |
---|---|
US (2) | US5298660A (ko) |
EP (1) | EP0508307B1 (ko) |
JP (1) | JP3031048B2 (ko) |
KR (1) | KR100220266B1 (ko) |
CA (1) | CA2065476C (ko) |
DE (1) | DE69206306T2 (ko) |
DK (1) | DK0508307T3 (ko) |
HU (1) | HU214741B (ko) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6313146B1 (en) | 1991-08-23 | 2001-11-06 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US6001884A (en) * | 1991-08-23 | 1999-12-14 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
CA2173747C (en) * | 1991-08-23 | 2006-05-23 | Edward F. Nemeth | Calcium receptor-active arylalkyl amines |
US6031003A (en) * | 1991-08-23 | 2000-02-29 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US5858684A (en) * | 1991-08-23 | 1999-01-12 | The Brigham And Women's Hospital, Inc. | Method of screening calcium receptor-active molecules |
US6011068A (en) * | 1991-08-23 | 2000-01-04 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
US5763569A (en) * | 1991-08-23 | 1998-06-09 | The Brigham And Women's Hospital, Inc | Calcium receptor-active molecules |
US5688938A (en) * | 1991-08-23 | 1997-11-18 | The Brigham & Women's Hospital, Inc. | Calcium receptor-active molecules |
US5962314A (en) * | 1993-02-23 | 1999-10-05 | Nps Pharmaceuticals, Inc. | Calcium receptor-active molecules |
CN1312116C (zh) * | 1994-10-21 | 2007-04-25 | Nps药物有限公司 | 钙受体活性化合物 |
CA2172946C (en) * | 1995-03-30 | 2008-01-22 | Koji Hagiya | N-(.alpha.-alkylbenzylidene)-.alpha.-phenylalkylamine, its use and process for producing the same and process for producing intermediate |
US5677469A (en) * | 1995-05-18 | 1997-10-14 | Sepracor, Inc. | Process for resolving chiral acids with 1-aminoindan-2-ols |
DK0907631T3 (da) | 1996-05-01 | 2003-09-22 | Nps Pharma Inc | Uorganiske ionreceptoraktive forbindelser |
DE69906607T2 (de) * | 1998-01-29 | 2003-12-18 | Sumitomo Chemical Co | Verfahren zur Herstellung von optisch aktiven Chrysanthemumsäure |
JP4576642B2 (ja) * | 1998-01-29 | 2010-11-10 | 住友化学株式会社 | 光学活性な菊酸の製造方法 |
EP2360160B1 (en) * | 1999-09-08 | 2013-07-24 | Daiichi Sankyo Company, Limited | Intermediates and their use for producing benzoxazine derivative |
EP1284729A4 (en) * | 2000-04-13 | 2007-12-19 | Mayo Foundation | REDUCTION AGENTS OF A (BETA) 42 |
CA2512342A1 (en) * | 2003-01-03 | 2004-07-22 | Council Of Scientific And Industrial Research | Process for preparing (+)-2-(4-chlorophenyl)-3-methyl butanoic acid |
WO2004071431A2 (en) * | 2003-02-05 | 2004-08-26 | Myriad Genetics, Inc. | Method and composition for treating neurodegenerative disorders |
KR20060040676A (ko) * | 2003-07-11 | 2006-05-10 | 미리어드 제네틱스, 인크. | 알츠하이머병을 치료하기 위한 약제학적 방법, 투약 방법및 제형 |
US20070293538A1 (en) * | 2004-04-13 | 2007-12-20 | Myriad Genetics, Incorporated | Pharmaceutical Composition And Methods For Treating Neurodegenerative Disorders |
US20050252144A1 (en) * | 2004-04-29 | 2005-11-17 | Macdonald Robert A | Veneers for walls, retaining walls and the like |
BRPI0514303A (pt) * | 2004-08-11 | 2008-06-10 | Myriad Genetics Inc | composição farmacêutica e método para tratar distúrbios neurodegenerativos |
WO2006020850A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
WO2006020852A2 (en) * | 2004-08-11 | 2006-02-23 | Myriad Genetics, Inc. | Pharmaceutical composition and method for treating neurodegenerative disorders |
AU2006272760A1 (en) * | 2005-07-22 | 2007-02-01 | Myriad Genetics, Inc. | High drug load formulations and dosage forms |
US8399615B2 (en) * | 2005-08-19 | 2013-03-19 | Vertex Pharmaceuticals Incorporated | Processes and intermediates |
WO2008006099A2 (en) * | 2006-07-07 | 2008-01-10 | Myriad Genetics, Inc. | Treatment of psychiatric disorders |
CA2677125C (en) * | 2007-02-01 | 2018-07-10 | Myriad Genetics, Inc. | Drug substance preparations, pharmaceutical compositions and dosage forms |
JP5176452B2 (ja) * | 2007-09-27 | 2013-04-03 | 住友化学株式会社 | 光学活性なテトラヒドロピラニルグリシン化合物の製造方法 |
WO2010010359A2 (en) * | 2008-07-24 | 2010-01-28 | Cilpa Limited | A process for the preparation of cinacalcet and its salts |
GB201216893D0 (en) | 2012-09-21 | 2012-11-07 | Aesica Pharmaceuticals Ltd | Drug substance preparations, pharmaceutical compositions and dosage forms comprising s-(+)-flurbiprofen |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS4834736B1 (ko) * | 1969-05-14 | 1973-10-23 | ||
US3739019A (en) * | 1969-07-02 | 1973-06-12 | Sumitomo Chemical Co | Preparation of optically active trans chrysanthemic acid |
JPS5123497B2 (ko) * | 1972-01-07 | 1976-07-17 | ||
JPS49109344A (ko) * | 1973-02-27 | 1974-10-17 | ||
DE2826952A1 (de) * | 1978-06-20 | 1980-01-10 | Bayer Ag | Enantiomerentrennung von chiralen carbonsaeuren |
JPS5910724B2 (ja) * | 1979-08-24 | 1984-03-10 | 旭化成株式会社 | エチレンの連続重合法 |
US4259521A (en) * | 1979-10-09 | 1981-03-31 | American Cyanamid Company | Process for resolving DL-mandelic acid |
US4536601A (en) * | 1982-09-28 | 1985-08-20 | Dainippon Pharmaceutical Co., Ltd. | Optically active N-substituted phenylalaninols and use thereof |
JPH0667871B2 (ja) * | 1986-07-31 | 1994-08-31 | 住友化学工業株式会社 | 第一菊酸の光学分割法 |
US5011996A (en) * | 1988-07-20 | 1991-04-30 | Bayer Aktiengesellschaft | Process for the preparation of amines |
US5191112A (en) * | 1989-10-17 | 1993-03-02 | Nissan Chemical Industries, Ltd. | Process for optical resolution of (±)-2-(3-benzoyl)-phenylpropionic acid |
-
1992
- 1992-04-02 DE DE69206306T patent/DE69206306T2/de not_active Expired - Lifetime
- 1992-04-02 DK DK92105682.6T patent/DK0508307T3/da active
- 1992-04-02 EP EP92105682A patent/EP0508307B1/en not_active Expired - Lifetime
- 1992-04-03 JP JP4081993A patent/JP3031048B2/ja not_active Expired - Fee Related
- 1992-04-06 US US07/863,976 patent/US5298660A/en not_active Expired - Lifetime
- 1992-04-07 CA CA002065476A patent/CA2065476C/en not_active Expired - Lifetime
- 1992-04-08 KR KR1019920005857A patent/KR100220266B1/ko not_active IP Right Cessation
- 1992-04-08 HU HU9201186A patent/HU214741B/hu unknown
-
1993
- 1993-12-13 US US08/165,716 patent/US5510519A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
HU9201186D0 (en) | 1992-07-28 |
US5298660A (en) | 1994-03-29 |
EP0508307B1 (en) | 1995-11-29 |
EP0508307A3 (en) | 1993-02-03 |
US5510519A (en) | 1996-04-23 |
DE69206306D1 (de) | 1996-01-11 |
JPH05201938A (ja) | 1993-08-10 |
HU214741B (hu) | 1998-10-28 |
JP3031048B2 (ja) | 2000-04-10 |
EP0508307A2 (en) | 1992-10-14 |
KR100220266B1 (ko) | 1999-10-01 |
CA2065476C (en) | 2003-10-14 |
CA2065476A1 (en) | 1992-10-09 |
HUT60995A (en) | 1992-11-30 |
KR920019721A (ko) | 1992-11-19 |
DE69206306T2 (de) | 1996-06-13 |
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