DE69932449D1 - Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs - Google Patents

Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs

Info

Publication number
DE69932449D1
DE69932449D1 DE69932449T DE69932449T DE69932449D1 DE 69932449 D1 DE69932449 D1 DE 69932449D1 DE 69932449 T DE69932449 T DE 69932449T DE 69932449 T DE69932449 T DE 69932449T DE 69932449 D1 DE69932449 D1 DE 69932449D1
Authority
DE
Germany
Prior art keywords
agonists
antagonists
ptbr
treatment
conditions
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69932449T
Other languages
English (en)
Other versions
DE69932449T2 (de
Inventor
Alison Joly
F Schreiner
W Stanton
Tyler White
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Scios LLC
Original Assignee
Scios LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Scios LLC filed Critical Scios LLC
Publication of DE69932449D1 publication Critical patent/DE69932449D1/de
Application granted granted Critical
Publication of DE69932449T2 publication Critical patent/DE69932449T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/68—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving nucleic acids
    • C12Q1/6876—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes
    • C12Q1/6883—Nucleic acid products used in the analysis of nucleic acids, e.g. primers or probes for diseases caused by alterations of genetic material
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q2600/00—Oligonucleotides characterized by their use
    • C12Q2600/158—Expression markers

Landscapes

  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Analytical Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • General Health & Medical Sciences (AREA)
  • Microbiology (AREA)
  • Physics & Mathematics (AREA)
  • Immunology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Molecular Biology (AREA)
  • Pathology (AREA)
  • Biochemistry (AREA)
  • General Engineering & Computer Science (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
DE69932449T 1998-12-18 1999-12-15 Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs Expired - Lifetime DE69932449T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US11300898P 1998-12-18 1998-12-18
US113008P 1998-12-18
US13620399P 1999-05-26 1999-05-26
US136203P 1999-05-26
PCT/US1999/029764 WO2000037086A1 (en) 1998-12-18 1999-12-15 Agonists and antagonists of peripheral-type benzodiazepine receptors

Publications (2)

Publication Number Publication Date
DE69932449D1 true DE69932449D1 (de) 2006-08-31
DE69932449T2 DE69932449T2 (de) 2007-03-15

Family

ID=26810614

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69932449T Expired - Lifetime DE69932449T2 (de) 1998-12-18 1999-12-15 Agonisten und antagonisten von benzodiazepinrezeptoren des peripheren typs

Country Status (7)

Country Link
US (2) US6342495B1 (de)
EP (1) EP1140107B1 (de)
AT (1) ATE333281T1 (de)
AU (1) AU2185100A (de)
DE (1) DE69932449T2 (de)
ES (1) ES2268894T3 (de)
WO (1) WO2000037086A1 (de)

Families Citing this family (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6300235B1 (en) * 1997-06-30 2001-10-09 Siemens Aktiengesellschaft Method of forming multi-level coplanar metal/insulator films using dual damascene with sacrificial flowable oxide
AU2185100A (en) * 1998-12-18 2000-07-12 Scios Inc. Agonists and antagonists of peripheral-type benzodiazepine receptors
JP2002306174A (ja) * 2001-04-11 2002-10-22 Univ Nihon 遺伝子のスクリーニング方法
CA2460117A1 (en) * 2001-09-11 2003-03-20 The Regents Of The University Of Colorado, A Body Corporate Expression profiling in the intact human heart
GB0213614D0 (en) * 2002-06-13 2002-07-24 Novartis Forschungsstiftlung Z Purified PKB Kinae and uses thereof
GB0418877D0 (en) * 2004-08-24 2004-09-29 Univ Edinburgh Heart
JP4362457B2 (ja) * 2005-04-26 2009-11-11 独立行政法人科学技術振興機構 神経因性疼痛治療剤
US20070032480A1 (en) * 2005-06-14 2007-02-08 The Johns Hopkins University Treatment of ischemia-induced arrhythmias
WO2007088528A1 (en) * 2006-02-03 2007-08-09 The Provost, Fellows And Scholars Of The College Of The Holy And Undivided Trinity Of Queen Elizabeth, Near Dublin Microtubule targeting agents
US20100021928A1 (en) * 2006-06-26 2010-01-28 Technion Research & Development Foundation Ltd. Methods and kits for diagnosing cancer
US9075060B2 (en) 2009-06-16 2015-07-07 Technion Research & Development Foundation Limited Methods for diagnosing oral or oral-pharyngeal cancer
CN101936986B (zh) * 2010-08-03 2013-03-06 中国农业大学 一种检测地西泮的方法及其专用化学发光免疫试剂盒
GB202017673D0 (en) * 2020-11-09 2020-12-23 Imperial College Innovations Ltd Treatment of pulmonary arterial hypertensive

Family Cites Families (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2582514B1 (fr) 1985-05-30 1988-02-19 Rhone Poulenc Sante Medicaments a base d'amides, nouveaux amides et leur preparation
FR2599740B1 (fr) 1986-06-05 1988-08-12 Rhone Poulenc Sante Derives de benzo(b)thiophene de benzo(b)furannecarboxamides, leurs procedes de preparation et les medicaments les contenant
DK273689A (da) 1988-06-06 1989-12-07 Sanofi Sa 4-amino-3-carboxyquinoliner og -naphthyridiner, fremgangsmaade til deres fremstilling og anvendelse deraf i laegemidler
FR2659329B1 (fr) 1990-03-09 1994-06-03 Adir Nouveaux derives d'imidazo [1,2-c] quinazoline, leur procede de preparation et les compositions pharmaceutiques les renfermant.
FR2669926A1 (fr) 1990-11-29 1992-06-05 Medgenix Group Sa Ligands specifiques des recepteurs aux benzodiazepines peripheriques.
FR2678269B1 (fr) 1991-06-27 1995-01-13 Synthelabo Derives de 1-(4-chlorophenyl)-2-[4-(2-phenylethyl)piperidin-1-yl]ethanol, leur application et leur preparation en therapeutique.
EP0524846A1 (de) 1991-06-27 1993-01-27 Synthelabo 2-(Piperidin-1-yl)ethanolderivate, ihre Herstellung und ihre Anwendung in der Therapie
US5550124A (en) * 1991-12-10 1996-08-27 University Of Southern California Use of peripheral-type benzodiazpine sites for treatment of CNS trauma or disease
IL117659A (en) 1995-04-13 2000-12-06 Dainippon Pharmaceutical Co Substituted 2-phenyl pyrimidino amino acetamide derivative process for preparing the same and a pharmaceutical composition containing same
US5776946A (en) * 1995-08-28 1998-07-07 Mcgeer; Patrick L. Peripheral benzodiazepine receptor ligands as antiinflammatory agents
WO1999058117A1 (fr) 1998-05-13 1999-11-18 Sanofi-Synthelabo Utilisation de composes reduisant l'apoptose
AU2185100A (en) * 1998-12-18 2000-07-12 Scios Inc. Agonists and antagonists of peripheral-type benzodiazepine receptors

Also Published As

Publication number Publication date
ATE333281T1 (de) 2006-08-15
AU2185100A (en) 2000-07-12
US20030032637A1 (en) 2003-02-13
US6686354B2 (en) 2004-02-03
EP1140107B1 (de) 2006-07-19
WO2000037086A1 (en) 2000-06-29
US6342495B1 (en) 2002-01-29
ES2268894T3 (es) 2007-03-16
DE69932449T2 (de) 2007-03-15
EP1140107A1 (de) 2001-10-10

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