DK0451824T3 - Chelatdannende forbindelser og anvendelse deraf - Google Patents
Chelatdannende forbindelser og anvendelse derafInfo
- Publication number
- DK0451824T3 DK0451824T3 DK91105704.0T DK91105704T DK0451824T3 DK 0451824 T3 DK0451824 T3 DK 0451824T3 DK 91105704 T DK91105704 T DK 91105704T DK 0451824 T3 DK0451824 T3 DK 0451824T3
- Authority
- DK
- Denmark
- Prior art keywords
- ch2cooh
- integer
- hepatobiliary
- chelate
- chelating compound
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C311/00—Amides of sulfonic acids, i.e. compounds having singly-bound oxygen atoms of sulfo groups replaced by nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/30—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups
- C07C311/37—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring
- C07C311/38—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton
- C07C311/39—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom
- C07C311/41—Sulfonamides, the carbon skeleton of the acid part being further substituted by singly-bound nitrogen atoms, not being part of nitro or nitroso groups having the sulfur atom of at least one of the sulfonamide groups bound to a carbon atom of a six-membered aromatic ring having sulfur atoms of sulfonamide groups and amino groups bound to carbon atoms of six-membered rings of the same carbon skeleton having the nitrogen atom of at least one of the sulfonamide groups bound to hydrogen atoms or to an acyclic carbon atom to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms, not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K49/00—Preparations for testing in vivo
- A61K49/06—Nuclear magnetic resonance [NMR] contrast preparations; Magnetic resonance imaging [MRI] contrast preparations
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0474—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group
- A61K51/0478—Organic compounds complexes or complex-forming compounds, i.e. wherein a radioactive metal (e.g. 111In3+) is complexed or chelated by, e.g. a N2S2, N3S, NS3, N4 chelating group complexes from non-cyclic ligands, e.g. EDTA, MAG3
- A61K51/048—DTPA (diethylenetriamine tetraacetic acid)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K51/00—Preparations containing radioactive substances for use in therapy or testing in vivo
- A61K51/02—Preparations containing radioactive substances for use in therapy or testing in vivo characterised by the carrier, i.e. characterised by the agent or material covalently linked or complexing the radioactive nucleus
- A61K51/04—Organic compounds
- A61K51/0497—Organic compounds conjugates with a carrier being an organic compounds
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/06—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
- C07C237/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups
- C07C237/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton
- C07C237/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated
- C07C237/10—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by amino groups having the carbon atoms of the carboxamide groups bound to acyclic carbon atoms of the carbon skeleton the carbon skeleton being acyclic and saturated having the nitrogen atom of at least one of the carboxamide groups bound to an acyclic carbon atom of a hydrocarbon radical substituted by nitrogen atoms not being part of nitro or nitroso groups
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K2123/00—Preparations for testing in vivo
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmacology & Pharmacy (AREA)
- Medicinal Chemistry (AREA)
- Epidemiology (AREA)
- Physics & Mathematics (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Optics & Photonics (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- Radiology & Medical Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Gastroenterology & Hepatology (AREA)
- Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Magnetic Resonance Imaging Apparatus (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP2094353A JP2776953B2 (ja) | 1990-04-10 | 1990-04-10 | 多官能性金属キレート化合物とその用途 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0451824T3 true DK0451824T3 (da) | 1996-03-11 |
Family
ID=14107923
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK91105704.0T DK0451824T3 (da) | 1990-04-10 | 1991-04-10 | Chelatdannende forbindelser og anvendelse deraf |
Country Status (10)
Country | Link |
---|---|
US (2) | US5196576A (ko) |
EP (1) | EP0451824B1 (ko) |
JP (1) | JP2776953B2 (ko) |
KR (1) | KR100189388B1 (ko) |
AT (1) | ATE134190T1 (ko) |
AU (1) | AU634645B2 (ko) |
CA (1) | CA2040204C (ko) |
DE (1) | DE69117084T2 (ko) |
DK (1) | DK0451824T3 (ko) |
ES (1) | ES2085924T3 (ko) |
Families Citing this family (23)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP2807852B2 (ja) * | 1991-07-18 | 1998-10-08 | 株式会社ミドリ十字 | 新規キレート化剤、該キレート化剤と金属原子との錯化合物及びそれを含む診断剤 |
TW213864B (ko) * | 1991-08-01 | 1993-10-01 | Squibb & Sons Inc | |
US5541287A (en) * | 1992-06-09 | 1996-07-30 | Neorx Corporation | Pretargeting methods and compounds |
US6358490B2 (en) | 1992-06-09 | 2002-03-19 | Neorx Corporation | Three-step pretargeting methods and compounds |
EP1138334A3 (en) * | 1992-06-09 | 2002-04-03 | Neorx Corporation | Pretargeting methods and compounds |
US6022966A (en) * | 1993-11-22 | 2000-02-08 | Neorx Corporation | Pretargeting methods and compounds |
US5911969A (en) | 1992-06-09 | 1999-06-15 | Neorx Corporation | Pretargeting protocols for enhanced localization of active agents to target sites |
US5578287A (en) * | 1992-06-09 | 1996-11-26 | Neorx Corporation | Three-step pretargeting methods using improved biotin-active agent |
CA2116867C (en) * | 1992-07-03 | 2004-04-27 | The Green Cross Corporation | Novel chelating agent, complex compound of said chelating agent and metallic atom, and diagnostic agent comprising same |
EP0955066A3 (en) * | 1992-07-31 | 2002-08-28 | Australian Nuclear Science And Technology Organisation | Metal complexes of hydroxyaryl containing aminocarboxylic acid chelating agents |
US5807535A (en) * | 1992-07-31 | 1998-09-15 | Australian Nuclear Science & Technology Organisation | Metal complexes of hydroxyaryl containing aminocarboxylic acid chelating agents |
US6908903B1 (en) | 1994-12-07 | 2005-06-21 | Aletheon Pharmaceuticals, Inc. | Cluster clearing agents |
US6172045B1 (en) | 1994-12-07 | 2001-01-09 | Neorx Corporation | Cluster clearing agents |
US5955605A (en) * | 1995-02-21 | 1999-09-21 | Neorx Corporation | Biotinidase resistant biotin-DOTA conjugates |
EP1033471B1 (en) * | 1999-03-02 | 2003-09-17 | Rohm And Haas Company | Improved recovery and transportation of heavy crude oils |
DE10002939C1 (de) * | 2000-01-13 | 2001-09-20 | Schering Ag | Paramagnetische DOTA-Derivate, Verfahren zu ihrer Herstellung und ihre Verwendung für die Herstellung von pharmazeutischen Mitteln |
IL145210A (en) | 2000-12-06 | 2011-12-29 | Aposense Ltd | Materials that bind shaken membranes |
IL147812A0 (en) * | 2001-03-16 | 2002-08-14 | N S T Neurosurvival Technologi | Method for targeting chemical compounds to cells and pharmaceutical compositions used therein |
IL153183A (en) * | 2002-06-04 | 2010-05-17 | Aposense Ltd | Agents for imaging and diagnostic methods using them |
WO2004075925A1 (ja) * | 2003-02-27 | 2004-09-10 | Kyushu Tlo Company Limited | Mri用造影剤 |
AU2005280455A1 (en) * | 2004-08-26 | 2006-03-09 | Mallinckrodt Inc. | Luminescent metal complexes for monitoring renal function |
KR101522963B1 (ko) | 2007-11-12 | 2015-05-26 | 산요덴키가부시키가이샤 | 비수 전해질 2차전지 부극재, 비수 전해질 2차전지용 부극 및 비수 전해질 2차전지, 및 비수 전해질 2차전지 부극재의 활물질용 다결정 규소 입자의 제조방법 |
WO2015097990A1 (ja) | 2013-12-25 | 2015-07-02 | 信越化学工業株式会社 | 非水電解質二次電池用負極活物質及びその製造方法 |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH607920A5 (ko) * | 1976-05-31 | 1978-12-15 | Solco Basel Ag | |
US4352751A (en) * | 1979-09-10 | 1982-10-05 | Analytical Radiation Corporation | Species-linked diamine triacetic acids and their chelates |
US4418208A (en) * | 1980-12-29 | 1983-11-29 | E. R. Squibb & Sons, Inc. | N-Substituted iminodiacetic acids |
US4957939A (en) * | 1981-07-24 | 1990-09-18 | Schering Aktiengesellschaft | Sterile pharmaceutical compositions of gadolinium chelates useful enhancing NMR imaging |
US4647447A (en) * | 1981-07-24 | 1987-03-03 | Schering Aktiengesellschaft | Diagnostic media |
JPS5828718A (ja) * | 1981-08-14 | 1983-02-19 | Toyo Contact Lens Co Ltd | ソフトコンタクトレンズ |
US4454107A (en) * | 1982-08-30 | 1984-06-12 | Merck & Co., Inc. | Tc99m-Phenida, radioscintigraphic agent for diagnosis of hepatoniliary disease |
US4943523A (en) * | 1984-01-30 | 1990-07-24 | Enzo Biochem, Inc. | Detectable molecules, method of preparation and use |
IL83966A (en) * | 1986-09-26 | 1992-03-29 | Schering Ag | Amides of aminopolycarboxylic acids and pharmaceutical compositions containing them |
US4843062A (en) * | 1987-12-23 | 1989-06-27 | American Home Products Corporation | N-acyl-N-napthoylglycines as aldose reductase inhibitors |
JP2815615B2 (ja) * | 1988-06-07 | 1998-10-27 | 日本メジフィジックス株式会社 | ジエチレントリアミン五酢酸誘導体とその用途 |
-
1990
- 1990-04-10 JP JP2094353A patent/JP2776953B2/ja not_active Expired - Fee Related
-
1991
- 1991-04-09 US US07/682,080 patent/US5196576A/en not_active Expired - Lifetime
- 1991-04-10 DE DE69117084T patent/DE69117084T2/de not_active Expired - Fee Related
- 1991-04-10 ES ES91105704T patent/ES2085924T3/es not_active Expired - Lifetime
- 1991-04-10 AU AU74281/91A patent/AU634645B2/en not_active Ceased
- 1991-04-10 AT AT91105704T patent/ATE134190T1/de not_active IP Right Cessation
- 1991-04-10 CA CA002040204A patent/CA2040204C/en not_active Expired - Fee Related
- 1991-04-10 KR KR1019910005737A patent/KR100189388B1/ko not_active IP Right Cessation
- 1991-04-10 DK DK91105704.0T patent/DK0451824T3/da active
- 1991-04-10 EP EP91105704A patent/EP0451824B1/en not_active Expired - Lifetime
- 1991-08-15 US US07/745,393 patent/US5138039A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
KR910018346A (ko) | 1991-11-30 |
US5196576A (en) | 1993-03-23 |
ATE134190T1 (de) | 1996-02-15 |
KR100189388B1 (ko) | 1999-06-01 |
ES2085924T3 (es) | 1996-06-16 |
JPH03291260A (ja) | 1991-12-20 |
EP0451824A3 (en) | 1992-09-02 |
EP0451824A2 (en) | 1991-10-16 |
JP2776953B2 (ja) | 1998-07-16 |
DE69117084D1 (de) | 1996-03-28 |
DE69117084T2 (de) | 1996-10-02 |
AU7428191A (en) | 1991-10-17 |
AU634645B2 (en) | 1993-02-25 |
CA2040204C (en) | 2002-07-02 |
US5138039A (en) | 1992-08-11 |
CA2040204A1 (en) | 1991-10-11 |
EP0451824B1 (en) | 1996-02-14 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
DK0451824T3 (da) | Chelatdannende forbindelser og anvendelse deraf | |
NO900192D0 (no) | Aminopolykarboksylsyrer og derivater derav. | |
FI935308A0 (fi) | Joderade aroyloxiestrar | |
SE8301395L (sv) | Kelatiserande foreningar med funktionella grupper vilka tillater kovalent koppling till bio-organiska molekyler | |
HUT47529A (en) | Process for producing polyethyleneglycol-carbaminates and diagnostic and pharmaceutical compositions comprising such compounds | |
ATE39483T1 (de) | Kondensierte pyrrolinon-derivate, und ihre herstellung. | |
KR970704864A (ko) | 세정제 조성물 | |
ATE69239T1 (de) | Oligopeptidylnitrilderivate, diese enthaltende mittel, verfahren zu ihrer herstellung und ihre verwendung. | |
MY115466A (en) | Substituted cinnamic acid guanidides, a process for their preparation, their use as medicaments or diagnostic agents and medicaments comprising them. | |
DK162045C (da) | Trijodbenzenderivater, fremgangsmaade til fremstilling deraf og radiologiske praeparater indeholdende saadanne forbindelser | |
DE69318711T2 (de) | Desferrioxamine-b salze und ihre verwendung als oral wirksame eisen- chelatbildner | |
GB1229082A (ko) | ||
GR77667B (ko) | ||
LV10234A (lv) | Trijodbenzola savienojumu iegusanas metode | |
DE69118520D1 (de) | Sechsbindige liganden für radiographische abbildungsagenzien | |
DK0517394T3 (da) | Præparat mod ondartet svinelungesyge | |
DK82583D0 (da) | Furyloxazolyleddikesyrederivater og fremgangsmader til fremstilling deraf | |
NZ192844A (en) | Thiazole derivatives and compositions | |
ATE86972T1 (de) | Verfahren zur herstellung von substituierten 3amino-2(benzoyl)-acrylsaeureestern sowie ein verfahren zur herstellung von zwischenprodukten fuer antibakterielle wirkstoffe aus diesen verbindungen. | |
ES467316A1 (es) | Procedimiento para la obtencion de derivados de acidos metil-2 fenoxi-2 propionicos. | |
SE7614473L (sv) | Nya aminer | |
IT1244649B (it) | Procedimento per il trattamento di substrati com composti aromatici contenenti gruppi solfo, composizioni contenenti tali composti e loro preparazione |