DE69911300D1 - Niedrigsubstituierte Hydroxypropylcellulose und Verfahren zu deren Herstellung - Google Patents

Niedrigsubstituierte Hydroxypropylcellulose und Verfahren zu deren Herstellung

Info

Publication number
DE69911300D1
DE69911300D1 DE69911300T DE69911300T DE69911300D1 DE 69911300 D1 DE69911300 D1 DE 69911300D1 DE 69911300 T DE69911300 T DE 69911300T DE 69911300 T DE69911300 T DE 69911300T DE 69911300 D1 DE69911300 D1 DE 69911300D1
Authority
DE
Germany
Prior art keywords
manufacture
hydroxypropyl cellulose
substituted hydroxypropyl
low substituted
low
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69911300T
Other languages
English (en)
Other versions
DE69911300T2 (de
Inventor
Sakae Obara
Hiroshi Umezawa
Naosuke Maruyama
Fumie Tanno
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Shin Etsu Chemical Co Ltd
Original Assignee
Shin Etsu Chemical Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Shin Etsu Chemical Co Ltd filed Critical Shin Etsu Chemical Co Ltd
Publication of DE69911300D1 publication Critical patent/DE69911300D1/de
Application granted granted Critical
Publication of DE69911300T2 publication Critical patent/DE69911300T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/20—Pills, tablets, discs, rods
    • A61K9/2004—Excipients; Inactive ingredients
    • A61K9/2022—Organic macromolecular compounds
    • A61K9/205—Polysaccharides, e.g. alginate, gums; Cyclodextrin
    • A61K9/2054—Cellulose; Cellulose derivatives, e.g. hydroxypropyl methylcellulose
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B15/00—Preparation of other cellulose derivatives or modified cellulose, e.g. complexes
    • C08B15/02—Oxycellulose; Hydrocellulose; Cellulosehydrate, e.g. microcrystalline cellulose
    • C—CHEMISTRY; METALLURGY
    • C08—ORGANIC MACROMOLECULAR COMPOUNDS; THEIR PREPARATION OR CHEMICAL WORKING-UP; COMPOSITIONS BASED THEREON
    • C08B—POLYSACCHARIDES; DERIVATIVES THEREOF
    • C08B11/00—Preparation of cellulose ethers
    • C08B11/02—Alkyl or cycloalkyl ethers
    • C08B11/04—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals
    • C08B11/08—Alkyl or cycloalkyl ethers with substituted hydrocarbon radicals with hydroxylated hydrocarbon radicals; Esters, ethers, or acetals thereof

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Polymers & Plastics (AREA)
  • Materials Engineering (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Organic Chemistry (AREA)
  • Epidemiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Polysaccharides And Polysaccharide Derivatives (AREA)
  • Medicinal Preparation (AREA)
  • Processes Of Treating Macromolecular Substances (AREA)
DE69911300T 1998-05-12 1999-05-12 Niedrigsubstituierte Hydroxypropylcellulose und Verfahren zu deren Herstellung Expired - Lifetime DE69911300T2 (de)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP12835798A JP3718341B2 (ja) 1998-05-12 1998-05-12 低置換度ヒドロキシプロピルセルロースとその製造方法
JP12835798 1998-05-12

Publications (2)

Publication Number Publication Date
DE69911300D1 true DE69911300D1 (de) 2003-10-23
DE69911300T2 DE69911300T2 (de) 2004-07-15

Family

ID=14982830

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69911300T Expired - Lifetime DE69911300T2 (de) 1998-05-12 1999-05-12 Niedrigsubstituierte Hydroxypropylcellulose und Verfahren zu deren Herstellung

Country Status (7)

Country Link
US (2) US6525192B2 (de)
EP (1) EP0957112B1 (de)
JP (1) JP3718341B2 (de)
KR (1) KR100473313B1 (de)
DE (1) DE69911300T2 (de)
ES (1) ES2207058T3 (de)
TW (1) TWI230617B (de)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2581111A1 (en) * 1998-07-28 2000-02-10 Takeda Pharmaceutical Company Limited Rapidly disintegrable solid preparation
JP4044689B2 (ja) * 1998-12-07 2008-02-06 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロースの製造方法
JP3572213B2 (ja) * 1999-01-18 2004-09-29 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース
EP1133984B1 (de) * 2000-03-17 2005-05-11 Shin-Etsu Chemical Co., Ltd. Feste Zubereitung enthaltend niedersubstituierte Hydroxypropylcellulose und Herstellungsverfahren
JP3595765B2 (ja) * 2000-09-27 2004-12-02 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロースを含む乾式直打用基剤
US6933381B2 (en) * 2001-02-02 2005-08-23 Charles B. Mallon Method of preparing modified cellulose ether
DE60221342T2 (de) 2001-12-11 2008-04-10 Shin-Etsu Chemical Co., Ltd. Niedrig substituierte Hydroxypropylzellulose
JP2003252749A (ja) * 2002-03-04 2003-09-10 Shin Etsu Chem Co Ltd 外用基剤
JP2004033142A (ja) * 2002-07-05 2004-02-05 Showa Sangyo Co Ltd 顆粒状天ぷら粉
JP2004216610A (ja) * 2003-01-10 2004-08-05 Shin Etsu Chem Co Ltd 紙／フィルム複合構造体及びその製造方法
JP2007308479A (ja) 2006-04-20 2007-11-29 Shin Etsu Chem Co Ltd 固体分散体製剤
JP2007308480A (ja) * 2006-04-20 2007-11-29 Shin Etsu Chem Co Ltd 腸溶性固体分散体を含んでなる固形製剤
US8343548B2 (en) 2006-08-08 2013-01-01 Shin-Etsu Chemical Co., Ltd. Solid dosage form comprising solid dispersion
US8343547B2 (en) * 2006-08-08 2013-01-01 Shin-Etsu Chemical Co., Ltd. Solid dosage form comprising solid dispersion
JP5089287B2 (ja) * 2006-08-08 2012-12-05 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース粉末の製造方法
US8519120B2 (en) 2006-08-08 2013-08-27 Shin-Etsu Chemical Co., Ltd. Methods for producing a low-substituted hydroxypropylcellulose powder
JP5258224B2 (ja) * 2006-08-08 2013-08-07 信越化学工業株式会社 固体分散体の固形製剤及びその製造方法
JP5031054B2 (ja) * 2010-03-18 2012-09-19 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース及びこれを含む固形製剤
EP2428523B1 (de) * 2010-09-14 2017-12-06 Shin-Etsu Chemical Co., Ltd. Verfahren zur Herstellung von niedrigsubstituierter Hydroxypropylcellulose
JP6238831B2 (ja) * 2014-04-25 2017-11-29 沢井製薬株式会社 バルサルタン含有錠剤及びその製造方法
JP7234076B2 (ja) * 2019-08-27 2023-03-07 信越化学工業株式会社 篩分け低置換度ヒドロキシプロピルセルロースの製造方法

Family Cites Families (20)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2488631A (en) 1945-05-19 1949-11-22 American Viscose Corp Cellulose ethers and the process for producing the same
NL99185C (de) 1959-07-30
US3251824A (en) 1961-08-22 1966-05-17 Fmc Corp Method of preparing stable aqueous dispersion-forming cellulosic aggregates
US3852421A (en) 1970-03-23 1974-12-03 Shinetsu Chemical Co Excipient and shaped medicaments prepared therewith
JPS5119017B2 (de) 1972-04-12 1976-06-14
JPS5163927A (en) * 1974-11-28 1976-06-02 Shinetsu Chemical Co Ketsugoseiryokonajozaihokaizaino seizohoho
AU508480B2 (en) * 1977-04-13 1980-03-20 Asahi Kasei Kogyo Kabushiki Kaisha Microcrystalline cellulose excipient and pharmaceutical composition containing thesame
DE3038001A1 (de) 1980-10-08 1982-05-06 Henkel KGaA, 4000 Düsseldorf Verfahren zur herstellung von mikropulvern aus celluloseether oder cellulose
US4329451A (en) 1980-11-03 1982-05-11 The Dow Chemical Company Preparing an aqueous dispersion of colloidal size particles of a water-insoluble polysaccharide derivative
JPS5839618A (ja) 1981-09-04 1983-03-08 Chugai Pharmaceut Co Ltd 持続性積層錠剤
US4716186A (en) 1986-04-09 1987-12-29 A. E. Staley Manufacturing Company Starch derivatives and methods of making using same
US5026560A (en) 1987-01-29 1991-06-25 Takeda Chemical Industries, Ltd. Spherical granules having core and their production
DD263996A1 (de) * 1987-08-26 1989-01-18 Finowtal Chem Fab Verfahren zur kontinuierlichen herstellung von alkalicellulose
US5200194A (en) 1991-12-18 1993-04-06 Alza Corporation Oral osmotic device
GB2262527A (en) 1992-07-02 1993-06-23 Dow Deutschland Inc Process for grinding cellulose compounds
JP2994956B2 (ja) * 1994-05-31 1999-12-27 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース、その組成物およびその錠剤
BE1009856A5 (fr) 1995-07-14 1997-10-07 Sandoz Sa Composition pharmaceutique sous la forme d'une dispersion solide comprenant un macrolide et un vehicule.
JP3212532B2 (ja) 1997-03-26 2001-09-25 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロースの製造方法
TW592727B (en) 1997-04-04 2004-06-21 Chugai Pharmaceutical Co Ltd Phosphate-binding polymer preparations
JP3212534B2 (ja) 1997-04-08 2001-09-25 信越化学工業株式会社 低置換度ヒドロキシプロピルセルロース粉末

Also Published As

Publication number Publication date
JP3718341B2 (ja) 2005-11-24
EP0957112A3 (de) 2000-04-26
US6525192B2 (en) 2003-02-25
JPH11322802A (ja) 1999-11-26
KR19990088166A (ko) 1999-12-27
TWI230617B (en) 2005-04-11
US20030125543A1 (en) 2003-07-03
EP0957112B1 (de) 2003-09-17
ES2207058T3 (es) 2004-05-16
US20020016452A1 (en) 2002-02-07
EP0957112A2 (de) 1999-11-17
KR100473313B1 (ko) 2005-03-07
DE69911300T2 (de) 2004-07-15

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