DE69923580D1 - Verstärkte katalysierte reporterabscheidung - Google Patents

Verstärkte katalysierte reporterabscheidung

Info

Publication number
DE69923580D1
DE69923580D1 DE69923580T DE69923580T DE69923580D1 DE 69923580 D1 DE69923580 D1 DE 69923580D1 DE 69923580 T DE69923580 T DE 69923580T DE 69923580 T DE69923580 T DE 69923580T DE 69923580 D1 DE69923580 D1 DE 69923580D1
Authority
DE
Germany
Prior art keywords
cooh
reinforced
enhancing
heteroatom alkyl
inorganic salt
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69923580T
Other languages
English (en)
Other versions
DE69923580T2 (de
Inventor
Norman Bobrow
Edwin Adler
Aaron Roth
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
PerkinElmer Health Sciences Inc
Original Assignee
NEN Life Science Products Inc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by NEN Life Science Products Inc filed Critical NEN Life Science Products Inc
Application granted granted Critical
Publication of DE69923580D1 publication Critical patent/DE69923580D1/de
Publication of DE69923580T2 publication Critical patent/DE69923580T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12Q—MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28—Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C235/00—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms
    • C07C235/02—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton
    • C07C235/04—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated
    • C07C235/18—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides
    • C07C235/20—Carboxylic acid amides, the carbon skeleton of the acid part being further substituted by oxygen atoms having carbon atoms of carboxamide groups bound to acyclic carbon atoms and singly-bound oxygen atoms bound to the same carbon skeleton the carbon skeleton being acyclic and saturated having at least one of the singly-bound oxygen atoms further bound to a carbon atom of a six-membered aromatic ring, e.g. phenoxyacetamides having the nitrogen atoms of the carboxamide groups bound to hydrogen atoms or to acyclic carbon atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • General Engineering & Computer Science (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Physics & Mathematics (AREA)
  • Biochemistry (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biotechnology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Luminescent Compositions (AREA)
  • Inert Electrodes (AREA)
  • Carbon And Carbon Compounds (AREA)
  • Reinforced Plastic Materials (AREA)
DE69923580T 1998-11-09 1999-11-08 Verstärkte katalysierte reporterabscheidung Expired - Lifetime DE69923580T2 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US10765498P 1998-11-09 1998-11-09
US107654P 1998-11-09
US09/434,742 US6372937B1 (en) 1998-11-09 1999-11-05 Enhanced catalyzed reporter deposition
US434742 1999-11-05
PCT/US1999/026327 WO2000028077A1 (en) 1998-11-09 1999-11-08 Enhanced catalyzed reporter deposition

Publications (2)

Publication Number Publication Date
DE69923580D1 true DE69923580D1 (de) 2005-03-10
DE69923580T2 DE69923580T2 (de) 2006-01-05

Family

ID=26805004

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69923580T Expired - Lifetime DE69923580T2 (de) 1998-11-09 1999-11-08 Verstärkte katalysierte reporterabscheidung

Country Status (8)

Country Link
US (2) US6372937B1 (de)
EP (1) EP1129214B1 (de)
AT (1) ATE288497T1 (de)
AU (1) AU768695B2 (de)
CA (1) CA2351579C (de)
DE (1) DE69923580T2 (de)
ES (1) ES2237184T3 (de)
WO (1) WO2000028077A1 (de)

Families Citing this family (22)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9400034D0 (sv) * 1994-01-06 1994-01-06 Glycorex Ab Laktosaminderivat
US6518036B1 (en) * 1999-03-17 2003-02-11 Nen Life Science Products, Inc. Method of permanent fluorescent assay
JP2002280842A (ja) * 2001-03-21 2002-09-27 Hitachi Ltd 電力増幅器モジュール
EP1381349A4 (de) * 2001-04-27 2004-09-29 Gen Hospital Corp Tyrosinasebestimmung
US6617125B2 (en) * 2001-06-29 2003-09-09 Perkinelmer Life Sciences, Inc. Compositions for enhanced catalyzed reporter deposition
US7354706B2 (en) * 2003-09-09 2008-04-08 The Regents Of The University Of Colorado, A Body Corporate Use of photopolymerization for amplification and detection of a molecular recognition event
US20090163375A1 (en) 2003-09-09 2009-06-25 Bowman Christopher N Use of Photopolymerization for Amplification and Detection of a Molecular Recognition Event
PL209602B1 (pl) 2005-10-20 2011-09-30 Inst Chemii Bioorg Pan Sposób otrzymywania amidu kwasu 3-(4-hydroksyfenylo)propanowego
CA2698390C (en) 2007-09-18 2018-05-22 Dako Denmark A/S A rapid and sensitive method for detection of biological targets
US20090137405A1 (en) * 2007-11-16 2009-05-28 Christopher Bowman Detection of nucleic acid biomarkers using polymerization-based amplification
JP5721639B2 (ja) 2009-02-19 2015-05-20 ダコ・デンマーク・エー／エス 分子標的の検出のための方法と化合物
CN104714007B (zh) * 2009-10-20 2017-04-12 丹麦达科有限公司 单个靶实体的免疫化学检测
AU2011274369A1 (en) 2010-07-02 2012-12-06 Ventana Medical Systems, Inc. Hapten conjugates for target detection
BR112013014360B8 (pt) 2010-12-30 2020-12-15 Ventana Med Syst Inc método para detectar um alvo em uma amostra e kit
DK2831587T3 (en) 2012-03-27 2018-07-23 Ventana Med Syst Inc Signaling conjugates and methods of use
JP6762296B2 (ja) 2014-10-02 2020-09-30 ヴェンタナ メディカル システムズ， インク． ポリマー及びポリマーを含むコンジュゲート
AU2016349644B2 (en) 2015-11-06 2022-11-24 Ventana Medical Systems, Inc. Representative diagnostics
EP3710820A1 (de) 2017-11-13 2020-09-23 F. Hoffmann-La Roche AG Vorrichtungen zur probenanalyse mittels epitachophorese
WO2020072348A1 (en) 2018-10-01 2020-04-09 Ventana Medical Systems, Inc. Methods and systems for predicting response to pd-1 axis directed therapeutics
WO2020074742A1 (en) 2018-10-12 2020-04-16 F. Hoffmann-La Roche Ag Detection methods for epitachophoresis workflow automation
JP7441243B2 (ja) 2019-05-14 2024-02-29 エフ． ホフマン－ラ ロシュ アーゲー 試料分析のための装置および方法
WO2021067475A1 (en) 2019-09-30 2021-04-08 Akoya Biosciences, Inc. Multiplexed imaging with enzyme mediated amplification

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4521511A (en) 1982-09-22 1985-06-04 Enzyme Technology Company Catalyzed colorimetric and fluorometric substrates for peroxidase enzyme determinations
DE3463395D1 (en) 1983-02-11 1987-06-04 Nat Res Dev Enhanced luminescent or luminometric assay
GB8420053D0 (en) 1984-08-07 1984-09-12 Secr Social Service Brit Enhanced luminescent/luminometric assay
US4835101A (en) 1986-02-10 1989-05-30 Kallestad Diagnostics, Inc. Luminescent analyses with enhanced storage stability
US5196306A (en) 1989-03-29 1993-03-23 E. I. Du Pont De Nemours And Company Method for the detection or quantitation of an analyte using an analyte dependent enzyme activation system
US5629168A (en) 1992-02-10 1997-05-13 British Technology Group Limited Chemiluminescent enhancers
US5688966A (en) 1996-07-26 1997-11-18 E. I. Du Pont De Nemours And Company Compounds and method for synthesizing sulfoindocyanine dyes
US5863748A (en) 1997-03-14 1999-01-26 New Life Science Products, Inc. p-Hydroxycinnamoyl-containing substrates for an analyte dependent enzyme activation system
US6518036B1 (en) * 1999-03-17 2003-02-11 Nen Life Science Products, Inc. Method of permanent fluorescent assay

Also Published As

Publication number Publication date
CA2351579C (en) 2010-01-19
CA2351579A1 (en) 2000-05-18
DE69923580T2 (de) 2006-01-05
EP1129214B1 (de) 2005-02-02
EP1129214A4 (de) 2002-06-19
WO2000028077A1 (en) 2000-05-18
US6372937B1 (en) 2002-04-16
US6593100B2 (en) 2003-07-15
AU768695B2 (en) 2004-01-08
ATE288497T1 (de) 2005-02-15
EP1129214A1 (de) 2001-09-05
ES2237184T3 (es) 2005-07-16
US20010039035A1 (en) 2001-11-08
AU1611500A (en) 2000-05-29

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Legal Events

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