DK0473671T3 - Anvendelse af sigma-receptorligander til fremstilling af et anxiolytisk middel - Google Patents
Anvendelse af sigma-receptorligander til fremstilling af et anxiolytisk middelInfo
- Publication number
- DK0473671T3 DK0473671T3 DK90908385.9T DK90908385T DK0473671T3 DK 0473671 T3 DK0473671 T3 DK 0473671T3 DK 90908385 T DK90908385 T DK 90908385T DK 0473671 T3 DK0473671 T3 DK 0473671T3
- Authority
- DK
- Denmark
- Prior art keywords
- prepare
- sigma receptor
- receptor ligands
- anxiolytic agent
- anxiolytic
- Prior art date
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/13—Amines
- A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/20—Hypnotics; Sedatives
Landscapes
- Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Neurosurgery (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Organic Chemistry (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Neurology (AREA)
- Biomedical Technology (AREA)
- General Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- Anesthesiology (AREA)
- Epidemiology (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Steroid Compounds (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US34649489A | 1989-05-02 | 1989-05-02 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0473671T3 true DK0473671T3 (da) | 1994-09-19 |
Family
ID=23359655
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90908385.9T DK0473671T3 (da) | 1989-05-02 | 1990-05-02 | Anvendelse af sigma-receptorligander til fremstilling af et anxiolytisk middel |
Country Status (9)
Country | Link |
---|---|
EP (1) | EP0473671B1 (de) |
JP (1) | JPH05500798A (de) |
AT (1) | ATE110265T1 (de) |
AU (1) | AU642881B2 (de) |
CA (1) | CA2054211A1 (de) |
DE (1) | DE69011859T2 (de) |
DK (1) | DK0473671T3 (de) |
ES (1) | ES2057568T3 (de) |
WO (1) | WO1990014067A2 (de) |
Families Citing this family (29)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5312840A (en) * | 1986-07-10 | 1994-05-17 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education | Substituted guanidines having high binding to the sigma receptor and the use thereof |
US5502255A (en) * | 1986-07-10 | 1996-03-26 | State Of Oregon Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Substituted guanidines having high binding to the sigma receptor and the use thereof |
US5262568A (en) * | 1990-03-02 | 1993-11-16 | State Of Oregon | Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists |
DK0517852T3 (da) | 1990-03-02 | 2002-10-07 | Oregon State | Tri- og tetrasubstituerede guanidinerog disses anvendelse som excitatoriske aminosyre-antagonister |
EP0532642A1 (de) * | 1990-05-25 | 1993-03-24 | STATE OF OREGON, acting through OREGON STATE BOARD OF HIGHER EDUCATION, acting for OREGON HEALTH SC. UNIV. AND UNIV. OF OREGON | Substituierte guanidine, welche eine hohe sigma-rezeptor-bindungsaffinität besitzen, und ihre verwendung |
US5847006A (en) * | 1991-02-08 | 1998-12-08 | Cambridge Neuroscience, Inc. | Therapeutic guanidines |
US5741661A (en) * | 1991-02-08 | 1998-04-21 | Cambridge Neuroscience, Inc. | Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers |
US5403861A (en) * | 1991-02-08 | 1995-04-04 | Cambridge Neuroscience, Inc. | Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers |
NZ243065A (en) * | 1991-06-13 | 1995-07-26 | Lundbeck & Co As H | Piperidine derivatives and pharmaceutical compositions |
DK78692D0 (da) * | 1992-06-12 | 1992-06-12 | Lundbeck & Co As H | Dimere piperidin- og piperazinderivater |
KR20030097618A (ko) * | 1993-05-27 | 2003-12-31 | 캠브리지 뉴로사이언스, 인코포레이티드 | 치료용 치환 구아니딘류 |
EP0746316A4 (de) * | 1993-11-22 | 1997-12-10 | Cambridge Neuroscience Inc | Guanidine zur therapeutischen anwendung |
WO1995014461A1 (en) * | 1993-11-23 | 1995-06-01 | Cambridge Neuroscience, Inc. | Therapeutic substituted guanidines |
US7351743B1 (en) | 1994-02-03 | 2008-04-01 | Wyeth | Therapeutic guanidines |
US6787569B1 (en) | 1994-02-03 | 2004-09-07 | Cambridge Neuroscience, Inc. | Therapeutic guanidines |
US6143791A (en) * | 1994-02-03 | 2000-11-07 | Cambridge Neuroscience, Inc. | Therapeutic guanidines |
CA2182302A1 (en) | 1994-02-03 | 1995-08-10 | Stanley M. Goldin | Therapeutic guanidines |
WO1995023132A1 (en) * | 1994-02-23 | 1995-08-31 | Cambridge Neuroscience, Inc. | Blockers of ion channels and methods of use thereof |
US6875759B1 (en) | 1999-07-21 | 2005-04-05 | Kadmus Pharmaceuticals | Substituted guanidines and the use thereof |
EP1749824A1 (de) | 2005-08-03 | 2007-02-07 | Neuro3D | Benzodiazepinederivate, Herstellung und Verwendung als Arzneimittel |
WO2007022964A2 (de) | 2005-08-24 | 2007-03-01 | Abbott Gmbh & Co. Kg | Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren |
EP2377530A3 (de) | 2005-10-21 | 2012-06-20 | Braincells, Inc. | Modulation von Neurogenese durch PDE-Hemmung |
WO2007053596A1 (en) | 2005-10-31 | 2007-05-10 | Braincells, Inc. | Gaba receptor mediated modulation of neurogenesis |
US20100216734A1 (en) | 2006-03-08 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis by nootropic agents |
JP2009536669A (ja) | 2006-05-09 | 2009-10-15 | ブレインセルス,インコーポレイティド | アンジオテンシン調節による神経新生 |
US20100184806A1 (en) | 2006-09-19 | 2010-07-22 | Braincells, Inc. | Modulation of neurogenesis by ppar agents |
US20100216805A1 (en) | 2009-02-25 | 2010-08-26 | Braincells, Inc. | Modulation of neurogenesis using d-cycloserine combinations |
JP6397407B2 (ja) * | 2012-07-19 | 2018-09-26 | ドレクセル ユニバーシティ | 細胞タンパク質ホメオスタシスを調節するためのシグマ受容体リガンド |
US11117870B2 (en) | 2017-11-01 | 2021-09-14 | Drexel University | Compounds, compositions, and methods for treating diseases |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4709094A (en) * | 1986-07-10 | 1987-11-24 | State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon | Sigma brain receptor ligands and their use |
-
1990
- 1990-05-02 DE DE69011859T patent/DE69011859T2/de not_active Expired - Fee Related
- 1990-05-02 AU AU57287/90A patent/AU642881B2/en not_active Ceased
- 1990-05-02 EP EP90908385A patent/EP0473671B1/de not_active Expired - Lifetime
- 1990-05-02 JP JP2508151A patent/JPH05500798A/ja active Pending
- 1990-05-02 AT AT90908385T patent/ATE110265T1/de not_active IP Right Cessation
- 1990-05-02 WO PCT/US1990/002398 patent/WO1990014067A2/en active IP Right Grant
- 1990-05-02 CA CA002054211A patent/CA2054211A1/en not_active Abandoned
- 1990-05-02 DK DK90908385.9T patent/DK0473671T3/da active
- 1990-05-02 ES ES90908385T patent/ES2057568T3/es not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
DE69011859D1 (de) | 1994-09-29 |
DE69011859T2 (de) | 1994-12-15 |
ATE110265T1 (de) | 1994-09-15 |
ES2057568T3 (es) | 1994-10-16 |
CA2054211A1 (en) | 1990-11-03 |
EP0473671A1 (de) | 1992-03-11 |
AU642881B2 (en) | 1993-11-04 |
EP0473671B1 (de) | 1994-08-24 |
AU5728790A (en) | 1990-12-18 |
WO1990014067A2 (en) | 1990-11-29 |
JPH05500798A (ja) | 1993-02-18 |
WO1990014067A3 (en) | 1991-04-04 |
EP0473671A4 (en) | 1992-04-01 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0473671T3 (da) | Anvendelse af sigma-receptorligander til fremstilling af et anxiolytisk middel | |
MX9101637A (es) | Herbicidas de aril-halogenoalquilpirazoles substituidos | |
BR0012243A (pt) | Triflúor butenos nematocidas | |
NO952494L (no) | Nytt protein fra urin med betegnelse komponent B | |
ES521422A0 (es) | Procedimiento para la obtencion de derivados de carboxilamida n-glicosilados. | |
DK0415613T3 (da) | Anvendelse af sertralin til behandling af præmatur ejakulation | |
ES2059121T5 (es) | Uso de agentes sensibilizantes de la insulina para tratar la hipertension. | |
LV10449A (lv) | Jauni hromana un tiohromana atvasinajumi | |
DK261490D0 (da) | New pharmaceutical compound | |
FI972703A (fi) | Rekombinantti IL-5-antagonisteja, jotka ovat käyttökelpoisia hoidettaessa IL-5:een liittyviä sairauksia | |
DK455088D0 (da) | Syntetiske receptoranaloger | |
DK0471718T3 (da) | Paracetamolholdigt farmaceutisk præparat | |
ES2076141T3 (es) | 5-aril-3h-1,2,4-triazol-3-onas y su uso como anticonvulsivos. | |
SE8700156D0 (sv) | Kosmetiska kompositioner med hudlugnande och hudgenerande effekt och forfarande for framstellning derav | |
DE59207900D1 (de) | Iloprost mit wirkung gegen cerebrale malaria | |
DE68913995D1 (de) | Zusammensetzung zur behandlung progressiver myopie. | |
ES2096559T3 (es) | Interferon gamma humano, procedimiento para la preparacion de dicho interferon gamma humano, y su uso. | |
DE3669159D1 (de) | Triazinderivate, verfahren zur herstellung dieser derivate und herbizide, welche diese derivate als wirksame komponente enthalten. | |
ES2051953T3 (es) | Derivados isomeros de trimetilbiciclo(4,3,0)nonano. | |
DK134982A (da) | Fremgangsmaade til fremstilling af guanidinopyrimidiner | |
SE9501773D0 (sv) | New use | |
ES1013934Y (es) | Pata perfeccionada para mesas de billar. | |
ES1014611Y (es) | Pata perfeccionada para mesas. | |
ES2025787T3 (es) | Procedimiento de tratamiento de madera. | |
MX9202927A (es) | [7-(3-amino disubstituidas)fenil]pirazolo[1,5-a]pirimidinas composicion farmaceutica que las contiene. |