DE69836638D1 - Peptidanaloga abgeleitet vom tumornekrose-faktor-rezeptor - Google Patents

Peptidanaloga abgeleitet vom tumornekrose-faktor-rezeptor

Info

Publication number
DE69836638D1
DE69836638D1 DE69836638T DE69836638T DE69836638D1 DE 69836638 D1 DE69836638 D1 DE 69836638D1 DE 69836638 T DE69836638 T DE 69836638T DE 69836638 T DE69836638 T DE 69836638T DE 69836638 D1 DE69836638 D1 DE 69836638D1
Authority
DE
Germany
Prior art keywords
factor receptor
tnf
peptide analogue
analogue derived
necrose factor
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
DE69836638T
Other languages
English (en)
Other versions
DE69836638T2 (de
Inventor
Mark I Greene
Ramachandran Murali
Wataru Takasaki
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
University of Pennsylvania Penn
Original Assignee
University of Pennsylvania Penn
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by University of Pennsylvania Penn filed Critical University of Pennsylvania Penn
Application granted granted Critical
Publication of DE69836638D1 publication Critical patent/DE69836638D1/de
Publication of DE69836638T2 publication Critical patent/DE69836638T2/de
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/705—Receptors; Cell surface antigens; Cell surface determinants
    • C07K14/70578—NGF-receptor/TNF-receptor superfamily, e.g. CD27, CD30, CD40, CD95
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02A—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE
    • Y02A50/00—TECHNOLOGIES FOR ADAPTATION TO CLIMATE CHANGE in human health protection, e.g. against extreme weather
    • Y02A50/30—Against vector-borne diseases, e.g. mosquito-borne, fly-borne, tick-borne or waterborne diseases whose impact is exacerbated by climate change

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Immunology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Cell Biology (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
DE69836638T 1997-05-30 1998-05-29 Peptidanaloga abgeleitet vom tumornekrose-faktor-rezeptor Expired - Lifetime DE69836638T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US866545 1997-05-30
US08/866,545 US6265535B1 (en) 1997-05-30 1997-05-30 Peptides and peptide analogues designed from binding sites of tumor necrosis factor receptor superfamily and their uses
PCT/US1998/010891 WO1998053842A1 (en) 1997-05-30 1998-05-29 Tumor necrosis factor receptor-derived peptide analogues

Publications (2)

Publication Number Publication Date
DE69836638D1 true DE69836638D1 (de) 2007-01-25
DE69836638T2 DE69836638T2 (de) 2007-10-04

Family

ID=25347839

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69836638T Expired - Lifetime DE69836638T2 (de) 1997-05-30 1998-05-29 Peptidanaloga abgeleitet vom tumornekrose-faktor-rezeptor

Country Status (10)

Country Link
US (1) US6265535B1 (de)
EP (2) EP1837344A1 (de)
AT (1) ATE348106T1 (de)
AU (4) AU744925B2 (de)
CA (1) CA2291963C (de)
DE (1) DE69836638T2 (de)
DK (1) DK1011704T3 (de)
ES (1) ES2279575T3 (de)
PT (1) PT1011704E (de)
WO (1) WO1998053842A1 (de)

Families Citing this family (31)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2000021981A2 (de) * 1998-10-09 2000-04-20 Bioserv Ag TNFα BINDENDE PEPTIDE UND IHRE ANWENDUNG FÜR DIE DETEKTION, INAKTIVIERUNG UND/ODER ENTFERNUNG VON TNFα AUS BIOLOGISCHEN FLÜSSIGKEITEN
US6660843B1 (en) 1998-10-23 2003-12-09 Amgen Inc. Modified peptides as therapeutic agents
MEP42108A (en) 1998-10-23 2011-02-10 Kiren Amgen Inc Dimeric thrombopoietin peptide mimetics binding to mp1 receptor and having thrombopoietic activity
US7488590B2 (en) 1998-10-23 2009-02-10 Amgen Inc. Modified peptides as therapeutic agents
IL130989A0 (en) * 1999-07-20 2001-01-28 Compugen Ltd Variants of alternative splicing
US6673771B1 (en) 1999-07-28 2004-01-06 The Trustees Of The University Of Pennsylvania Methods of inhibiting osteoclast activity
JP2003505514A (ja) * 1999-07-28 2003-02-12 ザ トラスティーズ オブ ザ ユニバーシティ オブ ペンシルベニア 破骨細胞生成を阻害する方法
US6682739B1 (en) * 1999-07-28 2004-01-27 The Trustees Of The University Of Pennsylvania Methods of inhibiting osteoclastogenesis
US6808902B1 (en) 1999-11-12 2004-10-26 Amgen Inc. Process for correction of a disulfide misfold in IL-1Ra Fc fusion molecules
CA2774959C (en) 2000-08-04 2016-05-31 Dmi Biosciences, Inc. Method of using diketopiperazines and composition containing them
CA2451955C (en) 2001-06-26 2015-09-29 Abgenix, Inc. Antibodies to opgl
JP4405916B2 (ja) * 2002-05-23 2010-01-27 トラスティース・オブ・ザ・ユニバーシティ・オブ・ペンシルバニア Ｆａｓペプチド模倣体およびその使用
AU2003280130B2 (en) 2002-06-28 2009-06-11 Centocor, Inc. Mammalian CH1 deleted mimetibodies, compositions, methods and uses
CA2500652A1 (en) * 2002-10-02 2004-04-15 Dmi Biosciences, Inc. Diagnosis and monitoring of diseases
JP2007500747A (ja) 2003-05-15 2007-01-18 ディーエムアイ バイオサイエンシズ インコーポレイテッド Ｔ細胞媒介性疾患の処置
US7304115B2 (en) * 2003-12-30 2007-12-04 3M Innovative Properties Company Fluoropolymer coagulation method and composition
EP1773400A2 (de) 2004-07-08 2007-04-18 Amgen Inc. Therapeutische peptide
US8008453B2 (en) 2005-08-12 2011-08-30 Amgen Inc. Modified Fc molecules
US9283260B2 (en) 2006-04-21 2016-03-15 Amgen Inc. Lyophilized therapeutic peptibody formulations
JP5856843B2 (ja) * 2008-05-27 2016-02-10 アンピオ ファーマシューティカルズ，インコーポレイテッド ジケトピペラジンを用いた医薬組成物
CA2782320A1 (en) * 2009-12-02 2011-06-09 Acceleron Pharma Inc. Compositions and methods for increasing serum half-life of fc fusion proteins
CA2810844C (en) 2010-09-07 2017-03-21 Dmi Acquisition Corp. Diketopiperazine compositions for the treatment of metabolic syndrome and related conditions
EP2684888B1 (de) 2011-03-09 2019-05-15 Jitsubo Co., Ltd. Neue vernetztes peptide mit einer nichtpeptidischen vernetzten struktur, verfahren zur synthetisierung vernetzter peptide und in dem verfahren verwendete neuartige organische verbindung
US8883982B2 (en) 2011-06-08 2014-11-11 Acceleron Pharma, Inc. Compositions and methods for increasing serum half-life
SG10201608087WA (en) 2011-10-10 2016-11-29 Ampio Pharmaceuticals Inc Implantable medical devices with increased immune tolerance, and methods for making and implanting
EP2766029B1 (de) 2011-10-10 2020-03-25 Ampio Pharmaceuticals, Inc. Behandlung degenerativer gelenkerkrankungen
MX355446B (es) 2011-10-28 2018-04-18 Ampio Pharmaceuticals Inc Tratamiento de rinitis.
CA2906864A1 (en) 2013-03-15 2014-09-18 Ampio Pharmaceuticals, Inc. Compositions for the mobilization, homing, expansion and differentiation of stem cells and methods of using the same
US9365615B2 (en) 2013-09-09 2016-06-14 Jitsubo Co., Ltd. Cross-linked peptides containing non-peptide cross-linked structure, method for synthesizing cross-linked peptides, and novel organic compound used in method
KR20170045274A (ko) 2014-08-18 2017-04-26 앰피오 파마슈티컬스 인코퍼레이티드 관절 징후의 치료
US11389512B2 (en) 2015-06-22 2022-07-19 Ampio Pharmaceuticals, Inc. Use of low molecular weight fractions of human serum albumin in treating diseases

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO812612L (no) 1980-08-06 1982-02-08 Ferring Pharma Ltd Enzym-inhibitorer.
GB9402331D0 (en) * 1994-02-07 1994-03-30 Univ Mcgill Nerve growth factor structural analogs and their uses

Also Published As

Publication number Publication date
AU778124B2 (en) 2004-11-18
EP1011704B1 (de) 2006-12-13
AU7603698A (en) 1998-12-30
EP1011704A4 (de) 2002-07-31
CA2291963C (en) 2011-04-19
DK1011704T3 (da) 2007-04-23
EP1011704A1 (de) 2000-06-28
AU4584402A (en) 2002-07-25
AU2008243270B2 (en) 2011-09-01
AU2005200634A1 (en) 2005-03-17
PT1011704E (pt) 2007-03-30
ES2279575T3 (es) 2007-08-16
AU2008243270A1 (en) 2008-12-11
AU744925B2 (en) 2002-03-07
DE69836638T2 (de) 2007-10-04
EP1837344A1 (de) 2007-09-26
WO1998053842A1 (en) 1998-12-03
ATE348106T1 (de) 2007-01-15
CA2291963A1 (en) 1998-12-03
US6265535B1 (en) 2001-07-24

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