DK0402070T3 - Krystallinsk r-h-GM-CSF og fremgangsmåde til fremstilling heraf - Google Patents

Krystallinsk r-h-GM-CSF og fremgangsmåde til fremstilling heraf

Info

Publication number
DK0402070T3
DK0402070T3 DK90306042.4T DK90306042T DK0402070T3 DK 0402070 T3 DK0402070 T3 DK 0402070T3 DK 90306042 T DK90306042 T DK 90306042T DK 0402070 T3 DK0402070 T3 DK 0402070T3
Authority
DK
Denmark
Prior art keywords
csf
crystalline
preparation
preparing
molecular weight
Prior art date
Application number
DK90306042.4T
Other languages
Danish (da)
English (en)
Inventor
Paul Reichert
Gerald S Hammond
Hung V Le
Tattanahali L Nagabhushan
Paul P Trotta
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Application granted granted Critical
Publication of DK0402070T3 publication Critical patent/DK0402070T3/da

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/52Cytokines; Lymphokines; Interferons
    • C07K14/53Colony-stimulating factor [CSF]
    • C07K14/535Granulocyte CSF; Granulocyte-macrophage CSF
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12PFERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
    • C12P21/00Preparation of peptides or proteins
    • C12P21/02Preparation of peptides or proteins having a known sequence of two or more amino acids, e.g. glutathione
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S930/00Peptide or protein sequence
    • Y10S930/01Peptide or protein sequence
    • Y10S930/14Lymphokine; related peptides
    • Y10S930/145Colony stimulating factor

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Zoology (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Biophysics (AREA)
  • Medicinal Chemistry (AREA)
  • Wood Science & Technology (AREA)
  • Toxicology (AREA)
  • Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Microbiology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Peptides Or Proteins (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Steroid Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Glass Compositions (AREA)
  • Crystals, And After-Treatments Of Crystals (AREA)
  • Silicates, Zeolites, And Molecular Sieves (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Transition And Organic Metals Composition Catalysts For Addition Polymerization (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Mechanical Treatment Of Semiconductor (AREA)
DK90306042.4T 1989-06-06 1990-06-04 Krystallinsk r-h-GM-CSF og fremgangsmåde til fremstilling heraf DK0402070T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/362,187 US5109119A (en) 1989-06-06 1989-06-06 Crystalline r-h-gm-csf and method

Publications (1)

Publication Number Publication Date
DK0402070T3 true DK0402070T3 (da) 1994-09-12

Family

ID=23425041

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90306042.4T DK0402070T3 (da) 1989-06-06 1990-06-04 Krystallinsk r-h-GM-CSF og fremgangsmåde til fremstilling heraf

Country Status (14)

Country Link
US (2) US5109119A (de)
EP (3) EP0561429A1 (de)
JP (1) JP2572160B2 (de)
KR (1) KR960004454B1 (de)
AT (1) ATE110113T1 (de)
AU (1) AU644083B2 (de)
CA (1) CA2058441C (de)
DE (1) DE69011586T2 (de)
DK (1) DK0402070T3 (de)
FI (1) FI915709A0 (de)
HK (1) HK184996A (de)
HU (1) HU209871B (de)
NO (1) NO914771L (de)
WO (1) WO1990015151A1 (de)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU637133B2 (en) * 1989-08-11 1993-05-20 Amrad Operations Pty. Limited Improvements in granulocyte-macrophage colony-stimulating factor receptor and derivatives thereof
EP0955365A3 (de) 1992-06-09 2000-12-20 Chiron Corporation Kristallisierung von M-CSF
US5581476A (en) 1993-01-28 1996-12-03 Amgen Inc. Computer-based methods and articles of manufacture for preparing G-CSF analogs
US6004549A (en) * 1994-12-14 1999-12-21 Schering Corporation Crystalline protein controlled release compositions
US6555660B2 (en) * 2000-01-10 2003-04-29 Maxygen Holdings Ltd. G-CSF conjugates
US6646110B2 (en) * 2000-01-10 2003-11-11 Maxygen Holdings Ltd. G-CSF polypeptides and conjugates
US6831158B2 (en) * 2000-01-10 2004-12-14 Maxygen Holdings Ltd. G-CSF conjugates
PE20020394A1 (es) * 2000-08-18 2002-06-21 Agouron Pharma Compuestos de pirazol y composiciones farmaceuticas que los contienen, que modulan y/o inhiben la actividad de erab/hadh2
ATE468862T1 (de) 2001-07-11 2010-06-15 Maxygen Inc G-csf konjugate
US7765302B2 (en) * 2003-06-30 2010-07-27 Nortel Networks Limited Distributed call server supporting communication sessions in a communication system and method
ATE491475T1 (de) * 2004-07-16 2011-01-15 Nektar Therapeutics Konjugate enthaltend gm-csf und ein polymer
AU2006254543A1 (en) 2005-06-01 2006-12-07 Maxygen Holdings Ltd. PEGylated G-CSF polypeptides and methods of producing same
WO2007102946A2 (en) * 2006-01-23 2007-09-13 Amgen Inc. Crystalline polypeptides
CN105764491A (zh) 2013-12-09 2016-07-13 度瑞公司 药物活性剂复合物、聚合物复合物,以及包括其的组合物和方法

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
AU588819B2 (en) * 1984-10-29 1989-09-28 Immunex Corporation Cloning of human granulocyte-macrophage colony stimulating factor gene
IE59581B1 (en) * 1984-11-20 1994-03-09 Schering Biotech Corp Cdna clones coding for polypeptides exhibiting human granulocyte macrophage and eosinophil cellular growth factor activity
JP2595216B2 (ja) * 1986-12-12 1997-04-02 日清製粉株式会社 α―アミラーゼインヒビターの結晶の製造方法
US4912200A (en) * 1987-05-11 1990-03-27 Schering Corporation Extraction of granulocyte macrophage colony stimulating factor from bacteria
JP2812760B2 (ja) * 1988-05-31 1998-10-22 カイロン コーポレイション 微生物宿主から異種蛋白質を含有する屈折体を回収する方法

Also Published As

Publication number Publication date
NO914771D0 (no) 1991-12-04
ATE110113T1 (de) 1994-09-15
KR920700293A (ko) 1992-02-19
JPH04502014A (ja) 1992-04-09
FI915709A0 (fi) 1991-12-04
KR960004454B1 (ko) 1996-04-06
CA2058441C (en) 1997-12-16
HU904835D0 (en) 1992-02-28
WO1990015151A1 (en) 1990-12-13
HK184996A (en) 1996-10-11
AU644083B2 (en) 1993-12-02
EP0402070A1 (de) 1990-12-12
US5616555A (en) 1997-04-01
NO914771L (no) 1991-12-04
HU209871B (en) 1994-11-28
HUT58822A (en) 1992-03-30
JP2572160B2 (ja) 1997-01-16
EP0561429A1 (de) 1993-09-22
EP0476022A1 (de) 1992-03-25
DE69011586D1 (de) 1994-09-22
US5109119A (en) 1992-04-28
CA2058441A1 (en) 1990-12-07
DE69011586T2 (de) 1995-03-02
AU5834890A (en) 1991-01-07
EP0402070B1 (de) 1994-08-17

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