DE69841481D1 - Verabreichung von arginin zur erwärmung von kaltem/kühlem gewebe - Google Patents

Verabreichung von arginin zur erwärmung von kaltem/kühlem gewebe

Info

Publication number
DE69841481D1
DE69841481D1 DE69841481T DE69841481T DE69841481D1 DE 69841481 D1 DE69841481 D1 DE 69841481D1 DE 69841481 T DE69841481 T DE 69841481T DE 69841481 T DE69841481 T DE 69841481T DE 69841481 D1 DE69841481 D1 DE 69841481D1
Authority
DE
Germany
Prior art keywords
arginine
cold
administration
heating
tissue
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69841481T
Other languages
English (en)
Inventor
Eric Fossel
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Strategic Science and Technologies LLC
Original Assignee
Strategic Science and Technologies LLC
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US08/932,595 external-priority patent/US5922332A/en
Priority claimed from US08/936,188 external-priority patent/US5895658A/en
Priority claimed from US08/932,227 external-priority patent/US7914814B2/en
Priority claimed from US08/936,189 external-priority patent/US6207713B1/en
Application filed by Strategic Science and Technologies LLC filed Critical Strategic Science and Technologies LLC
Application granted granted Critical
Publication of DE69841481D1 publication Critical patent/DE69841481D1/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/0208Tissues; Wipes; Patches
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00Medicinal preparations containing organic active ingredients
    • A61K31/185Acids; Anhydrides, halides or salts thereof, e.g. sulfur acids, imidic, hydrazonic or hydroximic acids
    • A61K31/19Carboxylic acids, e.g. valproic acid
    • A61K31/195Carboxylic acids, e.g. valproic acid having an amino group
    • A61K31/197Carboxylic acids, e.g. valproic acid having an amino group the amino and the carboxyl groups being attached to the same acyclic carbon chain, e.g. gamma-aminobutyric acid [GABA], beta-alanine, epsilon-aminocaproic acid, pantothenic acid
    • A61K31/198Alpha-aminoacids, e.g. alanine, edetic acids [EDTA]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/02Cosmetics or similar toiletry preparations characterised by special physical form
    • A61K8/14Liposomes; Vesicles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K8/00Cosmetics or similar toiletry preparations
    • A61K8/18Cosmetics or similar toiletry preparations characterised by the composition
    • A61K8/30Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds
    • A61K8/40Cosmetics or similar toiletry preparations characterised by the composition containing organic compounds containing nitrogen
    • A61K8/44Aminocarboxylic acids or derivatives thereof, e.g. aminocarboxylic acids containing sulfur; Salts; Esters or N-acylated derivatives thereof
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00Drugs for genital or sexual disorders; Contraceptives
    • A61P15/10Drugs for genital or sexual disorders; Contraceptives for impotence
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/02Drugs for dermatological disorders for treating wounds, ulcers, burns, scars, keloids, or the like
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • A61P17/14Drugs for dermatological disorders for baldness or alopecia
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • A61P23/02Local anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00Drugs for disorders of the nervous system
    • A61P25/04Centrally acting analgesics, e.g. opioids
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/10Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q19/00Preparations for care of the skin
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61QSPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS
    • A61Q7/00Preparations for affecting hair growth
DE69841481T 1997-09-17 1998-09-17 Verabreichung von arginin zur erwärmung von kaltem/kühlem gewebe Expired - Lifetime DE69841481D1 (de)

Applications Claiming Priority (5)

Application Number Priority Date Filing Date Title
US08/932,595 US5922332A (en) 1997-09-17 1997-09-17 Topical delivery of arginine to overcome pain
US08/936,188 US5895658A (en) 1997-09-17 1997-09-17 Topical delivery of L-arginine to cause tissue warming
US08/932,227 US7914814B2 (en) 1997-09-17 1997-09-17 Topical delivery of arginine of cause beneficial effects
US08/936,189 US6207713B1 (en) 1997-09-17 1997-09-17 Topical and oral delivery of arginine to cause beneficial effects
PCT/US1998/019429 WO1999013717A1 (en) 1997-09-17 1998-09-17 A delivery of arginine to cause beneficial effects

Publications (1)

Publication Number Publication Date
DE69841481D1 true DE69841481D1 (de) 2010-03-18

Family

ID=27506014

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69841481T Expired - Lifetime DE69841481D1 (de) 1997-09-17 1998-09-17 Verabreichung von arginin zur erwärmung von kaltem/kühlem gewebe

Country Status (8)

Country Link
EP (2) EP2158907B1 (de)
JP (3) JP4352114B2 (de)
AT (1) ATE456302T1 (de)
AU (1) AU737199B2 (de)
CA (1) CA2303394C (de)
DE (1) DE69841481D1 (de)
ES (2) ES2340450T3 (de)
WO (1) WO1999013717A1 (de)

Families Citing this family (40)

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US7629384B2 (en) 1997-09-17 2009-12-08 Strategic Science & Technologies, Llc Topical delivery of L-arginine to cause beneficial effects
US7914814B2 (en) 1997-09-17 2011-03-29 Strategic Science & Technologies, Llc Topical delivery of arginine of cause beneficial effects
US6284797B1 (en) * 1999-04-12 2001-09-04 Donald A. Rhodes Topical treatment of pain and to promote healing
JP2000327560A (ja) * 1999-05-18 2000-11-28 Noevir Co Ltd 入浴剤組成物
FR2794974B1 (fr) * 1999-06-16 2001-08-17 Exsymol Sa Composition cosmetique pour l'amincissement a base de l-arginine, d'un analogue de l-arginine ou d'un de leurs derives, applicable par voie topique
US6322493B1 (en) * 1999-07-01 2001-11-27 40 J's Llc Expanded clitoral sensitizing compounds with methods and apparatus for the delivery of these compounds
JP4681132B2 (ja) * 2001-01-29 2011-05-11 味の素株式会社 一酸化窒素合成酵素産生促進剤および化粧料若しくは医薬組成物
DE10113446A1 (de) * 2001-03-19 2002-09-26 Schwarzkopf Gmbh Hans Haarbehandlungsmittel mit Betainen
WO2003072039A2 (en) * 2002-02-22 2003-09-04 Essentia Biosystems, Inc. Cosmetic formulations containing l-arginine oligomers
US7326717B2 (en) 2003-05-06 2008-02-05 L'oreal Pyrimidine n-oxide compounds for stimulating the growth of keratin fibers and/or reducing loss thereof
EP1732577B1 (de) * 2004-02-23 2013-04-10 Strategic Science & Technologies, LLC Topische verabreichung von l-arginin zur verbesserung des aussehens von körper und haut
JP2005281272A (ja) * 2004-03-31 2005-10-13 Suntory Ltd 末梢血流改善剤
JP4837896B2 (ja) * 2004-03-31 2011-12-14 焼津水産化学工業株式会社 精力増強剤
JP4836044B2 (ja) * 2004-04-02 2011-12-14 味の素株式会社 経口アミノ酸ニキビ治療剤
EP2417978A1 (de) 2004-04-19 2012-02-15 Strategic Science & Technologies, LLC Vorteilhafte Wirkungen der Verstärkung des lokalen Blutflusses
AU2012201048B2 (en) * 2004-04-19 2013-06-06 Strategic Science & Technologies, Llc Transdermal delivery of beneficial substances effected by a hostile biophysical environment
US9226909B2 (en) 2004-04-19 2016-01-05 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
CA2563678A1 (en) * 2004-04-19 2005-11-03 Strategic Science & Technologies, Llc Beneficial effects of increasing local blood flow
JP2006169406A (ja) * 2004-12-16 2006-06-29 Fuji Latex Kk コンドーム用水性潤滑剤および当該潤滑剤を塗布したコンドーム
JP2008179540A (ja) * 2005-01-07 2008-08-07 Noevir Co Ltd 細胞分化、発生、増殖を制御する物質および該物質を含む細胞分化・発生・増殖調節剤
WO2006097359A1 (en) * 2005-03-18 2006-09-21 L'oréal Hair and/or eyelash care composition containing aminexil in combination with an agent for promoting the no production and uses thereof
FR2883167B1 (fr) * 2005-03-18 2009-07-10 Oreal Composition de soin capillaire et/ou des cils contenant de l'aminexil en association avec un vasodilatateur, destinee a stimuler la croissance des cheveux et/ou des cils et/ou freiner leur chute, ses utilisations
JP5046174B2 (ja) * 2005-03-31 2012-10-10 味の素株式会社 アルギニン含有血流増加用組成物
US8445536B2 (en) 2005-03-31 2013-05-21 Ajinomoto Co., Inc. Arginine-containing compositions and methods for increasing blood flow using same
WO2007079394A2 (en) 2005-12-30 2007-07-12 Revance Therapeutics, Inc. Arginine heteromers for topical administration
WO2008089435A1 (en) * 2007-01-18 2008-07-24 Wyeth Methods of identifying pain modulators
WO2009036771A1 (es) * 2007-09-21 2009-03-26 Pharmabrand S.A. Composición de polisacáridos mucilaginosos, derivados de aloe barbadensis, en combinación con liposomas, procedimiento de obtención y uso de la misma como fotoprotectora, antiacné, regeneradora de la epidermis e hidratante
FR2929118B1 (fr) * 2008-03-28 2010-05-07 Oreal Utilisation de l'association de madecassoside et/ou de terminoloside et d'une arginine pour induire et/ou stimuler la croissance de ces fibres keratiniques humaines et/ou freiner leur chute
AU2015203547B2 (en) * 2009-06-24 2017-05-18 Strategic Science & Technologies, Llc Topical composition containing ibuprofen
EP2445492B1 (de) * 2009-06-24 2016-09-28 Strategic Science & Technologies, LLC Topische zusammensetzung mit ibuprofen
US11684624B2 (en) 2009-06-24 2023-06-27 Strategic Science & Technologies, Llc Treatment of erectile dysfunction and other indications
EP2445493A1 (de) * 2009-06-24 2012-05-02 Strategic Science & Technologies, LLC Topische zusammensetzung mit naproxen
EP2658551B1 (de) 2010-12-29 2020-07-01 Strategic Science & Technologies, LLC Behandlung von erektionsstörungen und anderen indikationen
CN105878172A (zh) 2010-12-29 2016-08-24 战略科学与技术有限责任公司 治疗变态反应和其它适应症的系统和方法
EP2968130A1 (de) 2013-03-15 2016-01-20 Strategic Science & Technologies, LLC Transdermale verabreichung von sildenafil und anderen phosphodiesterase-typ-5-inhibitoren
US20160081915A1 (en) 2013-03-15 2016-03-24 Strategic Science & Technologies, Llc Transdermal formulations of fluticasone
WO2016094316A1 (en) * 2014-12-08 2016-06-16 Synaptamine, Inc. Anti-rds compounds and method of manufacture and administration thereof to induce dopamine homeostatis
WO2016112201A1 (en) 2015-01-07 2016-07-14 Strategic Science & Technologies, Llc Techniques and systems for transdermal delivery involving treatment of psoriasis, skin cancer, and other indications
MY176129A (en) * 2015-08-06 2020-07-24 Coats Agri Aloe Llc Compositions and methods to increase plant yield
GB201620701D0 (en) * 2016-12-06 2017-01-18 Glaxosmithkline Consumer Healthcare (Uk) Ip Ltd Novel composition

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FR2602678B1 (fr) * 1986-08-13 1992-06-05 Drouault Guy Composition pharmaceutique aqueuse a base de sels de magnesium, sodium et potassium pour la regulation des circulations locales
PT95564B (pt) * 1989-10-17 1997-11-28 Merck & Co Inc Processo para a preparacao de (+)-ibuprofen-d-aminoacido uteis como analgesicos intensificados de ataque acelerado
JPH045231A (ja) * 1990-04-20 1992-01-09 Morishita Pharmaceut Co Ltd 慢性痛用鎮痛剤
JPH0789862A (ja) * 1990-05-29 1995-04-04 Toyobo Co Ltd 抗炎症性、免疫抑制性および鎮痛性組成物、およびこれらの組成物を用いた自己免疫疾患の治療方法
DE4100975A1 (de) * 1991-01-15 1992-07-16 Weuffen Wolfgang Kosmetische oder pharmazeutische zubereitungen zur verbesserung der haarqualitaet und foerderung des haarwachstums
US5852058A (en) * 1993-06-11 1998-12-22 The Board Of Trustees Of The Leland Stanford Junior University Intramural delivery of nitric oxide enhancer for inhibiting lesion formation after vascular injury
DE4338793A1 (de) * 1993-11-12 1995-05-18 Froelich Juergen C L-Arginin und Analoge als Thrombozytenaggregationshemmer
DE4341000A1 (de) * 1993-12-02 1995-06-08 Beiersdorf Ag Verwendung von L-Arginin, L-Ornithin oder L-Citrullin und topischen Zubereitungen mit diesen Stoffen
US5594032A (en) * 1994-11-10 1997-01-14 Gonzalez-Cadavid; Nestor F. Amelioration of human erectile dysfunction by treatment with iNOS, inducers of iNOS or iNOS cDNA
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Also Published As

Publication number Publication date
WO1999013717B1 (en) 1999-04-22
EP1041880B1 (de) 2010-01-27
JP2009143968A (ja) 2009-07-02
AU9318698A (en) 1999-04-05
EP2158907A3 (de) 2010-05-26
JP4352114B2 (ja) 2009-10-28
EP1041880A4 (de) 2006-04-12
ATE456302T1 (de) 2010-02-15
JP2002515401A (ja) 2002-05-28
ES2340450T3 (es) 2010-06-02
EP2158907A2 (de) 2010-03-03
EP2158907B1 (de) 2015-08-05
JP2015038119A (ja) 2015-02-26
WO1999013717A1 (en) 1999-03-25
EP1041880A1 (de) 2000-10-11
AU737199B2 (en) 2001-08-09
ES2549329T3 (es) 2015-10-27
CA2303394C (en) 2011-12-20
CA2303394A1 (en) 1999-03-25

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