DE69919713D1 - Pharmazeutische zubereitung mit verzögerter wirkstofffreisetzung von phenytoin natrium - Google Patents
Pharmazeutische zubereitung mit verzögerter wirkstofffreisetzung von phenytoin natriumInfo
- Publication number
- DE69919713D1 DE69919713D1 DE69919713T DE69919713T DE69919713D1 DE 69919713 D1 DE69919713 D1 DE 69919713D1 DE 69919713 T DE69919713 T DE 69919713T DE 69919713 T DE69919713 T DE 69919713T DE 69919713 D1 DE69919713 D1 DE 69919713D1
- Authority
- DE
- Germany
- Prior art keywords
- coating
- active ingredient
- phenytoin sodium
- active substance
- pharmaceutical preparation
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
- A61K9/5078—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings with drug-free core
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5073—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals having two or more different coatings optionally including drug-containing subcoatings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5026—Organic macromolecular compounds obtained by reactions only involving carbon-to-carbon unsaturated bonds, e.g. polyvinyl pyrrolidone, poly(meth)acrylates
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US111188 | 1998-07-07 | ||
US09/111,188 US5968554A (en) | 1998-07-07 | 1998-07-07 | Sustained release pharmaceutical preparation |
US09/338,716 US6312728B1 (en) | 1998-07-07 | 1999-06-23 | Sustained release pharmaceutical preparation |
US338716 | 1999-06-23 | ||
PCT/US1999/014204 WO2000001369A1 (en) | 1998-07-07 | 1999-06-25 | Sustained release pharmaceutical preparation |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69919713D1 true DE69919713D1 (de) | 2004-09-30 |
DE69919713T2 DE69919713T2 (de) | 2005-09-22 |
Family
ID=26808709
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69919713T Expired - Lifetime DE69919713T2 (de) | 1998-07-07 | 1999-06-25 | Pharmazeutische zubereitung mit verzögerter wirkstofffreisetzung von phenytoin natrium |
Country Status (10)
Country | Link |
---|---|
US (1) | US6312728B1 (de) |
EP (1) | EP1094790B9 (de) |
JP (1) | JP2003524592A (de) |
AT (1) | ATE274344T1 (de) |
AU (1) | AU5084299A (de) |
CA (1) | CA2337046C (de) |
DE (1) | DE69919713T2 (de) |
ES (1) | ES2226412T3 (de) |
IL (1) | IL140761A0 (de) |
WO (1) | WO2000001369A1 (de) |
Families Citing this family (47)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
SE9803871D0 (sv) * | 1998-11-11 | 1998-11-11 | Pharmacia & Upjohn Ab | Therapeutic method and formulation |
US20030068356A1 (en) * | 2001-07-10 | 2003-04-10 | Pather S. Indiran | Sequential drug delivery systems |
US6572889B1 (en) | 2002-03-07 | 2003-06-03 | Noveon Ip Holdings Corp. | Controlled release solid dosage carbamazepine formulations |
US20040043067A1 (en) * | 2002-06-19 | 2004-03-04 | Salamone Joseph C. | Fluorosiloxane matrix controlled diffusion drug delivery systems |
AR040682A1 (es) | 2002-07-25 | 2005-04-13 | Pharmacia Corp | Forma de dosificacion una vez al dia de pramipexol |
JP2006507298A (ja) * | 2002-10-30 | 2006-03-02 | ファルマシア コーポレーション | 経口持続放出型錠剤、ならびにその製造法および使用法 |
US7988993B2 (en) * | 2002-12-09 | 2011-08-02 | Andrx Pharmaceuticals, Inc. | Oral controlled release dosage form |
US20040253293A1 (en) * | 2003-06-16 | 2004-12-16 | Afshin Shafiee | Rate controlled release of a pharmaceutical agent in a biodegradable device |
JP2007507491A (ja) * | 2003-09-29 | 2007-03-29 | シージェー コーポレーション | 徐放性製剤 |
US7670624B2 (en) * | 2004-01-29 | 2010-03-02 | Astella Pharma Inc. | Gastrointestinal-specific multiple drug release system |
WO2005117697A2 (en) | 2004-05-28 | 2005-12-15 | Narayanan Ramasubramanian | Unified indigestion package and process for patient compliance with prescribed medication regimen |
US9592197B2 (en) * | 2004-12-16 | 2017-03-14 | Sovereign Pharmaceuticals, Llc | Dosage form containing diphenhydramine and another drug |
US20070003622A1 (en) * | 2004-12-16 | 2007-01-04 | Sovereign Pharmaceuticals, Ltd. | Diphenhydramine containing dosage form |
US20060034910A1 (en) * | 2004-08-09 | 2006-02-16 | Sanjay Patel | Pharmaceutical composition for extended release of phenytoin sodium |
UA88477C2 (ru) | 2004-08-13 | 2009-10-26 | Бёрингер Ингельхайм Интернациональ Гмбх | Композиция пеллеты пролонгированного высвобождения, которая содержит прамипексол или его фармацевтически приемлемую соль, способ ее изготовления и ее применение |
PL1781260T5 (pl) | 2004-08-13 | 2014-09-30 | Boehringer Ingelheim Int | Preparat tabletkowy o przedłużonym uwalnianiu zawierający pramipeksol lub jego farmaceutycznie dopuszczalną sól, sposób wytwarzania tego preparatu i jego zastosowanie |
US20060134175A1 (en) * | 2004-12-22 | 2006-06-22 | Stephen Bartels | Drug eluting pharmaceutical delivery system for treatment of ocular disease and method of use |
US7529255B2 (en) * | 2005-04-21 | 2009-05-05 | Microsoft Corporation | Peer-to-peer multicasting using multiple transport protocols |
JP5044572B2 (ja) | 2006-02-13 | 2012-10-10 | ヴァンダ ファーマシューティカルズ インコーポレイテッド | イミダゾリルアルキル−ピリジンの安定な投薬製剤 |
JP5228359B2 (ja) * | 2007-04-12 | 2013-07-03 | ニプロ株式会社 | 主薬粒子及びその製造方法ならびに口腔内崩壊錠 |
DK2152250T3 (da) * | 2007-05-07 | 2019-12-09 | Evonik Degussa Gmbh | Faste doseringsformer, der omfatter et enterisk overtræk, med accelereret lægemiddelfrigivelse |
CA2709103C (en) | 2007-12-13 | 2017-01-17 | Vanda Pharmaceuticals Inc. | Method and composition for treating an alpha adrenoceptor-mediated condition |
PL2222300T3 (pl) | 2007-12-13 | 2015-02-27 | Vanda Pharmaceuticals Inc | Sposób i skład preparatu do leczenia chorób z udziałem receptorów serotoniny |
US20090214665A1 (en) * | 2008-02-26 | 2009-08-27 | Lai Felix S | Controlled Release Muscarinic Receptor Antagonist Formulation |
US8663671B2 (en) * | 2009-11-05 | 2014-03-04 | Philip Morris Usa Inc. | Methods and compositions for producing hydrogel capsules coated for low permeability and physical integrity |
US8999393B1 (en) | 2013-01-09 | 2015-04-07 | Edgemont Pharmaceuticals Llc | Sustained release formulations of lorazepam |
US20230355689A1 (en) | 2019-12-27 | 2023-11-09 | Evelo Biosciences, Inc. | Solid dosage forms containing bacteria and microbial extracellular vesicles |
WO2021146523A1 (en) | 2020-01-17 | 2021-07-22 | Evelo Biosciences, Inc. | Solid dosage forms with improved disintegration profiles |
KR20230004619A (ko) | 2020-04-17 | 2023-01-06 | 에벨로 바이오사이언시즈, 인크. | 붕해 프로파일이 개선된 고체 투여 형태 |
CA3192766A1 (en) | 2020-09-18 | 2022-03-24 | Syed Altaf | Solid dosage forms of bacteria |
CN116648253A (zh) | 2020-10-29 | 2023-08-25 | 伊夫罗生物科学公司 | 包含螺旋藻组分的组合物 |
TW202237155A (zh) | 2020-12-14 | 2022-10-01 | 美商艾弗洛生物科技股份有限公司 | 細胞外囊泡製劑 |
EP4267154A1 (de) | 2020-12-22 | 2023-11-01 | Evelo Biosciences, Inc. | Zusammensetzungen mit tierhämoglobin |
EP4284400A1 (de) | 2021-01-26 | 2023-12-06 | Evelo Biosciences, Inc. | Prevotella extrazelluläre vesikelzubereitungen |
EP4297762A1 (de) | 2021-02-26 | 2024-01-03 | Evelo Biosciences, Inc. | Zusammensetzungen und verfahren zur reduzierung der cytokinexpression |
WO2022187578A1 (en) | 2021-03-05 | 2022-09-09 | Evelo Biosciences, Inc. | Solid dosage forms |
TW202304415A (zh) | 2021-04-08 | 2023-02-01 | 美商艾弗洛生物科技股份有限公司 | 含有細菌的藥物製劑 |
WO2022221183A1 (en) | 2021-04-12 | 2022-10-20 | Evelo Biosciences, Inc. | Fournierella extracellular vesicle preparations |
WO2022251166A2 (en) | 2021-05-25 | 2022-12-01 | Evelo Biosciences, Inc. | Bacterial compositions comprising soy hemoglobin |
WO2023049268A1 (en) | 2021-09-24 | 2023-03-30 | Evelo Biosciences, Inc. | Solid dosage forms containing bacteria and microbial extracellular vesicles |
WO2023114296A2 (en) | 2021-12-14 | 2023-06-22 | Evelo Biosciences, Inc. | Extracellular vesicle preparations |
WO2023114295A1 (en) | 2021-12-14 | 2023-06-22 | Evelo Biosciences, Inc. | Veillonella parvula bacteria extracellular vesicle preparations |
WO2023114300A1 (en) | 2021-12-14 | 2023-06-22 | Evelo Biosciences, Inc. | Fournierella massiliensis bacteria extracellular vesicle preparations |
WO2023146843A1 (en) | 2022-01-25 | 2023-08-03 | Evelo Biosciences, Inc. | Extracellular vesicle compositions and methods of use |
WO2023183396A1 (en) | 2022-03-22 | 2023-09-28 | Evelo Biosciences, Inc. | Compositions and methods of treating inflammation using prevotella histicola |
WO2023200837A1 (en) | 2022-04-13 | 2023-10-19 | Evelo Biosciences, Inc. | Compositions and methods of treating inflammation using prevotella histicola |
WO2023239728A1 (en) | 2022-06-07 | 2023-12-14 | Evelo Biosciences, Inc. | Compositions and methods of treating inflammation using prevotella histicola extracellular vesicles |
Family Cites Families (13)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US4994260A (en) | 1982-05-28 | 1991-02-19 | Astra Lakemedel Aktiebolag | Pharmaceutical mixture |
US5238686A (en) | 1986-03-27 | 1993-08-24 | Kinaform Technology, Inc. | Sustained-release pharmaceutical preparation |
US4968508A (en) | 1987-02-27 | 1990-11-06 | Eli Lilly And Company | Sustained release matrix |
US5540945A (en) * | 1989-05-11 | 1996-07-30 | Chugai Seiyaku Kabushiki Kaisha | Pharmaceutical preparations for oral administration that are adapted to release the drug at appropriate sites in the intestines |
ES2064564T3 (es) * | 1989-09-21 | 1995-02-01 | American Cyanamid Co | Sistema de liberacion pulsatil de dosis unitaria diaria de minociclina. |
US5368861A (en) * | 1989-10-26 | 1994-11-29 | Nippon Shinyaku Co., Ltd. | Gastric preparation with sustained release |
US5229131A (en) | 1990-02-05 | 1993-07-20 | University Of Michigan | Pulsatile drug delivery system |
US5188836A (en) | 1990-07-27 | 1993-02-23 | Warner-Lambert Company | Sustained release formulations |
US5102668A (en) | 1990-10-05 | 1992-04-07 | Kingaform Technology, Inc. | Sustained release pharmaceutical preparation using diffusion barriers whose permeabilities change in response to changing pH |
US5286493A (en) | 1992-01-27 | 1994-02-15 | Euroceltique, S.A. | Stabilized controlled release formulations having acrylic polymer coating |
DE19630035A1 (de) * | 1996-07-25 | 1998-01-29 | Asta Medica Ag | Tramadol Multiple Unit Formulierungen |
US5885616A (en) * | 1997-08-18 | 1999-03-23 | Impax Pharmaceuticals, Inc. | Sustained release drug delivery system suitable for oral administration |
US5968554A (en) * | 1998-07-07 | 1999-10-19 | Cascade Development, Inc. A Subsidiary Of Cardinal Health, Inc. | Sustained release pharmaceutical preparation |
-
1999
- 1999-06-23 US US09/338,716 patent/US6312728B1/en not_active Expired - Lifetime
- 1999-06-25 JP JP2000557816A patent/JP2003524592A/ja active Pending
- 1999-06-25 DE DE69919713T patent/DE69919713T2/de not_active Expired - Lifetime
- 1999-06-25 EP EP99935347A patent/EP1094790B9/de not_active Expired - Lifetime
- 1999-06-25 WO PCT/US1999/014204 patent/WO2000001369A1/en active IP Right Grant
- 1999-06-25 CA CA002337046A patent/CA2337046C/en not_active Expired - Lifetime
- 1999-06-25 AT AT99935347T patent/ATE274344T1/de not_active IP Right Cessation
- 1999-06-25 ES ES99935347T patent/ES2226412T3/es not_active Expired - Lifetime
- 1999-06-25 IL IL14076199A patent/IL140761A0/xx unknown
- 1999-06-25 AU AU50842/99A patent/AU5084299A/en not_active Abandoned
Also Published As
Publication number | Publication date |
---|---|
DE69919713T2 (de) | 2005-09-22 |
EP1094790A4 (de) | 2003-03-12 |
AU5084299A (en) | 2000-01-24 |
WO2000001369A1 (en) | 2000-01-13 |
IL140761A0 (en) | 2002-02-10 |
CA2337046A1 (en) | 2000-01-13 |
JP2003524592A (ja) | 2003-08-19 |
ES2226412T3 (es) | 2005-03-16 |
EP1094790B9 (de) | 2005-05-04 |
ATE274344T1 (de) | 2004-09-15 |
EP1094790B1 (de) | 2004-08-25 |
CA2337046C (en) | 2005-08-16 |
EP1094790A1 (de) | 2001-05-02 |
US6312728B1 (en) | 2001-11-06 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |