DK0400916T3 - 4,5,6,11-Tetrahydrobenzo(6,7)-cycloocta(1,2-b)-thiophen-6,11-iminer og 6,11-dihydrobenzo(6,7)- cycloocta(1,2-b)thiophen-6,11 iminer - Google Patents

4,5,6,11-Tetrahydrobenzo(6,7)-cycloocta(1,2-b)-thiophen-6,11-iminer og 6,11-dihydrobenzo(6,7)- cycloocta(1,2-b)thiophen-6,11 iminer

Info

Publication number
DK0400916T3
DK0400916T3 DK90305716.4T DK90305716T DK0400916T3 DK 0400916 T3 DK0400916 T3 DK 0400916T3 DK 90305716 T DK90305716 T DK 90305716T DK 0400916 T3 DK0400916 T3 DK 0400916T3
Authority
DK
Denmark
Prior art keywords
cycloocta
imines
thiophene
compounds
alkyl
Prior art date
Application number
DK90305716.4T
Other languages
English (en)
Inventor
Ralph P Robinson
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Application granted granted Critical
Publication of DK0400916T3 publication Critical patent/DK0400916T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/12—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains three hetero rings
    • C07D495/18—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Neurosurgery (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Neurology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Biomedical Technology (AREA)
  • Public Health (AREA)
  • Vascular Medicine (AREA)
  • Urology & Nephrology (AREA)
  • Hospice & Palliative Care (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Luminescent Compositions (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Macromolecular Compounds Obtained By Forming Nitrogen-Containing Linkages In General (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
DK90305716.4T 1989-06-01 1990-05-25 4,5,6,11-Tetrahydrobenzo(6,7)-cycloocta(1,2-b)-thiophen-6,11-iminer og 6,11-dihydrobenzo(6,7)- cycloocta(1,2-b)thiophen-6,11 iminer DK0400916T3 (da)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
PCT/US1989/002387 WO1990015060A1 (en) 1989-06-01 1989-06-01 4,5,6,11-TETRAHYDROBENZO[6,7]CYCLOOCTA[1,2-b]THIOPHEN-6,11-IMINES AND 6,11-DIHYDROBENZO[6,7]CYCLOOCTA[1,2-b]THIOPHEN-6,11-IMINES

Publications (1)

Publication Number Publication Date
DK0400916T3 true DK0400916T3 (da) 1994-12-05

Family

ID=22215050

Family Applications (1)

Application Number Title Priority Date Filing Date
DK90305716.4T DK0400916T3 (da) 1989-06-01 1990-05-25 4,5,6,11-Tetrahydrobenzo(6,7)-cycloocta(1,2-b)-thiophen-6,11-iminer og 6,11-dihydrobenzo(6,7)- cycloocta(1,2-b)thiophen-6,11 iminer

Country Status (11)

Country Link
EP (1) EP0400916B1 (da)
JP (1) JPH0662630B2 (da)
AT (1) ATE113950T1 (da)
CA (1) CA2017911A1 (da)
DE (1) DE69013983T2 (da)
DK (1) DK0400916T3 (da)
ES (1) ES2063266T3 (da)
FI (1) FI98462C (da)
IE (1) IE64909B1 (da)
PT (1) PT94205B (da)
WO (1) WO1990015060A1 (da)

Families Citing this family (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5196415A (en) * 1989-05-09 1993-03-23 The United States Of America As Represented By The Department Of Health And Human Services 5-aminocarbonyl-5H-dibenzo[a.d]cyclohepten-5,10-imines for treatment of epilepsy and cocaine addiction
US5260309A (en) * 1989-06-01 1993-11-09 Pfizer Inc. 4,5,6,11-tetrahydrobenzo [6,7] cycloocta [1,2-b]thiophen-6,11-imines and 6,11-dihydrobenzo [6,7] cycloocta [1,2-b] thiophen-6,11-imines
GB9002834D0 (en) * 1990-02-08 1990-04-04 Ici America Inc Compounds
US6413410B1 (en) 1996-06-19 2002-07-02 Lifescan, Inc. Electrochemical cell

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3816455A (en) * 1971-04-23 1974-06-11 Mcneilab Inc Certain benzothiepino-indoles and indoline-thiochromans
US4112110A (en) * 1974-02-22 1978-09-05 Ciba-Geigy Corporation Oxygenated azatetracyclic compounds
US4414154A (en) * 1977-09-19 1983-11-08 Merck & Co. Inc. Dibenzo[a,d]cycloocten-5,12-imines
NL7808848A (nl) * 1977-09-19 1979-03-21 Merck & Co Inc Dibenzoa.dcyclo-octeen-5.12-(en 6.12)-iminen.
US4252810A (en) * 1978-11-15 1981-02-24 Merck & Co., Inc. 9,10-Dihydro-4H-benzo[4,5]cyclohepta [1,2-b]thiophen-4,9-imines

Also Published As

Publication number Publication date
PT94205B (pt) 1997-01-31
EP0400916A2 (en) 1990-12-05
ATE113950T1 (de) 1994-11-15
DE69013983D1 (de) 1994-12-15
WO1990015060A1 (en) 1990-12-13
EP0400916B1 (en) 1994-11-09
FI98462C (fi) 1997-06-25
EP0400916A3 (en) 1991-11-27
JPH0320278A (ja) 1991-01-29
IE901951L (en) 1990-12-01
FI915646A0 (fi) 1991-11-29
FI98462B (fi) 1997-03-14
DE69013983T2 (de) 1995-03-16
CA2017911A1 (en) 1990-12-01
JPH0662630B2 (ja) 1994-08-17
IE64909B1 (en) 1995-09-20
ES2063266T3 (es) 1995-01-01
PT94205A (pt) 1991-02-08

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