DE69828958D1 - Arzneiformulierungen zur hormonersatztherapie zur topischen anwendung auf der haut - Google Patents

Arzneiformulierungen zur hormonersatztherapie zur topischen anwendung auf der haut

Info

Publication number
DE69828958D1
DE69828958D1 DE69828958T DE69828958T DE69828958D1 DE 69828958 D1 DE69828958 D1 DE 69828958D1 DE 69828958 T DE69828958 T DE 69828958T DE 69828958 T DE69828958 T DE 69828958T DE 69828958 D1 DE69828958 D1 DE 69828958D1
Authority
DE
Germany
Prior art keywords
skin
hormonic
remedy
therapy
topical application
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Fee Related
Application number
DE69828958T
Other languages
English (en)
Other versions
DE69828958T2 (de
Inventor
M Samour
F Krauser
J Gyurik
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Macrochem Corp
Original Assignee
Macrochem Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Macrochem Corp filed Critical Macrochem Corp
Publication of DE69828958D1 publication Critical patent/DE69828958D1/de
Application granted granted Critical
Publication of DE69828958T2 publication Critical patent/DE69828958T2/de
Anticipated expiration legal-status Critical
Expired - Fee Related legal-status Critical Current

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K9/00—Medicinal preparations characterised by special physical form
    • A61K9/0012—Galenical forms characterised by the site of application
    • A61K9/0014—Skin, i.e. galenical aspects of topical compositions
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/08—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite containing oxygen, e.g. ethers, acetals, ketones, quinones, aldehydes, peroxides
    • A61K47/10—Alcohols; Phenols; Salts thereof, e.g. glycerol; Polyethylene glycols [PEG]; Poloxamers; PEG/POE alkyl ethers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K47/00—Medicinal preparations characterised by the non-active ingredients used, e.g. carriers or inert additives; Targeting or modifying agents chemically bound to the active ingredient
    • A61K47/06—Organic compounds, e.g. natural or synthetic hydrocarbons, polyolefins, mineral oil, petrolatum or ozokerite
    • A61K47/22—Heterocyclic compounds, e.g. ascorbic acid, tocopherol or pyrrolidones

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Epidemiology (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Dermatology (AREA)
  • Medicinal Preparation (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Prostheses (AREA)
DE69828958T 1997-10-16 1998-10-02 Arzneiformulierungen zur hormonersatztherapie zur topischen anwendung auf der haut Expired - Fee Related DE69828958T2 (de)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US953014 1997-10-16
US08/953,014 US5968919A (en) 1997-10-16 1997-10-16 Hormone replacement therapy drug formulations for topical application to the skin
PCT/US1998/020895 WO1999020257A1 (en) 1997-10-16 1998-10-02 Hormone replacement therapy drug formulations for topical application to the skin

Publications (2)

Publication Number Publication Date
DE69828958D1 true DE69828958D1 (de) 2005-03-17
DE69828958T2 DE69828958T2 (de) 2006-01-19

Family

ID=25493463

Family Applications (1)

Application Number Title Priority Date Filing Date
DE69828958T Expired - Fee Related DE69828958T2 (de) 1997-10-16 1998-10-02 Arzneiformulierungen zur hormonersatztherapie zur topischen anwendung auf der haut

Country Status (10)

Country Link
US (1) US5968919A (de)
EP (1) EP0971705B1 (de)
JP (1) JP2001505930A (de)
AT (1) ATE288744T1 (de)
CA (1) CA2260185C (de)
DE (1) DE69828958T2 (de)
DK (1) DK0971705T3 (de)
ES (1) ES2238094T3 (de)
PT (1) PT971705E (de)
WO (1) WO1999020257A1 (de)

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US20050020552A1 (en) * 2003-07-16 2005-01-27 Chaim Aschkenasy Pharmaceutical composition and method for transdermal drug delivery
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US20060110415A1 (en) * 2004-11-22 2006-05-25 Bioderm Research Topical Delivery System for Cosmetic and Pharmaceutical Agents
WO2007124250A2 (en) 2006-04-21 2007-11-01 Antares Pharma Ipl Ag Methods of treating hot flashes with formulations for transdermal or transmucosal application
WO2006125642A1 (en) 2005-05-27 2006-11-30 Antares Pharma Ipl Ag Methods and apparatus for transdermal or transmucosal application of testosterone
BRPI0611134A2 (pt) * 2005-06-03 2010-08-17 Acrux Dds Pty Ltd método e composição para liberação transdérmica de fármaco
CN101287470B (zh) 2005-10-12 2012-10-17 优尼麦德药物股份有限公司 改良的睾酮凝胶及使用方法
WO2008066618A2 (en) * 2006-10-20 2008-06-05 Skinvisible Pharmaceuticals, Inc. Antifungal composition and methods for using
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US8128913B1 (en) 2007-12-06 2012-03-06 Skinvisible Pharmaceuticals, Inc. Sunscreen composition with enhanced UV-A absorber stability and methods
US8299122B2 (en) * 2008-04-14 2012-10-30 Skinvisible Pharmaceuticals, Inc. Method for stabilizing retinoic acid, retinoic acid containing composition, and method of using a retinoic acid containing composition
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BR112014012444B1 (pt) 2011-11-23 2021-12-14 Therapeuticsmd, Inc Composição farmacêutica compreendendo estradiol solubilizado, progesterona e um agente de solubilização, bem como usos desta para tratar um sintoma relacionado à menopausa em uma mulher
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US10806697B2 (en) 2012-12-21 2020-10-20 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US20150196640A1 (en) 2012-06-18 2015-07-16 Therapeuticsmd, Inc. Progesterone formulations having a desirable pk profile
US10806740B2 (en) 2012-06-18 2020-10-20 Therapeuticsmd, Inc. Natural combination hormone replacement formulations and therapies
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US9180091B2 (en) 2012-12-21 2015-11-10 Therapeuticsmd, Inc. Soluble estradiol capsule for vaginal insertion
US10568891B2 (en) 2012-12-21 2020-02-25 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11266661B2 (en) 2012-12-21 2022-03-08 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US10471072B2 (en) 2012-12-21 2019-11-12 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
US11246875B2 (en) 2012-12-21 2022-02-15 Therapeuticsmd, Inc. Vaginal inserted estradiol pharmaceutical compositions and methods
USD750788S1 (en) 2013-11-26 2016-03-01 Acrux Dds Pty Ltd Topical spreading applicator
USD749225S1 (en) 2013-11-26 2016-02-09 Acrux Dds Pty Ltd Topical spreading applicator
JP2017516768A (ja) 2014-05-22 2017-06-22 セラピューティックスエムディー インコーポレーテッドＴｈｅｒａｐｅｕｔｉｃｓｍｄ， Ｉｎｃ． 天然の併用ホルモン補充療法剤及び療法
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US10328087B2 (en) 2015-07-23 2019-06-25 Therapeuticsmd, Inc. Formulations for solubilizing hormones
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EP3435977A4 (de) 2016-04-01 2019-10-16 Therapeuticsmd, Inc. Pharmazeutische steroidhormonzusammensetzung
US11633405B2 (en) 2020-02-07 2023-04-25 Therapeuticsmd, Inc. Steroid hormone pharmaceutical formulations
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Also Published As

Publication number Publication date
DK0971705T3 (da) 2005-06-13
EP0971705A4 (de) 2001-01-31
EP0971705A1 (de) 2000-01-19
ES2238094T3 (es) 2005-08-16
ATE288744T1 (de) 2005-02-15
CA2260185A1 (en) 1999-04-17
US5968919A (en) 1999-10-19
JP2001505930A (ja) 2001-05-08
CA2260185C (en) 2008-12-23
WO1999020257A1 (en) 1999-04-29
EP0971705B1 (de) 2005-02-09
PT971705E (pt) 2005-06-30
DE69828958T2 (de) 2006-01-19

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Legal Events

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8364 No opposition during term of opposition
8339 Ceased/non-payment of the annual fee