DK0388019T3 - Avermectin-ketal-derivater, der er egnede som antiparasitiske midler - Google Patents
Avermectin-ketal-derivater, der er egnede som antiparasitiske midlerInfo
- Publication number
- DK0388019T3 DK0388019T3 DK90301638.4T DK90301638T DK0388019T3 DK 0388019 T3 DK0388019 T3 DK 0388019T3 DK 90301638 T DK90301638 T DK 90301638T DK 0388019 T3 DK0388019 T3 DK 0388019T3
- Authority
- DK
- Denmark
- Prior art keywords
- avermectin
- antiparasitic agents
- derivatives useful
- ketal
- ketal derivatives
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D493/00—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system
- C07D493/22—Heterocyclic compounds containing oxygen atoms as the only ring hetero atoms in the condensed system in which the condensed system contains four or more hetero rings
-
- A—HUMAN NECESSITIES
- A01—AGRICULTURE; FORESTRY; ANIMAL HUSBANDRY; HUNTING; TRAPPING; FISHING
- A01N—PRESERVATION OF BODIES OF HUMANS OR ANIMALS OR PLANTS OR PARTS THEREOF; BIOCIDES, e.g. AS DISINFECTANTS, AS PESTICIDES OR AS HERBICIDES; PEST REPELLANTS OR ATTRACTANTS; PLANT GROWTH REGULATORS
- A01N43/00—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds
- A01N43/90—Biocides, pest repellants or attractants, or plant growth regulators containing heterocyclic compounds having two or more relevant hetero rings, condensed among themselves or with a common carbocyclic ring system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P33/00—Antiparasitic agents
- A61P33/10—Anthelmintics
Landscapes
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Dentistry (AREA)
- Veterinary Medicine (AREA)
- Plant Pathology (AREA)
- Wood Science & Technology (AREA)
- Zoology (AREA)
- Environmental Sciences (AREA)
- Pest Control & Pesticides (AREA)
- Agronomy & Crop Science (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Tropical Medicine & Parasitology (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Saccharide Compounds (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US31126889A | 1989-02-16 | 1989-02-16 |
Publications (1)
Publication Number | Publication Date |
---|---|
DK0388019T3 true DK0388019T3 (da) | 1994-05-24 |
Family
ID=23206158
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DK90301638.4T DK0388019T3 (da) | 1989-02-16 | 1990-02-15 | Avermectin-ketal-derivater, der er egnede som antiparasitiske midler |
Country Status (11)
Country | Link |
---|---|
US (1) | US5077308A (de) |
EP (1) | EP0388019B1 (de) |
JP (1) | JPH02270880A (de) |
AT (1) | ATE104983T1 (de) |
AU (1) | AU623744B2 (de) |
CA (1) | CA2010078A1 (de) |
DE (1) | DE69008399T2 (de) |
DK (1) | DK0388019T3 (de) |
ES (1) | ES2063256T3 (de) |
NZ (1) | NZ232422A (de) |
ZA (1) | ZA901148B (de) |
Families Citing this family (65)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
IL119649A (en) * | 1995-11-30 | 2002-03-10 | Akzo Nobel Nv | Preparation of Cyclic Kills of History - 3 keto- (5) 10, (-9) 11 steroidadians |
CN1205921C (zh) * | 1997-12-03 | 2005-06-15 | 麦克公司 | 含有氢化蓖麻油的长效注射制剂 |
US6733767B2 (en) | 1998-03-19 | 2004-05-11 | Merck & Co., Inc. | Liquid polymeric compositions for controlled release of bioactive substances |
US6787342B2 (en) | 2000-02-16 | 2004-09-07 | Merial Limited | Paste formulations |
US20060205681A1 (en) * | 2002-06-21 | 2006-09-14 | Maryam Moaddeb | Homogenous paste formulations |
US7001889B2 (en) * | 2002-06-21 | 2006-02-21 | Merial Limited | Anthelmintic oral homogeneous veterinary pastes |
US20040077703A1 (en) * | 2002-10-02 | 2004-04-22 | Soll Mark D. | Nodulisporic acid derivative spot-on formulations for combating parasites |
US7531186B2 (en) | 2003-12-17 | 2009-05-12 | Merial Limited | Topical formulations comprising 1-N-arylpyrazole derivatives and amitraz |
US8362086B2 (en) | 2005-08-19 | 2013-01-29 | Merial Limited | Long acting injectable formulations |
US20080027011A1 (en) * | 2005-12-20 | 2008-01-31 | Hassan Nached | Homogeneous paste and gel formulations |
KR101437704B1 (ko) | 2006-07-05 | 2014-09-04 | 아벤티스 애그리컬쳐 | 1-아릴-5-알킬 피라졸 유도체 화합물, 이의 제조 방법 및 이의 사용 방법 |
US8901163B2 (en) | 2007-01-03 | 2014-12-02 | Galderma S.A. | Method of treating hyperesthesia, paresthesia, dolor, and pruritus caused by insect stings or noxious weeds or plants using avermectin compound |
ES2825198T3 (es) | 2007-05-15 | 2021-05-14 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de ariloazol-2-il cianoetilamino, procedimiento de fabricación y procedimiento de utilización de los mismos |
MX2010005685A (es) | 2007-11-26 | 2010-09-28 | Merial Ltd | Sistemas de solventes para formulaciones de vaciado determinado para combatir parasitos. |
CA2710171C (en) | 2007-12-21 | 2016-02-02 | Merial Limited | The use of 6-halogeno-[1,2,4]-triazolo-[1,5-a]-pyrimidine compounds for combating pests in and on animals |
US20100022469A1 (en) * | 2008-06-24 | 2010-01-28 | Majid Razzak | Anthelminthic formulations |
AR074024A1 (es) | 2008-11-14 | 2010-12-15 | Merial Ltd | Compuesto de arilazol-2-il-cianoetilamino enantiomericamente enriquecidos, composicion plaguicida y su uso para prevenir la infeccion parasitaria |
US9173728B2 (en) | 2008-11-19 | 2015-11-03 | Merial Inc. | Multi-cavity container having offset indentures for dispensing fluids |
BRPI0922043B1 (pt) | 2008-11-19 | 2019-04-24 | Merial, Inc. | Composições compreendendo um aril pirazol e/ou formamidina, métodos e usos das mesmas |
AR074482A1 (es) | 2008-12-04 | 2011-01-19 | Merial Ltd | Derivados dimericos de avermectina y milbemicina |
AU2010278948B2 (en) | 2009-07-30 | 2015-04-23 | Boehringer Ingelheim Animal Health USA Inc. | Insecticidal 4-Amino-thieno(2,3-d)-pyrimidine compounds and methods of their use |
MX2012006366A (es) | 2009-12-04 | 2012-06-27 | Basf Se | Compuesto de bis-organoazufre plaguicidas. |
US8980896B2 (en) | 2009-12-17 | 2015-03-17 | Merial, Inc. | Compositions comprising macrocyclic lactone compounds and spirodioxepinoindoles |
EP3560923B1 (de) | 2009-12-17 | 2021-05-05 | Boehringer Ingelheim Animal Health USA Inc. | Antiparasitäre dihydroazolverbindungen und zusammensetzungen damit |
UA108641C2 (uk) | 2010-04-02 | 2015-05-25 | Паразитицидна композиція, яка містить чотири активних агенти, та спосіб її застосування | |
US20110281920A1 (en) | 2010-05-12 | 2011-11-17 | Robert Holmes | Injectable parasiticidal formulations of levamisole and macrocyclic lactones |
EP2629772B1 (de) | 2010-10-20 | 2016-05-18 | Galderma S.A. | Ivermectin zur behandlung von hämorrhoiden |
EP2629770B1 (de) | 2010-10-20 | 2016-05-25 | Galderma S.A. | Ivermectin zur behandlung von gehörgangsentzündungen |
HUE031125T2 (en) | 2010-11-16 | 2017-07-28 | Merial Inc | New monensin derivatives for the treatment and prevention of protozoal infections |
AU2011338573B2 (en) | 2010-12-07 | 2016-07-28 | Boehringer Ingelheim Animal Health USA Inc. | Topical combination formulations of macrocyclic lactones with synthetic pyrethroids |
CA2840396C (en) | 2011-06-27 | 2020-07-14 | Merial Limited | Amido-pyridyl ether compounds and compositions and their use against parasites |
US20120329832A1 (en) | 2011-06-27 | 2012-12-27 | Jean Delaveau | Novel Insect-Repellent Coumarin Derivatives, Syntheses, and Methods of Use |
WO2013039948A1 (en) | 2011-09-12 | 2013-03-21 | Merial Limited | Parasiticidal compositions comprising an isoxazoline active agent, methods and uses thereof |
US20130079394A1 (en) | 2011-09-23 | 2013-03-28 | Cnrs (Centre National Recherche Scientifique) | Indirect modeling of new repellent molecules active against insects, acarids, and other arthropods |
AU2012340351B2 (en) | 2011-11-17 | 2017-06-15 | Boehringer Ingelheim Animal Health USA Inc. | Compositions comprising an aryl pyrazole and a substituted imidazole, methods and uses thereof |
US8715711B2 (en) | 2011-12-02 | 2014-05-06 | Merial Limited | Long-acting injectable moxidectin formulations and novel moxidectin crystal forms |
HUE041514T2 (hu) | 2012-02-06 | 2019-05-28 | Merial Inc | Szisztémásan ható hatóanyagokat tartalmazó, parazitaellenes, szájon át adagolt állatgyógyászati készítmények, eljárások és alkalmazásuk |
JO3626B1 (ar) | 2012-02-23 | 2020-08-27 | Merial Inc | تركيبات موضعية تحتوي على فيبرونيل و بيرميثرين و طرق استخدامها |
CA2870956C (en) | 2012-04-20 | 2020-03-31 | Merial Limited | Parasiticidal compositions comprising benzimidazole derivatives, methods and uses thereof |
AP3965A (en) | 2012-11-20 | 2016-12-24 | Merial Ltd | Anthelminitic compounds and compositions and method of using thereof |
LT2950795T (lt) | 2013-01-31 | 2018-06-25 | Merial, Inc. | Leišmaniozės gydymo ir naikinimo būdas naudojant feksinidazolą |
ES2905848T3 (es) | 2013-11-01 | 2022-04-12 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de isoxazolina antiparasitarios y plaguicidas |
ES2765405T3 (es) | 2014-04-17 | 2020-06-09 | Boehringer Ingelheim Animal Health Usa Inc | Utilización de compuestos de malononitrilo para proteger animales de parásitos |
NZ726874A (en) | 2014-05-19 | 2018-03-23 | Merial Inc | Anthelmintic compounds |
PT3157912T (pt) | 2014-06-19 | 2019-06-04 | Boehringer Ingelheim Animal Health Usa Inc | Composições parasiticidas compreendendo derivados de indole, seus métodos e suas utilizações |
WO2016069983A1 (en) | 2014-10-31 | 2016-05-06 | Merial, Inc. | Parasiticidal composition comprising fipronil |
UY36570A (es) | 2015-02-26 | 2016-10-31 | Merial Inc | Formulaciones inyectables de acción prolongada que comprenden un agente activo isoxazolina, métodos y usos de las mismas |
BR112017021073A2 (pt) | 2015-04-08 | 2018-07-03 | Merial Inc | composições injetáveis de liberação prolongada compreendendo um agente ativo de isoxazolina, seus métodos e usos |
TWI749509B (zh) | 2015-05-20 | 2021-12-11 | 美商百靈佳殷格翰動物保健美國有限公司 | 驅蟲酯肽化合物 |
EP3303385A2 (de) | 2015-05-27 | 2018-04-11 | Merial, Inc. | Zusammensetzungen mit antimikrobiellen igy-antikörpern zur behandlung und prävention von störungen und erkrankungen durch die mundgesundheit beeinträchtigende mikroorganismen |
UY37137A (es) | 2016-02-24 | 2017-09-29 | Merial Inc | Compuestos antiparasitarios de isoxazolina, formulaciones inyectables de acción prolongada que los comprenden, métodos y usos de los mismos |
WO2018039508A1 (en) | 2016-08-25 | 2018-03-01 | Merial, Inc. | Method for reducing unwanted effects in parasiticidal treatments |
US10653144B2 (en) | 2016-10-14 | 2020-05-19 | Boehringer Ingelheim Animal Health USA Inc. | Pesticidal and parasiticidal vinyl isoxazoline compounds |
CA3044038A1 (en) | 2016-11-16 | 2018-05-24 | Boehringer Ingelheim Animal Health USA Inc. | Anthelmintic depsipeptide compounds |
US11147273B2 (en) | 2017-06-26 | 2021-10-19 | Boehringer Ingelheim Animal Health USA Inc. | Dual active parasiticidal granule compositions, methods and uses thereof |
AU2018318945A1 (en) | 2017-08-14 | 2020-03-05 | Boehringer Ingelheim Animal Health USA Inc. | Pesticidal and parasiticidal pyrazole-isoxazoline compounds |
EP3749096A1 (de) | 2018-02-08 | 2020-12-16 | Boehringer Ingelheim Animal Health USA Inc. | Parasitizide zusammensetzungen mit eprinomectin und praziquantel, verfahren und verwendungen davon |
AU2019301510B2 (en) | 2018-07-09 | 2024-06-13 | Boehringer Ingelheim Pharma Gmbh & Co. Kg | Anthelminthic heterocyclic compounds |
EP3883648A1 (de) | 2018-11-20 | 2021-09-29 | Boehringer Ingelheim Animal Health USA Inc. | Indazolylcyanoethylaminoverbindung, zusammensetzungen davon, verfahren zur herstellung und verfahren zur verwendung davon |
AU2020208145B2 (en) | 2019-01-16 | 2023-02-02 | Boehringer Ingelheim Vetmedica Gmbh | Topical compositions comprising a neonicotinoid and a macrocyclic lactone, methods and uses thereof |
CN113507922A (zh) | 2019-03-01 | 2021-10-15 | 勃林格殷格翰动物保健美国公司 | 可注射的氯舒隆组合物、其方法和用途 |
CR20210477A (es) | 2019-03-19 | 2022-01-06 | Boehringer Ingelheim Animal Health Usa Inc | Compuestos de aza-benzotiofeno y aza-benzofurano como antihelmínticos |
MX2022000843A (es) | 2019-07-22 | 2022-02-10 | Intervet Int Bv | Forma de dosificacion blanda masticable de uso veterinario. |
BR112022024156A2 (pt) | 2020-05-29 | 2023-02-14 | Boehringer Ingelheim Animal Health Usa Inc | Compostos heterocílicos antelmínticos |
CN116897044A (zh) | 2020-12-21 | 2023-10-17 | 勃林格殷格翰动物保健有限公司 | 包含异噁唑啉化合物的杀寄生虫环 |
Family Cites Families (12)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3950360A (en) * | 1972-06-08 | 1976-04-13 | Sankyo Company Limited | Antibiotic substances |
SE434277B (sv) * | 1976-04-19 | 1984-07-16 | Merck & Co Inc | Sett att framstella nya antihelmintiskt verkande foreningar genom odling av streptomyces avermitilis |
USRE32006E (en) * | 1977-12-19 | 1985-10-15 | Merck & Co., Inc. | 13-Halo and 13-deoxy C-076 compounds |
USRE32032E (en) * | 1978-02-10 | 1985-11-19 | Foam Cutting Engineers, Inc. | Method of densifying open-celled polyurethane material |
US4200581A (en) * | 1978-08-04 | 1980-04-29 | Merck & Co., Inc. | Alkyl derivatives of C-076 compounds |
JPS59108785A (ja) * | 1982-11-25 | 1984-06-23 | Sankyo Co Ltd | ミルベマイシン類の5−オキシム誘導体 |
DE3519834C2 (de) * | 1984-06-05 | 1993-12-16 | American Cyanamid Co | Neue antibiotische Wirkstoffe, Verfahren zu ihrer Gewinnung und ihre Anwendung zur Bekämpfung von Infektionen bei Tieren und Pflanzen |
BE903232A (fr) * | 1984-09-14 | 1986-03-13 | Glaxo Group Ltd | Composes antibiotiques et leur procede de preparation |
HUT39739A (en) * | 1984-12-04 | 1986-10-29 | Ciba Geigy Ag | Process for production of derivatives of 13,3-milbemycin and medical preparatives containing thereof |
JP2587241B2 (ja) * | 1986-07-24 | 1997-03-05 | ビ−チヤム・グル−プ・ピ−エルシ− | 新規化合物、その製法及びそれを含む医薬組成物 |
ES2053797T3 (es) * | 1987-02-04 | 1994-08-01 | Ciba Geigy Ag | Procedimiento microbiano para la obtencion de derivados de milbemicina. |
US4871719A (en) * | 1987-03-24 | 1989-10-03 | Ciba-Geigy Corporation | Composition for controlling parasites in productive livestock |
-
1990
- 1990-02-08 NZ NZ232422A patent/NZ232422A/xx unknown
- 1990-02-14 CA CA002010078A patent/CA2010078A1/en not_active Abandoned
- 1990-02-15 DE DE69008399T patent/DE69008399T2/de not_active Expired - Fee Related
- 1990-02-15 AU AU49830/90A patent/AU623744B2/en not_active Ceased
- 1990-02-15 EP EP90301638A patent/EP0388019B1/de not_active Expired - Lifetime
- 1990-02-15 AT AT9090301638T patent/ATE104983T1/de active
- 1990-02-15 ZA ZA901148A patent/ZA901148B/xx unknown
- 1990-02-15 DK DK90301638.4T patent/DK0388019T3/da active
- 1990-02-15 ES ES90301638T patent/ES2063256T3/es not_active Expired - Lifetime
- 1990-02-16 JP JP2034038A patent/JPH02270880A/ja active Pending
- 1990-07-23 US US07/556,044 patent/US5077308A/en not_active Expired - Lifetime
Also Published As
Publication number | Publication date |
---|---|
AU4983090A (en) | 1991-08-29 |
ES2063256T3 (es) | 1995-01-01 |
CA2010078A1 (en) | 1990-08-16 |
AU623744B2 (en) | 1992-05-21 |
NZ232422A (en) | 1992-11-25 |
DE69008399D1 (de) | 1994-06-01 |
EP0388019B1 (de) | 1994-04-27 |
ATE104983T1 (de) | 1994-05-15 |
US5077308A (en) | 1991-12-31 |
ZA901148B (en) | 1990-10-31 |
EP0388019A1 (de) | 1990-09-19 |
JPH02270880A (ja) | 1990-11-05 |
DE69008399T2 (de) | 1994-10-27 |
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