ES2057568T3 - Metodos para tratar la ansiedad con ligandos de receptores sigma. - Google Patents

Metodos para tratar la ansiedad con ligandos de receptores sigma.

Info

Publication number
ES2057568T3
ES2057568T3 ES90908385T ES90908385T ES2057568T3 ES 2057568 T3 ES2057568 T3 ES 2057568T3 ES 90908385 T ES90908385 T ES 90908385T ES 90908385 T ES90908385 T ES 90908385T ES 2057568 T3 ES2057568 T3 ES 2057568T3
Authority
ES
Spain
Prior art keywords
anxiety
deal
methods
receiver links
sigma receiver
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES90908385T
Other languages
English (en)
Inventor
John F W Keana
Eckard Weber
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
State Of Oregon By & Through O
University of Oregon
Original Assignee
State Of Oregon By & Through O
University of Oregon
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by State Of Oregon By & Through O, University of Oregon filed Critical State Of Oregon By & Through O
Application granted granted Critical
Publication of ES2057568T3 publication Critical patent/ES2057568T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/13—Amines
    • A61K31/155—Amidines (), e.g. guanidine (H2N—C(=NH)—NH2), isourea (N=C(OH)—NH2), isothiourea (—N=C(SH)—NH2)
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives

Landscapes

  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Neurology (AREA)
  • Biomedical Technology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Anesthesiology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Steroid Compounds (AREA)

Abstract

LA INVENCION SE REFIERE A UN METODO PARA EL TRATAMIENTO O PROFILAXIS DE LA ANSIEDAD DE ANIMALES QUE CONSISTE EN ADMINISTRAR UNA CANTIDAD ANXIOLITICA DE UNA GUANIDINA N,N''-DISUSTITUIDA QUE TIENE UNA GRAN AFINIDAD CON EL RECEPTOR DE SIGMA.
ES90908385T 1989-05-02 1990-05-02 Metodos para tratar la ansiedad con ligandos de receptores sigma. Expired - Lifetime ES2057568T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US34649489A 1989-05-02 1989-05-02

Publications (1)

Publication Number Publication Date
ES2057568T3 true ES2057568T3 (es) 1994-10-16

Family

ID=23359655

Family Applications (1)

Application Number Title Priority Date Filing Date
ES90908385T Expired - Lifetime ES2057568T3 (es) 1989-05-02 1990-05-02 Metodos para tratar la ansiedad con ligandos de receptores sigma.

Country Status (9)

Country Link
EP (1) EP0473671B1 (es)
JP (1) JPH05500798A (es)
AT (1) ATE110265T1 (es)
AU (1) AU642881B2 (es)
CA (1) CA2054211A1 (es)
DE (1) DE69011859T2 (es)
DK (1) DK0473671T3 (es)
ES (1) ES2057568T3 (es)
WO (1) WO1990014067A2 (es)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5312840A (en) * 1986-07-10 1994-05-17 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education Substituted guanidines having high binding to the sigma receptor and the use thereof
US5502255A (en) * 1986-07-10 1996-03-26 State Of Oregon Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Substituted guanidines having high binding to the sigma receptor and the use thereof
US5262568A (en) * 1990-03-02 1993-11-16 State Of Oregon Tri- and tetra-substituted guanidines and their use as excitatory amino acid antagonists
DK0517852T3 (da) 1990-03-02 2002-10-07 Oregon State Tri- og tetrasubstituerede guanidinerog disses anvendelse som excitatoriske aminosyre-antagonister
EP0532642A1 (en) * 1990-05-25 1993-03-24 STATE OF OREGON, acting through OREGON STATE BOARD OF HIGHER EDUCATION, acting for OREGON HEALTH SC. UNIV. AND UNIV. OF OREGON Substituted guanidines having high binding to the sigma receptor and the use thereof
US5847006A (en) * 1991-02-08 1998-12-08 Cambridge Neuroscience, Inc. Therapeutic guanidines
US5741661A (en) * 1991-02-08 1998-04-21 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
US5403861A (en) * 1991-02-08 1995-04-04 Cambridge Neuroscience, Inc. Substituted guanidines and derivatives thereof as modulators of neurotransmitter release and novel methodology for identifying neurotransmitter release blockers
NZ243065A (en) * 1991-06-13 1995-07-26 Lundbeck & Co As H Piperidine derivatives and pharmaceutical compositions
DK78692D0 (da) * 1992-06-12 1992-06-12 Lundbeck & Co As H Dimere piperidin- og piperazinderivater
KR20030097618A (ko) * 1993-05-27 2003-12-31 캠브리지 뉴로사이언스, 인코포레이티드 치료용 치환 구아니딘류
EP0746316A4 (en) * 1993-11-22 1997-12-10 Cambridge Neuroscience Inc GUANIDINE FOR THERAPEUTIC USE
WO1995014461A1 (en) * 1993-11-23 1995-06-01 Cambridge Neuroscience, Inc. Therapeutic substituted guanidines
US7351743B1 (en) 1994-02-03 2008-04-01 Wyeth Therapeutic guanidines
US6787569B1 (en) 1994-02-03 2004-09-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
US6143791A (en) * 1994-02-03 2000-11-07 Cambridge Neuroscience, Inc. Therapeutic guanidines
CA2182302A1 (en) 1994-02-03 1995-08-10 Stanley M. Goldin Therapeutic guanidines
WO1995023132A1 (en) * 1994-02-23 1995-08-31 Cambridge Neuroscience, Inc. Blockers of ion channels and methods of use thereof
US6875759B1 (en) 1999-07-21 2005-04-05 Kadmus Pharmaceuticals Substituted guanidines and the use thereof
EP1749824A1 (en) 2005-08-03 2007-02-07 Neuro3D Benzodiazepine derivatives, their preparation and the therapeutic use thereof
WO2007022964A2 (de) 2005-08-24 2007-03-01 Abbott Gmbh & Co. Kg Hetaryl substituierte guanidinverbindungen und ihre verwendung als bindungspartner für 5-ht5-rezeptoren
EP2377530A3 (en) 2005-10-21 2012-06-20 Braincells, Inc. Modulation of neurogenesis by PDE inhibition
WO2007053596A1 (en) 2005-10-31 2007-05-10 Braincells, Inc. Gaba receptor mediated modulation of neurogenesis
US20100216734A1 (en) 2006-03-08 2010-08-26 Braincells, Inc. Modulation of neurogenesis by nootropic agents
JP2009536669A (ja) 2006-05-09 2009-10-15 ブレインセルス，インコーポレイティド アンジオテンシン調節による神経新生
US20100184806A1 (en) 2006-09-19 2010-07-22 Braincells, Inc. Modulation of neurogenesis by ppar agents
US20100216805A1 (en) 2009-02-25 2010-08-26 Braincells, Inc. Modulation of neurogenesis using d-cycloserine combinations
JP6397407B2 (ja) * 2012-07-19 2018-09-26 ドレクセル ユニバーシティ 細胞タンパク質ホメオスタシスを調節するためのシグマ受容体リガンド
US11117870B2 (en) 2017-11-01 2021-09-14 Drexel University Compounds, compositions, and methods for treating diseases

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4709094A (en) * 1986-07-10 1987-11-24 State Of Oregon, Acting By And Through The Oregon State Board Of Higher Education, Acting For And On Behalf Of The Oregon Health Sciences University And The University Of Oregon Sigma brain receptor ligands and their use

Also Published As

Publication number Publication date
DK0473671T3 (da) 1994-09-19
DE69011859D1 (de) 1994-09-29
DE69011859T2 (de) 1994-12-15
ATE110265T1 (de) 1994-09-15
CA2054211A1 (en) 1990-11-03
EP0473671A1 (en) 1992-03-11
AU642881B2 (en) 1993-11-04
EP0473671B1 (en) 1994-08-24
AU5728790A (en) 1990-12-18
WO1990014067A2 (en) 1990-11-29
JPH05500798A (ja) 1993-02-18
WO1990014067A3 (en) 1991-04-04
EP0473671A4 (en) 1992-04-01

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