DE69934694D1 - Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird - Google Patents

Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird

Info

Publication number
DE69934694D1
DE69934694D1 DE69934694T DE69934694T DE69934694D1 DE 69934694 D1 DE69934694 D1 DE 69934694D1 DE 69934694 T DE69934694 T DE 69934694T DE 69934694 T DE69934694 T DE 69934694T DE 69934694 D1 DE69934694 D1 DE 69934694D1
Authority
DE
Germany
Prior art keywords
bpc
cancer cells
expressed
bladder cancer
prostate
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69934694T
Other languages
English (en)
Other versions
DE69934694T2 (de
Inventor
E Afar
S Hubert
Kahan Leong
B Raitano
C Saffran
Aya Jakobovits
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Agensys Inc
Original Assignee
Agensys Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Agensys Inc filed Critical Agensys Inc
Application granted granted Critical
Publication of DE69934694D1 publication Critical patent/DE69934694D1/de
Publication of DE69934694T2 publication Critical patent/DE69934694T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/46—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates
    • C07K14/47—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans from vertebrates from mammals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/08—Drugs for disorders of the urinary system of the prostate
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/10—Drugs for disorders of the urinary system of the bladder
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K48/00—Medicinal preparations containing genetic material which is inserted into cells of the living body to treat genetic diseases; Gene therapy
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2317/00—Immunoglobulins specific features
    • C07K2317/20—Immunoglobulins specific features characterized by taxonomic origin
    • C07K2317/24—Immunoglobulins specific features characterized by taxonomic origin containing regions, domains or residues from different species, e.g. chimeric, humanized or veneered
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
    • C07K2319/01—Fusion polypeptide containing a localisation/targetting motif
    • C07K2319/02—Fusion polypeptide containing a localisation/targetting motif containing a signal sequence
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/026—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a baculovirus
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2799/00—Uses of viruses
    • C12N2799/02—Uses of viruses as vector
    • C12N2799/021—Uses of viruses as vector for the expression of a heterologous nucleic acid
    • C12N2799/027—Uses of viruses as vector for the expression of a heterologous nucleic acid where the vector is derived from a retrovirus

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Urology & Nephrology (AREA)
  • Peptides Or Proteins (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69934694T 1998-08-10 1999-08-10 Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird Expired - Lifetime DE69934694T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US9598298P 1998-08-10 1998-08-10
US95982P 1998-08-10
PCT/US1999/018250 WO2000009691A2 (en) 1998-08-10 1999-08-10 Bpc-1: a secreted brain specific protein expressed and secreted by prostate and bladder cancer cells

Publications (2)

Publication Number Publication Date
DE69934694D1 true DE69934694D1 (de) 2007-02-15
DE69934694T2 DE69934694T2 (de) 2007-10-04

Family

ID=22254489

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69934694T Expired - Lifetime DE69934694T2 (de) 1998-08-10 1999-08-10 Bpc-1: ein ausgeschiedenes gehirnspezifisches protein das von prostata- und blasen-krebszellen exprimiert und ausgeschieden wird

Country Status (9)

Country Link
US (4) US6277972B1 (de)
EP (1) EP1104462B1 (de)
JP (2) JP4282906B2 (de)
AT (1) ATE350474T1 (de)
AU (1) AU756452B2 (de)
CA (1) CA2338982C (de)
DE (1) DE69934694T2 (de)
IL (2) IL141061A0 (de)
WO (1) WO2000009691A2 (de)

Families Citing this family (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US7635687B2 (en) * 1997-06-04 2009-12-22 Oxford Biomedica (Uk) Limited Vector system
WO1998055607A2 (en) * 1997-06-04 1998-12-10 Oxford Biomedica (Uk) Limited Tumor targeted vector
US7276488B2 (en) * 1997-06-04 2007-10-02 Oxford Biomedica (Uk) Limited Vector system
US8096872B2 (en) * 1998-06-22 2012-01-17 Igt Method and apparatus for providing electronic credits at a gaming device without first requiring payment therefor
JP4282906B2 (ja) * 1998-08-10 2009-06-24 アジェンシス，インコーポレイテッド Ｂｐｃ−１：前立腺および膀胱の癌細胞によって発現および分泌がなされる分泌型の脳特異的蛋白質
WO2000071711A2 (en) * 1999-05-20 2000-11-30 Fahri Saatcioglu Differentially expressed genes in prostate cancer
US7611892B2 (en) * 2000-03-24 2009-11-03 President And Fellows Of Harvard College Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
US7189565B2 (en) * 2001-03-23 2007-03-13 Fahri Saatcioglu Prostate-specific or testis-specific nucleic acid molecules, polypeptides, and diagnostic and therapeutic methods
EP1301533A1 (de) * 2000-07-07 2003-04-16 BOEHRINGER INGELHEIM INTERNATIONAL GmbH Tumorassoziiertes antigen (b345), gekennzeichnet durch eine aminosäuresequenz wie in seq. id. no. 4
US7390263B1 (en) * 2000-10-19 2008-06-24 Igt Method of implementing cashless play of gaming devices interconnected by a computer network
GB0126378D0 (en) * 2001-11-02 2002-01-02 Oxford Biomedica Ltd Antigen
AU2003208871A1 (en) * 2002-02-18 2003-09-04 Lynkeus Bio Tech Gmbh Novel retina specific human proteins wdr17, net01, protein kinase a203, protein kinase mak a194, protein a105, protein a106 and c12orf3variants
US20040018580A1 (en) * 2002-05-10 2004-01-29 Chai Karl X. Synthetic substrates for prostasin
WO2004067716A2 (en) * 2003-01-24 2004-08-12 Agensys, Inc. Nucleic acids and corresponding proteins entitled 254p1d6b useful in treatment and detection of cancer
CA2515208A1 (en) * 2003-02-07 2004-08-26 The Regents Of The University Of California Nell peptide expression systems and bone formation activity of nell peptide
WO2005027845A2 (en) * 2003-09-18 2005-03-31 Alexion Pharmaceuticals, Inc. Method of identifying cell surface molecules involved in cancer metastasis
KR20080090406A (ko) 2005-11-28 2008-10-08 젠맵 에이/에스 재조합 １가 항체 및 그의 제조 방법
WO2008013541A2 (en) * 2006-07-25 2008-01-31 Walker Digital, Llc Method and apparatus for conditional payouts in a gaming device
CN101918836B (zh) * 2007-05-08 2014-04-30 皮可贝拉有限责任公司 诊断和治疗前列腺癌和肺癌的方法
JP2009245920A (ja) * 2008-03-11 2009-10-22 Sony Corp 燃料電池、電子機器および燃料電池用緩衝液

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9002480D0 (sv) * 1990-07-23 1990-07-23 Hans Lilja Assay of free and complexed prostate-specific antigen
DE69434470T2 (de) * 1993-02-09 2006-06-22 The Johns Hopkins University School Of Medicine Zellkernmatrixproteine
AU2676197A (en) * 1996-04-16 1997-11-07 Smithkline Beecham Corporation A method for detection of prostate specific antigen used in monitoring and diagnosis of prostate cancer
JP4282906B2 (ja) * 1998-08-10 2009-06-24 アジェンシス，インコーポレイテッド Ｂｐｃ−１：前立腺および膀胱の癌細胞によって発現および分泌がなされる分泌型の脳特異的蛋白質
CA2296792A1 (en) 1999-02-26 2000-08-26 Genset S.A. Expressed sequence tags and encoded human proteins
WO2002059275A2 (en) 2001-01-08 2002-08-01 Millennium Pharmaceuticals, Inc. 39362, a novel human cub domain-containing protein family member and uses thereof
EP1463747A2 (de) 2001-05-03 2004-10-06 Curagen Corporation Neue, an antigene polypeptide bindende antikörper, die antigene codierende nukleinsäuren und verwendungsverfahren
JP2005508631A (ja) 2001-07-17 2005-04-07 インサイト・ゲノミックス・インコーポレイテッド 受容体および膜結合タンパク質

Also Published As

Publication number Publication date
ATE350474T1 (de) 2007-01-15
DE69934694T2 (de) 2007-10-04
AU756452B2 (en) 2003-01-16
IL141061A (en) 2009-12-24
WO2000009691A9 (en) 2000-08-03
WO2000009691A2 (en) 2000-02-24
JP4282906B2 (ja) 2009-06-24
US7785811B2 (en) 2010-08-31
EP1104462B1 (de) 2007-01-03
US20050148012A1 (en) 2005-07-07
US8003758B2 (en) 2011-08-23
IL141061A0 (en) 2002-02-10
EP1104462A2 (de) 2001-06-06
US6277972B1 (en) 2001-08-21
JP2002522076A (ja) 2002-07-23
JP2006320324A (ja) 2006-11-30
US20100168027A1 (en) 2010-07-01
WO2000009691A3 (en) 2000-05-11
JP4637055B2 (ja) 2011-02-23
US20020161212A1 (en) 2002-10-31
CA2338982A1 (en) 2000-02-24
CA2338982C (en) 2011-03-15
AU5556199A (en) 2000-03-06

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