ATE100331T1 - Verfahren zur behandlung von septischem schock. - Google Patents

Verfahren zur behandlung von septischem schock.

Info

Publication number
ATE100331T1
ATE100331T1 AT91902317T AT91902317T ATE100331T1 AT E100331 T1 ATE100331 T1 AT E100331T1 AT 91902317 T AT91902317 T AT 91902317T AT 91902317 T AT91902317 T AT 91902317T AT E100331 T1 ATE100331 T1 AT E100331T1
Authority
AT
Austria
Prior art keywords
septic shock
treatment
methods
antagonist
human
Prior art date
Application number
AT91902317T
Other languages
English (en)
Inventor
H Fletcher Starnes
John S Abrams
Original Assignee
Schering Corp
H Fletcher Starnes
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp, H Fletcher Starnes filed Critical Schering Corp
Application granted granted Critical
Publication of ATE100331T1 publication Critical patent/ATE100331T1/de

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IG], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • C07K16/248—IL-6
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Molecular Biology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Communicable Diseases (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Oncology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Fertilizers (AREA)
  • Treatment Of Sludge (AREA)
  • Spinning Or Twisting Of Yarns (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • Compression-Type Refrigeration Machines With Reversible Cycles (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AT91902317T 1989-12-04 1991-06-28 Verfahren zur behandlung von septischem schock. ATE100331T1 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US44519289A 1989-12-04 1989-12-04
PCT/US1990/006872 WO1991007986A1 (en) 1989-12-04 1990-11-30 Method of treating septic shock
EP91902317A EP0504307B1 (de) 1989-12-04 1991-06-28 Verfahren zur behandlung von septischem schock

Publications (1)

Publication Number Publication Date
ATE100331T1 true ATE100331T1 (de) 1994-02-15

Family

ID=23767939

Family Applications (1)

Application Number Title Priority Date Filing Date
AT91902317T ATE100331T1 (de) 1989-12-04 1991-06-28 Verfahren zur behandlung von septischem schock.

Country Status (11)

Country Link
EP (1) EP0504307B1 (de)
JP (1) JPH0747547B2 (de)
AT (1) ATE100331T1 (de)
AU (1) AU648777B2 (de)
CA (1) CA2070424A1 (de)
DE (1) DE69006221T2 (de)
DK (1) DK0504307T3 (de)
ES (1) ES2062762T3 (de)
FI (1) FI922551A7 (de)
HU (1) HUT64481A (de)
WO (1) WO1991007986A1 (de)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU687763B2 (en) * 1992-10-20 1998-03-05 Central Laboratory Of The Netherlands Red Cross Blood Transfusion Service Interleukin-6 receptor antagonists
JP3525221B2 (ja) * 1993-02-17 2004-05-10 味の素株式会社 免疫抑制剤
FI955798A7 (fi) * 1993-06-03 1996-02-01 Therapeutic Antibodies Inc Terapeuttiset vasta-ainefrangmentit
DE4409513C1 (de) * 1994-02-07 1995-10-19 Knoll Ag Verwendung von anti-TNF-Antikörpern als Arzneimittel zur Behandlung von Erkrankungen mit einem erhöhten Interleukin-6 Serumspiegel
US8017121B2 (en) 1994-06-30 2011-09-13 Chugai Seiyaku Kabushika Kaisha Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component
PT783893E (pt) * 1994-10-07 2012-05-24 Chugai Pharmaceutical Co Ltd Inibição do crescimento anormal das células sinoviais usando antagonistas de il-6 como componente ativo
EP1001805A1 (de) * 1997-06-18 2000-05-24 The Rockefeller University Verfahren zur identifizierung von antikörpern und peptiden für die behandlung von septischen schock und experimenteller arthritis und verwendungen
MX2010012031A (es) 2008-05-13 2011-01-20 Novimmune Sa Anticuerpos anti-il-6/il-6r y metodos de uso de los mismos.
US8188235B2 (en) 2008-06-18 2012-05-29 Pfizer Inc. Antibodies to IL-6 and their uses
EP4692802A1 (de) 2023-03-31 2026-02-11 The University of Osaka Biomarker zur prognose bei septischem patienten und verwendung davon
CN119667163B (zh) * 2024-10-18 2025-12-09 中国科学技术大学 Il-1r2在鉴定对象免疫状态中的应用

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2598666B2 (ja) * 1987-10-19 1997-04-09 忠三 岸本 抗ヒトｂｃｄｆモノクローナル抗体
CA1341588C (en) * 1988-01-26 2009-01-06 Michel Revel Human ifn-beta2/i1-6, its purification and use
DE68908431T2 (de) * 1988-02-02 1993-12-23 Schering Biotech Corp Methode zur Verminderung der Immunglobulin-E-Reaktion.
EP0399429A1 (de) * 1989-05-22 1990-11-28 Toray Industries, Inc. Monoklonaler Antikörper gegen menschliches Interleukin-6

Also Published As

Publication number Publication date
DE69006221D1 (de) 1994-03-03
CA2070424A1 (en) 1991-06-05
HUT64481A (en) 1994-01-28
AU648777B2 (en) 1994-05-05
WO1991007986A8 (en) 2004-04-22
HU9201859D0 (en) 1992-09-28
JPH05504058A (ja) 1993-07-01
WO1991007986A1 (en) 1991-06-13
FI922551A0 (fi) 1992-06-03
FI922551L (fi) 1992-06-03
EP0504307B1 (de) 1994-01-19
AU7179491A (en) 1991-06-26
DK0504307T3 (da) 1994-03-21
EP0504307A1 (de) 1992-09-23
DE69006221T2 (de) 1994-05-05
JPH0747547B2 (ja) 1995-05-24
ES2062762T3 (es) 1994-12-16
FI922551A7 (fi) 1992-06-03

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Legal Events

Date Code Title Description
UEP Publication of translation of european patent specification
REN Ceased due to non-payment of the annual fee