DK0405997T3 - Antibiotisk middel - Google Patents

Antibiotisk middel

Info

Publication number
DK0405997T3
DK0405997T3 DK90307124.9T DK90307124T DK0405997T3 DK 0405997 T3 DK0405997 T3 DK 0405997T3 DK 90307124 T DK90307124 T DK 90307124T DK 0405997 T3 DK0405997 T3 DK 0405997T3
Authority
DK
Denmark
Prior art keywords
antibiotic
cultivation
isolation
production
activity against
Prior art date
Application number
DK90307124.9T
Other languages
Danish (da)
English (en)
Inventor
Robert E Schwartz
Raymond F White
Jerrold M Liesch
Otto D Hensens
Henry Joshua
Dennis M Schmatz
Jan S Tkacz
Louis Kaplan
Margaret S Sosa
Jimmy M Fountoulakis
Robert A Giacobbe
Prakash S Masurekar
Original Assignee
Merck & Co Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US07/492,026 external-priority patent/US5021341A/en
Application filed by Merck & Co Inc filed Critical Merck & Co Inc
Application granted granted Critical
Publication of DK0405997T3 publication Critical patent/DK0405997T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/04—Linear peptides containing only normal peptide links
    • C07K7/06—Linear peptides containing only normal peptide links having 5 to 11 amino acids
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K7/00—Peptides having 5 to 20 amino acids in a fully defined sequence; Derivatives thereof
    • C07K7/50—Cyclic peptides containing at least one abnormal peptide link
    • C07K7/54—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring
    • C07K7/56—Cyclic peptides containing at least one abnormal peptide link with at least one abnormal peptide link in the ring the cyclisation not occurring through 2,4-diamino-butanoic acid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/10—Antimycotics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Genetics & Genomics (AREA)
  • Oncology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Communicable Diseases (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Compounds Of Unknown Constitution (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DK90307124.9T 1989-06-30 1990-06-29 Antibiotisk middel DK0405997T3 (da)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US37441689A 1989-06-30 1989-06-30
US49202590A 1990-03-12 1990-03-12
US49202490A 1990-03-12 1990-03-12
US07/492,026 US5021341A (en) 1990-03-12 1990-03-12 Antibiotic agent produced by the cultivation of Zalerion microorganism in the presence of mannitol

Publications (1)

Publication Number Publication Date
DK0405997T3 true DK0405997T3 (da) 1994-10-31

Family

ID=27503114

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90307124.9T DK0405997T3 (da) 1989-06-30 1990-06-29 Antibiotisk middel

Country Status (16)

Country Link
EP (1) EP0405997B1 (fi)
JP (1) JPH0764873B2 (fi)
KR (1) KR0145693B1 (fi)
AT (1) ATE109160T1 (fi)
AU (1) AU639698B2 (fi)
CA (1) CA2020062C (fi)
CY (1) CY1962A (fi)
DE (1) DE69011006T2 (fi)
DK (1) DK0405997T3 (fi)
ES (1) ES2057413T3 (fi)
FI (1) FI93647C (fi)
HK (1) HK209496A (fi)
IL (1) IL94862A (fi)
NO (1) NO178343C (fi)
NZ (1) NZ234225A (fi)
PT (1) PT94555B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2037957A1 (en) * 1990-03-12 1991-09-13 Merck & Co., Inc. N-acylated cyclohexapeptide compounds
US5310873A (en) * 1990-03-12 1994-05-10 Merck & Co., Inc. Cyclohexapeptide compound
US5330973A (en) 1990-03-19 1994-07-19 Merck & Co., Inc. Lipopeptide derivatives
CA2093429A1 (en) * 1990-10-09 1992-04-10 Shieh-Shung T. Chen Process for biophosphorylating organic compounds
US5219985A (en) * 1990-10-31 1993-06-15 Merck & Co., Inc. Antifungal agent
US5229363A (en) * 1991-02-19 1993-07-20 Merck & Co., Inc. Cyclic hexapeptide compounds
US5369093A (en) * 1991-03-15 1994-11-29 Merck & Co., Inc. Lipopeptide derivatives
US5336756A (en) * 1991-05-01 1994-08-09 Merck & Co., Inc. Process for crystalline cyclic lipopeptides
US6030944A (en) * 1991-10-01 2000-02-29 Merck & Co., Inc. Cyclohexapeptidyl bisamine compounds
US5348940A (en) * 1991-10-01 1994-09-20 Merck & Co., Inc. Cyclohexapeptidyl hydroxypropionitrile compounds
DE69212267T2 (de) * 1991-10-17 1997-01-30 Merck & Co Inc Echinocandin-B-Derivat
US5914313A (en) * 1991-10-17 1999-06-22 Merck & Co., Inc. 1- 4-hydroxy-5-aminoethyloxy-N2 -(10,12-dimethyl-1-oxotetradecyl)ornithine!-5-(3-hydroxyglutamine)-6-(3-hydroxyproline)echinocandin B, other aminoalkyl derivatives and salts thereof
US5378804A (en) * 1993-03-16 1995-01-03 Merck & Co., Inc. Aza cyclohexapeptide compounds
CA2161149A1 (en) * 1993-05-04 1994-11-10 James M. Balkovec Cyclohexapeptidyl aminoalkyl ethers
JP2009514779A (ja) * 2003-07-11 2009-04-09 グラクソ グループ リミテッド 医薬製剤
CN102618604B (zh) * 2011-01-31 2014-09-03 上海天伟生物制药有限公司 一种环脂肽化合物的制备方法

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1183127A (en) * 1979-12-13 1985-02-26 Manuel Debono Process for the preparation of derivatives of cyclic peptide nuclei
CA1182812A (en) * 1979-12-13 1985-02-19 Bernard J. Abbott Process for the preparation of derivatives of cyclic peptide nuclei
EP0057724A1 (en) * 1980-08-15 1982-08-18 Sandoz Ag New metabolites, processes for their production and their use
DE3886001T2 (de) * 1987-10-07 1994-05-26 Merck & Co Inc Fungizides Fermentationsprodukt.

Also Published As

Publication number Publication date
NO178343C (no) 1996-03-06
HK209496A (en) 1996-11-29
FI93647B (fi) 1995-01-31
FI93647C (fi) 1995-05-10
EP0405997A1 (en) 1991-01-02
DE69011006D1 (de) 1994-09-01
CY1962A (en) 1997-07-04
NZ234225A (en) 1993-09-27
JPH03163096A (ja) 1991-07-15
AU5797390A (en) 1991-01-03
FI903280A0 (fi) 1990-06-28
IL94862A (en) 1994-10-07
JPH0764873B2 (ja) 1995-07-12
ES2057413T3 (es) 1994-10-16
IL94862A0 (en) 1991-04-15
NO902921D0 (no) 1990-06-29
ATE109160T1 (de) 1994-08-15
KR0145693B1 (ko) 1998-08-01
CA2020062A1 (en) 1990-12-31
PT94555A (pt) 1991-05-22
EP0405997B1 (en) 1994-07-27
CA2020062C (en) 1997-01-14
KR910001068A (ko) 1991-01-30
PT94555B (pt) 1997-02-28
DE69011006T2 (de) 1995-01-26
NO902921L (no) 1991-01-02
AU639698B2 (en) 1993-08-05
NO178343B (no) 1995-11-27

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