DK0414178T3 - Ikke-humane primat-CD4-polypeptider og humane CD4-molekyler, som kan glycosyleres - Google Patents

Ikke-humane primat-CD4-polypeptider og humane CD4-molekyler, som kan glycosyleres

Info

Publication number
DK0414178T3
DK0414178T3 DK90115877.4T DK90115877T DK0414178T3 DK 0414178 T3 DK0414178 T3 DK 0414178T3 DK 90115877 T DK90115877 T DK 90115877T DK 0414178 T3 DK0414178 T3 DK 0414178T3
Authority
DK
Denmark
Prior art keywords
molecules
relates
fusion proteins
immunoglobulin
fragments
Prior art date
Application number
DK90115877.4T
Other languages
Danish (da)
English (en)
Inventor
Brian Seed
David Camerini
Original Assignee
Gen Hospital Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gen Hospital Corp filed Critical Gen Hospital Corp
Application granted granted Critical
Publication of DK0414178T3 publication Critical patent/DK0414178T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70503—Immunoglobulin superfamily
    • C07K14/70514—CD4
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/33—Fusion polypeptide fusions for targeting to specific cell types, e.g. tissue specific targeting, targeting of a bacterial subspecies

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Immunology (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Cell Biology (AREA)
  • Toxicology (AREA)
  • Zoology (AREA)
  • Gastroenterology & Hepatology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Oncology (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Communicable Diseases (AREA)
  • Virology (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
DK90115877.4T 1989-08-23 1990-08-18 Ikke-humane primat-CD4-polypeptider og humane CD4-molekyler, som kan glycosyleres DK0414178T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US39778289A 1989-08-23 1989-08-23

Publications (1)

Publication Number Publication Date
DK0414178T3 true DK0414178T3 (da) 1997-05-26

Family

ID=23572610

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90115877.4T DK0414178T3 (da) 1989-08-23 1990-08-18 Ikke-humane primat-CD4-polypeptider og humane CD4-molekyler, som kan glycosyleres

Country Status (16)

Country Link
US (1) US5420264A (de)
EP (1) EP0414178B1 (de)
JP (1) JPH05500611A (de)
KR (1) KR927003613A (de)
AT (1) ATE145938T1 (de)
AU (1) AU648041B2 (de)
CA (1) CA2065010A1 (de)
DE (1) DE69029294T2 (de)
DK (1) DK0414178T3 (de)
ES (1) ES2097121T3 (de)
FI (1) FI920658A0 (de)
GR (1) GR3022039T3 (de)
IE (1) IE903043A1 (de)
PT (1) PT95072A (de)
WO (1) WO1991002743A1 (de)
ZA (1) ZA906246B (de)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5225538A (en) * 1989-02-23 1993-07-06 Genentech, Inc. Lymphocyte homing receptor/immunoglobulin fusion proteins
US6406697B1 (en) 1989-02-23 2002-06-18 Genentech, Inc. Hybrid immunoglobulins
US5116964A (en) * 1989-02-23 1992-05-26 Genentech, Inc. Hybrid immunoglobulins
DK0417563T3 (da) 1989-09-12 2000-11-06 Hoffmann La Roche TNF-bindende proteiner
US7253264B1 (en) 1990-06-28 2007-08-07 Sanofi-Arentideutschland GmbH Immunoglobulin fusion proteins, their production and use
EP0464533B1 (de) * 1990-06-28 1998-07-29 Hoechst Aktiengesellschaft Fusionsproteine mit immunglobulinanteilen, ihre Herstellung und Verwendung
FR2696188A1 (fr) * 1992-09-25 1994-04-01 Curie Paris Vi Univ Pierre Mar Molécule CD4 de chat, séquence nucléique codant pour cette molécule et leurs applications.
WO1994011028A1 (en) * 1992-11-16 1994-05-26 Centocor, Inc. Compounds having reduced immunogenicity and a method of reducing the immunogenicity of compounds
US5723125A (en) * 1995-12-28 1998-03-03 Tanox Biosystems, Inc. Hybrid with interferon-alpha and an immunoglobulin Fc linked through a non-immunogenic peptide
US5874268A (en) 1996-09-23 1999-02-23 Duke University Method of introducing exogenous compounds into cells by electroporation and apparatus for same
WO2000043551A1 (en) * 1999-01-26 2000-07-27 Cornell Research Foundation, Inc. Determining viral load in double negative t cells
US8025873B2 (en) * 2002-06-20 2011-09-27 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8029803B2 (en) 2002-06-20 2011-10-04 Paladin Labs, Inc. Chimeric antigens for eliciting an immune response
US8007805B2 (en) * 2003-08-08 2011-08-30 Paladin Labs, Inc. Chimeric antigens for breaking host tolerance to foreign antigens
JP2009511024A (ja) * 2005-10-13 2009-03-19 ヴィレックス メディカル コーポレイション 免疫応答を誘導するためのＣ型肝炎ウイルスポリペプチドおよびＦｃフラグメントを含むキメラ抗原

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0108146B1 (de) * 1982-05-12 1987-01-28 The President And Fellows Of Harvard College Hybridproteinekodierende fusionierte Gene, sie enthaltende Klonierungsvektoren und deren Verwendung
GB8308235D0 (en) * 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
JPS61134325A (ja) * 1984-12-04 1986-06-21 Teijin Ltd ハイブリツド抗体遺伝子の発現方法
EP0280710B1 (de) * 1986-08-21 1996-03-20 The Trustees Of Columbia University In The City Of New York Für das t-zell oberflächenprotein t4 kodierende dna und verwendung von t4-fragmenten bei der behandlung von aids
JPH02501192A (ja) * 1987-09-04 1990-04-26 バイオジェン インコーポレイテッド 可溶性ｔ４蛋白を製造するためのｄｎａ配列、組換ｄｎａ分子および方法
PT88641B (pt) * 1987-10-02 1993-04-30 Genentech Inc Metodo para a preparacao de uma variante de adesao
AU618969B2 (en) * 1987-10-02 1992-01-16 Genentech Inc. Adheson variants
IL87902A0 (en) * 1987-10-08 1989-03-31 Dana Farber Cancer Inst Inc Soluble human cd4 fragments and applications thereof
ZA89430B (en) * 1988-01-22 1989-10-25 Gen Hospital Corp Cloned genes encoding ig-cd4 fusion proteins and the use thereof
DK172110B1 (da) * 1988-04-15 1997-10-27 Gen Hospital Corp Fremgangsmåde til isolation af mutanter af DNA-sekvenser og anvendelsen heraf til identifikation af celleoverfladeproteiner
EP0385909B1 (de) * 1989-03-03 1994-07-13 MicroGeneSys, Inc. Kit oder Zusammensetzung zur Vorbeugung oder Behandlung von HIV-1 Infektionen

Also Published As

Publication number Publication date
EP0414178A2 (de) 1991-02-27
WO1991002743A1 (en) 1991-03-07
FI920658A0 (fi) 1992-02-14
US5420264A (en) 1995-05-30
CA2065010A1 (en) 1991-02-24
IE903043A1 (en) 1991-02-27
EP0414178A3 (en) 1991-11-13
DE69029294T2 (de) 1997-05-22
ES2097121T3 (es) 1997-04-01
PT95072A (pt) 1991-05-22
ATE145938T1 (de) 1996-12-15
GR3022039T3 (en) 1997-03-31
AU6429590A (en) 1991-04-03
KR927003613A (ko) 1992-12-18
DE69029294D1 (de) 1997-01-16
EP0414178B1 (de) 1996-12-04
AU648041B2 (en) 1994-04-14
JPH05500611A (ja) 1993-02-12
ZA906246B (en) 1991-07-31

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