DE69915478D1 - Geschmacksmaskierung mittels croscarmellose - Google Patents
Geschmacksmaskierung mittels croscarmelloseInfo
- Publication number
- DE69915478D1 DE69915478D1 DE69915478T DE69915478T DE69915478D1 DE 69915478 D1 DE69915478 D1 DE 69915478D1 DE 69915478 T DE69915478 T DE 69915478T DE 69915478 T DE69915478 T DE 69915478T DE 69915478 D1 DE69915478 D1 DE 69915478D1
- Authority
- DE
- Germany
- Prior art keywords
- croscarmellose sodium
- croscarmellose
- preparing
- taste
- bitter
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Lifetime
Links
Classifications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/14—Particulate form, e.g. powders, Processes for size reducing of pure drugs or the resulting products, Pure drug nanoparticles
- A61K9/16—Agglomerates; Granulates; Microbeadlets ; Microspheres; Pellets; Solid products obtained by spray drying, spray freeze drying, spray congealing,(multiple) emulsion solvent evaporation or extraction
- A61K9/1605—Excipients; Inactive ingredients
- A61K9/1629—Organic macromolecular compounds
- A61K9/1652—Polysaccharides, e.g. alginate, cellulose derivatives; Cyclodextrin
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/0012—Galenical forms characterised by the site of application
- A61K9/0053—Mouth and digestive tract, i.e. intraoral and peroral administration
- A61K9/0056—Mouth soluble or dispersible forms; Suckable, eatable, chewable coherent forms; Forms rapidly disintegrating in the mouth; Lozenges; Lollipops; Bite capsules; Baked products; Baits or other oral forms for animals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/48—Preparations in capsules, e.g. of gelatin, of chocolate
- A61K9/50—Microcapsules having a gas, liquid or semi-solid filling; Solid microparticles or pellets surrounded by a distinct coating layer, e.g. coated microspheres, coated drug crystals
- A61K9/5005—Wall or coating material
- A61K9/5021—Organic macromolecular compounds
- A61K9/5036—Polysaccharides, e.g. gums, alginate; Cyclodextrin
- A61K9/5042—Cellulose; Cellulose derivatives, e.g. phthalate or acetate succinate esters of hydroxypropyl methylcellulose
- A61K9/5047—Cellulose ethers containing no ester groups, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2004—Excipients; Inactive ingredients
- A61K9/2022—Organic macromolecular compounds
- A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
- A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K9/00—Medicinal preparations characterised by special physical form
- A61K9/20—Pills, tablets, discs, rods
- A61K9/2072—Pills, tablets, discs, rods characterised by shape, structure or size; Tablets with holes, special break lines or identification marks; Partially coated tablets; Disintegrating flat shaped forms
- A61K9/2077—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets
- A61K9/2081—Tablets comprising drug-containing microparticles in a substantial amount of supporting matrix; Multiparticulate tablets with microcapsules or coated microparticles according to A61K9/50
Landscapes
- Health & Medical Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Veterinary Medicine (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pharmacology & Pharmacy (AREA)
- Epidemiology (AREA)
- Chemical & Material Sciences (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Medicinal Chemistry (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Zoology (AREA)
- Nutrition Science (AREA)
- Physiology (AREA)
- Medicinal Preparation (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Seasonings (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
Applications Claiming Priority (5)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US9199698P | 1998-07-08 | 1998-07-08 | |
US91996P | 1998-07-08 | ||
US09/330,445 US6099865A (en) | 1998-07-08 | 1999-06-11 | Croscarmellose taste masking |
US330445 | 1999-06-11 | ||
PCT/US1999/015510 WO2000002536A1 (en) | 1998-07-08 | 1999-07-08 | Croscarmellose taste masking |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69915478D1 true DE69915478D1 (de) | 2004-04-15 |
DE69915478T2 DE69915478T2 (de) | 2005-01-13 |
Family
ID=26784551
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE1999615478 Expired - Lifetime DE69915478T2 (de) | 1998-07-08 | 1999-07-08 | Geschmacksmaskierung mittels croscarmellose |
Country Status (9)
Country | Link |
---|---|
US (1) | US6099865A (de) |
EP (1) | EP1094788B1 (de) |
AT (1) | ATE261299T1 (de) |
CA (1) | CA2336570C (de) |
DE (1) | DE69915478T2 (de) |
DK (1) | DK1094788T3 (de) |
ES (1) | ES2217774T3 (de) |
PT (1) | PT1094788E (de) |
WO (1) | WO2000002536A1 (de) |
Families Citing this family (32)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US8071128B2 (en) * | 1996-06-14 | 2011-12-06 | Kyowa Hakko Kirin Co., Ltd. | Intrabuccally rapidly disintegrating tablet and a production method of the tablets |
FR2785538B1 (fr) * | 1998-11-06 | 2004-04-09 | Prographarm Laboratoires | Comprime a delitement rapide perfectionne |
US6982251B2 (en) * | 2000-12-20 | 2006-01-03 | Schering Corporation | Substituted 2-azetidinones useful as hypocholesterolemic agents |
CA2461354C (en) * | 2001-09-28 | 2010-04-27 | Mcneil-Ppc, Inc. | Fondant-based pharmaceutical composition |
US9358214B2 (en) | 2001-10-04 | 2016-06-07 | Adare Pharmaceuticals, Inc. | Timed, sustained release systems for propranolol |
US7357891B2 (en) | 2001-10-12 | 2008-04-15 | Monosol Rx, Llc | Process for making an ingestible film |
US20190328679A1 (en) | 2001-10-12 | 2019-10-31 | Aquestive Therapeutics, Inc. | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US8603514B2 (en) | 2002-04-11 | 2013-12-10 | Monosol Rx, Llc | Uniform films for rapid dissolve dosage form incorporating taste-masking compositions |
US10285910B2 (en) | 2001-10-12 | 2019-05-14 | Aquestive Therapeutics, Inc. | Sublingual and buccal film compositions |
US8765167B2 (en) | 2001-10-12 | 2014-07-01 | Monosol Rx, Llc | Uniform films for rapid-dissolve dosage form incorporating anti-tacking compositions |
US20110033542A1 (en) | 2009-08-07 | 2011-02-10 | Monosol Rx, Llc | Sublingual and buccal film compositions |
US11207805B2 (en) | 2001-10-12 | 2021-12-28 | Aquestive Therapeutics, Inc. | Process for manufacturing a resulting pharmaceutical film |
AR040588A1 (es) * | 2002-07-26 | 2005-04-13 | Schering Corp | Formulacion farmaceutica que comprende un inhibidor de la absorcion del colesterol y un inhibidor de una hmg- co a reductasa |
US8367111B2 (en) * | 2002-12-31 | 2013-02-05 | Aptalis Pharmatech, Inc. | Extended release dosage forms of propranolol hydrochloride |
US7208486B2 (en) | 2003-03-07 | 2007-04-24 | Schering Corporation | Substituted azetidinone compounds, processes for preparing the same, formulations and uses thereof |
MXPA05009503A (es) * | 2003-03-07 | 2005-10-18 | Schering Corp | Compuestos de azetidinona sustituidos, formulaciones y usos de los mismos para el tratamiento de hipercolesterolemia. |
EP1673064A1 (de) * | 2003-08-28 | 2006-06-28 | Sandoz AG | Pharmazeutische zusammensetzung mit einem antikonvulsivum mit geschmacksüberdeckendem überzug |
US8747895B2 (en) | 2004-09-13 | 2014-06-10 | Aptalis Pharmatech, Inc. | Orally disintegrating tablets of atomoxetine |
US9884014B2 (en) | 2004-10-12 | 2018-02-06 | Adare Pharmaceuticals, Inc. | Taste-masked pharmaceutical compositions |
NZ728442A (en) * | 2004-10-21 | 2018-05-25 | Adare Pharmaceuticals Inc | Taste-masked pharmaceutical compositions with gastrosoluble pore-formers |
US20060105038A1 (en) * | 2004-11-12 | 2006-05-18 | Eurand Pharmaceuticals Limited | Taste-masked pharmaceutical compositions prepared by coacervation |
US9161918B2 (en) | 2005-05-02 | 2015-10-20 | Adare Pharmaceuticals, Inc. | Timed, pulsatile release systems |
US7842312B2 (en) | 2005-12-29 | 2010-11-30 | Cordis Corporation | Polymeric compositions comprising therapeutic agents in crystalline phases, and methods of forming the same |
WO2011056702A2 (en) * | 2009-10-28 | 2011-05-12 | Mcneil-Ppc, Inc. | Fast dissolving/disintegrating coating compositions |
ES2668203T3 (es) | 2009-12-02 | 2018-05-17 | Adare Pharmaceuticals S.R.L. | Microcápsulas de fexofenadina y composiciones que las contienen |
US20110150993A1 (en) * | 2009-12-22 | 2011-06-23 | Fmc Corporation | Fine Particle Croscarmellose and Uses Thereof |
WO2011085181A1 (en) * | 2010-01-08 | 2011-07-14 | Eurand, Inc. | Taste masked topiramate composition and an orally disintegrating tablet comprising the same |
US9149959B2 (en) | 2010-10-22 | 2015-10-06 | Monosol Rx, Llc | Manufacturing of small film strips |
CN102258490B (zh) * | 2011-07-01 | 2012-10-03 | 中美天津史克制药有限公司 | 布洛芬咀嚼片 |
WO2014184663A2 (en) * | 2013-05-15 | 2014-11-20 | Apr Applied Pharma Research Sa | Orally dispersible drug formulations |
WO2017192921A1 (en) | 2016-05-05 | 2017-11-09 | Monosol Rx, Llc | Enhanced delivery epinephrine compositions |
US11273131B2 (en) | 2016-05-05 | 2022-03-15 | Aquestive Therapeutics, Inc. | Pharmaceutical compositions with enhanced permeation |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JP3130058B2 (ja) * | 1991-02-15 | 2001-01-31 | 第一製薬株式会社 | マスクされた粒状物 |
ATE245023T1 (de) * | 1991-05-28 | 2003-08-15 | Mcneil Ppc Inc | Kaubare zusammensetzung zur arzneimittelfreisetzung |
US5358941A (en) * | 1992-12-02 | 1994-10-25 | Merck & Co., Inc. | Dry mix formulation for bisphosphonic acids with lactose |
CA2184361C (en) * | 1994-03-24 | 2000-12-05 | Francis Bernard Chapura | Solid dose forms containing bismuth |
US5874418A (en) * | 1997-05-05 | 1999-02-23 | Cydex, Inc. | Sulfoalkyl ether cyclodextrin based solid pharmaceutical formulations and their use |
UA65607C2 (uk) * | 1998-03-04 | 2004-04-15 | Орто-Макнейл Фармацевтикал, Інк. | Фармацевтична композиція (варіанти) та спосіб її приготування |
-
1999
- 1999-06-11 US US09/330,445 patent/US6099865A/en not_active Expired - Fee Related
- 1999-07-08 DK DK99932362T patent/DK1094788T3/da active
- 1999-07-08 DE DE1999615478 patent/DE69915478T2/de not_active Expired - Lifetime
- 1999-07-08 ES ES99932362T patent/ES2217774T3/es not_active Expired - Lifetime
- 1999-07-08 EP EP99932362A patent/EP1094788B1/de not_active Expired - Lifetime
- 1999-07-08 PT PT99932362T patent/PT1094788E/pt unknown
- 1999-07-08 CA CA002336570A patent/CA2336570C/en not_active Expired - Fee Related
- 1999-07-08 WO PCT/US1999/015510 patent/WO2000002536A1/en active IP Right Grant
- 1999-07-08 AT AT99932362T patent/ATE261299T1/de not_active IP Right Cessation
Also Published As
Publication number | Publication date |
---|---|
CA2336570A1 (en) | 2000-01-20 |
WO2000002536A1 (en) | 2000-01-20 |
ES2217774T3 (es) | 2004-11-01 |
PT1094788E (pt) | 2004-07-30 |
ATE261299T1 (de) | 2004-03-15 |
EP1094788A4 (de) | 2003-04-02 |
DK1094788T3 (da) | 2004-08-16 |
EP1094788B1 (de) | 2004-03-10 |
DE69915478T2 (de) | 2005-01-13 |
CA2336570C (en) | 2009-04-14 |
EP1094788A1 (de) | 2001-05-02 |
US6099865A (en) | 2000-08-08 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition |