DK0382113T3 - Fremgangsmåde til enzymatisk adskillelse af 2-amino-4-methylphosphinosmørsyrederivater - Google Patents
Fremgangsmåde til enzymatisk adskillelse af 2-amino-4-methylphosphinosmørsyrederivaterInfo
- Publication number
- DK0382113T3 DK0382113T3 DK90102068.5T DK90102068T DK0382113T3 DK 0382113 T3 DK0382113 T3 DK 0382113T3 DK 90102068 T DK90102068 T DK 90102068T DK 0382113 T3 DK0382113 T3 DK 0382113T3
- Authority
- DK
- Denmark
- Prior art keywords
- ptc
- amino
- acid derivatives
- aqueous
- derivatives
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- NIBLDNQQTIFBAI-UHFFFAOYSA-N 2-amino-4-methylphosphanylbutanoic acid Chemical class CPCCC(N)C(O)=O NIBLDNQQTIFBAI-UHFFFAOYSA-N 0.000 title 1
- 230000002255 enzymatic effect Effects 0.000 title 1
- 238000000926 separation method Methods 0.000 title 1
- 125000003178 carboxy group Chemical group [H]OC(*)=O 0.000 abstract 2
- NIBLDNQQTIFBAI-BYPYZUCNSA-N CPCC[C@H](N)C(O)=O Chemical compound CPCC[C@H](N)C(O)=O NIBLDNQQTIFBAI-BYPYZUCNSA-N 0.000 abstract 1
- 102000004190 Enzymes Human genes 0.000 abstract 1
- 108090000790 Enzymes Proteins 0.000 abstract 1
- IAJOBQBIJHVGMQ-BYPYZUCNSA-N glufosinate-P Chemical compound CP(O)(=O)CC[C@H](N)C(O)=O IAJOBQBIJHVGMQ-BYPYZUCNSA-N 0.000 abstract 1
- 230000002363 herbicidal effect Effects 0.000 abstract 1
- 230000003301 hydrolyzing effect Effects 0.000 abstract 1
- 239000000203 mixture Substances 0.000 abstract 1
- ACVYVLVWPXVTIT-UHFFFAOYSA-N phosphinic acid Chemical group O[PH2]=O ACVYVLVWPXVTIT-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P41/00—Processes using enzymes or microorganisms to separate optical isomers from a racemic mixture
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/301—Acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/28—Phosphorus compounds with one or more P—C bonds
- C07F9/30—Phosphinic acids [R2P(=O)(OH)]; Thiophosphinic acids ; [R2P(=X1)(X2H) (X1, X2 are each independently O, S or Se)]
- C07F9/32—Esters thereof
- C07F9/3205—Esters thereof the acid moiety containing a substituent or a structure which is considered as characteristic
- C07F9/3211—Esters of acyclic saturated acids which can have further substituents on alkyl
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/02—Amides, e.g. chloramphenicol or polyamides; Imides or polyimides; Urethanes, i.e. compounds comprising N-C=O structural element or polyurethanes
-
- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12P—FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIRED CHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERS FROM A RACEMIC MIXTURE
- C12P13/00—Preparation of nitrogen-containing organic compounds
- C12P13/04—Alpha- or beta- amino acids
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/874—Pseudomonas
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
- Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y10S435/00—Chemistry: molecular biology and microbiology
- Y10S435/8215—Microorganisms
- Y10S435/822—Microorganisms using bacteria or actinomycetales
- Y10S435/874—Pseudomonas
- Y10S435/876—Pseudomonas fluorescens
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Wood Science & Technology (AREA)
- Engineering & Computer Science (AREA)
- Zoology (AREA)
- Biochemistry (AREA)
- General Health & Medical Sciences (AREA)
- Health & Medical Sciences (AREA)
- General Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Microbiology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Biotechnology (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Genetics & Genomics (AREA)
- Molecular Biology (AREA)
- Analytical Chemistry (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Enzymes And Modification Thereof (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| DE3903446A DE3903446A1 (de) | 1989-02-06 | 1989-02-06 | Verfahren zur enzymatischen trennung von 2-amino-4-methylphosphinobuttersaeurederivaten |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0382113T3 true DK0382113T3 (da) | 1995-02-13 |
Family
ID=6373501
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90102068.5T DK0382113T3 (da) | 1989-02-06 | 1990-02-02 | Fremgangsmåde til enzymatisk adskillelse af 2-amino-4-methylphosphinosmørsyrederivater |
Country Status (10)
| Country | Link |
|---|---|
| US (3) | US5756800A (da) |
| EP (1) | EP0382113B1 (da) |
| JP (1) | JP2846694B2 (da) |
| KR (1) | KR100237520B1 (da) |
| AT (1) | ATE111959T1 (da) |
| AU (1) | AU627546B2 (da) |
| CA (1) | CA2009295C (da) |
| DE (2) | DE3903446A1 (da) |
| DK (1) | DK0382113T3 (da) |
| ES (1) | ES2064500T3 (da) |
Families Citing this family (12)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE3724722A1 (de) * | 1987-07-25 | 1989-02-16 | Hoechst Ag | Verbessertes verfahren zur enzymatischen herstellung von l-2-amino-4-methylphosphinobuttersaeure |
| DE3903446A1 (de) * | 1989-02-06 | 1990-10-18 | Hoechst Ag | Verfahren zur enzymatischen trennung von 2-amino-4-methylphosphinobuttersaeurederivaten |
| DE59010545D1 (de) * | 1989-02-06 | 1996-11-28 | Hoechst Schering Agrevo Gmbh | Phosphinesterhaltige N-Acyl-2-aminosäureamide, Verfahren zu ihrer Herstellung und N-Acyl-2-aminosäurenitrile als Vorprodukte |
| DE4407197A1 (de) * | 1994-03-04 | 1995-09-07 | Hoechst Schering Agrevo Gmbh | Verfahren zur Herstellung von /L/-Homoalanin-4-yl-(methyl)phosphinsäure und deren Salze durch Racematspaltung |
| DE4422045A1 (de) | 1994-06-26 | 1996-01-04 | Hoechst Schering Agrevo Gmbh | Verfahren zur enzymatischen Spaltung von 2-Amino-4-methylphosphinobutansäureamid-Derivaten |
| DE19955283A1 (de) * | 1999-11-17 | 2001-05-23 | Aventis Res & Tech Gmbh & Co | Verfahren zur enantioselektiven Gewinnung von Aminosäuren und Aminosäurederivaten unter Verwendung von Racemisierungskatalysatoren |
| TWI397380B (zh) * | 2006-09-20 | 2013-06-01 | Meiji Seika Kaisha | 含磷之α胺基酸之製造方法及其製造中間體 |
| US8981142B2 (en) | 2010-04-14 | 2015-03-17 | Strategic Enzyme Applications, Inc. | Process of producing phosphinothricin employing nitrilases |
| CN108191909B (zh) * | 2018-01-12 | 2020-05-01 | Ati化学国际公司 | 一种氢化法制备草铵膦酸的工艺 |
| CN110343676B (zh) | 2018-04-03 | 2020-06-23 | 上海弈柯莱生物医药科技有限公司 | 一种l-谷氨酸脱氢酶突变体及其应用 |
| CN111979208B (zh) | 2019-05-23 | 2023-01-10 | 弈柯莱生物科技(上海)股份有限公司 | 一种l-谷氨酸脱氢酶突变体及其应用 |
| CN112940031B (zh) * | 2021-02-01 | 2022-08-02 | 河北威远生物化工有限公司 | 一种n-萘乙酰草铵膦及其合成方法及以其合成l-草铵膦的合成方法 |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| CA947214A (en) * | 1971-04-02 | 1974-05-14 | Antoine D'iorio | Resolution of racemates of ring-substituted phenylalanines |
| WO1979001114A1 (en) * | 1978-05-25 | 1979-12-13 | Meiji Seika Kaisha | Dialkyl 4-methylphosphinobutyrates and process for producing same |
| JPS557237A (en) * | 1978-07-03 | 1980-01-19 | Meiji Seika Kaisha Ltd | Novel phosphorus-containing compound, its preparation, herbicide, agricultural and horticultural fungicide comprising it |
| JPS5547630A (en) * | 1978-10-02 | 1980-04-04 | Meiji Seika Kaisha Ltd | Optical resolution of phosphorus-containing amino acid |
| DE2927534A1 (de) * | 1979-07-07 | 1981-01-08 | Bayer Ag | Optisch reine heterocyclische aminosaeuren, verfahren zu ihrer herstellung und ihre verwendung |
| DE3048612C2 (de) * | 1980-12-23 | 1982-12-02 | Hoechst Ag, 6000 Frankfurt | "Verfahren zur enzymatischen Trennung von L-2-Ami no-4-methylphosphinobuttersäure" |
| JPS60248191A (ja) * | 1984-05-21 | 1985-12-07 | Satoshi Omura | フオスフイノスリシンの製造方法 |
| DE3435156A1 (de) * | 1984-09-25 | 1986-04-03 | Boehringer Mannheim Gmbh, 6800 Mannheim | Verfahren zur herstellung der stereoisomeren von 1-amino-alkylphosphonsaeuren oder 1-aminoalkylphosphinsaeuren |
| DE3609818A1 (de) * | 1986-03-22 | 1987-09-24 | Hoechst Ag | Verfahren zur herstellung von l-phosphinothricin(derivaten) sowie ihrer alkylester |
| JP2615777B2 (ja) * | 1987-05-26 | 1997-06-04 | 日産化学工業株式会社 | ホスフィニルアミノ酸誘導体の製造方法 |
| DE3724722A1 (de) * | 1987-07-25 | 1989-02-16 | Hoechst Ag | Verbessertes verfahren zur enzymatischen herstellung von l-2-amino-4-methylphosphinobuttersaeure |
| DE3727243A1 (de) * | 1987-08-15 | 1989-02-23 | Hoechst Ag | Verfahren zur enzymatischen herstellung optisch aktiver phosphorhaltiger funktioneller essigsaeurederivate |
| DE3903446A1 (de) * | 1989-02-06 | 1990-10-18 | Hoechst Ag | Verfahren zur enzymatischen trennung von 2-amino-4-methylphosphinobuttersaeurederivaten |
| DE59010545D1 (de) * | 1989-02-06 | 1996-11-28 | Hoechst Schering Agrevo Gmbh | Phosphinesterhaltige N-Acyl-2-aminosäureamide, Verfahren zu ihrer Herstellung und N-Acyl-2-aminosäurenitrile als Vorprodukte |
-
1989
- 1989-02-06 DE DE3903446A patent/DE3903446A1/de not_active Withdrawn
-
1990
- 1990-02-02 ES ES90102068T patent/ES2064500T3/es not_active Expired - Lifetime
- 1990-02-02 DK DK90102068.5T patent/DK0382113T3/da active
- 1990-02-02 DE DE59007179T patent/DE59007179D1/de not_active Expired - Lifetime
- 1990-02-02 EP EP90102068A patent/EP0382113B1/de not_active Expired - Lifetime
- 1990-02-02 AT AT90102068T patent/ATE111959T1/de not_active IP Right Cessation
- 1990-02-05 CA CA002009295A patent/CA2009295C/en not_active Expired - Lifetime
- 1990-02-05 JP JP2024571A patent/JP2846694B2/ja not_active Expired - Lifetime
- 1990-02-05 KR KR1019900001357A patent/KR100237520B1/ko not_active IP Right Cessation
- 1990-02-06 AU AU49117/90A patent/AU627546B2/en not_active Expired
-
1995
- 1995-05-25 US US08/450,380 patent/US5756800A/en not_active Expired - Lifetime
-
1996
- 1996-01-23 US US08/589,999 patent/US5756346A/en not_active Expired - Lifetime
-
1998
- 1998-01-05 US US09/002,620 patent/US5879930A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| AU627546B2 (en) | 1992-08-27 |
| JP2846694B2 (ja) | 1999-01-13 |
| KR900013080A (ko) | 1990-09-03 |
| US5879930A (en) | 1999-03-09 |
| EP0382113A1 (de) | 1990-08-16 |
| AU4911790A (en) | 1990-08-09 |
| JPH02245197A (ja) | 1990-09-28 |
| ES2064500T3 (es) | 1995-02-01 |
| DE59007179D1 (de) | 1994-10-27 |
| CA2009295A1 (en) | 1990-08-06 |
| KR100237520B1 (ko) | 2000-01-15 |
| US5756800A (en) | 1998-05-26 |
| US5756346A (en) | 1998-05-26 |
| ATE111959T1 (de) | 1994-10-15 |
| DE3903446A1 (de) | 1990-10-18 |
| EP0382113B1 (de) | 1994-09-21 |
| CA2009295C (en) | 2000-08-01 |
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