DK0464325T3 - Fremgangsmåde til fremstilling af salte af L-ornithin - Google Patents

Fremgangsmåde til fremstilling af salte af L-ornithin

Info

Publication number
DK0464325T3
DK0464325T3 DK91105851.9T DK91105851T DK0464325T3 DK 0464325 T3 DK0464325 T3 DK 0464325T3 DK 91105851 T DK91105851 T DK 91105851T DK 0464325 T3 DK0464325 T3 DK 0464325T3
Authority
DK
Denmark
Prior art keywords
ornithine
salts
preparation
prepared
reaction mixture
Prior art date
Application number
DK91105851.9T
Other languages
English (en)
Inventor
Karlheinz Dr Drauz
Kyriakos Dr Makryaleas
Original Assignee
Degussa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Degussa filed Critical Degussa
Application granted granted Critical
Publication of DK0464325T3 publication Critical patent/DK0464325T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P13/00—Preparation of nitrogen-containing organic compounds
    • C12P13/04—Alpha- or beta- amino acids
    • C12P13/10—Citrulline; Arginine; Ornithine

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Wood Science & Technology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Microbiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Biotechnology (AREA)
  • Health & Medical Sciences (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Separation Using Semi-Permeable Membranes (AREA)
DK91105851.9T 1990-07-02 1991-04-12 Fremgangsmåde til fremstilling af salte af L-ornithin DK0464325T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE4020980A DE4020980C1 (da) 1990-07-02 1990-07-02

Publications (1)

Publication Number Publication Date
DK0464325T3 true DK0464325T3 (da) 1995-11-27

Family

ID=6409473

Family Applications (1)

Application Number Title Priority Date Filing Date
DK91105851.9T DK0464325T3 (da) 1990-07-02 1991-04-12 Fremgangsmåde til fremstilling af salte af L-ornithin

Country Status (7)

Country Link
US (1) US5405761A (da)
EP (1) EP0464325B1 (da)
JP (1) JPH04229184A (da)
AT (1) ATE126829T1 (da)
DE (2) DE4020980C1 (da)
DK (1) DK0464325T3 (da)
ES (1) ES2076398T3 (da)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5591613A (en) * 1990-07-02 1997-01-07 Degussa Aktiengesellschaft Method for the preparation of D-arginine and L-ornithine
DE4119029A1 (de) * 1991-06-10 1992-12-17 Degussa Stabilisierte, metallionenaktivierte l-arginase (l-arginin amidinohydrolase
JP4042397B2 (ja) * 2001-11-07 2008-02-06 ひかり製菓株式会社 呈味改良剤
WO2006001345A1 (ja) * 2004-06-23 2006-01-05 Kyowa Hakko Kogyo Co., Ltd. Ｌ－リジン・クエン酸塩結晶
EP1767521B1 (en) * 2004-06-25 2014-04-23 Kyowa Hakko Bio Co., Ltd. L-ornithine-citric acid salt crystal
EP2319581B1 (en) 2004-11-26 2015-02-25 UCL Business PLC Compositions comprising ornithine and phenylacetate or phenylbutyrate for treating hepatic encephalopathy
CN1322139C (zh) * 2004-12-15 2007-06-20 南京大学 固定化细胞酶法制备l－鸟氨酸的方法
CN101851646B (zh) * 2009-03-31 2013-11-27 上海汉飞生化科技有限公司 一种固定化酶法生产l-鸟氨酸盐酸盐的方法
WO2010115055A1 (en) 2009-04-03 2010-10-07 Ocera Therapeutics, Inc. L-ornithine phenyl acetate and methods of making thereof
AU2010258888B2 (en) 2009-06-08 2014-08-07 Ocera Therapeutics, Inc. Treatment of portal hypertension and restoration of liver function using L-ornithine phenylacetate
EA028395B1 (ru) 2010-10-06 2017-11-30 Осера Терапьютикс, Инк. Способы получения фенилацетата l-орнитина
CN102863346B (zh) * 2012-09-07 2014-12-31 宜兴市前成生物有限公司 一种制备l-天门冬氨酸-l-鸟氨酸的方法
BR112017010761B1 (pt) 2014-11-24 2022-10-18 Ucl Business Plc Tratamento de doenças associadas à ativação de célula estrelada hepática com o uso de terapias de redução de amônia
US10544435B2 (en) 2015-03-12 2020-01-28 Chrysea Limited L-ornithine production in eukaryotic cells
CN105175275B (zh) * 2015-07-01 2017-03-01 山东民强生物科技股份有限公司 一种l‑鸟氨酸的分离纯化方法
EP3337473A4 (en) 2015-08-18 2019-04-17 Ocera Therapeutics, Inc. TREATMENT AND PREVENTION OF MUSCLE WOUND BY L-ORNITHIN IN COMBINATION WITH AT LEAST ONE PHENYL ACETATE AND PHENYL BUTYRATE
CN106699586B (zh) * 2016-12-08 2019-01-25 陕西天宇制药有限公司 门冬氨酸鸟氨酸的制备方法
KR20200024145A (ko) 2017-05-11 2020-03-06 오세라 테라퓨틱스, 아이엔씨. L-오르니틴 페닐아세테이트의 제조방법
CN108440324B (zh) * 2018-04-19 2021-04-20 成都倍特药业股份有限公司 一种门冬氨酸鸟氨酸及其结晶方法
CN109651181A (zh) * 2018-12-29 2019-04-19 南通紫琅生物医药科技有限公司 一种l-鸟氨酸盐酸盐生产工艺
CN113372232B (zh) * 2021-06-04 2023-06-13 无锡晶海氨基酸股份有限公司 去除盐酸鸟氨酸中鸟氨酸内酰胺的方法

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2988489A (en) * 1957-09-19 1961-06-13 Kyowa Hakko Kogyo Kk Method of producing l-ornithine by fermentation
GB996544A (en) * 1962-07-14 1965-06-30 Ajinomoto Kk A process for producing amino acids
US3668072A (en) * 1969-01-02 1972-06-06 Chugai Pharmaceutical Co Ltd Fermentation process for the production of l-ornithine
US4248677A (en) * 1978-07-10 1981-02-03 Tokuyama Soda Kabushiki Kaisha Process for producing alpha-aminocarboxylic acids and salts thereof
DE2945790A1 (de) * 1978-11-20 1980-05-29 Tanabe Seiyaku Co Neutrales kristallines salz einer basischen l-aminosaeure mit l-apfelsaeure und verfahren zu dessen herstellung
US4346169A (en) * 1980-09-15 1982-08-24 Ajinomoto Company, Incorporated Method for production of L-arginine by fermentation
US4698442A (en) * 1982-12-21 1987-10-06 Syntex (U.S.A.) Inc. ω-Guanidino-substituted-α-amino acids
JPS62294069A (ja) * 1986-06-13 1987-12-21 Togo Kuroiwa Ｌ−オルニチンを高単位に含有した栄養補給液
US4882226A (en) * 1986-09-23 1989-11-21 Akzo N.V. Carrier material for use in chromatography or carrying out enzymatic reactions
US5059712A (en) * 1989-09-13 1991-10-22 Cornell Research Foundation, Inc. Isolating aminoarginine and use to block nitric oxide formation in body

Also Published As

Publication number Publication date
EP0464325A3 (en) 1992-04-08
ATE126829T1 (de) 1995-09-15
DE59106289D1 (de) 1995-09-28
DE4020980C1 (da) 1991-09-26
ES2076398T3 (es) 1995-11-01
JPH04229184A (ja) 1992-08-18
EP0464325B1 (de) 1995-08-23
EP0464325A2 (de) 1992-01-08
US5405761A (en) 1995-04-11

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