DK0955310T3 - Hidtil ukendte (3,4,7,8,9,10)-hexahydro-6,10-dioxo-6H-pyridazino[1,2-a][1,2]diazepin-1-carboxylsyrederivater, fremgangsmåde til fremstilling af disse og anvendelse af disse til fremstilling af lægemidler - Google Patents

Hidtil ukendte (3,4,7,8,9,10)-hexahydro-6,10-dioxo-6H-pyridazino[1,2-a][1,2]diazepin-1-carboxylsyrederivater, fremgangsmåde til fremstilling af disse og anvendelse af disse til fremstilling af lægemidler

Info

Publication number
DK0955310T3
DK0955310T3 DK99401019T DK99401019T DK0955310T3 DK 0955310 T3 DK0955310 T3 DK 0955310T3 DK 99401019 T DK99401019 T DK 99401019T DK 99401019 T DK99401019 T DK 99401019T DK 0955310 T3 DK0955310 T3 DK 0955310T3
Authority
DK
Denmark
Prior art keywords
pyridazino
diazepine
dioxo
carboxylic acid
hexahydro
Prior art date
Application number
DK99401019T
Other languages
English (en)
Inventor
Francis Brion
Veronique Crocq
Patrick Roussel
Original Assignee
Aventis Pharma Sa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Aventis Pharma Sa filed Critical Aventis Pharma Sa
Application granted granted Critical
Publication of DK0955310T3 publication Critical patent/DK0955310T3/da

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06139—Dipeptides with the first amino acid being heterocyclic

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Genetics & Genomics (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
DK99401019T 1998-04-27 1999-04-26 Hidtil ukendte (3,4,7,8,9,10)-hexahydro-6,10-dioxo-6H-pyridazino[1,2-a][1,2]diazepin-1-carboxylsyrederivater, fremgangsmåde til fremstilling af disse og anvendelse af disse til fremstilling af lægemidler DK0955310T3 (da)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
FR9805242A FR2777888B1 (fr) 1998-04-27 1998-04-27 Nouveaux derives de l'acide (3,4,7,8,9,10-hexahydro-6,10- dioxo-6h-pyridazino[1,2-a][1,2]diazepine-1-carboxylique, leur procede de preparation et leur application a la preparation de medicaments
EP99401019A EP0955310B1 (fr) 1998-04-27 1999-04-26 Nouveaux dérivés de l'acide (3,4,7,8,9,10) -hexahydro-6,10-dioxo-6H-pyridazino /1,2-a/ /1,2/ diazépine-1-carboxylique, leur procédé de préparation et leur application à la préparation de médicaments

Publications (1)

Publication Number Publication Date
DK0955310T3 true DK0955310T3 (da) 2005-02-14

Family

ID=9525704

Family Applications (1)

Application Number Title Priority Date Filing Date
DK99401019T DK0955310T3 (da) 1998-04-27 1999-04-26 Hidtil ukendte (3,4,7,8,9,10)-hexahydro-6,10-dioxo-6H-pyridazino[1,2-a][1,2]diazepin-1-carboxylsyrederivater, fremgangsmåde til fremstilling af disse og anvendelse af disse til fremstilling af lægemidler

Country Status (9)

Country Link
US (2) US6258947B1 (da)
EP (1) EP0955310B1 (da)
JP (1) JP2000001489A (da)
AT (1) ATE279434T1 (da)
DE (1) DE69921011T2 (da)
DK (1) DK0955310T3 (da)
ES (1) ES2229641T3 (da)
FR (1) FR2777888B1 (da)
PT (1) PT955310E (da)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6201118B1 (en) 1998-08-19 2001-03-13 Vertex Pharmaceuticals Inc. Process for forming an N-acylated, N,N-containing bicyclic ring from piperazic acid or an ester thereof especially useful as an intermediate in the manufacture of a caspase inhibitor
US6177565B1 (en) 1998-08-19 2001-01-23 Vertex Pharmaceuticals Inc. Process for synthesizing piperazic acid
US6451373B1 (en) * 2000-08-04 2002-09-17 Advanced Cardiovascular Systems, Inc. Method of forming a therapeutic coating onto a surface of an implantable prosthesis

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US6204261B1 (en) * 1995-12-20 2001-03-20 Vertex Pharmaceuticals Incorporated Inhibitors of interleukin-1β Converting enzyme inhibitors
GB2128984B (en) * 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds
US5552397A (en) * 1992-05-18 1996-09-03 E. R. Squibb & Sons, Inc. Substituted azepinone dual inhibitors of angiotensin converting enzyme and neutral exdopeptidase
DE59310189D1 (de) * 1992-05-18 2001-08-23 Hoffmann La Roche Asymmetrische Hydrierung

Also Published As

Publication number Publication date
JP2000001489A (ja) 2000-01-07
US6258947B1 (en) 2001-07-10
FR2777888A1 (fr) 1999-10-29
ES2229641T3 (es) 2005-04-16
FR2777888B1 (fr) 2004-07-16
EP0955310A1 (fr) 1999-11-10
US6433164B2 (en) 2002-08-13
US20010002422A1 (en) 2001-05-31
DE69921011D1 (de) 2004-11-18
ATE279434T1 (de) 2004-10-15
EP0955310B1 (fr) 2004-10-13
DE69921011T2 (de) 2005-10-27
PT955310E (pt) 2005-01-31

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