DK0489877T3 - Antiatherosklerotiske og antithrombotiske 2-amino-6-phenyl-4H-pyran-4-oner - Google Patents
Antiatherosklerotiske og antithrombotiske 2-amino-6-phenyl-4H-pyran-4-onerInfo
- Publication number
- DK0489877T3 DK0489877T3 DK91910593.2T DK91910593T DK0489877T3 DK 0489877 T3 DK0489877 T3 DK 0489877T3 DK 91910593 T DK91910593 T DK 91910593T DK 0489877 T3 DK0489877 T3 DK 0489877T3
- Authority
- DK
- Denmark
- Prior art keywords
- antiatherosclerotic
- antithrombotic
- pyran
- ones
- phenyl
- Prior art date
Links
- 230000000879 anti-atherosclerotic effect Effects 0.000 title abstract 2
- BQFSUTKRBKUWTL-UHFFFAOYSA-N 2-amino-6-phenylpyran-4-one Chemical class O1C(N)=CC(=O)C=C1C1=CC=CC=C1 BQFSUTKRBKUWTL-UHFFFAOYSA-N 0.000 title 1
- 230000002785 anti-thrombosis Effects 0.000 title 1
- 239000003146 anticoagulant agent Substances 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 2
- 239000003112 inhibitor Substances 0.000 abstract 2
- 230000004663 cell proliferation Effects 0.000 abstract 1
- 239000003795 chemical substances by application Substances 0.000 abstract 1
- 201000010099 disease Diseases 0.000 abstract 1
- 208000037265 diseases, disorders, signs and symptoms Diseases 0.000 abstract 1
- 230000002062 proliferating effect Effects 0.000 abstract 1
- 208000010110 spontaneous platelet aggregation Diseases 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
- C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
- C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P7/00—Drugs for disorders of the blood or the extracellular fluid
- A61P7/02—Antithrombotic agents; Anticoagulants; Platelet aggregation inhibitors
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D309/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings
- C07D309/34—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D309/36—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms
- C07D309/38—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only ring hetero atom, not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with oxygen atoms directly attached to ring carbon atoms one oxygen atom in position 2 or 4, e.g. pyrones
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Hematology (AREA)
- Diabetes (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Pyrane Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US54593590A | 1990-06-29 | 1990-06-29 |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0489877T3 true DK0489877T3 (da) | 1996-02-05 |
Family
ID=24178137
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK91910593.2T DK0489877T3 (da) | 1990-06-29 | 1991-06-03 | Antiatherosklerotiske og antithrombotiske 2-amino-6-phenyl-4H-pyran-4-oner |
Country Status (11)
| Country | Link |
|---|---|
| EP (1) | EP0489877B1 (de) |
| JP (1) | JPH05501886A (de) |
| KR (1) | KR920702353A (de) |
| AT (1) | ATE128128T1 (de) |
| AU (1) | AU630822B2 (de) |
| CA (1) | CA2064796A1 (de) |
| DE (1) | DE69113221T2 (de) |
| DK (1) | DK0489877T3 (de) |
| ES (1) | ES2079068T3 (de) |
| GR (1) | GR3018304T3 (de) |
| WO (1) | WO1992000290A1 (de) |
Families Citing this family (17)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2687674B1 (fr) * | 1992-02-07 | 1995-05-19 | Roussel Uclaf | Nouveaux derives de la pyridone, leur procede de preparation, les nouveaux intermediaires obtenus, leur application a titre de medicaments et les compositions pharmaceutiques les renfermant. |
| US5834024A (en) * | 1995-01-05 | 1998-11-10 | Fh Faulding & Co. Limited | Controlled absorption diltiazem pharmaceutical formulation |
| TW587079B (en) * | 1998-09-25 | 2004-05-11 | Almirall Prodesfarma Ag | 2-phenylpyran-4-one derivatives |
| JP2004505014A (ja) * | 2000-04-05 | 2004-02-19 | ファルマシア・コーポレーション | 凝血カスケードの選択的阻害に有用な多環式アリールおよびヘテロアリール置換された４−ピロン類 |
| GB2405093B (en) * | 2001-08-14 | 2005-07-06 | Cancer Rec Tech Ltd | DNA-PK inhibitors |
| GB0119863D0 (en) | 2001-08-14 | 2001-10-10 | Cancer Res Campaign Tech | DNA-PK inhibitors |
| GB0119865D0 (en) * | 2001-08-14 | 2001-10-10 | Cancer Res Campaign Tech | DNA-PK inhibitors |
| PL370074A1 (en) * | 2002-02-25 | 2005-05-16 | Kudos Pharmaceuticals Ltd | Pyranones useful as atm inhibitors |
| GB0204350D0 (en) * | 2002-02-25 | 2002-04-10 | Kudos Pharm Ltd | ATM inhibitors |
| US7049313B2 (en) | 2002-02-25 | 2006-05-23 | Kudos Pharmaceuticals Ltd. | ATM inhibitors |
| MXPA06001599A (es) | 2003-08-13 | 2006-05-19 | Kudos Pharm Ltd | Aminopironas y su uso como inhibidores de atm. |
| RU2408596C2 (ru) | 2004-09-20 | 2011-01-10 | Кудос Фармасьютикалс Лимитед | Ингибиторы днк-пк |
| JP2008529995A (ja) | 2005-02-09 | 2008-08-07 | クドス ファーマシューティカルズ リミテッド | Ａｔｍ阻害剤 |
| AR054438A1 (es) | 2005-04-15 | 2007-06-27 | Kudos Pharm Ltd | Inhibidores de adn -pk |
| ES2534573T3 (es) | 2007-04-06 | 2015-04-24 | Neurocrine Biosciences, Inc. | Antagonistas del receptor de la hormona liberadora de gonadotropina y métodos relacionados con los mismos |
| WO2008124614A1 (en) | 2007-04-06 | 2008-10-16 | Neurocrine Biosciences, Inc. | Gonadotropin-releasing hormone receptor antagonists and methods relating thereto |
| CN102731456B (zh) * | 2011-04-01 | 2014-07-09 | 华中科技大学 | 一种抗肿瘤化合物及其制备方法和应用 |
Family Cites Families (2)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| FR2452487A1 (fr) * | 1979-03-28 | 1980-10-24 | Rhone Poulenc Agrochimie | Nouveaux derives de la phenyl-2-pyrone-4 et leur utilisation comme fongicides |
| RU2118321C1 (ru) * | 1988-12-21 | 1998-08-27 | Дзе Апджон Компани | Замещенные бензопираноны и их фармацевтически приемлемые соли и гидраты |
-
1991
- 1991-06-03 CA CA002064796A patent/CA2064796A1/en not_active Abandoned
- 1991-06-03 KR KR1019920700451A patent/KR920702353A/ko not_active Ceased
- 1991-06-03 AT AT91910593T patent/ATE128128T1/de not_active IP Right Cessation
- 1991-06-03 AU AU79554/91A patent/AU630822B2/en not_active Ceased
- 1991-06-03 ES ES91910593T patent/ES2079068T3/es not_active Expired - Lifetime
- 1991-06-03 DK DK91910593.2T patent/DK0489877T3/da active
- 1991-06-03 JP JP3510284A patent/JPH05501886A/ja active Pending
- 1991-06-03 EP EP91910593A patent/EP0489877B1/de not_active Expired - Lifetime
- 1991-06-03 DE DE69113221T patent/DE69113221T2/de not_active Expired - Fee Related
- 1991-06-03 WO PCT/US1991/003659 patent/WO1992000290A1/en not_active Ceased
-
1995
- 1995-12-05 GR GR950403423T patent/GR3018304T3/el unknown
Also Published As
| Publication number | Publication date |
|---|---|
| CA2064796A1 (en) | 1991-12-30 |
| AU7955491A (en) | 1992-01-23 |
| GR3018304T3 (en) | 1996-03-31 |
| WO1992000290A1 (en) | 1992-01-09 |
| EP0489877B1 (de) | 1995-09-20 |
| KR920702353A (ko) | 1992-09-03 |
| ATE128128T1 (de) | 1995-10-15 |
| JPH05501886A (ja) | 1993-04-08 |
| AU630822B2 (en) | 1992-11-05 |
| ES2079068T3 (es) | 1996-01-01 |
| DE69113221T2 (de) | 1996-03-28 |
| EP0489877A1 (de) | 1992-06-17 |
| DE69113221D1 (en) | 1995-10-26 |
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