DE69921011D1 - Neue (3,4,7,8,9,10) hexahydro-6, 10-dioxo-6H-pyridazino /1, 2-a/ /1, 2/ Diazepin-1-Carbonsäure-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung pharmazeutischer Wirkstoffe - Google Patents

Neue (3,4,7,8,9,10) hexahydro-6, 10-dioxo-6H-pyridazino /1, 2-a/ /1, 2/ Diazepin-1-Carbonsäure-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung pharmazeutischer Wirkstoffe

Info

Publication number
DE69921011D1
DE69921011D1 DE1999621011 DE69921011T DE69921011D1 DE 69921011 D1 DE69921011 D1 DE 69921011D1 DE 1999621011 DE1999621011 DE 1999621011 DE 69921011 T DE69921011 T DE 69921011T DE 69921011 D1 DE69921011 D1 DE 69921011D1
Authority
DE
Germany
Prior art keywords
pyridazino
diazepine
dioxo
carboxylic acid
hexahydro
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE1999621011
Other languages
English (en)
Other versions
DE69921011T2 (de
Inventor
Francis Brion
Veronique Crocq
Patrick Roussel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Aventis Pharma SA
Original Assignee
Aventis Pharma SA
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma SA filed Critical Aventis Pharma SA
Publication of DE69921011D1 publication Critical patent/DE69921011D1/de
Application granted granted Critical
Publication of DE69921011T2 publication Critical patent/DE69921011T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DE69921011T 1998-04-27 1999-04-26 Neue (3,4,7,8,9,10) hexahydro-6, 10-dioxo-6H-pyridazino /1, 2-a/ /1, 2/ Diazepin-1-Carbonsäure-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung pharmazeutischer Wirkstoffe Expired - Lifetime DE69921011T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9805242A FR2777888B1 (fr) 1998-04-27 1998-04-27 Nouveaux derives de l'acide (3,4,7,8,9,10-hexahydro-6,10- dioxo-6h-pyridazino[1,2-a][1,2]diazepine-1-carboxylique, leur procede de preparation et leur application a la preparation de medicaments
FR9805242 1998-04-27

Publications (2)

Publication Number Publication Date
DE69921011D1 true DE69921011D1 (de) 2004-11-18
DE69921011T2 DE69921011T2 (de) 2005-10-27

Family

ID=9525704

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69921011T Expired - Lifetime DE69921011T2 (de) 1998-04-27 1999-04-26 Neue (3,4,7,8,9,10) hexahydro-6, 10-dioxo-6H-pyridazino /1, 2-a/ /1, 2/ Diazepin-1-Carbonsäure-Derivate, Verfahren zu deren Herstellung und deren Verwendung zur Herstellung pharmazeutischer Wirkstoffe

Country Status (9)

Country Link
US (2) US6258947B1 (de)
EP (1) EP0955310B1 (de)
JP (1) JP2000001489A (de)
AT (1) ATE279434T1 (de)
DE (1) DE69921011T2 (de)
DK (1) DK0955310T3 (de)
ES (1) ES2229641T3 (de)
FR (1) FR2777888B1 (de)
PT (1) PT955310E (de)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6177565B1 (en) 1998-08-19 2001-01-23 Vertex Pharmaceuticals Inc. Process for synthesizing piperazic acid
US6201118B1 (en) 1998-08-19 2001-03-13 Vertex Pharmaceuticals Inc. Process for forming an N-acylated, N,N-containing bicyclic ring from piperazic acid or an ester thereof especially useful as an intermediate in the manufacture of a caspase inhibitor
US6451373B1 (en) * 2000-08-04 2002-09-17 Advanced Cardiovascular Systems, Inc. Method of forming a therapeutic coating onto a surface of an implantable prosthesis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204261B1 (en) * 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
GB2128984B (en) * 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds
US5552397A (en) * 1992-05-18 1996-09-03 E. R. Squibb & Sons, Inc. Substituted azepinone dual inhibitors of angiotensin converting enzyme and neutral exdopeptidase
ES2164056T3 (es) * 1992-05-18 2002-02-16 Hoffmann La Roche Hidrogenacion asimetrica.

Also Published As

Publication number Publication date
PT955310E (pt) 2005-01-31
JP2000001489A (ja) 2000-01-07
US6258947B1 (en) 2001-07-10
DK0955310T3 (da) 2005-02-14
ATE279434T1 (de) 2004-10-15
DE69921011T2 (de) 2005-10-27
EP0955310B1 (de) 2004-10-13
FR2777888B1 (fr) 2004-07-16
US20010002422A1 (en) 2001-05-31
US6433164B2 (en) 2002-08-13
EP0955310A1 (de) 1999-11-10
FR2777888A1 (fr) 1999-10-29
ES2229641T3 (es) 2005-04-16

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Legal Events

Date Code Title Description
8364 No opposition during term of opposition
8328 Change in the person/name/address of the agent

Representative=s name: PFENNING MEINIG & PARTNER GBR, 80339 MUENCHEN

8328 Change in the person/name/address of the agent

Representative=s name: MAIWALD PATENTANWALTSGESELLSCHAFT MBH, 80335 MUENC