DE69233012T2 - Mit staphylococcus epidermidis assoziierte oberflächenantigene des typs i - Google Patents

Mit staphylococcus epidermidis assoziierte oberflächenantigene des typs i

Info

Publication number
DE69233012T2
DE69233012T2 DE69233012T DE69233012T DE69233012T2 DE 69233012 T2 DE69233012 T2 DE 69233012T2 DE 69233012 T DE69233012 T DE 69233012T DE 69233012 T DE69233012 T DE 69233012T DE 69233012 T2 DE69233012 T2 DE 69233012T2
Authority
DE
Germany
Prior art keywords
type
epidermidis
serotypes
staphylococcus epidermidis
infection
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69233012T
Other languages
English (en)
Other versions
DE69233012D1 (de
Inventor
Ibrahim Fattom
Craig Wright
W Karakawa
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Fattom Ali Ibrahim Rockville Md Us
Wright Dcraig Gaithersburg Md Us
Vaxart Inc
Original Assignee
UNIVAX BIOLOGICS Inc ROCKVILLE
Univax Biologics Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by UNIVAX BIOLOGICS Inc ROCKVILLE, Univax Biologics Inc filed Critical UNIVAX BIOLOGICS Inc ROCKVILLE
Application granted granted Critical
Publication of DE69233012D1 publication Critical patent/DE69233012D1/de
Publication of DE69233012T2 publication Critical patent/DE69233012T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/085—Staphylococcus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/12—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria
    • C07K16/1267—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria
    • C07K16/1271—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from bacteria from Gram-positive bacteria from Micrococcaceae (F), e.g. Staphylococcus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P19/00—Preparation of compounds containing saccharide radicals
    • C12P19/04—Polysaccharides, i.e. compounds containing more than five saccharide radicals attached to each other by glycosidic bonds
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Medicinal Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Wood Science & Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • Microbiology (AREA)
  • Biochemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Zoology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Mycology (AREA)
  • General Engineering & Computer Science (AREA)
  • Epidemiology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
DE69233012T 1991-11-22 1992-11-20 Mit staphylococcus epidermidis assoziierte oberflächenantigene des typs i Expired - Lifetime DE69233012T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US79625291A 1991-11-22 1991-11-22
PCT/US1992/009784 WO1993009811A1 (en) 1991-11-22 1992-11-20 TYPE I AND TYPE II SURFACE ANTIGENS ASSOCIATED WITH $i(STAPHYLOCOCCUS EPIDERMIDIS)

Publications (2)

Publication Number Publication Date
DE69233012D1 DE69233012D1 (de) 2003-05-22
DE69233012T2 true DE69233012T2 (de) 2003-11-06

Family

ID=25167715

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69233012T Expired - Lifetime DE69233012T2 (de) 1991-11-22 1992-11-20 Mit staphylococcus epidermidis assoziierte oberflächenantigene des typs i

Country Status (12)

Country Link
US (2) US5866140A (de)
EP (1) EP0648127B1 (de)
JP (2) JP4087896B2 (de)
AT (1) ATE237351T1 (de)
AU (1) AU681573B2 (de)
CA (1) CA2123811C (de)
DE (1) DE69233012T2 (de)
DK (1) DK0648127T3 (de)
ES (1) ES2198405T3 (de)
FI (1) FI111336B (de)
NO (1) NO319013B1 (de)
WO (1) WO1993009811A1 (de)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5055455A (en) 1988-09-28 1991-10-08 Brigham And Women's Hospital Capsular polysaccharide adhesin antigen, preparation, purification and use
US7279162B1 (en) 1990-10-22 2007-10-09 Henry M. Jackson Foundation For The Advancement Of Military Medicine Isolated broadly reactive opsonic immunoglobulin for treating a pathogenic coagulase-negative staphylococcus infection
US20080139789A1 (en) * 1990-10-22 2008-06-12 Henry M. Jackson Foundation For The Advancement Of Military Medicine Isolated Broadly Reactive Opsonic Immunoglobulin for Treating a Pathogenic Coagulase-Negative Staphylococcus Infection
US5955074A (en) * 1990-10-22 1999-09-21 Henry M. Jackson Foundation For The Advancement Of Military Medicine Directed human immune globulin for the prevention and treatment of staphylococcal infections
ATE209659T1 (de) * 1994-09-21 2001-12-15 Jackson H M Found Military Med Breit-reaktive opsonische antikörper, die mit gemeinsamen staphylococcus-antigenen reagieren
US6610293B1 (en) 1997-06-16 2003-08-26 The Henry M. Jackson Foundation For The Advancement Of Military Medicine Opsonic and protective monoclonal and chimeric antibodies specific for lipoteichoic acid of gram positive bacteria
US7250494B2 (en) 1998-06-15 2007-07-31 Biosynexus Incorporated Opsonic monoclonal and chimeric antibodies specific for lipoteichoic acid of Gram positive bacteria
US7252828B2 (en) 1998-07-15 2007-08-07 The Brigham And Women's Hospital, Inc. Polysaccharide vaccine for staphylococcal infections
US9134303B1 (en) 1998-08-25 2015-09-15 Alere Scarborough, Inc. ICT immunoassay for Legionella pneumophila serogroup 1 antigen employing affinity purified antibodies thereto
US6824997B1 (en) * 1998-09-18 2004-11-30 Binax, Inc. Process and materials for the rapid detection of streptococcus pneumoniae employing purified antigen-specific antibodies
US6692739B1 (en) 1998-08-31 2004-02-17 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
AU762978B2 (en) * 1998-08-31 2003-07-10 Inhibitex, Inc. Staphylococcal immunotherapeutics via donor selection and donor stimulation
US7030101B2 (en) 1998-09-14 2006-04-18 Nabi Biopharmaceuticals Compositions of β-glucans and specific antibodies
WO2000015238A1 (en) * 1998-09-14 2000-03-23 Nabi COMPOSITIONS OF β-GLUCANS AND SPECIFIC IGIV
US6936258B1 (en) * 1999-03-19 2005-08-30 Nabi Biopharmaceuticals Staphylococcus antigen and vaccine
GB9924351D0 (en) 1999-10-14 1999-12-15 Brennan Frank Immunomodulation methods and compositions
WO2001034809A2 (en) * 1999-11-09 2001-05-17 Glaxo Group Limited Staphylococcus epidermidis nucleic acids and proteins
US6703492B1 (en) * 1999-11-09 2004-03-09 Smithkline Beecham Corporation Staphylococcus epidermidis nucleic acids and proteins
US7723087B2 (en) 2002-11-12 2010-05-25 The Brigham And Women's Hospital, Inc. Nucleic acid molecules for enhanced production of a bacterial polysaccharide and methods of use thereof
BRPI0316018B8 (pt) 2002-11-12 2021-05-25 Brigham & Womens Hospital Inc vacina polissacarídica para infecções estafilocócicas
ES2738112T3 (es) 2004-04-21 2020-01-20 Brigham & Womens Hospital Inc Péptidos de fijación a la poli-N-acetil glucosamina (PNAG/dPNAG) y procedimientos para el uso de los mismos
EP1793849A2 (de) * 2004-09-22 2007-06-13 GlaxoSmithKline Biologicals SA Immunogene zusammensetzung zur verwendung bei der impfung gegen staphylokokken
EP2298341A3 (de) 2004-10-21 2011-07-13 Wyeth LLC Immunogene zusammensetzungen von staphylococcus epidermidis polypeptide und polynucleotide antigenen
US20060134141A1 (en) * 2004-12-14 2006-06-22 Nabi Biopharmaceuticals Glycoconjugate vaccines containing peptidoglycan
CA2594533A1 (en) * 2005-01-10 2006-07-20 Nabi Biopharmaceuticals Method of treating staphylococcus aureus infection
US20090074755A1 (en) 2005-06-13 2009-03-19 Nabi Biopharmaceuticals Use of panton-valentine leukocidin for treating and preventing staphylococcus infections
NZ597046A (en) 2006-06-12 2014-01-31 Glaxosmithkline Biolog Sa Use of alpha-toxin for treating and preventing staphylococcus infections
US7754225B2 (en) * 2006-07-20 2010-07-13 Glaxosmithkline Biologicals S.A. Method of protecting against staphylococcal infection
ES2397488T3 (es) * 2007-07-23 2013-03-07 Sanofi Pasteur Limited Polipéptidos inmunógenos y anticuerpos monoclonales
WO2009114520A2 (en) * 2008-03-10 2009-09-17 Pharmain Corporation Compositions for treatment with metallopeptidases, methods of making and using the same
BRPI0916365A2 (pt) 2008-07-21 2018-05-02 Brigham & Womens Hospital Inc métodos e composições relacionados aos oligossacarídeos de glicosina beta-1,6 sintéticos
MX2012000044A (es) 2009-06-22 2012-01-30 Wyeth Llc Composiciones inmunogenicas de antigenos de staphylococcus aureus.
AU2010301043B2 (en) 2009-06-22 2014-01-09 Wyeth Llc Compositions and methods for preparing Staphylococcus aureus serotype 5 and 8 capsular polysaccharide conjugate immunogenic compositions
EP3199177A1 (de) * 2009-10-30 2017-08-02 GlaxoSmithKline Biologicals S.A. Reinigung von kapselförmigen polysacchariden typ 5 und typ 8 aus staphylococcus aureus
BR112013013702A2 (pt) 2010-12-03 2016-09-13 Sanofi Pasteur Ltd composição para imunização contra streptococcus pneumoniae
CN113730648B (zh) * 2021-09-06 2022-11-01 温州瑞司特生物科技有限公司 结合表皮葡萄球菌的水凝胶及其在治疗创面中的应用

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5452794A (en) * 1977-09-30 1979-04-25 Kousaku Yoshida Extracting of polysacchride from capusle containing epidermis staphylococus
US5097020A (en) * 1983-07-05 1992-03-17 The University Of Rochester Immunogenic conjugates
FR2619122B1 (fr) * 1987-08-03 1990-03-09 Pasteur Institut Procede d'obtention de polyosides capsulaires de staphylocoques, polyosides obtenus, applications de ces polyosides et souches pour la mise en oeuvre du procede
US5055455A (en) * 1988-09-28 1991-10-08 Brigham And Women's Hospital Capsular polysaccharide adhesin antigen, preparation, purification and use
US5571511A (en) * 1990-10-22 1996-11-05 The U.S. Government Broadly reactive opsonic antibodies that react with common staphylococcal antigens

Also Published As

Publication number Publication date
AU681573B2 (en) 1997-09-04
NO941877D0 (no) 1994-05-19
JP4353789B2 (ja) 2009-10-28
ES2198405T3 (es) 2004-02-01
US5961975A (en) 1999-10-05
FI942359A0 (fi) 1994-05-20
JP2004155789A (ja) 2004-06-03
DK0648127T3 (da) 2003-05-19
EP0648127A1 (de) 1995-04-19
CA2123811C (en) 2005-07-05
JPH07508498A (ja) 1995-09-21
FI111336B (fi) 2003-07-15
AU3074792A (en) 1993-06-15
WO1993009811A1 (en) 1993-05-27
NO319013B1 (no) 2005-06-06
CA2123811A1 (en) 1993-05-27
NO941877L (no) 1994-06-16
EP0648127A4 (de) 1995-06-14
US5866140A (en) 1999-02-02
FI942359A (fi) 1994-05-20
JP4087896B2 (ja) 2008-05-21
EP0648127B1 (de) 2003-04-16
DE69233012D1 (de) 2003-05-22
ATE237351T1 (de) 2003-05-15

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Legal Events

Date Code Title Description
8327 Change in the person/name/address of the patent owner

Owner name: NABI BIOPHARMACUTICALS, ROCKVILLE, MD, US

Owner name: FATTOM, ALI IBRAHIM, ROCKVILLE, MD., US

Owner name: WRIGHT, D.CRAIG, GAITHERSBURG, MD., US

8364 No opposition during term of opposition