DK0494268T3 - Fremgangsmåde til inhibering af stamcellers vækst - Google Patents

Fremgangsmåde til inhibering af stamcellers vækst

Info

Publication number
DK0494268T3
DK0494268T3 DK90916178.8T DK90916178T DK0494268T3 DK 0494268 T3 DK0494268 T3 DK 0494268T3 DK 90916178 T DK90916178 T DK 90916178T DK 0494268 T3 DK0494268 T3 DK 0494268T3
Authority
DK
Denmark
Prior art keywords
stem cell
cell growth
inhibiting stem
agents
inhibiting
Prior art date
Application number
DK90916178.8T
Other languages
English (en)
Other versions
DK0494268T4 (da
Inventor
Ian B Pragnell
Debra D Donaldson
Gerald J Graham
Gordon G Wong
Original Assignee
Genetics Inst
Crc Technology Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Family has litigation
First worldwide family litigation filed litigation Critical https://patents.darts-ip.com/?family=27021719&utm_source=google_patent&utm_medium=platform_link&utm_campaign=public_patent_search&patent=DK0494268(T3) "Global patent litigation dataset” by Darts-ip is licensed under a Creative Commons Attribution 4.0 International License.
Application filed by Genetics Inst, Crc Technology Ltd filed Critical Genetics Inst
Publication of DK0494268T3 publication Critical patent/DK0494268T3/da
Application granted granted Critical
Publication of DK0494268T4 publication Critical patent/DK0494268T4/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52—Cytokines; Lymphokines; Interferons
    • C07K14/521—Chemokines
    • C07K14/523—Beta-chemokines, e.g. RANTES, I-309/TCA-3, MIP-1alpha, MIP-1beta/ACT-2/LD78/SCIF, MCP-1/MCAF, MCP-2, MCP-3, LDCF-1, LDCF-2
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Immunology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Zoology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Plant Substances (AREA)
DK90916178T 1989-09-25 1990-09-25 Fremgangsmåde til inhibering af stamcellers vækst DK0494268T4 (da)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US41230389A 1989-09-25 1989-09-25
US58171390A 1990-09-13 1990-09-13
PCT/US1990/005451 WO1991004274A1 (en) 1989-09-25 1990-09-25 Method for inhibiting growth of stem cells

Publications (2)

Publication Number Publication Date
DK0494268T3 true DK0494268T3 (da) 1995-08-28
DK0494268T4 DK0494268T4 (da) 1999-11-08

Family

ID=27021719

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90916178T DK0494268T4 (da) 1989-09-25 1990-09-25 Fremgangsmåde til inhibering af stamcellers vækst

Country Status (10)

Country Link
US (1) US5674841A (da)
EP (1) EP0494268B2 (da)
JP (1) JPH05502443A (da)
AT (1) ATE124421T1 (da)
CA (1) CA2064558C (da)
DE (1) DE69020573T3 (da)
DK (1) DK0494268T4 (da)
ES (1) ES2076378T5 (da)
MX (1) MX9203438A (da)
WO (1) WO1991004274A1 (da)

Families Citing this family (39)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPH06503710A (ja) * 1990-09-14 1994-04-28 カイロン　コーポレイション 酵母細胞におけるマクロファージ誘導タンパク質（ｍｉｐ）の発現
US6057123A (en) * 1991-12-23 2000-05-02 British Biotech Pharmaceuticals Limited Stem cell inhibiting proteins
FR2691153B1 (fr) * 1992-05-18 1995-06-30 Serbio Dodecapeptides monomere et dimere, utilisation en tant qu'agents anti-megacaryocytaires.
US6610654B2 (en) 1993-03-31 2003-08-26 Wellstat Therapeutics Corporation Inhibitor of stem cell proliferation and uses thereof
CN1089344C (zh) * 1993-03-31 2002-08-21 普罗神经细胞有限公司 干细胞增生的抑制剂及其应用
US5939391A (en) * 1993-03-31 1999-08-17 Pro-Neuron, Inc. Hemoglobin alpha chain peptide fragments useful for inhibiting stem cell proliferation
GB9308060D0 (en) * 1993-04-19 1993-06-02 Cancer Res Campaign Tech Stem cell inhibitor
EP0703784B1 (en) * 1993-06-15 2002-03-06 British Biotech Pharmaceuticals Limited Release and mobilisation of haematopoietic cells
US6488925B2 (en) 1993-12-22 2002-12-03 Human Genome Sciences, Inc. Macrophage inflammatory protein-4 (MIP-4) polypeptides
US6001606A (en) * 1994-03-08 1999-12-14 Human Genome Sciences, Inc. Polynucleotides encoding myeloid progenitor inhibitory factor-1 (MPIF-1) and polypeptides encoded thereby
US6811773B1 (en) 1993-12-22 2004-11-02 Human Genome Sciences, Inc. Human monocyte colony inhibitory factor (M-CIF) polypeptides
US6623942B2 (en) 1994-03-08 2003-09-23 Human Genome Sciences, Inc. Macrophage inflammatory protein-4 (MIP-4) polynucleotides
US6495129B1 (en) 1994-03-08 2002-12-17 Human Genome Sciences, Inc. Methods of inhibiting hematopoietic stem cells using human myeloid progenitor inhibitory factor-1 (MPIF-1) (Ckbeta-8/MIP-3)
ATE216425T1 (de) * 1994-08-13 2002-05-15 Roche Diagnostics Gmbh Verwendung von interferon-gamma zur vermeidung der proliferation und differenzierung der primitiven hämapoietischen vorläuferzellen
EP0696639B1 (en) * 1994-08-13 2002-04-17 Boehringer Mannheim Gmbh Use of interferon gamma for the inhibition of proliferation and differentiation of primitive hematopoietic progenitor cells
US6391589B1 (en) 1994-08-23 2002-05-21 Human Genome Sciences, Inc. Human chemokine beta-10 mutant polypeptides
US6174995B1 (en) 1994-08-23 2001-01-16 Haodong Li Human chemokines, CKβ4 and CKβ10/MCP-4
US5981230A (en) * 1994-08-23 1999-11-09 Human Genome Sciences, Inc. Polynucleotide encoding chemokine β-4
US6458349B1 (en) 1995-06-02 2002-10-01 Human Genome Sciences, Inc. Chemokine β-4 polypeptides
US6139832A (en) * 1995-02-08 2000-10-31 Human Genome Sciences, Inc. Leukocyte adhesion inhibitor-1 (LAI-1) Polypeptides
US6040431A (en) * 1995-06-07 2000-03-21 Stryker Corporation Single chain analogs of the TGF-β superfamily (morphons)
AU1840897A (en) * 1996-02-09 1997-08-28 Katholieke Universiteit Nijmegen Mammalian dendritic cell chemokine reagents
US6410268B1 (en) 1996-03-18 2002-06-25 Human Genome Sciences, Inc. Polynucleotides encoding chemokine alpha-3
US5910431A (en) * 1996-03-19 1999-06-08 Human Genome Sciences, Inc. Polynucleotides encoding chemokine α-2
US5861483A (en) 1996-04-03 1999-01-19 Pro-Neuron, Inc. Inhibitor of stem cell proliferation and uses thereof
US6290948B1 (en) * 1996-05-14 2001-09-18 Smithkline Beecham Corporation Method of treating sepsis and ARDS using chamohine beta-10
AU762472B2 (en) 1998-03-13 2003-06-26 University Of British Columbia, The Therapeutic chemokine receptor antagonists
CA2305787A1 (en) 2000-05-09 2001-11-09 The University Of British Columbia Cxcr4 antagonist treatment of hematopoietic cells
CA2245224A1 (en) 1998-08-14 2000-02-14 Jiang-Hong Giong Chemokine receptor antagonists and chemotherapeutics
US7097832B1 (en) 1999-03-30 2006-08-29 Myocardial Therapeutics, Inc. Intramyocardial injection of autologous bone marrow
DK1171165T3 (da) * 1999-03-30 2007-09-03 Ran Kornowski Injektion af autolog knoglemarv i myokardiet
US7368425B2 (en) 2006-03-24 2008-05-06 Chemokine Therapeutics Corp. Cyclic peptides for modulating growth of neo-vessels and their use in therapeutic angiogenesis
CA2335109A1 (en) * 2000-04-12 2001-10-12 Chemokine Therapeutics Corporation Cxcr4 agonist treatment of hematopoietic cells
US20050059584A1 (en) 2002-08-16 2005-03-17 Ahmed Merzouk Novel chemokine mimetics synthesis and their use
US7378098B2 (en) 2000-04-12 2008-05-27 The University Of British Columbia CXC chemokine receptor 4 agonist peptides
JP2004504834A (ja) 2000-08-01 2004-02-19 イスム　リサーチ　ディベロップメント　カンパニー 胚性細胞の定方向分化
AU2003225237A1 (en) 2002-05-01 2003-11-17 Human Genome Sciences, Inc. Antibodies that specifically bind to chemokine beta-4
US8921315B1 (en) * 2008-04-24 2014-12-30 Neumedicines, Inc. Method of increasing survival of a human subject having exposure to an acute exposure to non-therapeutic whole body ionization by administering a therapeutically effective dose of IL-12
KR101919170B1 (ko) 2010-11-19 2018-11-15 에자이 알앤드디 매니지먼트 가부시키가이샤 중화 항-ccl20 항체

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4822776A (en) * 1981-09-08 1989-04-18 The Rockefeller University Lipoprotein lipase suppression by endotoxin-induced mediator (shock assay)
DK175308B1 (da) * 1987-09-28 2004-08-16 Pfizer En vaccinekomposition omfattende et inaktiveret virus eller bakterium, fremgangsmåde til fremstilling deraf samt anvendelsen af en substans eller en komposition i fremstillingen deraf
US5041289A (en) * 1987-11-13 1991-08-20 Becton Dickinson And Company Method of purging residual tumor cells in vitro with lymphokine activated cytotoxic cells
JPH04500970A (ja) * 1988-09-02 1992-02-20 ザ ロックフェラー ユニヴァーシティ マクロファージ由来炎症メディエーター　（ｍｉｐ―２）
WO1991000103A1 (en) * 1989-06-29 1991-01-10 The United States Of America, Represented By The Secretary, United States Department Of Commerce Method for protecting bone marrow against chemotherapeutic drugs and radiation therapy using transforming growth factor beta 1

Also Published As

Publication number Publication date
EP0494268B2 (en) 1999-04-28
CA2064558C (en) 2001-01-30
US5674841A (en) 1997-10-07
DE69020573D1 (de) 1995-08-03
DE69020573T3 (de) 1999-12-16
DE69020573T2 (de) 1995-11-30
ES2076378T5 (es) 1999-10-16
MX9203438A (es) 1992-07-01
WO1991004274A1 (en) 1991-04-04
DK0494268T4 (da) 1999-11-08
ATE124421T1 (de) 1995-07-15
CA2064558A1 (en) 1991-03-26
JPH05502443A (ja) 1993-04-28
EP0494268B1 (en) 1995-06-28
EP0494268A1 (en) 1992-07-15
ES2076378T3 (es) 1995-11-01

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