DK0414421T3 - 1-Oxa-2-oxo-8-azaspiro(4,5)decan-derivater, fremgangsmåder til deres fremstilling samt farmaceutiske præparater med indhold deraf - Google Patents

1-Oxa-2-oxo-8-azaspiro(4,5)decan-derivater, fremgangsmåder til deres fremstilling samt farmaceutiske præparater med indhold deraf

Info

Publication number
DK0414421T3
DK0414421T3 DK90308784.9T DK90308784T DK0414421T3 DK 0414421 T3 DK0414421 T3 DK 0414421T3 DK 90308784 T DK90308784 T DK 90308784T DK 0414421 T3 DK0414421 T3 DK 0414421T3
Authority
DK
Denmark
Prior art keywords
group
alkyl
halogen atoms
alkoxy
oxa
Prior art date
Application number
DK90308784.9T
Other languages
Danish (da)
English (en)
Inventor
Eva Dr Palosi
Laszlo Dr Szporny
Katalin Csomor
Dora Dr Groo
Istvan Dr Laszlovszky
Bela Kiss
Zsolt Dr Szombathelyi
Edit Toth
Jozsef Torley
Egon Dr Karpati
Adam Dr Sarkadi
Aniko Gere
Mihaly Dr Bodo
Judit Dr Laszy
Zsolt Szentirmay
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Application granted granted Critical
Publication of DK0414421T3 publication Critical patent/DK0414421T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biomedical Technology (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Diabetes (AREA)
  • Hospice & Palliative Care (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Psychiatry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Hydrogenated Pyridines (AREA)
DK90308784.9T 1989-08-10 1990-08-09 1-Oxa-2-oxo-8-azaspiro(4,5)decan-derivater, fremgangsmåder til deres fremstilling samt farmaceutiske præparater med indhold deraf DK0414421T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU894095A HU204530B (en) 1989-08-10 1989-08-10 Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them
SG96294A SG96294G (en) 1989-08-10 1994-07-16 1-oxa-2-oxo-8-azaspiro[4,5] decane derivatives, processes for their preparation and pharmaceutical compositions thereof

Publications (1)

Publication Number Publication Date
DK0414421T3 true DK0414421T3 (da) 1994-05-16

Family

ID=26317733

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90308784.9T DK0414421T3 (da) 1989-08-10 1990-08-09 1-Oxa-2-oxo-8-azaspiro(4,5)decan-derivater, fremgangsmåder til deres fremstilling samt farmaceutiske præparater med indhold deraf

Country Status (23)

Country Link
US (1) US5118687A (bg)
EP (1) EP0414421B1 (bg)
JP (1) JPH0749431B2 (bg)
KR (1) KR940006635B1 (bg)
AT (1) ATE103920T1 (bg)
AU (1) AU622039B2 (bg)
BG (1) BG60436B2 (bg)
DD (1) DD299429A5 (bg)
DE (1) DE69007904T2 (bg)
DK (1) DK0414421T3 (bg)
ES (1) ES2052180T3 (bg)
FI (1) FI93455C (bg)
HK (1) HK145994A (bg)
HR (1) HRP920778A2 (bg)
HU (2) HU204530B (bg)
IE (1) IE64911B1 (bg)
IL (1) IL95320A (bg)
NO (1) NO177962C (bg)
NZ (1) NZ234848A (bg)
PL (3) PL163593B1 (bg)
SG (1) SG96294G (bg)
SI (1) SI9011538A (bg)
ZA (1) ZA906302B (bg)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
YU150489A (sh) * 1989-08-10 1992-12-21 W.L. Gore & Co. Gmbh. Uređaj za ispitivanje odevnih predmeta na nepromočivost
EP2286847A1 (en) * 1999-10-15 2011-02-23 Genetics Institute, LLC Formulations of hyaluronic acid for delivery of osteogenic proteins
KR20020091462A (ko) * 2001-05-30 2002-12-06 삼성광주전자 주식회사 원료 굳음 방지기능을 갖는 자동판매기 및 그 제어방법
GB201416346D0 (en) * 2014-09-16 2014-10-29 Shire Internat Gmbh Spirocyclic derivatives

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR96352E (fr) * 1967-12-29 1972-06-16 Science Union & Cie Nouveaux dérives du spiro (4,5) decane et leur procédé de préparation.
BE790675A (fr) * 1971-10-29 1973-04-27 Science Union & Cie Nouveaux derives de l'oxa-1 diaza-3,8 spiro (4,5) decane
EP0189370A3 (de) * 1985-01-16 1988-01-27 Sandoz Ag Spiro-dioxolane, -dithiolane und -oxothiolane
KR940003491B1 (ko) * 1989-08-10 1994-04-23 리히터 게데온 베기에스제티 기아르 알.티 4,4-이중 치환된 피페리딘 유도체와 그 제조방법 및 상기 화합물을 함유하는 약제학적 조성물
HU204529B (en) * 1989-08-10 1992-01-28 Richter Gedeon Vegyeszet Process for producing new 1-oxa-2-oxo-8-aza-spiro(4,5)decane derivatives and pharmaceutical compositions containing them

Also Published As

Publication number Publication date
EP0414421B1 (en) 1994-04-06
DE69007904D1 (de) 1994-05-11
DE69007904T2 (de) 1994-07-21
JPH0377884A (ja) 1991-04-03
PL286440A1 (en) 1992-01-27
IL95320A0 (en) 1991-06-30
ATE103920T1 (de) 1994-04-15
JPH0749431B2 (ja) 1995-05-31
IE902884A1 (en) 1991-02-27
HK145994A (en) 1994-12-30
SI9011538A (sl) 1998-08-31
BG60436B2 (bg) 1995-03-31
NO177962B (no) 1995-09-18
ES2052180T3 (es) 1994-07-01
KR940006635B1 (ko) 1994-07-23
AU6080790A (en) 1991-02-14
FI93455B (fi) 1994-12-30
FI903972A0 (fi) 1990-08-10
KR910004632A (ko) 1991-03-29
SG96294G (en) 1994-10-28
EP0414421A3 (en) 1991-07-24
IE64911B1 (en) 1995-09-20
ZA906302B (en) 1991-06-26
PL163370B1 (pl) 1994-03-31
IL95320A (en) 1994-01-25
FI93455C (fi) 1995-04-10
NO903512L (no) 1991-02-11
NZ234848A (en) 1992-03-26
DD299429A5 (de) 1992-04-16
HRP920778A2 (en) 1998-02-28
HUT55786A (en) 1991-06-28
HU204530B (en) 1992-01-28
NO177962C (no) 1995-12-27
NO903512D0 (no) 1990-08-09
US5118687A (en) 1992-06-02
HU210072A9 (en) 1995-02-28
PL163593B1 (en) 1994-04-29
EP0414421A2 (en) 1991-02-27
PL163431B1 (pl) 1994-03-31
PL291701A1 (en) 1992-05-04
PL291702A1 (en) 1992-05-04
AU622039B2 (en) 1992-03-26

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