DE69838298T2 - Kontrolle der immunantworten durch regulierung der aktivität von glykosyltransferasen - Google Patents
Kontrolle der immunantworten durch regulierung der aktivität von glykosyltransferasen Download PDFInfo
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- DE69838298T2 DE69838298T2 DE69838298T DE69838298T DE69838298T2 DE 69838298 T2 DE69838298 T2 DE 69838298T2 DE 69838298 T DE69838298 T DE 69838298T DE 69838298 T DE69838298 T DE 69838298T DE 69838298 T2 DE69838298 T2 DE 69838298T2
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- sialyltransferase
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- C12N15/00—Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
- C12N15/09—Recombinant DNA-technology
- C12N15/11—DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
- C12N15/113—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing
- C12N15/1137—Non-coding nucleic acids modulating the expression of genes, e.g. antisense oligonucleotides; Antisense DNA or RNA; Triplex- forming oligonucleotides; Catalytic nucleic acids, e.g. ribozymes; Nucleic acids used in co-suppression or gene silencing against enzymes
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- A01K67/00—Rearing or breeding animals, not otherwise provided for; New or modified breeds of animals
- A01K67/027—New or modified breeds of vertebrates
- A01K67/0271—Chimeric vertebrates, e.g. comprising exogenous cells
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- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P37/00—Drugs for immunological or allergic disorders
- A61P37/02—Immunomodulators
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- C—CHEMISTRY; METALLURGY
- C12—BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
- C12N—MICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
- C12N9/00—Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
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- A—HUMAN NECESSITIES
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- A01K—ANIMAL HUSBANDRY; AVICULTURE; APICULTURE; PISCICULTURE; FISHING; REARING OR BREEDING ANIMALS, NOT OTHERWISE PROVIDED FOR; NEW BREEDS OF ANIMALS
- A01K2217/00—Genetically modified animals
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- A01K2217/075—Animals genetically altered by homologous recombination inducing loss of function, i.e. knock out
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| US5453272A (en) | 1992-10-02 | 1995-09-26 | Alberta Research Council | Lectin derived carbohydrate binding-peptide |
| AU2828595A (en) | 1994-06-15 | 1996-01-05 | Alexion Pharmaceuticals, Inc. | Methods for reducing hyperacute rejection of xenografts |
| AU2001296705A1 (en) * | 2000-10-06 | 2002-04-15 | The Regents Of The University Of California | Blocking inflammation by inhibiting sialylation |
-
1996
- 1996-12-27 JP JP52994198A patent/JP4451933B2/ja not_active Expired - Fee Related
-
1998
- 1998-05-29 DE DE69838298T patent/DE69838298T2/de not_active Expired - Lifetime
- 1998-05-29 AU AU77175/98A patent/AU7717598A/en not_active Abandoned
- 1998-05-29 EP EP98925161A patent/EP1017846B1/en not_active Expired - Lifetime
- 1998-05-29 AT AT98925161T patent/ATE371041T1/de not_active IP Right Cessation
- 1998-05-29 WO PCT/US1998/011260 patent/WO1998054365A1/en not_active Ceased
- 1998-05-29 US US09/087,117 patent/US6376475B1/en not_active Expired - Lifetime
- 1998-05-29 JP JP50102499A patent/JP2002528037A/ja not_active Ceased
-
2002
- 2002-04-23 US US10/131,721 patent/US20030013636A1/en not_active Abandoned
Also Published As
| Publication number | Publication date |
|---|---|
| EP1017846A1 (en) | 2000-07-12 |
| DE69838298D1 (de) | 2007-10-04 |
| EP1017846A4 (en) | 2004-08-11 |
| ATE371041T1 (de) | 2007-09-15 |
| WO1998054365A1 (en) | 1998-12-03 |
| US20030013636A1 (en) | 2003-01-16 |
| AU7717598A (en) | 1998-12-30 |
| JP4451933B2 (ja) | 2010-04-14 |
| EP1017846B1 (en) | 2007-08-22 |
| US6376475B1 (en) | 2002-04-23 |
| JP2002528036A (ja) | 2002-08-27 |
| JP2002528037A (ja) | 2002-08-27 |
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