DK0379145T3 - Substituerede quinolincarboxylsyrer - Google Patents
Substituerede quinolincarboxylsyrerInfo
- Publication number
- DK0379145T3 DK0379145T3 DK90100839.1T DK90100839T DK0379145T3 DK 0379145 T3 DK0379145 T3 DK 0379145T3 DK 90100839 T DK90100839 T DK 90100839T DK 0379145 T3 DK0379145 T3 DK 0379145T3
- Authority
- DK
- Denmark
- Prior art keywords
- carboxylic acids
- quinoline carboxylic
- substituted quinoline
- disclosed
- substituted
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/38—Nitrogen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/48—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen
- C07D215/50—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4
- C07D215/52—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen attached in position 4 with aryl radicals attached in position 2
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/47—Quinolines; Isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P19/00—Drugs for skeletal disorders
- A61P19/02—Drugs for skeletal disorders for joint disorders, e.g. arthritis, arthrosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
- A61P37/06—Immunosuppressants, e.g. drugs for graft rejection
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Veterinary Medicine (AREA)
- Public Health (AREA)
- Immunology (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Medicinal Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- General Chemical & Material Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Rheumatology (AREA)
- Pain & Pain Management (AREA)
- Transplantation (AREA)
- Orthopedic Medicine & Surgery (AREA)
- Physical Education & Sports Medicine (AREA)
- Epidemiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Quinoline Compounds (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US07/298,585 US4968702A (en) | 1989-01-17 | 1989-01-17 | Substituted quinolinecarboxylic acids |
Publications (1)
| Publication Number | Publication Date |
|---|---|
| DK0379145T3 true DK0379145T3 (da) | 1997-05-26 |
Family
ID=23151154
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK90100839.1T DK0379145T3 (da) | 1989-01-17 | 1990-01-16 | Substituerede quinolincarboxylsyrer |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4968702A (ko) |
| EP (1) | EP0379145B1 (ko) |
| JP (1) | JP3004025B2 (ko) |
| KR (1) | KR0140076B1 (ko) |
| AT (1) | ATE152711T1 (ko) |
| AU (1) | AU624471B2 (ko) |
| CA (1) | CA2007740C (ko) |
| DE (1) | DE69030632T2 (ko) |
| DK (1) | DK0379145T3 (ko) |
| ES (1) | ES2100851T3 (ko) |
| GR (1) | GR3023585T3 (ko) |
| HK (1) | HK1008019A1 (ko) |
| IE (1) | IE900169L (ko) |
| IL (1) | IL92898A (ko) |
| NZ (1) | NZ232111A (ko) |
| PH (1) | PH26961A (ko) |
| ZA (1) | ZA90299B (ko) |
Families Citing this family (19)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5310732A (en) * | 1986-02-03 | 1994-05-10 | The Scripps Research Institute | 2-halo-2'-deoxyadenosines in the treatment of rheumatoid arthritis |
| US5409886A (en) * | 1993-02-18 | 1995-04-25 | Mitsui Toatsu Chemicals, Incorporated | 3-pyrroline-2-one derivatives and herbicidal compositions containing same |
| US5393891A (en) * | 1993-06-08 | 1995-02-28 | The Du Pont Merck Pharmaceutical Company | Immunoassay reagents and methods for detecting brequinar and analogs |
| US5428040A (en) * | 1993-08-31 | 1995-06-27 | The Du Pont Merck Pharmaceutical Company | Carbocyclic fused-ring quinolinecarboxylic acids useful as immunosuppressive agents |
| US5453431A (en) * | 1993-10-29 | 1995-09-26 | Gilman; Andrew L. | Use of hydroxychloroquine for treatment of graft-versus-host disease |
| US5578609A (en) * | 1994-03-25 | 1996-11-26 | The Dupont Merck Pharmaceutical Company | 2-carbocyclic and 2-heterocyclic quinoline-4-carboxylic acids and salts thereof useful as immunosuppressive agents |
| AU757059B2 (en) | 1997-06-19 | 2003-01-30 | Sepracor, Inc. | Quinoline-indole antimicrobial agents, uses and compositions related thereto |
| US6103905A (en) * | 1997-06-19 | 2000-08-15 | Sepracor, Inc. | Quinoline-indole antimicrobial agents, uses and compositions related thereto |
| US6207679B1 (en) | 1997-06-19 | 2001-03-27 | Sepracor, Inc. | Antimicrobial agents uses and compositions related thereto |
| US6376670B1 (en) | 1997-06-19 | 2002-04-23 | Sepracor Inc. | Quinoline-indole antimicrobial agents, uses and compositions related thereto |
| WO1999038846A1 (en) * | 1998-01-30 | 1999-08-05 | Procept, Inc. | Immunosuppressive agents |
| AR029489A1 (es) | 2000-03-10 | 2003-07-02 | Euro Celtique Sa | Piridinas, pirimidinas, pirazinas, triazinas sustituidas por arilo, composiciones farmaceuticas y el uso de las mismas para la manufactura de un medicamento |
| AR037233A1 (es) | 2001-09-07 | 2004-11-03 | Euro Celtique Sa | Piridinas aril sustituidas, composiciones farmaceuticas y el uso de dichos compuestos para la elaboracion de un medicamento |
| AR036873A1 (es) * | 2001-09-07 | 2004-10-13 | Euro Celtique Sa | Piridinas aril sustituidas a, composiciones farmaceuticas y el uso de las mismas para la preparacion de un medicamento |
| MXPA05001642A (es) * | 2002-08-13 | 2005-04-25 | Warner Lambert Co | Derivados de naftaleno como inhibidores de metaloproteinasas de matriz. |
| US7138412B2 (en) * | 2003-03-11 | 2006-11-21 | Bristol-Myers Squibb Company | Tetrahydroquinoline derivatives useful as serine protease inhibitors |
| WO2006115509A2 (en) | 2004-06-24 | 2006-11-02 | Novartis Vaccines And Diagnostics Inc. | Small molecule immunopotentiators and assays for their detection |
| CA2898615A1 (en) * | 2013-01-28 | 2014-07-31 | Viamet Pharmaceuticals, Inc. | Metalloenzyme inhibitor compounds |
| KR20160079123A (ko) | 2013-11-22 | 2016-07-05 | 젠자임 코포레이션 | 신경변성 질병을 치료하기 위한 신규한 방법 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| DE287804C (ko) * | ||||
| US2888346A (en) * | 1955-08-22 | 1959-05-26 | Gen Aniline & Film Corp | Ultra-violet absorbing compounds |
| FR2166297A1 (en) * | 1972-01-07 | 1973-08-17 | Rosenberg Eli | 2-(4-isopropylphenyl)quinoline-4-carboxylic acid - as a non-toxic, analgesic agent |
| US4680299A (en) * | 1984-04-30 | 1987-07-14 | E.I. Du Pont De Nemours And Company | 2-phenyl-4-quinolinecarboxylic acids and pharmaceutical compositions thereof |
| EP0133244B1 (en) * | 1983-07-22 | 1990-12-05 | E.I. Du Pont De Nemours And Company | Phenylquinolinecarboxylic acids and derivatives as antitumor agents |
| EP0318093A3 (en) * | 1987-11-25 | 1990-12-05 | Merck Frosst Canada Inc. | Diarylquinoline diacids and their use as medicaments |
-
1989
- 1989-01-17 US US07/298,585 patent/US4968702A/en not_active Expired - Lifetime
- 1989-12-27 IL IL9289889A patent/IL92898A/en unknown
-
1990
- 1990-01-08 PH PH39858A patent/PH26961A/en unknown
- 1990-01-15 CA CA002007740A patent/CA2007740C/en not_active Expired - Lifetime
- 1990-01-15 NZ NZ232111A patent/NZ232111A/en unknown
- 1990-01-16 AU AU48502/90A patent/AU624471B2/en not_active Ceased
- 1990-01-16 ES ES90100839T patent/ES2100851T3/es not_active Expired - Lifetime
- 1990-01-16 KR KR1019900000643A patent/KR0140076B1/ko not_active IP Right Cessation
- 1990-01-16 DE DE69030632T patent/DE69030632T2/de not_active Expired - Fee Related
- 1990-01-16 EP EP90100839A patent/EP0379145B1/en not_active Expired - Lifetime
- 1990-01-16 JP JP2004637A patent/JP3004025B2/ja not_active Expired - Fee Related
- 1990-01-16 ZA ZA90299A patent/ZA90299B/xx unknown
- 1990-01-16 DK DK90100839.1T patent/DK0379145T3/da active
- 1990-01-16 AT AT90100839T patent/ATE152711T1/de not_active IP Right Cessation
- 1990-01-16 IE IE900169A patent/IE900169L/xx not_active IP Right Cessation
-
1997
- 1997-05-30 GR GR950401502T patent/GR3023585T3/el unknown
-
1998
- 1998-06-27 HK HK98107244A patent/HK1008019A1/xx not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| IL92898A0 (en) | 1990-09-17 |
| PH26961A (en) | 1992-12-28 |
| CA2007740A1 (en) | 1990-07-17 |
| KR900011733A (ko) | 1990-08-02 |
| JP3004025B2 (ja) | 2000-01-31 |
| DE69030632D1 (de) | 1997-06-12 |
| GR3023585T3 (en) | 1997-08-29 |
| HK1008019A1 (en) | 1999-04-30 |
| DE69030632T2 (de) | 1997-10-02 |
| AU4850290A (en) | 1990-07-26 |
| US4968702A (en) | 1990-11-06 |
| KR0140076B1 (ko) | 1998-06-01 |
| AU624471B2 (en) | 1992-06-11 |
| ATE152711T1 (de) | 1997-05-15 |
| EP0379145A3 (en) | 1991-07-17 |
| EP0379145B1 (en) | 1997-05-07 |
| CA2007740C (en) | 1999-12-07 |
| JPH02229166A (ja) | 1990-09-11 |
| ES2100851T3 (es) | 1997-07-01 |
| IE900169L (en) | 1990-07-17 |
| IL92898A (en) | 1994-11-28 |
| NZ232111A (en) | 1992-07-28 |
| ZA90299B (en) | 1990-10-31 |
| EP0379145A2 (en) | 1990-07-25 |
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