DK0481058T3 - Humant, lymfatisk væv i en immunokompromitteret vært - Google Patents

Humant, lymfatisk væv i en immunokompromitteret vært

Info

Publication number
DK0481058T3
DK0481058T3 DK91909374.0T DK91909374T DK0481058T3 DK 0481058 T3 DK0481058 T3 DK 0481058T3 DK 91909374 T DK91909374 T DK 91909374T DK 0481058 T3 DK0481058 T3 DK 0481058T3
Authority
DK
Denmark
Prior art keywords
immunocompromised host
human
lymphatic tissue
tissue
human lymphatic
Prior art date
Application number
DK91909374.0T
Other languages
Danish (da)
English (en)
Inventor
Susan Mayo
Reiko Namikawa
Hideto Kaneshima
Joseph M Mccune
Original Assignee
Systemix Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Systemix Inc filed Critical Systemix Inc
Application granted granted Critical
Publication of DK0481058T3 publication Critical patent/DK0481058T3/da

Links

Classifications

    • A—HUMAN NECESSITIES
    • A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
    • A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
    • A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
    • A01K67/027—New or modified breeds of vertebrates
    • A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies

Landscapes

  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Environmental Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Cell Biology (AREA)
  • Biodiversity & Conservation Biology (AREA)
  • Genetics & Genomics (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Animal Behavior & Ethology (AREA)
  • Zoology (AREA)
  • Animal Husbandry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Saccharide Compounds (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Orthopedics, Nursing, And Contraception (AREA)
  • Surgical Instruments (AREA)
DK91909374.0T 1990-05-03 1991-04-29 Humant, lymfatisk væv i en immunokompromitteret vært DK0481058T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US51874890A 1990-05-03 1990-05-03

Publications (1)

Publication Number Publication Date
DK0481058T3 true DK0481058T3 (da) 1996-12-02

Family

ID=24065324

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91909374.0T DK0481058T3 (da) 1990-05-03 1991-04-29 Humant, lymfatisk væv i en immunokompromitteret vært

Country Status (11)

Country Link
US (1) US5411749A (fr)
EP (1) EP0481058B1 (fr)
JP (1) JPH04507109A (fr)
AT (1) ATE140480T1 (fr)
AU (1) AU637914B2 (fr)
CA (1) CA2063408A1 (fr)
DE (1) DE69120890T2 (fr)
DK (1) DK0481058T3 (fr)
ES (1) ES2090332T3 (fr)
GR (1) GR3021382T3 (fr)
WO (1) WO1991016910A1 (fr)

Families Citing this family (43)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5849288A (en) * 1990-01-15 1998-12-15 Yeda Research And Development Co. Ltd. Method for production of monoclonal antibodies in chimeric mice or rats having xenogeneic antibody-producing cells
US5652373A (en) * 1990-01-15 1997-07-29 Yeda Research And Development Co. Ltd. Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems
DK9091D0 (da) * 1991-01-18 1991-01-18 Novo Nordisk As Fremgangsmaade til fremstilling af antistoffer
US5858328A (en) * 1991-06-04 1999-01-12 Yeda Research And Development Co. Ltd. Animal model for hepatitis virus infection
US5804160A (en) * 1991-06-04 1998-09-08 Yeda Research And Development Co. Ltd Animal model for hepatitis virus infection
US5849987A (en) * 1992-06-02 1998-12-15 Yeda Research And Development Co. Ltd. Animal model for hepatitis virus infection
DE69229254T2 (de) * 1991-10-30 1999-09-23 Idemitsu Kosan Co Verfahren zur Herstellung von menschlichen Lymphozyten und menschlichen Antikörpern; und so hergestellte Antikörper
US5866757A (en) * 1992-06-02 1999-02-02 Yeda Research And Development Co. Ltd. Engraftment and development of xenogeneic cells in normal mammals having reconstituted hematopoetic deficient immune systems
JP2801085B2 (ja) * 1992-09-11 1998-09-21 ザ リージェンツ オブ ザ ユニバーシティ オブ ミシガン ヒト細胞を植えた気道上の異種移植片を有する非ヒト動物
CA2103693A1 (fr) * 1993-08-06 1995-02-07 Steven Gallinger Modele animal du systeme immunitaire humain
US5645982A (en) * 1993-08-19 1997-07-08 Systemix, Inc. Method for screening potential therapeutically effective antiviral agents
US5516977A (en) * 1993-12-17 1996-05-14 Systemix, Inc. Xenogeneic tissue implant in ear pinna
US6455756B1 (en) * 1994-08-12 2002-09-24 Novartis Ag Long term xenogeneic myeloid and lymphoid cell production in chimeric immunocompromised mice
EP0792294A1 (fr) * 1994-11-16 1997-09-03 Baxter International Inc. Anticorps humains pour les peptides recepteurs de lymphocytes t et leur methode de preparation
US5811524A (en) 1995-06-07 1998-09-22 Idec Pharmaceuticals Corporation Neutralizing high affinity human monoclonal antibodies specific to RSV F-protein and methods for their manufacture and therapeutic use thereof
US20020182730A1 (en) * 1995-07-26 2002-12-05 Micheal L. Gruenberg Autologous immune cell therapy: cell compositions, methods and applications to treatment of human disease
US5986170A (en) * 1995-11-13 1999-11-16 Corixa Corporation Murine model for human carcinoma
JP4312265B2 (ja) * 1997-04-09 2009-08-12 ラング−ジ チャン ワクチン評価のための動物モデル
DE60142614D1 (de) * 2000-01-27 2010-09-02 Medimmune Inc Inität
JP2003525061A (ja) 2000-03-01 2003-08-26 メディミューン，インコーポレイテッド 高効力組換え抗体およびその産生法
US6855493B2 (en) 2000-11-28 2005-02-15 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
US7179900B2 (en) * 2000-11-28 2007-02-20 Medimmune, Inc. Methods of administering/dosing anti-RSV antibodies for prophylaxis and treatment
FR2821947B1 (fr) * 2001-03-12 2003-05-16 Canon Kk Procede et dispositif de validation de parametres definissant une image
US20030134341A1 (en) * 2001-09-19 2003-07-17 Medcell Biologics, Llc. Th1 cell adoptive immunotherapy
US20030134415A1 (en) * 2001-09-19 2003-07-17 Gruenberg Micheal L. Th1 cell adoptive immunotherapy
US20030175272A1 (en) * 2002-03-07 2003-09-18 Medcell Biologics, Inc. Re-activated T-cells for adoptive immunotherapy
US7132100B2 (en) 2002-06-14 2006-11-07 Medimmune, Inc. Stabilized liquid anti-RSV antibody formulations
EP1635763B1 (fr) 2003-06-09 2012-08-08 Alnylam Pharmaceuticals Inc. Procede de traitement de maladie neurodegenerative
CA2585891A1 (fr) * 2004-10-29 2006-05-11 Medimmune, Inc. Methodes de prevention et de traitement des infections a rsv et des etats pathologiques associes
EP1997830A1 (fr) * 2007-06-01 2008-12-03 AIMM Therapeutics B.V. Molécules à liaison spécifiques RSV et leur moyen de fabrication
US20090291073A1 (en) * 2008-05-20 2009-11-26 Ward Keith W Compositions Comprising PKC-theta and Methods for Treating or Controlling Ophthalmic Disorders Using Same
US8349325B2 (en) 2008-12-23 2013-01-08 Abbott Laboratories Soluble FMS-like tyrosine kinase-1 (sFLT-1) antibody and related composition, kit, methods of using, and materials and method for making
US8568726B2 (en) 2009-10-06 2013-10-29 Medimmune Limited RSV specific binding molecule
EP3056082B1 (fr) 2009-10-06 2018-09-05 Regeneron Pharmaceuticals, Inc. Souris génétiquement modifiées et greffe
US20110229921A1 (en) * 2010-03-18 2011-09-22 Abbott Laboratories METHODS OF ASSAYING URINARY NEUTROPHIL GELATINASE-ASSOCIATED LIPOCALIN (uNGAL) IN THE PROGNOSIS OF CADAVERIC KIDNEY TRANSPLANT FUNCTION IN A PATIENT, INCLUDING A PATIENT DIAGNOSED WITH DELAYED GRAFT FUNCTION (DGF), A METHOD OF ASSAYING uNGAL IN THE ASSESSMENT OF RISK OF DGF IN A PATIENT DIAGNOSED WITH EARLY GRAFT FUNCTION (EGF), AND RELATED KITS
WO2011163558A1 (fr) 2010-06-25 2011-12-29 Abbott Laboratories Matériaux et procédés pour le dosage d'anticorps anti-virus de l'hépatite c (hvc)
US20120115244A1 (en) 2010-11-09 2012-05-10 Abbott Laboratories Materials and methods for immunoassay of pterins
MY162984A (en) 2011-02-15 2017-07-31 Regeneron Pharma Humanized m-csf mice
US8993248B2 (en) 2011-12-31 2015-03-31 Abbott Laboratories Truncated human vitamin D binding protein and mutation and fusion thereof and related materials and methods of use
SG10201701759VA (en) 2012-09-07 2017-04-27 Univ Yale Genetically modified non-human animals and methods of use thereof
SG10201707449TA (en) 2012-11-05 2017-10-30 Regeneron Pharma Genetically modified non-human animals and methods of use thereof
EP3482629B1 (fr) 2014-05-19 2020-11-25 Regeneron Pharmaceuticals, Inc. Animaux non humains génétiquement modifiés exprimant l'epo humaine
RU2730599C2 (ru) 2015-04-13 2020-08-24 Ридженерон Фармасьютикалз, Инк. Гуманизированные мыши с нокином sirpa-il15 и способы их использования

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3853201T2 (de) * 1987-12-23 1995-09-14 Univ Leland Stanford Junior Schimäre immunkompromittierende Säugetiere und ihre Verwendung.
JP2981486B2 (ja) * 1988-06-14 1999-11-22 メディカル・バイオロジー・インスティチュート 哺乳動物の免疫系研究方法
DE69131331T2 (de) * 1990-01-15 2000-03-02 Yeda Res & Dev Dauerhafte Verpflanzung und Entwicklung menschlicher hämatopoietischer Zellinien bei normalen Säugetieren
WO1991018615A1 (fr) * 1990-05-25 1991-12-12 Systemix, Inc. Globules de sang peripherique humain chez un hote presentant un deficit immunitaire
JPH04252128A (ja) * 1990-08-03 1992-09-08 Systemix Inc 免疫化された宿主における変性された異種移植器官系

Also Published As

Publication number Publication date
EP0481058A1 (fr) 1992-04-22
DE69120890T2 (de) 1997-02-20
EP0481058A4 (en) 1993-07-14
AU637914B2 (en) 1993-06-10
ATE140480T1 (de) 1996-08-15
ES2090332T3 (es) 1996-10-16
WO1991016910A1 (fr) 1991-11-14
CA2063408A1 (fr) 1991-11-04
JPH04507109A (ja) 1992-12-10
GR3021382T3 (en) 1997-01-31
EP0481058B1 (fr) 1996-07-17
US5411749A (en) 1995-05-02
DE69120890D1 (de) 1996-08-22
AU7858391A (en) 1991-11-27

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