DK0504307T3 - Fremgangsmåde til behandling af septisk shock - Google Patents

Fremgangsmåde til behandling af septisk shock

Info

Publication number
DK0504307T3
DK0504307T3 DK91902317.6T DK91902317T DK0504307T3 DK 0504307 T3 DK0504307 T3 DK 0504307T3 DK 91902317 T DK91902317 T DK 91902317T DK 0504307 T3 DK0504307 T3 DK 0504307T3
Authority
DK
Denmark
Prior art keywords
septic shock
treating septic
antagonist
human
treating
Prior art date
Application number
DK91902317.6T
Other languages
Danish (da)
English (en)
Inventor
John S Abrams
H Fletcher Starnes
Original Assignee
Schering Corp
H Fletcher Starnes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp, H Fletcher Starnes filed Critical Schering Corp
Application granted granted Critical
Publication of DK0504307T3 publication Critical patent/DK0504307T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244Interleukins [IL]
    • C07K16/248IL-6
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Immunology (AREA)
  • Biochemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Fertilizers (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compression-Type Refrigeration Machines With Reversible Cycles (AREA)
  • Spinning Or Twisting Of Yarns (AREA)
  • Treatment Of Sludge (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK91902317.6T 1989-12-04 1990-11-30 Fremgangsmåde til behandling af septisk shock DK0504307T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US44519289A 1989-12-04 1989-12-04

Publications (1)

Publication Number Publication Date
DK0504307T3 true DK0504307T3 (da) 1994-03-21

Family

ID=23767939

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91902317.6T DK0504307T3 (da) 1989-12-04 1990-11-30 Fremgangsmåde til behandling af septisk shock

Country Status (11)

Country Link
EP (1) EP0504307B1 (fr)
JP (1) JPH0747547B2 (fr)
AT (1) ATE100331T1 (fr)
AU (1) AU648777B2 (fr)
CA (1) CA2070424A1 (fr)
DE (1) DE69006221T2 (fr)
DK (1) DK0504307T3 (fr)
ES (1) ES2062762T3 (fr)
FI (1) FI922551A (fr)
HU (1) HUT64481A (fr)
WO (1) WO1991007986A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0672144A1 (fr) * 1992-10-20 1995-09-20 Chiron Corporation Antagonistes du recepteur d'interleukine 6
JP3525221B2 (ja) * 1993-02-17 2004-05-10 味の素株式会社 免疫抑制剤
ES2108460T3 (es) * 1993-06-03 1997-12-16 Therapeutic Antibodies Inc Fragmentos de anticuerpos en terapeutica.
DE4409513C1 (de) * 1994-02-07 1995-10-19 Knoll Ag Verwendung von anti-TNF-Antikörpern als Arzneimittel zur Behandlung von Erkrankungen mit einem erhöhten Interleukin-6 Serumspiegel
US8017121B2 (en) 1994-06-30 2011-09-13 Chugai Seiyaku Kabushika Kaisha Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
PT783893E (pt) * 1994-10-07 2012-05-24 Chugai Pharmaceutical Co Ltd Inibição do crescimento anormal das células sinoviais usando antagonistas de il-6 como componente ativo
AU730308B2 (en) * 1997-06-18 2001-03-01 Rockefeller University, The Methods for identifying antibodies and peptides useful in the treatment of septic shock and experimental arthritis and uses thereof
US8034344B2 (en) 2008-05-13 2011-10-11 Novimmune S.A. Anti-IL-6/IL-6R antibodies and methods of use thereof
US8188235B2 (en) 2008-06-18 2012-05-29 Pfizer Inc. Antibodies to IL-6 and their uses

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2598666B2 (ja) * 1987-10-19 1997-04-09 忠三 岸本 抗ヒトbcdfモノクローナル抗体
CA1341588C (fr) * 1988-01-26 2009-01-06 Michel Revel Ifn-beta2/i1-6, humain, sa purification et ses utilisations
ES2058490T3 (es) * 1988-02-02 1994-11-01 Schering Biotech Corp Metodo de reducir respuestas de inmunoglobulina e.
EP0399429A1 (fr) * 1989-05-22 1990-11-28 Toray Industries, Inc. Anticorps monoclonal contre l'interleukine-6 humaine

Also Published As

Publication number Publication date
DE69006221D1 (de) 1994-03-03
FI922551A0 (fi) 1992-06-03
ES2062762T3 (es) 1994-12-16
CA2070424A1 (fr) 1991-06-05
WO1991007986A8 (fr) 2004-04-22
JPH0747547B2 (ja) 1995-05-24
HUT64481A (en) 1994-01-28
EP0504307B1 (fr) 1994-01-19
ATE100331T1 (de) 1994-02-15
AU648777B2 (en) 1994-05-05
FI922551A (fi) 1992-06-03
EP0504307A1 (fr) 1992-09-23
DE69006221T2 (de) 1994-05-05
AU7179491A (en) 1991-06-26
WO1991007986A1 (fr) 1991-06-13
JPH05504058A (ja) 1993-07-01
HU9201859D0 (en) 1992-09-28

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