DE69927380D1 - Oxazolidinones zur behandlung von augeninfektionen - Google Patents
Oxazolidinones zur behandlung von augeninfektionenInfo
- Publication number
- DE69927380D1 DE69927380D1 DE69927380T DE69927380T DE69927380D1 DE 69927380 D1 DE69927380 D1 DE 69927380D1 DE 69927380 T DE69927380 T DE 69927380T DE 69927380 T DE69927380 T DE 69927380T DE 69927380 D1 DE69927380 D1 DE 69927380D1
- Authority
- DE
- Germany
- Prior art keywords
- oxazolidinone
- treatment
- eye infections
- treating
- effective amount
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
- IZXIZTKNFFYFOF-UHFFFAOYSA-N 2-Oxazolidone Chemical compound O=C1NCCO1 IZXIZTKNFFYFOF-UHFFFAOYSA-N 0.000 title abstract 2
- 208000001860 Eye Infections Diseases 0.000 title 1
- 208000011323 eye infectious disease Diseases 0.000 title 1
- 241000124008 Mammalia Species 0.000 abstract 1
- 208000015181 infectious disease Diseases 0.000 abstract 1
- 238000000034 method Methods 0.000 abstract 1
- 238000011200 topical administration Methods 0.000 abstract 1
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5375—1,4-Oxazines, e.g. morpholine
- A61K31/5377—1,4-Oxazines, e.g. morpholine not condensed and containing further heterocyclic rings, e.g. timolol
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/41—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having five-membered rings with two or more ring hetero atoms, at least one of which being nitrogen, e.g. tetrazole
- A61K31/42—Oxazoles
- A61K31/422—Oxazoles not condensed and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/4439—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a five-membered ring with nitrogen as a ring hetero atom, e.g. omeprazole
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/435—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with one nitrogen as the only ring hetero atom
- A61K31/44—Non condensed pyridines; Hydrogenated derivatives thereof
- A61K31/4427—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems
- A61K31/444—Non condensed pyridines; Hydrogenated derivatives thereof containing further heterocyclic ring systems containing a six-membered ring with nitrogen as a ring heteroatom, e.g. amrinone
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/495—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with two or more nitrogen atoms as the only ring heteroatoms, e.g. piperazine or tetrazines
- A61K31/496—Non-condensed piperazines containing further heterocyclic rings, e.g. rifampin, thiothixene or sparfloxacin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K31/00—Medicinal preparations containing organic active ingredients
- A61K31/33—Heterocyclic compounds
- A61K31/395—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins
- A61K31/535—Heterocyclic compounds having nitrogen as a ring hetero atom, e.g. guanethidine or rifamycins having six-membered rings with at least one nitrogen and one oxygen as the ring hetero atoms, e.g. 1,2-oxazines
- A61K31/5355—Non-condensed oxazines and containing further heterocyclic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P27/00—Drugs for disorders of the senses
- A61P27/02—Ophthalmic agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/04—Antibacterial agents
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0048—Eye, e.g. artificial tears
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Chemical & Material Sciences (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- General Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Oncology (AREA)
- Ophthalmology & Optometry (AREA)
- Communicable Diseases (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicinal Preparation (AREA)
Applications Claiming Priority (3)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US9276598P | 1998-07-14 | 1998-07-14 | |
| US92765P | 1998-07-14 | ||
| PCT/US1999/012367 WO2000003710A1 (en) | 1998-07-14 | 1999-07-07 | Oxazolidinones to treat eye infections |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| DE69927380D1 true DE69927380D1 (de) | 2005-10-27 |
| DE69927380T2 DE69927380T2 (de) | 2006-07-06 |
Family
ID=22235050
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DE69927380T Expired - Fee Related DE69927380T2 (de) | 1998-07-14 | 1999-07-07 | Oxazolidinone zur behandlung von augeninfektionen |
Country Status (27)
| Country | Link |
|---|---|
| US (2) | US6337329B1 (de) |
| EP (1) | EP1096934B1 (de) |
| JP (1) | JP2002520359A (de) |
| KR (1) | KR20010079530A (de) |
| CN (1) | CN1305374A (de) |
| AT (1) | ATE304886T1 (de) |
| AU (1) | AU740781B2 (de) |
| BG (1) | BG64666B1 (de) |
| BR (1) | BR9912004A (de) |
| CA (1) | CA2334811A1 (de) |
| DE (1) | DE69927380T2 (de) |
| DK (1) | DK1096934T3 (de) |
| EA (1) | EA003274B1 (de) |
| EE (1) | EE200100026A (de) |
| ES (1) | ES2249020T3 (de) |
| HU (1) | HUP0102836A3 (de) |
| ID (1) | ID27276A (de) |
| IL (1) | IL140769A0 (de) |
| NO (1) | NO20010202L (de) |
| NZ (1) | NZ509375A (de) |
| PL (1) | PL345544A1 (de) |
| PT (1) | PT1096934E (de) |
| SG (1) | SG125079A1 (de) |
| SK (1) | SK20332000A3 (de) |
| TR (1) | TR200100066T2 (de) |
| WO (1) | WO2000003710A1 (de) |
| ZA (1) | ZA200100038B (de) |
Families Citing this family (11)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| AR020660A1 (es) * | 1998-09-30 | 2002-05-22 | Alcon Lab Inc | Composiciones antibioticas para el tratamiento de ojos, oidos y nariz |
| AU780671B2 (en) * | 1999-09-13 | 2005-04-07 | Sun Pharma Global Fze | Topical treatment for prevention of ocular infections |
| US6562820B2 (en) | 2000-07-05 | 2003-05-13 | Pharmacia & Upjohn Company | Method for treatment and prevention of mastitis |
| PE20020300A1 (es) * | 2000-08-22 | 2002-05-10 | Pharmacia Corp | Composicion de solucion de un farmaco antibiotico a base de oxazolidinona con mejoramiento de la carga de farmaco |
| AR031135A1 (es) * | 2000-10-10 | 2003-09-10 | Upjohn Co | Composiciones de antibiotico topico para el tratamiento de infecciones oculares |
| US7125568B2 (en) | 2001-08-23 | 2006-10-24 | Sung Michael T | Lipophilic drug compositions |
| US20030069235A1 (en) * | 2001-09-14 | 2003-04-10 | J. Greg Slatter | Treatment for ocular infections |
| JP2005521691A (ja) * | 2002-02-22 | 2005-07-21 | ファルマシア・コーポレーション | シクロデキストリン化合物及び塩化セチルピリジニウムを含有する眼科用抗菌性薬物製剤 |
| TW201043267A (en) * | 2009-03-19 | 2010-12-16 | Intervet Int Bv | In situ constituting a vaccine for administration to a predetermined herd of animals |
| CN101766628B (zh) * | 2010-01-20 | 2012-07-04 | 广东宏盈科技有限公司 | 一种眼科外用抗细菌感染药物 |
| CN108452316B (zh) * | 2012-09-13 | 2022-04-15 | 星法马有限公司 | 眼部感染的治疗或预防方法 |
Family Cites Families (8)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5164510A (en) | 1988-09-15 | 1992-11-17 | The Upjohn Company | 5'Indolinyl-5β-amidomethyloxazolidin-2-ones |
| US5231188A (en) * | 1989-11-17 | 1993-07-27 | The Upjohn Company | Tricyclic [6.5.51]-fused oxazolidinone antibacterial agents |
| DK0610265T3 (da) | 1991-11-01 | 1997-06-09 | Upjohn Co | Substituerede aryl- og heteroarylphenyloxazolidioner, som kan anvendes som antibakterielle midler |
| US5688792A (en) * | 1994-08-16 | 1997-11-18 | Pharmacia & Upjohn Company | Substituted oxazine and thiazine oxazolidinone antimicrobials |
| WO1995014684A1 (en) | 1993-11-22 | 1995-06-01 | The Upjohn Company | Esters of substituted-hydroxyacetyl piperazine phenyl oxazolidinones |
| DE4425613A1 (de) * | 1994-07-20 | 1996-01-25 | Bayer Ag | 5-gliedrige Heteroaryl-oxazolidinone |
| DE4425612A1 (de) * | 1994-07-20 | 1996-04-04 | Bayer Ag | 6-gliedrige stickstoffhaltige Heteroaryl-oxazolidinone |
| DE69739907D1 (de) * | 1996-05-31 | 2010-07-22 | Scripps Research Inst | 3 vermittelter angiogenesis hemmers |
-
1999
- 1999-07-07 PT PT99933483T patent/PT1096934E/pt unknown
- 1999-07-07 HU HU0102836A patent/HUP0102836A3/hu unknown
- 1999-07-07 IL IL14076999A patent/IL140769A0/xx unknown
- 1999-07-07 DE DE69927380T patent/DE69927380T2/de not_active Expired - Fee Related
- 1999-07-07 AU AU49530/99A patent/AU740781B2/en not_active Ceased
- 1999-07-07 CN CN99807427A patent/CN1305374A/zh active Pending
- 1999-07-07 EP EP99933483A patent/EP1096934B1/de not_active Expired - Lifetime
- 1999-07-07 EE EEP200100026A patent/EE200100026A/xx unknown
- 1999-07-07 ID IDW20002687A patent/ID27276A/id unknown
- 1999-07-07 WO PCT/US1999/012367 patent/WO2000003710A1/en not_active Application Discontinuation
- 1999-07-07 US US09/349,430 patent/US6337329B1/en not_active Expired - Fee Related
- 1999-07-07 SK SK2033-2000A patent/SK20332000A3/sk unknown
- 1999-07-07 JP JP2000559845A patent/JP2002520359A/ja not_active Withdrawn
- 1999-07-07 KR KR1020017000567A patent/KR20010079530A/ko not_active Application Discontinuation
- 1999-07-07 CA CA002334811A patent/CA2334811A1/en not_active Abandoned
- 1999-07-07 NZ NZ509375A patent/NZ509375A/en unknown
- 1999-07-07 DK DK99933483T patent/DK1096934T3/da active
- 1999-07-07 AT AT99933483T patent/ATE304886T1/de not_active IP Right Cessation
- 1999-07-07 SG SG200300091A patent/SG125079A1/en unknown
- 1999-07-07 TR TR2001/00066T patent/TR200100066T2/xx unknown
- 1999-07-07 BR BR9912004-6A patent/BR9912004A/pt not_active Application Discontinuation
- 1999-07-07 ES ES99933483T patent/ES2249020T3/es not_active Expired - Lifetime
- 1999-07-07 PL PL99345544A patent/PL345544A1/xx unknown
- 1999-07-07 EA EA200100133A patent/EA003274B1/ru unknown
-
2001
- 2001-01-02 ZA ZA200100038A patent/ZA200100038B/en unknown
- 2001-01-10 BG BG105142A patent/BG64666B1/bg unknown
- 2001-01-12 NO NO20010202A patent/NO20010202L/no not_active Application Discontinuation
- 2001-09-19 US US09/955,679 patent/US6740652B2/en not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| 8364 | No opposition during term of opposition | ||
| 8339 | Ceased/non-payment of the annual fee |