DK0489767T3 - CCK-antagonister - Google Patents
CCK-antagonisterInfo
- Publication number
- DK0489767T3 DK0489767T3 DK90912437.2T DK90912437T DK0489767T3 DK 0489767 T3 DK0489767 T3 DK 0489767T3 DK 90912437 T DK90912437 T DK 90912437T DK 0489767 T3 DK0489767 T3 DK 0489767T3
- Authority
- DK
- Denmark
- Prior art keywords
- inclusive
- carbon atoms
- group
- alkyl group
- hydroxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/10—Indoles; Hydrogenated indoles with substituted hydrocarbon radicals attached to carbon atoms of the hetero ring
- C07D209/14—Radicals substituted by nitrogen atoms, not forming part of a nitro radical
- C07D209/16—Tryptamines
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
- C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
- C07D209/04—Indoles; Hydrogenated indoles
- C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
- C07D209/42—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/06—Dipeptides
- C07K5/06139—Dipeptides with the first amino acid being heterocyclic
- C07K5/06156—Dipeptides with the first amino acid being heterocyclic and Trp-amino acid; Derivatives thereof
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
- C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
- C07K5/08—Tripeptides
- C07K5/0821—Tripeptides with the first amino acid being heterocyclic, e.g. His, Pro, Trp
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Biophysics (AREA)
- General Health & Medical Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Indole Compounds (AREA)
- Saccharide Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/396,567 US5010089A (en) | 1988-08-12 | 1989-08-21 | CCK antagonists and their use in treating gastrointestinal disorders |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0489767T3 true DK0489767T3 (da) | 1996-12-09 |
Family
ID=23567756
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90912437.2T DK0489767T3 (da) | 1989-08-21 | 1990-08-20 | CCK-antagonister |
Country Status (13)
| Country | Link |
|---|---|
| US (1) | US5010089A (es) |
| EP (1) | EP0489767B1 (es) |
| JP (1) | JPH05500049A (es) |
| AT (1) | ATE145405T1 (es) |
| CA (1) | CA2064897A1 (es) |
| DE (1) | DE69029198T2 (es) |
| DK (1) | DK0489767T3 (es) |
| ES (1) | ES2095878T3 (es) |
| GR (1) | GR1001001B (es) |
| IE (1) | IE903009A1 (es) |
| NO (1) | NO920677L (es) |
| PT (1) | PT95059B (es) |
| WO (1) | WO1991002719A2 (es) |
Families Citing this family (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5593967A (en) * | 1990-08-31 | 1997-01-14 | Warner-Lambert Company | Cholecystokinin antagonists, their preparation and therapeutic use |
| JP3361100B2 (ja) * | 1994-03-10 | 2003-01-07 | ワーナー−ランバート・コンパニー | Ｃｃｋ受容体アンタゴニストとしてのインドール誘導体 |
| JP3314938B2 (ja) * | 1995-06-06 | 2002-08-19 | ファイザー・インコーポレーテッド | グリコーゲンホスホリラーゼ抑制剤としての置換されたｎ−（インドール−２−カルボニル）−グリシンアミド類および誘導体 |
| MY114711A (en) | 1995-06-06 | 2002-12-31 | Pfizer | Substituted n-(indole-2-carbonyl)-b-alanmamides and derivatives as antidiabetic agents |
| AP9600817A0 (en) | 1995-06-06 | 1996-07-31 | Pfizer | Novel cryatal form of anhydrous 7-( [1A,5A,6A]-6-amino3-3-azabicyclo [3.1.0.] hex-3-yl) -6-fluro-1-(2,4-difluorophenyl)-1,4-dihydro-4-oxo-1, 8-naphthyridine-3-carboxylic acid, methanesulfonic acid salt. |
| US6277877B1 (en) | 2000-08-15 | 2001-08-21 | Pfizer, Inc. | Substituted n-(indole-2-carbonyl)glycinamides and derivates as glycogen phosphorylase inhibitors |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US4482567A (en) * | 1982-10-07 | 1984-11-13 | Research Foundation For Mental Hygiene, Inc. | N-hexanoyl to n-heptadecanoyl 5-hydroxy tryptophan-5-hydroxytryptophanamides and use as analgesics |
| US4757151A (en) * | 1985-11-14 | 1988-07-12 | Warner-Lambert Company | 2-substituted-[2-substituted-amino]-N-arylalkyl-3-[indol-3-yl] |
| US4814463A (en) * | 1985-12-31 | 1989-03-21 | Biomeasure, Inc. | CCK antagonists |
| US4803284A (en) * | 1987-08-19 | 1989-02-07 | Centro De Investigacion Y De Estudios Avanzados Del Instituto Politecnico Nacional | Processes for the preparation of 3-amino-2-(5-methoxy-1H-indol-3-yl) propionic acid monohydrate |
-
1989
- 1989-08-21 US US07/396,567 patent/US5010089A/en not_active Expired - Fee Related
-
1990
- 1990-08-20 DE DE69029198T patent/DE69029198T2/de not_active Expired - Fee Related
- 1990-08-20 WO PCT/US1990/004703 patent/WO1991002719A2/en active IP Right Grant
- 1990-08-20 CA CA002064897A patent/CA2064897A1/en not_active Abandoned
- 1990-08-20 ES ES90912437T patent/ES2095878T3/es not_active Expired - Lifetime
- 1990-08-20 DK DK90912437.2T patent/DK0489767T3/da active
- 1990-08-20 AT AT90912437T patent/ATE145405T1/de not_active IP Right Cessation
- 1990-08-20 JP JP2511922A patent/JPH05500049A/ja active Pending
- 1990-08-20 IE IE300990A patent/IE903009A1/en unknown
- 1990-08-20 EP EP90912437A patent/EP0489767B1/en not_active Expired - Lifetime
- 1990-08-21 PT PT95059A patent/PT95059B/pt not_active IP Right Cessation
- 1990-08-21 GR GR900100625A patent/GR1001001B/el unknown
-
1992
- 1992-02-20 NO NO92920677A patent/NO920677L/no unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO920677D0 (no) | 1992-02-20 |
| PT95059B (pt) | 1997-12-31 |
| IE903009A1 (en) | 1991-02-27 |
| JPH05500049A (ja) | 1993-01-14 |
| ATE145405T1 (de) | 1996-12-15 |
| GR1001001B (el) | 1993-03-31 |
| WO1991002719A2 (en) | 1991-03-07 |
| EP0489767A1 (en) | 1992-06-17 |
| US5010089A (en) | 1991-04-23 |
| PT95059A (pt) | 1991-05-22 |
| NO920677L (no) | 1992-04-07 |
| GR900100625A (en) | 1991-12-30 |
| ES2095878T3 (es) | 1997-03-01 |
| EP0489767B1 (en) | 1996-11-20 |
| EP0489767A4 (en) | 1992-07-08 |
| WO1991002719A3 (en) | 1991-04-04 |
| DE69029198T2 (de) | 1997-04-24 |
| CA2064897A1 (en) | 1991-02-22 |
| DE69029198D1 (de) | 1997-01-02 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| PT776324E (pt) | Antagonista da endotelina | |
| CO4340622A1 (es) | Nuevos macrociclos bis-indolil maleimida | |
| DK0622361T3 (da) | Heterocykliske forbindelser som bradykininantagonister | |
| NO930817L (no) | Imidazolderivater med bifenylsulfonylurea- eller bifenylsulfonyluretan-sidekjeder, fremgangsmaate for deres fremstilling og deres anvendelse | |
| NO921835D0 (no) | Fremgangsmaate for fremstilling av amidinofenylalaninderivat samt anvendelse derav | |
| ATE154021T1 (de) | N-cyclohexyl benzamide derivate, ihre herstellungen und therapeutischen anwendungen | |
| ATE110365T1 (de) | 2-alkyl-4-arylmethylaminochinoline, ihre verwendung und daraus hergestellte arzneimittel. | |
| DK0489767T3 (da) | CCK-antagonister | |
| NO952743D0 (no) | Ny benzotiadiazinforbindelse, dens fremstilling og farmasöytiske preparater | |
| DK484787A (da) | Bis-dioxopiperazin-derivater | |
| ATE123292T1 (de) | Cck-antagonisten. | |
| ES2039363T3 (es) | Procedimiento para la obtencion de pirrolo (1,2-a)(4,1) benzoxazepinas. | |
| ES2077985T3 (es) | Inhibidores de la acil-coa: colesterol-acil transferasa, a base de 5-bis-aminometilen-1,3-dioxano-4,6-diona n,n',n'-trisubstituida. | |
| ECSP910725A (es) | Procedimiento para preparar nuevos derivados de 4( 1h) quinolona | |
| BG50775A1 (en) | Derivatives of 2, 3- dimethyl- 1- phenyl- 4- (2- phenylmorpholinomethyl)- 5- pyrazolones and method for their preparation |