ES2062762T3 - Metodo para tratar el choque septico. - Google Patents
Metodo para tratar el choque septico.Info
- Publication number
- ES2062762T3 ES2062762T3 ES91902317T ES91902317T ES2062762T3 ES 2062762 T3 ES2062762 T3 ES 2062762T3 ES 91902317 T ES91902317 T ES 91902317T ES 91902317 T ES91902317 T ES 91902317T ES 2062762 T3 ES2062762 T3 ES 2062762T3
- Authority
- ES
- Spain
- Prior art keywords
- septic shock
- treating septic
- antagonist
- human
- treating
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
- C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
- C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
- C07K16/244—Interleukins [IL]
- C07K16/248—IL-6
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Medicinal Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Cardiology (AREA)
- Oncology (AREA)
- Heart & Thoracic Surgery (AREA)
- Immunology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Biochemistry (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Molecular Biology (AREA)
- Biophysics (AREA)
- Communicable Diseases (AREA)
- Genetics & Genomics (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Peptides Or Proteins (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Compression-Type Refrigeration Machines With Reversible Cycles (AREA)
- Spinning Or Twisting Of Yarns (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
- Treatment Of Sludge (AREA)
- Fertilizers (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Abstract
SE FACILITA UN METODO DE TRATAMIENTO DEL SHOCK SEPTICO. EL METODO COMPRENDE LA ADMINISTRACION DE UNA CANTIDAD EFICAZ DE UN ANTAGONISTA AL IL-6 HUMANO. PREFERIBLEMENTE, EL ANTAGONISTA ES UN ANTICUERPO MONOCLONAL DE BLOQUEO ESPECIFICO PARA EL IL-6 HUMANO O UNA COMPOSICION DE UN FRAGMENTO O DE UN LIGANTE DERIVADA DEL MISMO.
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US44519289A | 1989-12-04 | 1989-12-04 |
Publications (1)
Publication Number | Publication Date |
---|---|
ES2062762T3 true ES2062762T3 (es) | 1994-12-16 |
Family
ID=23767939
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
ES91902317T Expired - Lifetime ES2062762T3 (es) | 1989-12-04 | 1990-11-30 | Metodo para tratar el choque septico. |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0504307B1 (es) |
JP (1) | JPH0747547B2 (es) |
AT (1) | ATE100331T1 (es) |
AU (1) | AU648777B2 (es) |
CA (1) | CA2070424A1 (es) |
DE (1) | DE69006221T2 (es) |
DK (1) | DK0504307T3 (es) |
ES (1) | ES2062762T3 (es) |
FI (1) | FI922551A (es) |
HU (1) | HUT64481A (es) |
WO (1) | WO1991007986A1 (es) |
Families Citing this family (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
WO1994009138A1 (en) * | 1992-10-20 | 1994-04-28 | Cetus Oncology Corporation | Interleukin-6 receptor antagonists |
JP3525221B2 (ja) * | 1993-02-17 | 2004-05-10 | 味の素株式会社 | 免疫抑制剤 |
RU2139092C1 (ru) * | 1993-06-03 | 1999-10-10 | Терапьютик Антибодиз Инк. | Фрагменты антител в терапии |
DE4409513C1 (de) * | 1994-02-07 | 1995-10-19 | Knoll Ag | Verwendung von anti-TNF-Antikörpern als Arzneimittel zur Behandlung von Erkrankungen mit einem erhöhten Interleukin-6 Serumspiegel |
US8017121B2 (en) | 1994-06-30 | 2011-09-13 | Chugai Seiyaku Kabushika Kaisha | Chronic rheumatoid arthritis therapy containing IL-6 antagonist as effective component |
CN101361972B (zh) * | 1994-10-07 | 2011-05-25 | 中外制药株式会社 | 以il-6拮抗剂作为有效成分治疗慢性类风湿性关节炎 |
EP1001805A1 (en) * | 1997-06-18 | 2000-05-24 | The Rockefeller University | Methods for identifying antibodies and peptides useful in the treatment of septic shock and experimental arthritis and uses thereof |
CN102089326B (zh) | 2008-05-13 | 2014-12-31 | 诺维莫尼公司 | 抗白细胞介素-6/白细胞介素-6受体的抗体及其使用方法 |
US8188235B2 (en) | 2008-06-18 | 2012-05-29 | Pfizer Inc. | Antibodies to IL-6 and their uses |
Family Cites Families (4)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2598666B2 (ja) * | 1987-10-19 | 1997-04-09 | 忠三 岸本 | 抗ヒトbcdfモノクローナル抗体 |
CA1341588C (en) * | 1988-01-26 | 2009-01-06 | Michel Revel | Human ifn-beta2/i1-6, its purification and use |
JPH03500050A (ja) * | 1988-02-02 | 1991-01-10 | シェリング・バイオテック・コーポレーション | 免疫グロブリンeの応答を減少させる方法 |
EP0399429A1 (en) * | 1989-05-22 | 1990-11-28 | Toray Industries, Inc. | Anti-human interleukin-6 monoclonal antibody |
-
1990
- 1990-11-30 DE DE91902317T patent/DE69006221T2/de not_active Expired - Fee Related
- 1990-11-30 HU HU9201859A patent/HUT64481A/hu unknown
- 1990-11-30 ES ES91902317T patent/ES2062762T3/es not_active Expired - Lifetime
- 1990-11-30 WO PCT/US1990/006872 patent/WO1991007986A1/en active IP Right Grant
- 1990-11-30 CA CA002070424A patent/CA2070424A1/en not_active Abandoned
- 1990-11-30 JP JP3502346A patent/JPH0747547B2/ja not_active Expired - Lifetime
- 1990-11-30 DK DK91902317.6T patent/DK0504307T3/da active
- 1990-11-30 AU AU71794/91A patent/AU648777B2/en not_active Ceased
-
1991
- 1991-06-28 AT AT91902317T patent/ATE100331T1/de not_active IP Right Cessation
- 1991-06-28 EP EP91902317A patent/EP0504307B1/en not_active Expired - Lifetime
-
1992
- 1992-06-03 FI FI922551A patent/FI922551A/fi not_active Application Discontinuation
Also Published As
Publication number | Publication date |
---|---|
EP0504307A1 (en) | 1992-09-23 |
HU9201859D0 (en) | 1992-09-28 |
FI922551A0 (fi) | 1992-06-03 |
WO1991007986A1 (en) | 1991-06-13 |
AU7179491A (en) | 1991-06-26 |
JPH0747547B2 (ja) | 1995-05-24 |
FI922551A (fi) | 1992-06-03 |
EP0504307B1 (en) | 1994-01-19 |
JPH05504058A (ja) | 1993-07-01 |
DK0504307T3 (da) | 1994-03-21 |
WO1991007986A8 (en) | 2004-04-22 |
CA2070424A1 (en) | 1991-06-05 |
DE69006221T2 (de) | 1994-05-05 |
HUT64481A (en) | 1994-01-28 |
DE69006221D1 (de) | 1994-03-03 |
ATE100331T1 (de) | 1994-02-15 |
AU648777B2 (en) | 1994-05-05 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
FG2A | Definitive protection |
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